{
    "disease_id": "DOID:12177",
    "recommended_name": {
        "id": "DOID:12177",
        "resource": "Disease Ontology",
        "url": "http://disease-ontology.org/term/DOID:12177",
        "name": "common variable immunodeficiency",
        "description": "An agammaglobulinemia that is results in insufficient production of antibodies needed to respond to exposure of pathogens and is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells."
    },
    "synonyms": [
        {
            "id": "DOID:12177",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:12177",
            "name": "CVID",
            "description": ""
        },
        {
            "id": "DOID:12177",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:12177",
            "name": "acquired agammaglobulinemia",
            "description": ""
        },
        {
            "id": "DOID:12177",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:12177",
            "name": "acquired hypogammaglobulinemia",
            "description": ""
        },
        {
            "id": "DOID:12177",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:12177",
            "name": "common variable agammaglobulinemia",
            "description": ""
        },
        {
            "id": "DOID:12177",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:12177",
            "name": "sporadic hypogammaglobulinemia",
            "description": ""
        },
        {
            "id": "MONDO:0014260",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014260",
            "name": "immunodeficiency, common variable, 10",
            "description": "Any common variable immunodeficiency in which the cause of the disease is a mutation in the NFKB2 gene."
        },
        {
            "id": "MONDO:0014260",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014260",
            "name": "NFKB2 common variable immunodeficiency",
            "description": ""
        },
        {
            "id": "MONDO:0014260",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014260",
            "name": "immunodeficiency, common variable, type 10",
            "description": ""
        },
        {
            "id": "MONDO:0014260",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014260",
            "name": "immunodeficiency, common variable, with central adrenal insufficiency",
            "description": ""
        },
        {
            "id": "MONDO:0014260",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014260",
            "name": "immunodeficiency, common variable, 10; CVID10",
            "description": ""
        },
        {
            "id": "MONDO:0014260",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014260",
            "name": "immunodeficiency, common variable, 10",
            "description": ""
        },
        {
            "id": "MONDO:0014260",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014260",
            "name": "Deficit in anterior pituitary function and variable immunodeficiency",
            "description": ""
        },
        {
            "id": "MONDO:0014260",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014260",
            "name": "CVID10",
            "description": ""
        },
        {
            "id": "MONDO:0014260",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014260",
            "name": "common variable immunodeficiency caused by mutation in NFKB2",
            "description": ""
        },
        {
            "id": "MONDO:0014338",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014338",
            "name": "IL21-related infantile inflammatory bowel disease",
            "description": ""
        },
        {
            "id": "MONDO:0014338",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014338",
            "name": "immunodeficiency, common variable, 11",
            "description": ""
        },
        {
            "id": "MONDO:0014338",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014338",
            "name": "immunodeficiency, common variable, type 11",
            "description": ""
        },
        {
            "id": "MONDO:0014338",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014338",
            "name": "IL21-related infantile IBD",
            "description": ""
        },
        {
            "id": "MONDO:0014338",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014338",
            "name": "immunodeficiency, common variable, 11; CVID11",
            "description": ""
        },
        {
            "id": "MONDO:0014338",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014338",
            "name": "CVID11",
            "description": ""
        },
        {
            "id": "MONDO:0014338",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014338",
            "name": "IL21 deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0013284",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013284",
            "name": "immunodeficiency, common variable, 4",
            "description": ""
        },
        {
            "id": "MONDO:0013284",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013284",
            "name": "immunodeficiency, common variable, 4; CVID4",
            "description": ""
        },
        {
            "id": "MONDO:0013284",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013284",
            "name": "immunodeficiency, common variable, 4",
            "description": ""
        },
        {
            "id": "MONDO:0013284",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013284",
            "name": "immunodeficiency, common variable, type 4",
            "description": ""
        },
        {
            "id": "MONDO:0013284",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013284",
            "name": "CVID4",
            "description": ""
        },
        {
            "id": "MONDO:0013284",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013284",
            "name": "antibody deficiency due to Baffr defect",
            "description": ""
        },
        {
            "id": "MONDO:0009413",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009413",
