{
    "disease_id": "DOID:0111902",
    "recommended_name": {
        "id": "DOID:0111902",
        "resource": "Disease Ontology",
        "url": "http://disease-ontology.org/term/DOID:0111902",
        "name": "thrombophilia due to activated protein C resistance",
        "description": "A thrombophilia characterized by resistance of F5 to cleavage and inactivation and increased tendency for thrombosis that has_material_basis_in heterozygous mutation in F5 on chromosome 1q24.2."
    },
    "synonyms": [
        {
            "id": "DOID:0111902",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111902",
            "name": "APC resistance",
            "description": ""
        },
        {
            "id": "DOID:0111902",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111902",
            "name": "PCCF deficiency",
            "description": ""
        },
        {
            "id": "DOID:0111902",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111902",
            "name": "PROC cofactor deficiency",
            "description": ""
        },
        {
            "id": "DOID:0111902",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111902",
            "name": "THPH2",
            "description": ""
        },
        {
            "id": "DOID:0111902",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111902",
            "name": "activated protein C resistance",
            "description": ""
        },
        {
            "id": "DOID:0111902",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111902",
            "name": "thrombophilia V",
            "description": ""
        },
        {
            "id": "DOID:0111902",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0111902",
            "name": "thrombophilia due to deficiency of activated protein C cofactor",
            "description": ""
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "thrombophilia due to activated protein C resistance",
            "description": "A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance."
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "APC resistance",
            "description": ""
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "thrombophilia due to deficiency of Activated Protein C cofactor",
            "description": ""
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "thrombophilia due to ACTIVATED PROTEIN C resistance; THPH2",
            "description": ""
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "thrombophilia due to activated protein C resistance",
            "description": ""
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "thrombophilia due to Factor 5 Leiden",
            "description": ""
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "Proc cofactor deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "Pccf deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "Activated Protein C resistance",
            "description": ""
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "thrombophilia 5",
            "description": ""
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "THPH2",
            "description": ""
        },
        {
            "id": "MONDO:0008560",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008560",
            "name": "resistance, APC",
            "description": ""
        },
        {
            "id": "MIM:188055",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/188055",
            "name": "Thrombophilia due to activated protein C resistance",
            "description": "Thrombophilia due to activated protein C resistance"
        }
    ]
}