{
    "uniprot_canonical_ac": "A0A087WQL6-1",
    "uniprot_ac": "A0A087WQL6",
    "uniprot_id": "A0A087WQL6_MOUSE",
    "mass": {
        "chemical_mass": 6212.0,
        "monoisotopic_mass": 6212.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Krtap6-3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A087WQL6",
            "id": "A0A087WQL6"
        }
    ],
    "protein_names": [
        {
            "name": "Keratin-associated protein 6-3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A087WQL6#names_and_taxonomy",
            "id": "A0A087WQL6"
        }
    ],
    "function": [
        {
            "annotation": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "F6T6A9",
                    "url": "https://www.uniprot.org/uniprot/F6T6A9#function"
                },
                {
                    "database": "PubMed",
                    "id": "ARBA00003327",
                    "url": "https://glygen.org/publication/PubMed/ARBA00003327"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A087WQL6",
                    "url": "https://www.uniprot.org/uniprot/A0A087WQL6#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A087WQL6",
                    "url": "https://www.uniprot.org/uniprot/A0A087WQL6"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Krtap6-3",
            "url": "https://www.uniprot.org/uniprot/A0A087WQL6",
            "locus": {
                "chromosome": "16",
                "start_pos": 89084015,
                "end_pos": 89084534,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000057855",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000057855"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000057855",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000057855",
            "database": "Bgee"
        },
        {
            "id": "IPR021743",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR021743",
            "database": "InterPro"
        },
        {
            "id": "1330279",
            "url": "http://www.informatics.jax.org/marker/MGI:1330279",
            "database": "MGI"
        },
        {
            "id": "CYYANYY",
            "url": "https://omabrowser.org/oma/group/CYYANYY/",
            "database": "OMA"
        },
        {
            "id": "PF11759",
            "url": "http://pfam.xfam.org/family/PF11759",
            "database": "Pfam"
        },
        {
            "id": "R-MMU-6805567",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6805567",
            "database": "Reactome"
        },
        {
            "id": "A0A087WQL6",
            "url": "https://www.uniprot.org/uniprot/A0A087WQL6",
            "database": "UniProtKB"
        },
        {
            "id": "A0A087WQL6-1",
            "url": "https://www.uniprot.org/uniprot/A0A087WQL6-1",
            "database": "UniProtKB"
        },
        {
            "id": "F6T6A9",
            "url": "https://www.uniprot.org/uniprot/F6T6A9",
            "database": "UniProtKB"
        },
        {
            "id": "F6T6A9-1",
            "url": "https://www.uniprot.org/uniprot/F6T6A9-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MCYYRGYYGGLGYGYGGLGYGYGCGYGCGYGCGYGGYGGYGYGCCRPLCCRRYYGFY",
        "length": 57,
        "header": "tr|A0A087WQL6-1|A0A087WQL6_MOUSE Isoform 1 of Keratin-associated protein 6-3  OS=Mus musculus OX=10090 GN=Krtap6-3 PE=4 SV=1 CANONICAL=A0A087WQL6-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A087WQL6-1",
            "url": "https://www.uniprot.org/uniprot/A0A087WQL6#A0A087WQL6-1",
            "sequence": {
                "sequence": "MCYYRGYYGGLGYGYGGLGYGYGCGYGCGYGCGYGGYGGYGYGCCRPLCCRRYYGFY",
                "length": 57,
                "header": "tr|A0A087WQL6-1|A0A087WQL6_MOUSE Isoform 1 of Keratin-associated protein 6-3  OS=Mus musculus OX=10090 GN=Krtap6-3 PE=4 SV=1 CANONICAL=A0A087WQL6-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 88881141,
                "end_pos": 88880971,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000185581.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000185581.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000140246.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000140246.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F6T6A9-1",
            "url": "https://www.uniprot.org/uniprot/A0A087WQL6#F6T6A9-1",
            "sequence": {
                "sequence": "YRGYYGGLGYGYGGLGYGYGCGYGCGYGCGYGGYGGYGYGCCRPLCCRRYYGFY",
                "length": 54,
                "header": "tr|F6T6A9-1|A0A087WQL6_MOUSE Computationally mapped isoform of Keratin-associated protein 6-3  OS=Mus musculus OX=10090 GN=Krtap6-3 PE=4 SV=1 CANONICAL=A0A087WQL6-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 88881141,
                "end_pos": 88880980,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000079151.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000079151.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000078152.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000078152.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "R-MMU-6805567",
            "name": "Keratinization",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6805567",
            "resource": "Reactome",
            "description": "Keratinization"
        }
    ],
    "orthologs": [],
    "go_annotation": {},
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        }
    ]
}