{
    "uniprot_canonical_ac": "A0A0G2JTM9-1",
    "uniprot_ac": "A0A0G2JTM9",
    "uniprot_id": "A0A0G2JTM9_RAT",
    "mass": {
        "chemical_mass": 42142.0,
        "monoisotopic_mass": 42142.0
    },
    "refseq": {
        "ac": "NP_001102663",
        "name": "dnaJ homolog subfamily B member 14",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102663"
    },
    "gene_names": [
        {
            "name": "Dnajb14",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9",
            "id": "A0A0G2JTM9"
        },
        {
            "name": "Dnajb14",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102663",
            "id": "NP_001102663"
        },
        {
            "name": "LOC499716",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9",
            "id": "A0A0G2JTM9"
        },
        {
            "name": "rCG_29010",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9",
            "id": "A0A0G2JTM9"
        }
    ],
    "protein_names": [
        {
            "name": "DnaJ (Hsp40) homolog, subfamily B, member 14",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102663",
            "id": "NP_001102663"
        },
        {
            "name": "DnaJ heat shock protein family (Hsp40) member B14",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9#names_and_taxonomy",
            "id": "A0A0G2JTM9"
        },
        {
            "name": "Similar to DnaJ (Hsp40) homolog, subfamily B, member 14 isoform 1, isoform CRA_b",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9#names_and_taxonomy",
            "id": "A0A0G2JTM9"
        },
        {
            "name": "dnaJ homolog subfamily B member 14",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102663",
            "id": "NP_001102663"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:12858",
            "recommended_name": {
                "id": "DOID:12858",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:12858",
                "name": "Huntington's disease",
                "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities."
            },
            "synonyms": [
                {
                    "id": "DOID:12858",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:12858",
                    "name": "HD",
                    "description": ""
                },
                {
                    "id": "DOID:12858",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:12858",
                    "name": "Huntington disease",
                    "description": ""
                },
                {
                    "id": "DOID:12858",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:12858",
                    "name": "Huntington's chorea",
                    "description": ""
                },
                {
                    "id": "MONDO:0007739",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007739",
                    "name": "Huntington disease",
                    "description": "Huntington disease (HD) is a rare neurodegenerative disorder of the central nervous system characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia."
                },
                {
                    "id": "MONDO:0007739",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007739",
                    "name": "Huntington's disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0007739",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007739",
                    "name": "Huntington's chorea",
                    "description": ""
                },
                {
                    "id": "MONDO:0007739",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007739",
                    "name": "HD",
                    "description": ""
                },
                {
                    "id": "MONDO:0007739",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007739",
                    "name": "Huntington disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0007739",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007739",
                    "name": "Huntington disease; HD",
                    "description": ""
                },
                {
                    "id": "MONDO:0007739",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007739",
                    "name": "Huntington chorea",
                    "description": ""
                },
                {
                    "id": "MIM:143100",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/143100",
                    "name": "Huntington disease",
                    "description": "Huntington disease"
                }
            ],
            "evidence": [
                {
                    "id": "12858",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:12858"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2JTM9",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Dnajb14",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9",
            "locus": {
                "chromosome": "2",
                "start_pos": 243018975,
                "end_pos": 243151933,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000060107",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000060107"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000060107",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000060107",
            "database": "Bgee"
        },
        {
            "id": "cd06257",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257",
            "database": "CDD"
        },
        {
            "id": "499716",
            "url": "https://www.ncbi.nlm.nih.gov/gene/499716",
            "database": "GeneID"
        },
        {
            "id": "IPR001623",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623",
            "database": "InterPro"
        },
        {
            "id": "IPR015399",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR015399",
            "database": "InterPro"
        },
        {
            "id": "IPR018253",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253",
            "database": "InterPro"
        },
        {
            "id": "IPR036869",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869",
            "database": "InterPro"
        },
        {
            "id": "rno:499716",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:499716",
            "database": "KEGG Pathway"
        },
        {
            "id": "AYCRKPA",
            "url": "https://omabrowser.org/oma/group/AYCRKPA/",
            "database": "OMA"
        },
        {
            "id": "1173544at2759",
            "url": "http://www.orthodb.org/?query=1173544at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PF00226",
            "url": "http://pfam.xfam.org/family/PF00226",
