{
    "uniprot_canonical_ac": "A0A0G2JZX7-1",
    "uniprot_ac": "A0A0G2JZX7",
    "uniprot_id": "A0A0G2JZX7_RAT",
    "mass": {
        "chemical_mass": 54605.0,
        "monoisotopic_mass": 54605.0
    },
    "refseq": {
        "ac": "NP_001099998",
        "name": "zinc finger protein PLAGL2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099998"
    },
    "gene_names": [
        {
            "name": "Plagl2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7",
            "id": "A0A0G2JZX7"
        },
        {
            "name": "Plagl2_predicted",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7",
            "id": "A0A0G2JZX7"
        },
        {
            "name": "Plagl2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099998",
            "id": "NP_001099998"
        },
        {
            "name": "rCG_37391",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7",
            "id": "A0A0G2JZX7"
        }
    ],
    "protein_names": [
        {
            "name": "PLAG1-like zinc finger 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7#names_and_taxonomy",
            "id": "A0A0G2JZX7"
        },
        {
            "name": "Pleiomorphic adenoma gene-like 2 (Predicted), isoform CRA_b",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7#names_and_taxonomy",
            "id": "A0A0G2JZX7"
        },
        {
            "name": "pleiomorphic adenoma gene-like 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099998",
            "id": "NP_001099998"
        },
        {
            "name": "zinc finger protein PLAGL2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099998",
            "id": "NP_001099998"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2JZX7",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Plagl2",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7",
            "locus": {
                "chromosome": "3",
                "start_pos": 148722742,
                "end_pos": 148709531,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000010086",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000010086"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000010086",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000010086",
            "database": "Bgee"
        },
        {
            "id": "296281",
            "url": "https://www.ncbi.nlm.nih.gov/gene/296281",
            "database": "GeneID"
        },
        {
            "id": "IPR013087",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087",
            "database": "InterPro"
        },
        {
            "id": "IPR027765",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027765",
            "database": "InterPro"
        },
        {
            "id": "IPR036236",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236",
            "database": "InterPro"
        },
        {
            "id": "rno:296281",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:296281",
            "database": "KEGG Pathway"
        },
        {
            "id": "PTHR24408:SF20",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF20",
            "database": "PANTHER"
        },
        {
            "id": "PF00096",
            "url": "http://pfam.xfam.org/family/PF00096",
            "database": "Pfam"
        },
        {
            "id": "NP_001099998",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099998",
            "database": "RefSeq"
        },
        {
            "id": "1307999",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1307999",
            "database": "RGD"
        },
        {
            "id": "A0A0G2JZX7",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7",
            "database": "UniProtKB"
        },
        {
            "id": "A0A0G2JZX7-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7-1",
            "database": "UniProtKB"
        },
        {
            "id": "D3ZTE9",
            "url": "https://www.uniprot.org/uniprot/D3ZTE9",
            "database": "UniProtKB"
        },
        {
            "id": "D3ZTE9-1",
            "url": "https://www.uniprot.org/uniprot/D3ZTE9-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSLPHPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDMMGAKAFPGMLPMGMYGAHIPTMPSAGMPHSLVHNTLPMGMSYPLESSPISSSAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLTKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSAGAGGPLNFGPLHSLPPVFTSGLSTTTLPRFHQAFQ",
        "length": 496,
        "header": "tr|A0A0G2JZX7-1|A0A0G2JZX7_RAT Isoform 1 of PLAG1-like zinc finger 2  OS=Rattus norvegicus OX=10116 GN=Plagl2 PE=3 SV=1 CANONICAL=A0A0G2JZX7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2JZX7-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7#A0A0G2JZX7-1",
            "sequence": {
                "sequence": "MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSLPHPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDMMGAKAFPGMLPMGMYGAHIPTMPSAGMPHSLVHNTLPMGMSYPLESSPISSSAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLTKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSAGAGGPLNFGPLHSLPPVFTSGLSTTTLPRFHQAFQ",
                "length": 496,
                "header": "tr|A0A0G2JZX7-1|A0A0G2JZX7_RAT Isoform 1 of PLAG1-like zinc finger 2  OS=Rattus norvegicus OX=10116 GN=Plagl2 PE=3 SV=1 CANONICAL=A0A0G2JZX7-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 141703240,
                "end_pos": 141699060,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000097371.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000097371.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000077451.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000077451.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3ZTE9-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7#D3ZTE9-1",
            "sequence": {
