{
    "uniprot_canonical_ac": "A0A075B5X2-1",
    "uniprot_ac": "A0A075B5X2",
    "uniprot_id": "A0A075B5X2_MOUSE",
    "mass": {
        "chemical_mass": 12900.0,
        "monoisotopic_mass": 12900.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Ighv1-63",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A075B5X2",
            "id": "A0A075B5X2"
        }
    ],
    "protein_names": [
        {
            "name": "Immunoglobulin heavy variable V1-63",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A075B5X2#names_and_taxonomy",
            "id": "A0A075B5X2"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A075B5X2",
                    "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Ighv1-63",
            "url": "https://www.uniprot.org/uniprot/A0A075B5X2",
            "locus": {
                "chromosome": "12",
                "start_pos": 115496058,
                "end_pos": 115495625,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000096672",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000096672"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000096672",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000096672",
            "database": "Bgee"
        },
        {
            "id": "IPR007110",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110",
            "database": "InterPro"
        },
        {
            "id": "IPR013106",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106",
            "database": "InterPro"
        },
        {
            "id": "IPR013783",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783",
            "database": "InterPro"
        },
        {
            "id": "IPR036179",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179",
            "database": "InterPro"
        },
        {
            "id": "3642755",
            "url": "http://www.informatics.jax.org/marker/MGI:3642755",
            "database": "MGI"
        },
        {
            "id": "WIGWAKQ",
            "url": "https://omabrowser.org/oma/group/WIGWAKQ/",
            "database": "OMA"
        },
        {
            "id": "PF07686",
            "url": "http://pfam.xfam.org/family/PF07686",
            "database": "Pfam"
        },
        {
            "id": "R-MMU-166663",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-166663",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-173623",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-173623",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-198933",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-198933",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-202733",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-202733",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-2029481",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2029481",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-2029482",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2029482",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-2029485",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2029485",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-2168880",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2168880",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-2454202",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2454202",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-2730905",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2730905",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-2871796",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2871796",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-2871809",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2871809",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-2871837",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2871837",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-5690714",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5690714",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-977606",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-977606",
            "database": "Reactome"
        },
        {
            "id": "R-MMU-983695",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-983695",
            "database": "Reactome"
        },
        {
            "id": "A0A075B5X2",
            "url": "https://www.uniprot.org/uniprot/A0A075B5X2",
            "database": "UniProtKB"
        },
        {
            "id": "A0A075B5X2-1",
            "url": "https://www.uniprot.org/uniprot/A0A075B5X2-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MEWSGVFIFLLSVTAGVHSQVQLQQSGAELVRPGTSVKMSCKASGYTFTNYWIGWAKQRPGHGLEWIGDIYPGGGYTNYNEKFKGKATLTADKSSSTAYMQFSSLTSEDSAIYYCAR",
        "length": 117,
        "header": "tr|A0A075B5X2-1|A0A075B5X2_MOUSE Isoform 1 of Immunoglobulin heavy variable V1-63  OS=Mus musculus OX=10090 GN=Ighv1-63 PE=4 SV=1 CANONICAL=A0A075B5X2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A075B5X2-1",
            "url": "https://www.uniprot.org/uniprot/A0A075B5X2#A0A075B5X2-1",
            "sequence": {
                "sequence": "MEWSGVFIFLLSVTAGVHSQVQLQQSGAELVRPGTSVKMSCKASGYTFTNYWIGWAKQRPGHGLEWIGDIYPGGGYTNYNEKFKGKATLTADKSSSTAYMQFSSLTSEDSAIYYCAR",
                "length": 117,
                "header": "tr|A0A075B5X2-1|A0A075B5X2_MOUSE Isoform 1 of Immunoglobulin heavy variable V1-63  OS=Mus musculus OX=10090 GN=Ighv1-63 PE=4 SV=1 CANONICAL=A0A075B5X2-1"
            },
            "locus": {
                "chromosome": "12",
                "start_pos": 115459678,
                "end_pos": 115459245,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000103534.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000103534.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000100315.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000100315.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "R-MMU-166663",
            "name": "Initial triggering of complement",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-166663",
            "resource": "Reactome",
            "description": "Initial triggering of complement"
        },
        {
            "id": "R-MMU-173623",
            "name": "Classical antibody-mediated complement activation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-173623",
            "resource": "Reactome",
            "description": "Classical antibody-mediated complement activation"
        },
        {
            "id": "R-MMU-198933",
            "name": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-198933",
