{
    "uniprot_canonical_ac": "A0A0G2JTY3-1",
    "uniprot_ac": "A0A0G2JTY3",
    "uniprot_id": "A0A0G2JTY3_RAT",
    "mass": {
        "chemical_mass": 48894.0,
        "monoisotopic_mass": 48894.0
    },
    "refseq": {
        "ac": "NP_113777",
        "name": "glucose-6-phosphate exchanger SLC37A4",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113777"
    },
    "gene_names": [
        {
            "name": "Slc37a4",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3",
            "id": "A0A0G2JTY3"
        }
    ],
    "protein_names": [
        {
            "name": "Solute carrier family 37 member 4",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3#names_and_taxonomy",
            "id": "A0A0G2JTY3"
        },
        {
            "name": "glucose-6-phosphatase, transport protein 1; solute carrier family 37 (glycerol-6-phosphate transporter), member 4; glucose-6-phosphate translocase; solute carrier family 37 (glucose-6-phosphate transporter), member 4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113777",
            "id": "NP_113777"
        },
        {
            "name": "glucose-6-phosphate exchanger SLC37A4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113777",
            "id": "NP_113777"
        }
    ],
    "function": [
        {
            "annotation": "Adipocytes are equipped with a functional G6PT-hexose-6-phosphate dehydrogenase-11beta-hydroxysteroid dehydrogenase type 1 system",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_113777",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113777"
                },
                {
                    "database": "PubMed",
                    "id": "17303657",
                    "url": "https://glygen.org/publication/PubMed/17303657"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:2749",
            "recommended_name": {
                "id": "DOID:2749",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:2749",
                "name": "glycogen storage disease I",
                "description": "A glycogen storage disease that has_material_basis_in deficiency of the glucose-6-phosphatase enzyme which impairs the ability of the liver to produce free glucose from glycogen and from gluconeogenesis and is characterized by accumulation of glycogen and fat in the liver and kidneys, resulting in hepatomegaly and renomegaly."
            },
            "synonyms": [
                {
                    "id": "DOID:2749",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2749",
                    "name": "Glycogen storage disease, type I",
                    "description": ""
                },
                {
                    "id": "DOID:2749",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2749",
                    "name": "deficiency of glucose-6-phosphatase",
                    "description": ""
                },
                {
                    "id": "DOID:2749",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2749",
                    "name": "glycogen storage disease type I",
                    "description": ""
                },
                {
                    "id": "DOID:2749",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2749",
                    "name": "glycogenosis type I",
                    "description": ""
                },
                {
                    "id": "DOID:2749",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2749",
                    "name": "von Gierke disease",
                    "description": ""
                },
                {
                    "id": "DOID:2749",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2749",
                    "name": "von Gierke's disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0009289",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009289",
                    "name": "glycogen storage disease IC",
                    "description": ""
                },
                {
                    "id": "MONDO:0009289",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009289",
                    "name": "glycogen storage disease Id",
                    "description": ""
                },
                {
                    "id": "MONDO:0009289",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009289",
                    "name": "glycogen storage disease type Ic",
                    "description": ""
                },
                {
                    "id": "MONDO:0009289",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009289",
                    "name": "GSD Ic",
                    "description": ""
                },
                {
                    "id": "MONDO:0009289",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009289",
                    "name": "glycogen storage disease Ic; GSD1C",
                    "description": ""
                },
                {
                    "id": "MONDO:0009289",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009289",
                    "name": "Gsd1C",
                    "description": ""
                },
                {
                    "id": "MONDO:0009289",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009289",
                    "name": "glycogen storage disease Ic",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glycogen storage disease due to glucose-6-phosphatase deficiency type IB",
                    "description": "Glycogenosis due to glucose-6-phosphatase deficiency (G6P) type b, or glycogen storage disease (GSD) type 1b, is a type of glycogenosis due to G6P deficiency (see this term)."