                "sequence": "MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSLPHPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCNWVFSKYIMTPSSS",
                "length": 175,
                "header": "tr|D3ZTE9-1|D3ZTE9_RAT Computationally mapped isoform of PLAG1-like zinc finger 2  OS=Rattus norvegicus OX=10116 GN=Plagl2 PE=3 SV=1 CANONICAL=A0A0G2JZX7-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 141703240,
                "end_pos": 141698096,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000068592.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000068592.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000059668.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000059668.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "A zinc-finger protein, PLAGL2, induces the expression of a proapoptotic protein Nip3, leading to cellular apoptosis.",
            "journal": "The Journal of biological chemistry",
            "date": "2002",
            "authors": "Mizutani A, Furukawa T, Adachi Y, Ikehara S, Taketani S",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001099998",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099998"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11832486",
                    "url": "https://glygen.org/publication/PubMed/11832486"
                }
            ]
        },
        {
            "title": "Pleiomorphic adenoma gene-like-2, a zinc finger protein, transactivates the surfactant protein-C promoter.",
            "journal": "American journal of respiratory cell and molecular biology",
            "date": "2005",
            "authors": "Yang MC, Weissler JC, Terada LS, Deng F, Yang YS",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001099998",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099998"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15361364",
                    "url": "https://glygen.org/publication/PubMed/15361364"
                }
            ]
        },
        {
            "title": "High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.",
            "journal": "Nature",
            "date": "2013",
            "authors": "Hasson SA, Kane LA, Yamano K, Huang CH, Sliter DA, Buehler E, Wang C, Heman-Ackah SM, Hessa T, Guha R, Martin SE, Youle RJ",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001099998",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099998"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "24270810",
                    "url": "https://glygen.org/publication/PubMed/24270810"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:296281",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:296281",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q925T4-1",
            "protein_name": "Pleiomorphic adenoma gene-like 2",
            "gene_name": "Plagl2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSLPHPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGAKAFPGMLPMGMYGAHIPTMPSAGMPHSLVHNTLPMGMSYPLESSPISSSAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSAGAGGPLNFGPLHSLPPVFTSGLSTTTLPRFHQAFQ",
                "length": 496
            },
            "evidence": [
                {
                    "id": "41487207",
                    "url": "http://www.informatics.jax.org/homology/41487207",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q9UPG8-1",
            "protein_name": "Zinc finger protein PLAGL2",
            "gene_name": "PLAGL2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSLPQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGAHIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFTSGLSSTTLPRFHQAFQ",
                "length": 496
            },
            "evidence": [
                {
                    "id": "41487207",
                    "url": "http://www.informatics.jax.org/homology/41487207",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 7,
                "go_terms": [
                    {
                        "name": "transcription, DNA-templated",
                        "id": "GO:0006351",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of transcription by RNA polymerase II",
                        "id": "GO:0006357",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "lipid metabolic process",
                        "id": "GO:0006629",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of transcription by RNA polymerase II",
                        "id": "GO:0045944",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "post-embryonic development",
                        "id": "GO:0009791",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009791",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chylomicron assembly",
                        "id": "GO:0034378",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034378",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of intrinsic apoptotic signaling pathway",
                        "id": "GO:2001244",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001244",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 4,
                "go_terms": [
                    {
                        "name": "metal ion binding",
                        "id": "GO:0046872",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding",
                        "id": "GO:0000978",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "sequence-specific DNA binding",
                        "id": "GO:0043565",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "DNA-binding transcription activator activity, RNA polymerase II-specific",
                        "id": "GO:0001228",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZX7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZX7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 402,
            "end_pos": 404,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}