{
    "disease_id": "DOID:0110725",
    "recommended_name": {
        "id": "DOID:0110725",
        "resource": "Disease Ontology",
        "url": "http://disease-ontology.org/term/DOID:0110725",
        "name": "neuronal ceroid lipofuscinosis 10",
        "description": "A neuronal ceroid lipofuscinosis that has_material_basis_in homozygous or compound heterozygous mutation in the CTSD gene on chromosome 11p15."
    },
    "synonyms": [
        {
            "id": "DOID:0110725",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0110725",
            "name": "neuronal ceroid lipofuscinosis due to cathepsin D deficiency",
            "description": ""
        },
        {
            "id": "DOID:0110725",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0110725",
            "name": "CLN10",
            "description": ""
        },
        {
            "id": "DOID:0110725",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0110725",
            "name": "Cathepsin D deficiency",
            "description": ""
        },
        {
            "id": "DOID:0110725",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:0110725",
            "name": "neuronal ceroid lipofuscinosis cathepsin D-deficient",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "neuronal ceroid lipofuscinosis 10",
            "description": "Neuronal ceroid lipofuscinosis 10(CLN10-NCL) is arare condition that affects the nervous system. Signs and symptoms of the condition can develop any time from birth to adulthood and may include progressive dementia , seizures, lack of muscle coordination, and vision loss. CLN10-NCL is caused by changes ( mutations ) in the CTSD gene and is inherited in an autosomal recessive manner. Treatment options are limited to therapies that can help relieve some of the symptoms."
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "CLN10 disease, congenital (subtype)",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "neuronal ceroid lipofuscinosis due to cathepsin D deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "neuronal ceroid lipofuscinosis cathepsin D-deficient",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "CLN10 disease, adult (subtype)",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "CLN10 disease, late infantile (subtype)",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "ceroid lipofuscinosis neuronal Cathepsin D-deficient",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "CLN10",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "neuronal ceroid lipofuscinosis, congenital",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "neuronal ceroid lipofuscinosis type 10",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "CTSD neuronal ceroid lipofuscinosis",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "ceroid lipofuscinosis, neuronal, Cathepsin D-deficient",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "CLN10 disease, juvenile (subtype)",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "CLN10 disease",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "ceroid lipofuscinosis, neuronal, 10; CLN10",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "Cathepsin D deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "ceroid lipofuscinosis, neuronal, type 10",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "neuronal ceroid lipofuscinosis due to Cathepsin D deficiency",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "ceroid lipofuscinosis, neuronal, 10",
            "description": ""
        },
        {
            "id": "MONDO:0012414",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012414",
            "name": "neuronal ceroid lipofuscinosis caused by mutation in CTSD",
            "description": ""
        },
        {
            "id": "MIM:610127",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/610127",
            "name": "Ceroid lipofuscinosis, neuronal, 10",
            "description": "Ceroid lipofuscinosis, neuronal, 10"
        }
    ]
}