            "name": "immunodeficiency, common variable, 2",
            "description": ""
        },
        {
            "id": "MONDO:0009413",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009413",
            "name": "hypogammaglobulinemia due to TACI deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0009413",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009413",
            "name": "antibody deficiency due to TACI defect",
            "description": ""
        },
        {
            "id": "MONDO:0009413",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009413",
            "name": "immunodeficiency, common variable, type 2",
            "description": ""
        },
        {
            "id": "MONDO:0009413",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009413",
            "name": "CVID2",
            "description": ""
        },
        {
            "id": "MONDO:0009413",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009413",
            "name": "immunodeficiency, common variable, 2; CVID2",
            "description": ""
        },
        {
            "id": "MONDO:0009413",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0009413",
            "name": "immunodeficiency, common variable, 2",
            "description": ""
        },
        {
            "id": "MONDO:0011864",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011864",
            "name": "immunodeficiency, common variable, 1",
            "description": ""
        },
        {
            "id": "MONDO:0011864",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011864",
            "name": "immunodeficiency, common variable, 1; CVID1",
            "description": ""
        },
        {
            "id": "MONDO:0011864",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011864",
            "name": "immunodeficiency, common variable",
            "description": ""
        },
        {
            "id": "MONDO:0011864",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011864",
            "name": "immunodeficiency, common variable, 1",
            "description": ""
        },
        {
            "id": "MONDO:0011864",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011864",
            "name": "antibody deficiency due to Icos defect",
            "description": ""
        },
        {
            "id": "MONDO:0011864",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011864",
            "name": "immunodeficiency, common variable, type 1",
            "description": ""
        },
        {
            "id": "MONDO:0011864",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011864",
            "name": "CVID1",
            "description": ""
        },
        {
            "id": "MONDO:0013862",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013862",
            "name": "immunodeficiency, common variable, 7",
            "description": ""
        },
        {
            "id": "MONDO:0013862",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013862",
            "name": "immunodeficiency, common variable, 7",
            "description": ""
        },
        {
            "id": "MONDO:0013862",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013862",
            "name": "immunodeficiency, common variable, 7; CVID7",
            "description": ""
        },
        {
            "id": "MONDO:0013862",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013862",
            "name": "CVID7",
            "description": ""
        },
        {
            "id": "MONDO:0013862",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013862",
            "name": "immunodeficiency, common variable, type 7",
            "description": ""
        },
        {
            "id": "MONDO:0013863",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013863",
            "name": "combined immunodeficiency due to LRBA deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0013863",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013863",
            "name": "immunodeficiency, common variable, 8, with autoimmunity",
            "description": ""
        },
        {
            "id": "MONDO:0013863",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013863",
            "name": "CVID8",
            "description": ""
        },
        {
            "id": "MONDO:0013863",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013863",
            "name": "Cid due to LRBA deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0013863",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013863",
            "name": "immunodeficiency, common variable, 8, with autoimmunity; CVID8",
            "description": ""
        },
        {
            "id": "MONDO:0013283",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013283",
            "name": "immunodeficiency, common variable, 3",
            "description": ""
        },
        {
            "id": "MONDO:0013283",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013283",
            "name": "immunodeficiency, common variable, type 3",
            "description": ""
        },
        {
            "id": "MONDO:0013283",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013283",
            "name": "CVID3",
            "description": ""
        },
        {
            "id": "MONDO:0013283",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013283",
            "name": "antibody deficiency due to CD19 defect",
            "description": ""
        },
        {
            "id": "MONDO:0013283",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013283",
            "name": "immunodeficiency, common variable, 3; CVID3",
            "description": ""
        },
        {
            "id": "MONDO:0013283",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013283",
            "name": "immunodeficiency, common variable, 3",
            "description": ""
        },
        {
            "id": "MONDO:0013286",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013286",
            "name": "immunodeficiency, common variable, 6",
            "description": "Any common variable immunodeficiency in which the cause of the disease is a mutation in the CD81 gene."
