{ "uniprot_canonical_ac": "A2VD12-1", "uniprot_ac": "A2VD12", "uniprot_id": "PBIP1_RAT", "mass": { "chemical_mass": 80276.0, "monoisotopic_mass": 80276.0 }, "refseq": { "ac": "NP_001094446", "name": "pre-B-cell leukemia transcription factor-interacting protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094446" }, "gene_names": [ { "name": "Pbxip1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2VD12", "id": "A2VD12" }, { "name": "Hpip", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2VD12", "id": "A2VD12" }, { "name": "Pbxip1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094446", "id": "NP_001094446" } ], "protein_names": [ { "name": "Pre-B-cell leukemia transcription factor-interacting protein 1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2VD12#names_and_taxonomy", "id": "A2VD12" }, { "name": "Hematopoietic PBX-interacting protein", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2VD12#names_and_taxonomy", "id": "A2VD12" }, { "name": "hematopoietic PBX-interacting protein; pre-B-cell leukemia homeobox interacting protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094446", "id": "NP_001094446" }, { "name": "pre-B-cell leukemia transcription factor-interacting protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094446", "id": "NP_001094446" } ], "function": [ { "annotation": "Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "common_name": "Rat" } ], "gene": [ { "name": "Pbxip1", "url": "https://www.uniprot.org/uniprot/A2VD12", "locus": { "chromosome": "2", "start_pos": 188766535, "end_pos": 188776439, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000020673", "url": "https://www.ensembl.org/id/ENSRNOG00000020673" } ] } } ], "crossref": [ { "id": "ENSRNOG00000020673", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000020673", "database": "Bgee" }, { "id": "310644", "url": "https://www.ncbi.nlm.nih.gov/gene/310644", "database": "GeneID" }, { "id": "IPR033589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033589", "database": "InterPro" }, { "id": "rno:310644", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:310644", "database": "KEGG Pathway" }, { "id": "LMQQPKG", "url": "https://omabrowser.org/oma/group/LMQQPKG/", "database": "OMA" }, { "id": "640123at2759", "url": "http://www.orthodb.org/?query=640123at2759", "database": "OrthoDB" }, { "id": "PTHR28638:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28638:SF1", "database": "PANTHER" }, { "id": "PR_A2VD12", "url": "http://purl.obolibrary.org/obo/PR_A2VD12", "database": "PRO" }, { "id": "NP_001094446", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094446", "database": "RefSeq" }, { "id": "1305180", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1305180", "database": "RGD" }, { "id": "A2VD12", "url": "http://unicarbkb.org/proteinsummary/A2VD12/annotated", "database": "UniCarbKB" }, { "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12", "database": "UniProtKB" }, { "id": "A2VD12-1", "url": "https://www.uniprot.org/uniprot/A2VD12-1", "database": "UniProtKB" } ], "sequence": { "sequence": "MASCPDSDNSWVLAGSETLPVETLGPESRVDPESEEAPQALQDSSKADGKESAGTLNGEEMLFQTESSQGEGAALPEESEAKGALGGDDGHGTKRPGDTAVQEDLQETPMVTSLGPDTQDLERNIHPQNLPSSPRAVWKEHGCSSSDDDTDVDVEGLRRRRGREPSPPQPTAAVDGEDQAKGEGIGELGISLNMCFLGALVLLGLGILLFSGALLEPETEPVEEAELQVFPETELVQTVGNRQDEVEQLQASVPPDSVPSLQSMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLLHQPKGLEEENARLREALQQGKTSHQALESELQQLRARLQGLEANCVRGVDGVCLNWGGSPQGGKATTEQGHKGQEPDTSLLEQHKQLEAEAKALRQELQKQWQLLGSVHRNLQRGLQDAGQGAPAHAGLAELGHMLAQTLQGLESQGINTGRSSNDSEAWHQKKPRFQHPREWSGREKWRGGQRDQKAEHWKLKKEESGQDRKKSWRDEGREFTGHWKENRPRAEESGSRKDSKRQDPKVHPRKSGNSHSGERQKHSWGKDNSPDSVSWEELLRRKYRPPQGCSGVADCARQEGLALFGVELAPVRQQELASVLREYLARLPWAGQLTKELPLSPAYFGEDGIFRHDRLRFRDFVDALEDSLEEVALKQTGDDDEVDDFEDFIFSHFFGDKALKRRSKKKEKQPWNHRAVGPREEHSRHPHHYHQG", "length": 