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "GSD due to G6P deficiency type IB",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glycogenosis due to glucose-6-phosphatase transport defect type IB",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "GSD1B",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glycogen storage disease due to G6P deficiency type IB",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "GSD type IB",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glycogen storage disease Ib; GSD1B",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "G6P deficiency type IB",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glycogen storage disease type IB",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "GSD Ib",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "G6PT deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glucose-6-phosphate Transport defect",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glycogenosis type 1b",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "GSD due to G6PT deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glycogen storage disease type I non-a",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "GSDIb",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "GSD type 1 non a",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glycogenosis due to glucose-6-phosphatase deficiency type 1b",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glycogen storage disease Ib",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "GSD type 1b",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glycogen storage disease type 1b",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "G6P translocase deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009288",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009288",
                    "name": "glycogenosis type IB",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogen storage disease due to glucose-6-phosphatase deficiency type IA",
                    "description": "Glycogenosis due to glucose-6-phosphatase deficiency (G6P) type a, or glycogen storage disease (GSD) type 1a, is a type of glycogenosis due to G6P deficiency (see this term)."
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "hepatorenal form of glycogen storage disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogenosis due to glucose-6-phosphatase deficiency type Ia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "GSD due to G6P deficiency type Ia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogen storage disease due to G6P deficiency type Ia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glucose-6-phosphatase deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "GSD1A",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogen storage disease Ia; GSD1A",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "hepatorenal glycogenosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "GSD1",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogen storage disease 1A",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogen storage disease type Ia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "Von Gierke disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "GSD Ia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogen storage disease caused by mutation in G6PC",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogenosis due to glucose-6-phosphatase deficiency type 1a",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "GSDIa",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "GSD due to G6P deficiency type 1a",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "G6PC glycogen storage disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "G6P deficiency type 1a",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glucose-6-phosphatase deficiency glycogen storage disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "GSD type 1a",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogen storage disease Ia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogen storage disease type 1a",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogenosis type Ia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009287",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009287",
                    "name": "glycogen storage disease 1",
                    "description": ""
                },
                {
                    "id": "MIM:232240",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/232240",
                    "name": "Glycogen storage disease 1C",
                    "description": "Glycogen storage disease 1C"
                },
                {
                    "id": "MIM:232220",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/232220",
                    "name": "Glycogen storage disease 1B",
                    "description": "Glycogen storage disease 1B"
                },
                {
                    "id": "MIM:232200",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/232200",
                    "name": "Glycogen storage disease 1A",
                    "description": "Glycogen storage disease 1A"
                }
            ],
            "evidence": [
                {
                    "id": "2749",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:2749"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2JTY3",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Slc37a4",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3",
            "locus": {
                "chromosome": "8",
                "start_pos": 48716939,
                "end_pos": 48723024,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000011361",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000011361"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000011361",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000011361",
            "database": "Bgee"
        },
        {
            "id": "29573",
            "url": "https://www.ncbi.nlm.nih.gov/gene/29573",
            "database": "GeneID"
        },
        {
            "id": "IPR000849",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000849",
            "database": "InterPro"
        },
        {
            "id": "IPR011701",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701",
            "database": "InterPro"
        },
        {
            "id": "IPR020846",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846",
            "database": "InterPro"
        },
        {
            "id": "IPR021159",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR021159",