            "resource": "Reactome",
            "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
        },
        {
            "id": "R-MMU-202733",
            "name": "Cell surface interactions at the vascular wall",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-202733",
            "resource": "Reactome",
            "description": "Cell surface interactions at the vascular wall"
        },
        {
            "id": "R-MMU-2029481",
            "name": "FCGR activation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2029481",
            "resource": "Reactome",
            "description": "FCGR activation"
        },
        {
            "id": "R-MMU-2029482",
            "name": "Regulation of actin dynamics for phagocytic cup formation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2029482",
            "resource": "Reactome",
            "description": "Regulation of actin dynamics for phagocytic cup formation"
        },
        {
            "id": "R-MMU-2029485",
            "name": "Role of phospholipids in phagocytosis",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2029485",
            "resource": "Reactome",
            "description": "Role of phospholipids in phagocytosis"
        },
        {
            "id": "R-MMU-2168880",
            "name": "Scavenging of heme from plasma",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2168880",
            "resource": "Reactome",
            "description": "Scavenging of heme from plasma"
        },
        {
            "id": "R-MMU-2454202",
            "name": "Fc epsilon receptor (FCERI) signaling",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2454202",
            "resource": "Reactome",
            "description": "Fc epsilon receptor (FCERI) signaling"
        },
        {
            "id": "R-MMU-2730905",
            "name": "Role of LAT2/NTAL/LAB on calcium mobilization",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2730905",
            "resource": "Reactome",
            "description": "Role of LAT2/NTAL/LAB on calcium mobilization"
        },
        {
            "id": "R-MMU-2871796",
            "name": "FCERI mediated MAPK activation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2871796",
            "resource": "Reactome",
            "description": "FCERI mediated MAPK activation"
        },
        {
            "id": "R-MMU-2871809",
            "name": "FCERI mediated Ca+2 mobilization",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2871809",
            "resource": "Reactome",
            "description": "FCERI mediated Ca+2 mobilization"
        },
        {
            "id": "R-MMU-2871837",
            "name": "FCERI mediated NF-kB activation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2871837",
            "resource": "Reactome",
            "description": "FCERI mediated NF-kB activation"
        },
        {
            "id": "R-MMU-5690714",
            "name": "CD22 mediated BCR regulation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5690714",
            "resource": "Reactome",
            "description": "CD22 mediated BCR regulation"
        },
        {
            "id": "R-MMU-977606",
            "name": "Regulation of Complement cascade",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-977606",
            "resource": "Reactome",
            "description": "Regulation of Complement cascade"
        },
        {
            "id": "R-MMU-983695",
            "name": "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-983695",
            "resource": "Reactome",
            "description": "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "immunoglobulin receptor binding",
                        "id": "GO:0034987",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034987",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B5X2",
                                "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "antigen binding",
                        "id": "GO:0003823",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B5X2",
                                "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 7,
                "go_terms": [
                    {
                        "name": "phagocytosis, engulfment",
                        "id": "GO:0006911",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006911",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B5X2",
                                "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "innate immune response",
                        "id": "GO:0045087",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B5X2",
                                "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "B cell receptor signaling pathway",
                        "id": "GO:0050853",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B5X2",
                                "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "defense response to bacterium",
                        "id": "GO:0042742",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B5X2",
                                "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "phagocytosis, recognition",
                        "id": "GO:0006910",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006910",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B5X2",
                                "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "positive regulation of B cell activation",
                        "id": "GO:0050871",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050871",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B5X2",
                                "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "complement activation, classical pathway",
                        "id": "GO:0006958",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B5X2",
                                "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "external side of plasma membrane",
                        "id": "GO:0009897",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B5X2",
                                "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "immunoglobulin complex, circulating",
                        "id": "GO:0042571",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042571",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B5X2",
                                "url": "https://www.uniprot.org/uniprot/A0A075B5X2"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": []
}