{
    "disease_id": "DOID:0110816",
    "recommended_name": {
        "id": "DOID:0110816",
        "resource": "Disease Ontology",
        "url": "http://disease-ontology.org/term/DOID:0110816",
        "name": "hereditary spastic paraplegia 7",
        "description": "A hereditary spastic paraplegia that is characterized by slowly progressive onset, usually between 18-60 years of age, and generally more severe spasticity and has_material_basis_in mutation in the SPG7 gene on chromosome 16q24."
    },
    "synonyms": [
        {
            "id": "DOID:0110816",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0110816",
            "name": "SPG7",
            "description": ""
        },
        {
            "id": "DOID:0110816",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0110816",
            "name": "autosomal recessive spastic paraplegia 7",
            "description": ""
        },
        {
            "id": "DOID:0110816",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0110816",
            "name": "spastic paraplegia type 7",
            "description": ""
        },
        {
            "id": "MONDO:0011803",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011803",
            "name": "hereditary spastic paraplegia 7",
            "description": "Autosomal recessive spastic paraplegia type 7 is a form of hereditary spastic paraplegia (see this term) characterized by an onset usually in adulthood (but ranging from 10-72 years) of progressive bilateral lower limb weakness and spasticity, sphincter dysfunction, decreased vibratory sense at the ankles and with additional manifestations including optical neuropathy, nystagmus, strabismus, decreased hearing, scoliosis, pes cavus, motor and sensory neuropathy, amyotrophy, blepharoptosis and ophthalmoplegia."
        },
        {
            "id": "MONDO:0011803",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011803",
            "name": "spastic paraplegia 7, autosomal recessive",
            "description": ""
        },
        {
            "id": "MONDO:0011803",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011803",
            "name": "spastic paraplegia type 7",
            "description": ""
        },
        {
            "id": "MONDO:0011803",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011803",
            "name": "spastic paraplegia 7",
            "description": ""
        },
        {
            "id": "MONDO:0011803",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011803",
            "name": "hereditary spastic paraplegia type 7",
            "description": ""
        },
        {
            "id": "MONDO:0011803",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011803",
            "name": "spastic paraplegia 7, autosomal recessive; SPG7",
            "description": ""
        },
        {
            "id": "MONDO:0011803",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011803",
            "name": "hereditary spastic paraplegia caused by mutation in SPG7",
            "description": ""
        },
        {
            "id": "MONDO:0011803",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011803",
            "name": "SPG7 hereditary spastic paraplegia",
            "description": ""
        },
        {
            "id": "MONDO:0011803",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011803",
            "name": "autosomal recessive spastic paraplegia 7",
            "description": ""
        },
        {
            "id": "MONDO:0011803",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011803",
            "name": "hereditary spastic paraplegia paraplegin type",
            "description": ""
        },
        {
            "id": "MONDO:0011803",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011803",
            "name": "SPG7",
            "description": ""
        },
        {
            "id": "MIM:607259",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/607259",
            "name": "Spastic paraplegia 7, autosomal recessive",
            "description": "Spastic paraplegia 7, autosomal recessive"
        }
    ]
}