        },
        {
            "id": "MONDO:0013286",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013286",
            "name": "CD81 common variable immunodeficiency",
            "description": ""
        },
        {
            "id": "MONDO:0013286",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013286",
            "name": "immunodeficiency, common variable, 6",
            "description": ""
        },
        {
            "id": "MONDO:0013286",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013286",
            "name": "antibody deficiency due to CD81 defect",
            "description": ""
        },
        {
            "id": "MONDO:0013286",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013286",
            "name": "immunodeficiency, common variable, 6; CVID6",
            "description": ""
        },
        {
            "id": "MONDO:0013286",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013286",
            "name": "immunodeficiency, common variable, type 6",
            "description": ""
        },
        {
            "id": "MONDO:0013286",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013286",
            "name": "CVID6",
            "description": ""
        },
        {
            "id": "MONDO:0013286",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013286",
            "name": "common variable immunodeficiency caused by mutation in CD81",
            "description": ""
        },
        {
            "id": "MONDO:0013285",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013285",
            "name": "immunodeficiency, common variable, 5",
            "description": "Any common variable immunodeficiency in which the cause of the disease is a mutation in the MS4A1 gene."
        },
        {
            "id": "MONDO:0013285",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013285",
            "name": "immunodeficiency, common variable, 5",
            "description": ""
        },
        {
            "id": "MONDO:0013285",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013285",
            "name": "immunodeficiency, common variable, 5; CVID5",
            "description": ""
        },
        {
            "id": "MONDO:0013285",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013285",
            "name": "MS4A1 common variable immunodeficiency",
            "description": ""
        },
        {
            "id": "MONDO:0013285",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013285",
            "name": "antibody deficiency due to CD20 defect",
            "description": ""
        },
        {
            "id": "MONDO:0013285",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013285",
            "name": "immunodeficiency, common variable, type 5",
            "description": ""
        },
        {
            "id": "MONDO:0013285",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013285",
            "name": "CVID5",
            "description": ""
        },
        {
            "id": "MONDO:0013285",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013285",
            "name": "common variable immunodeficiency caused by mutation in MS4A1",
            "description": ""
        },
        {
            "id": "MIM:615577",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/615577",
            "name": "Immunodeficiency, common variable, 10",
            "description": "Immunodeficiency, common variable, 10"
        },
        {
            "id": "MIM:615767",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/615767",
            "name": "Immunodeficiency, common variable, 11",
            "description": "Immunodeficiency, common variable, 11"
        },
        {
            "id": "MIM:613494",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/613494",
            "name": "Immunodeficiency, common variable, 4",
            "description": "Immunodeficiency, common variable, 4"
        },
        {
            "id": "MIM:240500",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/240500",
            "name": "Immunodeficiency, common variable, 2",
            "description": "Immunodeficiency, common variable, 2"
        },
        {
            "id": "MIM:607594",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/607594",
            "name": "Immunodeficiency, common variable, 1",
            "description": "Immunodeficiency, common variable, 1"
        },
        {
            "id": "MIM:614699",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/614699",
            "name": "Immunodeficiency, common variable, 7",
            "description": "Immunodeficiency, common variable, 7"
        },
        {
            "id": "MIM:614700",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/614700",
            "name": "Immunodeficiency, common variable, 8, with autoimmunity",
            "description": "Immunodeficiency, common variable, 8, with autoimmunity"
        },
        {
            "id": "MIM:613493",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/613493",
            "name": "Immunodeficiency, common variable, 3",
            "description": "Immunodeficiency, common variable, 3"
        },
        {
            "id": "MIM:613496",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/613496",
            "name": "Immunodeficiency, common variable, 6",
            "description": "Immunodeficiency, common variable, 6"
        },
        {
            "id": "MIM:613495",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/613495",
            "name": "Immunodeficiency, common variable, 5",
            "description": "Immunodeficiency, common variable, 5"
        }
    ]
}