{
    "disease_id": "DOID:0110773",
    "recommended_name": {
        "id": "DOID:0110773",
        "resource": "Disease Ontology",
        "url": "http://disease-ontology.org/term/DOID:0110773",
        "name": "hereditary spastic paraplegia 2",
        "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the PLP1 gene on chromosome Xq22.2."
    },
    "synonyms": [
        {
            "id": "DOID:0110773",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0110773",
            "name": "SPG2",
            "description": ""
        },
        {
            "id": "DOID:0110773",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0110773",
            "name": "X-linked spastic paraplegia 2",
            "description": ""
        },
        {
            "id": "DOID:0110773",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0110773",
            "name": "spastic paraplegia type 2",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "hereditary spastic paraplegia 2",
            "description": "Spastic paraplegia type 2 (SPG2) is an X-linked leukodystrophy characterized primarily by spastic gait and autonomic dysfunction. When additional central nervous system (CNS) signs, such as intellectual deficit, ataxia, or extrapyramidal signs, are present, the syndrome is referred to as complicated SPG."
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "X-linked spastic paraplegia type 2",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "Sppx2",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "spastic paraplegia 2",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "SPG2",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "X-linked spastic paraplegia 2",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "hereditary spastic paraplegia type 2",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "spastic paraplegia 2, X-linked; SPG2",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "spastic paraplegia type 2",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "spastic paraplegia 2, X-linked",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "hereditary spastic paraplegia caused by mutation in PLP1",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "PLP1 hereditary spastic paraplegia",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "spastic gait type 2",
            "description": ""
        },
        {
            "id": "MONDO:0010733",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010733",
            "name": "spastic paraparesis type 2",
            "description": ""
        },
        {
            "id": "MIM:312920",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/312920",
            "name": "Spastic paraplegia 2, X-linked",
            "description": "Spastic paraplegia 2, X-linked"
        }
    ]
}