            "database": "InterPro"
        },
        {
            "id": "IPR036259",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259",
            "database": "InterPro"
        },
        {
            "id": "NAWFQGW",
            "url": "https://omabrowser.org/oma/group/NAWFQGW/",
            "database": "OMA"
        },
        {
            "id": "621600at2759",
            "url": "http://www.orthodb.org/?query=621600at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PF07690",
            "url": "http://pfam.xfam.org/family/PF07690",
            "database": "Pfam"
        },
        {
            "id": "R-RNO-70263",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-70263",
            "database": "Reactome"
        },
        {
            "id": "NP_113777",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113777",
            "database": "RefSeq"
        },
        {
            "id": "XP_008764374",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008764374",
            "database": "RefSeq"
        },
        {
            "id": "62066",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=62066",
            "database": "RGD"
        },
        {
            "id": "A0A0G2JTY3",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3",
            "database": "UniProtKB"
        },
        {
            "id": "A0A0G2JTY3-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3-1",
            "database": "UniProtKB"
        },
        {
            "id": "F7EWB7",
            "url": "https://www.uniprot.org/uniprot/F7EWB7",
            "database": "UniProtKB"
        },
        {
            "id": "F7EWB7-1",
            "url": "https://www.uniprot.org/uniprot/F7EWB7-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MAITALSYSQPCSEATAFTTSTAKPSLLSCPPWWMRSLWTRTIWVSCSLLPFAAGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVTAFAALWFLNGLAQGLGWPPCGKILRKWFEPSQFGTWWAVLSTSMNLAGSLGPILATILAQSYSWRSTLALSGSLCVVVSFFCLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQDLLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQERGQSALVGSSYISALEVGGLVGSIAAGYLSDRAMAKAGLSVYGNPRHSLLLLMMAGMAASMFLFRVTVTSDSPKEAFWTPALHPLAELTGFTEHEIWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVICIASTVVFFLLRNIRTKMGRVSKKAE",
        "length": 455,
        "header": "tr|A0A0G2JTY3-1|A0A0G2JTY3_RAT Isoform 1 of Solute carrier family 37 member 4  OS=Rattus norvegicus OX=10116 GN=Slc37a4 PE=1 SV=2 CANONICAL=A0A0G2JTY3-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2JTY3-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3#A0A0G2JTY3-1",
            "sequence": {
                "sequence": "MAITALSYSQPCSEATAFTTSTAKPSLLSCPPWWMRSLWTRTIWVSCSLLPFAAGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVTAFAALWFLNGLAQGLGWPPCGKILRKWFEPSQFGTWWAVLSTSMNLAGSLGPILATILAQSYSWRSTLALSGSLCVVVSFFCLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQDLLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQERGQSALVGSSYISALEVGGLVGSIAAGYLSDRAMAKAGLSVYGNPRHSLLLLMMAGMAASMFLFRVTVTSDSPKEAFWTPALHPLAELTGFTEHEIWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVICIASTVVFFLLRNIRTKMGRVSKKAE",
                "length": 455,
                "header": "tr|A0A0G2JTY3-1|A0A0G2JTY3_RAT Isoform 1 of Solute carrier family 37 member 4  OS=Rattus norvegicus OX=10116 GN=Slc37a4 PE=1 SV=2 CANONICAL=A0A0G2JTY3-1"
            },
            "locus": {
                "chromosome": "8",
                "start_pos": 44728789,
                "end_pos": 44724818,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000089763.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000089763.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000068889.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068889.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F7EWB7-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3#F7EWB7-1",
            "sequence": {
                "sequence": "MAITALSYSQPCSEATAFTTSTAKPSLLSCPPWWMRSLWTRTIWVSCSLLPFAAGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVTAFAALWFLNGLAQGLGWPPCGKILRKWFEPSQFGTWWAVLSTSMNLAGSLGPILATILAQSYSWRSTLALSGSLCVVVSFFCLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQDLLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQERGQSALVGSSYISALEVGGLVGSIAAGYLSDRAMAKAGLSVYGNPRHSLLLLMMAGMAASMFLFRVTVTSDSPKIWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVICIASTVVFFLLRNIRTKMGRVSKKAE",
                "length": 434,
                "header": "tr|F7EWB7-1|F7EWB7_RAT Computationally mapped isoform of Solute carrier family 37 member 4  OS=Rattus norvegicus OX=10116 GN=Slc37a4 PE=1 SV=1 CANONICAL=A0A0G2JTY3-1"
            },
            "locus": {
                "chromosome": "8",
                "start_pos": 44728789,
                "end_pos": 44724818,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000015810.6",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000015810.6"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000015810.4",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000015810.4"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "The glucose-6-phosphate transporter-hexose-6-phosphate dehydrogenase-11beta-hydroxysteroid dehydrogenase type 1 system of the adipose tissue.",
            "journal": "Endocrinology",
            "date": "2007",
            "authors": "Marcolongo P, Piccirella S, Senesi S, Wunderlich L, Gerin I, Mandl J, Fulceri R, Banhegyi G, Benedetti A",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_113777",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113777"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "17303657",
                    "url": "https://glygen.org/publication/PubMed/17303657"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "R-RNO-70263",
            "name": "Gluconeogenesis",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-70263",
            "resource": "Reactome",
            "description": "Gluconeogenesis"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A1L1SUI3-1",
            "protein_name": "Solute carrier family 37 (glucose-6-phosphate transporter), member 4",
            "gene_name": "Slc37a4",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MAAQGYGYYRTVIFAAMFGGYSLYYFNRKTFSFVMPSLVDEIALDKDDLGLITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNVVFSWSSTVSAFAALWFLNGLAQGLGWPPCGKILRKWFEPSQFGTWWAVLSTSMNLAGSLGPILATILAQSYSWRSTLALSGALCVVVSFFCLLLIHNEPADVGLRNLDPAPSKGKKGSSKEESTLQDLLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQERGQSALVGSSYISALEVGGLVGSIAAGYLSDRAMAKAGLSLYGNPRHGLLLLMMAGMAASMFLFRVTVTSDSPKDAFWTPALHPLAELTGFTEHEIWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVVCGASTVVFFLLRNIRTKMGRVSKKGE",