722, "header": "sp|A2VD12-1|PBIP1_RAT Isoform 1 of Pre-B-cell leukemia transcription factor-interacting protein 1 OS=Rattus norvegicus OX=10116 GN=Pbxip1 PE=1 SV=1 CANONICAL=A2VD12-1" }, "isoforms": [ { "isoform_ac": "A2VD12-1", "url": "https://www.uniprot.org/uniprot/A2VD12#A2VD12-1", "sequence": { "sequence": "MASCPDSDNSWVLAGSETLPVETLGPESRVDPESEEAPQALQDSSKADGKESAGTLNGEEMLFQTESSQGEGAALPEESEAKGALGGDDGHGTKRPGDTAVQEDLQETPMVTSLGPDTQDLERNIHPQNLPSSPRAVWKEHGCSSSDDDTDVDVEGLRRRRGREPSPPQPTAAVDGEDQAKGEGIGELGISLNMCFLGALVLLGLGILLFSGALLEPETEPVEEAELQVFPETELVQTVGNRQDEVEQLQASVPPDSVPSLQSMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLLHQPKGLEEENARLREALQQGKTSHQALESELQQLRARLQGLEANCVRGVDGVCLNWGGSPQGGKATTEQGHKGQEPDTSLLEQHKQLEAEAKALRQELQKQWQLLGSVHRNLQRGLQDAGQGAPAHAGLAELGHMLAQTLQGLESQGINTGRSSNDSEAWHQKKPRFQHPREWSGREKWRGGQRDQKAEHWKLKKEESGQDRKKSWRDEGREFTGHWKENRPRAEESGSRKDSKRQDPKVHPRKSGNSHSGERQKHSWGKDNSPDSVSWEELLRRKYRPPQGCSGVADCARQEGLALFGVELAPVRQQELASVLREYLARLPWAGQLTKELPLSPAYFGEDGIFRHDRLRFRDFVDALEDSLEEVALKQTGDDDEVDDFEDFIFSHFFGDKALKRRSKKKEKQPWNHRAVGPREEHSRHPHHYHQG", "length": 722, "header": "sp|A2VD12-1|PBIP1_RAT Isoform 1 of Pre-B-cell leukemia transcription factor-interacting protein 1 OS=Rattus norvegicus OX=10116 GN=Pbxip1 PE=1 SV=1 CANONICAL=A2VD12-1" }, "locus": { "chromosome": "2", "start_pos": 188775664, "end_pos": 188766570, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000028057", "url": "https://www.ensembl.org/id/ENSRNOT00000028057" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000028058", "url": "https://www.ensembl.org/id/ENSRNOP00000028058" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G09775CH", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "GlycoSuiteDB curation notes. Reported structure can be attached to the following: ASN-451 ; ASN-451", "start_pos": 451, "start_aa": "Asn", "end_pos": 451, "end_aa": "Asn", "residue": "Asn", "evidence": [ { "id": "A2VD12", "database": "UniCarbKB", "url": "http://unicarbkb.org/proteinsummary/A2VD12/annotated" }, { "id": "24090084", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24090084" } ] }, { "glytoucan_ac": "G31852PQ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "", "start_pos": 451, "start_aa": "Asn", "end_pos": 451, "end_aa": "Asn", "residue": "Asn", "evidence": [ { "id": "A2VD12", "database": "UniCarbKB", "url": "http://unicarbkb.org/proteinsummary/A2VD12/annotated" }, { "id": "24090084", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24090084" } ] }, { "glytoucan_ac": "G37135JQ", "type": "N-linked", "subtype": "", "site_category": "reported_with_glycan", "site_seq": "N", "relation": "attached", "comment": "ASN-451", "start_pos": 451, "start_aa": "Asn", "end_pos": 451, "end_aa": "Asn", "residue": "Asn", "evidence": [ { "id": "A2VD12", "database": "UniCarbKB", "url": "http://unicarbkb.org/proteinsummary/A2VD12/annotated" }, { "id": "24090084", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24090084" } ] } ], "phosphorylation": [ { "start_pos": 133, "end_pos": 133, "kinase_uniprot_canonical_ac": "Q703I1-1", "kinase_gene_name": "Oser1", "residue": "Ser", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" }, { "database": "iPTMnet", "id": "A2VD12", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2VD12" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] }, { "start_pos": 133, "end_pos": 133, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] }, { "start_pos": 144, "end_pos": 144, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ] }, { "start_pos": 145, "end_pos": 145, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ] }, { "start_pos": 146, "end_pos": 146, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ] }, { "start_pos": 150, "end_pos": 150, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ] }, { "start_pos": 166, "end_pos": 166, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ] }, { "start_pos": 559, "end_pos": 559, "kinase_uniprot_canonical_ac": "Q703I1-1", "kinase_gene_name": "Oser1", "residue": "Ser", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" }, { "database": "iPTMnet", "id": "A2VD12", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2VD12" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] }, { "start_pos": 559, "end_pos": 559, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nature communications", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" }, { "database": "iPTMnet", "id": "A2VD12", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2VD12" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] }, { "title": "Site-specific glycan-peptide analysis for determination of N-glycoproteome heterogeneity.", "journal": "Journal of proteome research", "date": "2013", "authors": "Parker BL, Thaysen-Andersen M, Solis N, Scott NE, Larsen MR, Graham ME, Packer NH, Cordwell SJ", "evidence": [ { "database": "UniCarbKB", "id": "A2VD12", "url": "http://unicarbkb.org/proteinsummary/A2VD12/annotated" } ], "reference": [ { "type": "PubMed", "id": "24090084", "url": "https://glygen.org/publication/PubMed/24090084" } ] } ], "pathway": [ { "id": "rno:310644", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:310644", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3TVI8-1", "protein_name": "Pre-B-cell leukemia transcription factor-interacting protein 1", "gene_name": "Pbxip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASCPDSDNSWVLAGSENLPVETLGPEPRMDPESEGASQALRDSSKADGKELAGTLDGEEKLFQTESSQRETAVLTESAAKGTLGADGHGTEAPGDTVVQEDSQETPVATSLGPDTQDLESEIHPQNLPSSPRAVWKEHRCSSSDDDTDVDVEGLRRRRGREPSSSQPVVPVDVEDQAKGEGIGGELGISLNMCFLGALVLLGLGILLFSGTLLEPETGPMEEAELQVFPETGPETELVETLGNRQDEIEHLQASSVPPDSVPSLQSMGFLLDKLAKENQDIRLLQAQLQAQKEELQSLLHQPKGLEEENARLREALQQGKTSHQALESELQQLRARLQGLEANCVRGVDGVCLNWGGDPQDGKATKEQGHKGQEPDPSLLEQHKQLEAEAKALRQELQRQWQLLGSVHWDLQRGLRDAGRGAPAHPGLAELGHMLAQTLQDLENQGINTGRSPNDSEAWHQKKPHTQSPREWGGKEKWRGGQRDQKAEHWKPRKEESGQERQRSWRDEGREHTGRWREDRLRADESGSRKDSKRQDPKVHPRKDGNSHSVERQKHSWGKDNSPDALSSWEELLRRKYRPPQGCSGVADCARQEGLALFGVELAPVRQQELASVLREYLSRLPWAGQLTKQLPLSPAYFGEDGIFRHDRLRFRDFVDALEDSLEEVALKQTGDDDEVDDFEDFVFGHFFGDKALKKRSRKKEKHSWNPRVVGPREEHSRHPHHYHQG", "length": 727 }, "evidence": [ { "id": "10740", "url": "http://www.informatics.jax.org/homology/10740", "database": "MGI" }, { "id": "A2VD12", "url": "https://omabrowser.org/oma/group/A2VD12/", "database": "OMA" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AQ6-1", "protein_name": "Pre-B-cell leukemia transcription factor-interacting protein 1", "gene_name": "PBXIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASCPDSDNSWVLAGSESLPVETLGPASRMDPESERALQAPHSPSKTDGKELAGTMDGEGTLFQTESPQSGSILTEETEVKGTLEGDVCGVEPPGPGDTVVQGDLQETTVVTGLGPDTQDLEGQSPPQSLPSTPKAAWIREEGRCSSSDDDTDVDMEGLRRRRGREAGPPQPMVPLAVENQAGGEGAGGELGISLNMCLLGALVLLGLGVLLFSGGLSESETGPMEEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAELLRPKYRAPQGCSGVDECARQEGLTFFGTELAPVRQQELASLLRTYLARLPWAGQLTKELPLSPAFFGEDGIFRHDRLRFRDFVDALEDSLEEVAVQQTGDDDEVDDFEDFIFSHFFGDKALKKRSGKKDKHSQSPRAAGPREGHSHSHHHHHRG", "length": 731 }, "evidence": [ { "id": "10740", "url": "http://www.informatics.jax.org/homology/10740", "database": "MGI" }, { "id": "A2VD12", "url": "https://omabrowser.org/oma/group/A2VD12/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "21873635" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "extracellular matrix disassembly", "id": "GO:0022617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022617", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "positive regulation of transcription, DNA-templated", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "regulation of Rho guanyl-nucleotide exchange factor activity", "id": "GO:2001106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001106", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "21873635" }, { "name": "production of molecular mediator involved in inflammatory response", "id": "GO:0002532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002532", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "positive regulation of chondrocyte proliferation", "id": "GO:1902732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902732", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "gene expression involved in extracellular matrix organization", "id": "GO:1901148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901148", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway", "id": "GO:0030177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030177", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "articular cartilage development", "id": "GO:0061975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061975", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "histone H3-K56 acetylation", "id": "GO:0097043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097043", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A2VD12", "url": "https://www.uniprot.org/uniprot/A2VD12" } ], "pmid": "" } ] } ] }, "pro_annotation": [ { "name": "pre-B-cell leukemia transcription factor-interacting protein 1 N-glycosylated 1 (rat)", "definition": "A pre-B-cell leukemia transcription factor-interacting protein 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-451 of the amino acid sequence represented by UniProtKB:A2VD12-1, in which the glycan structure is represented by GlyTouCan:G09775CH. Example: UniProtKB:A2VD12-1, Asn-451, MOD:00160~GNO:G09775CH. [PRO:DNx, PMID:24090084]", "evidence": [ { "id": "PR:000058538", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000058538" } ] }, { "name": "pre-B-cell leukemia transcription factor-interacting protein 1 N-glycosylated 2 (rat)", "definition": "A pre-B-cell leukemia transcription factor-interacting protein 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-451 of the amino acid sequence represented by UniProtKB:A2VD12-1, in which the glycan composition is represented by GlyTouCan:G31852PQ. Example: UniProtKB:A2VD12-1, Asn-451, MOD:00160~GNO:G31852PQ. [PRO:DNx, PMID:24090084]", "evidence": [ { "id": "PR:000058539", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000058539" } ] }, { "name": "pre-B-cell leukemia transcription factor-interacting protein 1 N-glycosylated 3 (rat)", "definition": "A pre-B-cell leukemia transcription factor-interacting protein 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-451 of the amino acid sequence represented by UniProtKB:A2VD12-1, in which the glycan structure is represented by GlyTouCan:G37135JQ. Example: UniProtKB:A2VD12-1, Asn-451, MOD:00160~GNO:G37135JQ. [PRO:DNx, PMID:24090084]", "evidence": [ { "id": "PR:000058540", "database": "PRO", "url": "https://proconsortium.org/app/entry/PR:000058540" } ] } ], "site_annotation": [ { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ] }