            "database": "Pfam"
        },
        {
            "id": "PF09320",
            "url": "http://pfam.xfam.org/family/PF09320",
            "database": "Pfam"
        },
        {
            "id": "NP_001102663",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102663",
            "database": "RefSeq"
        },
        {
            "id": "1591949",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1591949",
            "database": "RGD"
        },
        {
            "id": "A0A0G2JTM9",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9",
            "database": "UniProtKB"
        },
        {
            "id": "A0A0G2JTM9-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MEGNRDEAEKCVQIAREALSAGNRDKAQRFLQKAEKLYPLPAARALLEIIMKNGSTAGNSTHCRKPPGSSDQSKPSFGKDGTSGAGEGGKVYTKDQVEGVLSINKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQYDLTGSEEEACSPQSNGRFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSFSNGRAAYSHQHQHRHSGHEREEERGDGGFSVFIQLMPVIVLILVSLLSQLMVSNPPYSLYPRSGQTIKMQTENLGVVYYVNKDFKSEYKGALLQKVEKSVEEDYVTNIRNNCWKERQQKTDMQYAAKVYRDERLRRKADALSMDNCKELERLTSLYKGG",
        "length": 377,
        "header": "tr|A0A0G2JTM9-1|A0A0G2JTM9_RAT Isoform 1 of Similar to DnaJ (Hsp40) homolog, subfamily B, member 14 isoform 1, isoform CRA_b  OS=Rattus norvegicus OX=10116 GN=Dnajb14 PE=4 SV=1 CANONICAL=A0A0G2JTM9-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2JTM9-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9#A0A0G2JTM9-1",
            "sequence": {
                "sequence": "MEGNRDEAEKCVQIAREALSAGNRDKAQRFLQKAEKLYPLPAARALLEIIMKNGSTAGNSTHCRKPPGSSDQSKPSFGKDGTSGAGEGGKVYTKDQVEGVLSINKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQYDLTGSEEEACSPQSNGRFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSFSNGRAAYSHQHQHRHSGHEREEERGDGGFSVFIQLMPVIVLILVSLLSQLMVSNPPYSLYPRSGQTIKMQTENLGVVYYVNKDFKSEYKGALLQKVEKSVEEDYVTNIRNNCWKERQQKTDMQYAAKVYRDERLRRKADALSMDNCKELERLTSLYKGG",
                "length": 377,
                "header": "tr|A0A0G2JTM9-1|A0A0G2JTM9_RAT Isoform 1 of Similar to DnaJ (Hsp40) homolog, subfamily B, member 14 isoform 1, isoform CRA_b  OS=Rattus norvegicus OX=10116 GN=Dnajb14 PE=4 SV=1 CANONICAL=A0A0G2JTM9-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 226401913,
                "end_pos": 226359019,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000081989.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000081989.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000068773.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068773.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Defining the membrane proteome of NK cells.",
            "journal": "Journal of mass spectrometry : JMS",
            "date": "2010",
            "authors": "Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001102663",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102663"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19946888",
                    "url": "https://glygen.org/publication/PubMed/19946888"
                }
            ]
        },
        {
            "title": "Tetrameric Assembly of K(+) Channels Requires ER-Located Chaperone Proteins.",
            "journal": "Molecular cell",
            "date": "2017",
            "authors": "Li K, Jiang Q, Bai X, Yang YF, Ruan MY, Cai SQ",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001102663",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001102663"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "27916661",
                    "url": "https://glygen.org/publication/PubMed/27916661"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:499716",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:499716",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q149L6-1",
            "protein_name": "DnaJ homolog subfamily B member 14",
            "gene_name": "Dnajb14",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MEGNRDEAEKCVQIAREALSAGNRDKAQRFLQKAEKLYPLPAARALLEIIMKNGSTAGSSTHCRKPPGSSDQSKPSCGKDGTSGAGEGGKVYTKDQVEGVLSINKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQYDLTGSEEQACNHQNNGRFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSFSNGRAAYSHQHQHRHSGHEREEERADGGFSVFIQLMPIIVLILVSLLSQLMVSNPPYSLYPRSGSGQTIKMQTENLGVVYYVSKDFKSEYKGTLLQKVEKSVEEDYVTNIRNNCWKERQQKTDMQYAAKVYRDEQLRRKADALSMENCKELERLTSLYKGG",
                "length": 379
            },
            "evidence": [
                {
                    "id": "41500563",
                    "url": "http://www.informatics.jax.org/homology/41500563",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q8TBM8-1",
            "protein_name": "DnaJ homolog subfamily B member 14",
            "gene_name": "DNAJB14",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MEGNRDEAEKCVEIAREALNAGNREKAQRFLQKAEKLYPLPSARALLEIIMKNGSTAGNSPHCRKPSGSGDQSKPNCTKDSTSGSGEGGKGYTKDQVDGVLSINKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQYDLTGNEEQACNHQNNGRFNFHRGCEADITPEDLFNIFFGGGFPSGSVHSFSNGRAGYSQQHQHRHSGHEREEERGDGGFSVFIQLMPIIVLILVSLLSQLMVSNPPYSLYPRSGTGQTIKMQTENLGVVYYVNKDFKNEYKGMLLQKVEKSVEEDYVTNIRNNCWKERQQKTDMQYAAKVYRDDRLRRKADALSMDNCKELERLTSLYKGG",
                "length": 379
            },
            "evidence": [
                {
                    "id": "41500563",
                    "url": "http://www.informatics.jax.org/homology/41500563",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "endoplasmic reticulum",
                        "id": "GO:0005783",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endoplasmic reticulum membrane",
                        "id": "GO:0005789",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 4,
                "go_terms": [
                    {
                        "name": "ubiquitin-dependent ERAD pathway",
                        "id": "GO:0030433",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030433",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "chaperone cofactor-dependent protein refolding",
                        "id": "GO:0051085",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051085",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to misfolded protein",
                        "id": "GO:0071218",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071218",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "protein-containing complex assembly",
                        "id": "GO:0065003",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "Hsp70 protein binding",
                        "id": "GO:0030544",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JTM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTM9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 53,
            "end_pos": 55,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 59,
            "end_pos": 61,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}