                "length": 450
            },
            "evidence": [
                {
                    "id": "41492938",
                    "url": "http://www.informatics.jax.org/homology/41492938",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "O43826-1",
            "protein_name": "Glucose-6-phosphate exchanger SLC37A4",
            "gene_name": "SLC37A4",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MAAQGYGYYRTVIFSAMFGGYSLYYFNRKTFSFVMPSLVEEIPLDKDDLGFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFAWSSTVPVFAALWFLNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLGPILATILAQSYSWRSTLALSGALCVVVSFLCLLLIHNEPADVGLRNLDPMPSEGKKGSLKEESTLQELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMSALEVGGLVGSIAAGYLSDRAMAKAGLSNYGNPRHGLLLFMMAGMTVSMYLFRVTVTSDSPKLWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVICAASTAAFFLLRNIRTKMGRVSKKAE",
                "length": 429
            },
            "evidence": [
                {
                    "id": "41492938",
                    "url": "http://www.informatics.jax.org/homology/41492938",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 20,
                "go_terms": [
                    {
                        "name": "myeloid progenitor cell differentiation",
                        "id": "GO:0002318",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002318",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "triglyceride metabolic process",
                        "id": "GO:0006641",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006641",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to nutrient",
                        "id": "GO:0007584",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007584",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": "2996302"
                    },
                    {
                        "name": "glycogen metabolic process",
                        "id": "GO:0005977",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005977",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular calcium ion homeostasis",
                        "id": "GO:0006874",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to organic cyclic compound",
                        "id": "GO:0014070",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014070",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": "9753303"
                    },
                    {
                        "name": "positive regulation of catalytic activity",
                        "id": "GO:0043085",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043085",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "gluconeogenesis",
                        "id": "GO:0006094",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glucose homeostasis",
                        "id": "GO:0042593",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cholesterol homeostasis",
                        "id": "GO:0042632",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "response to glucose",
                        "id": "GO:0009749",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009749",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": "2996302"
                    },
                    {
                        "name": "steroid metabolic process",
                        "id": "GO:0008202",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008202",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "neutrophil homeostasis",
                        "id": "GO:0001780",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001780",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glucose-6-phosphate transport",
                        "id": "GO:0015760",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015760",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": "12062448"
                    },
                    {
                        "name": "neutrophil chemotaxis",
                        "id": "GO:0030593",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030593",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "respiratory burst",
                        "id": "GO:0045730",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045730",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lactate metabolic process",
                        "id": "GO:0006089",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006089",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of chemokine production",
                        "id": "GO:0032682",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032682",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "post-embryonic hemopoiesis",
                        "id": "GO:0035166",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035166",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "phosphate ion transmembrane transport",
                        "id": "GO:0035435",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035435",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "integral component of membrane",
                        "id": "GO:0016021",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": "9822626"
                    },
                    {
                        "name": "intracellular membrane-bounded organelle",
                        "id": "GO:0043231",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": "12062448"
                    },
                    {
                        "name": "endoplasmic reticulum membrane",
                        "id": "GO:0005789",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "integral component of endoplasmic reticulum membrane",
                        "id": "GO:0030176",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030176",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "glucose 6-phosphate:inorganic phosphate antiporter activity",
                        "id": "GO:0061513",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061513",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glucose-6-phosphate transmembrane transporter activity",
                        "id": "GO:0015152",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015152",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTY3",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY3"
                            }
                        ],
                        "pmid": "12062448"
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 380,
            "end_pos": 382,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}