{
    "uniprot_canonical_ac": "A2VCW5-1",
    "uniprot_ac": "A2VCW5",
    "uniprot_id": "S38A5_RAT",
    "mass": {
        "chemical_mass": 52436.0,
        "monoisotopic_mass": 52436.0
    },
    "refseq": {
        "ac": "XP_008771290",
        "name": "sodium-coupled neutral amino acid transporter 5 isoform X1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008771290"
    },
    "gene_names": [
        {
            "name": "Slc38a5",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2VCW5",
            "id": "A2VCW5"
        },
        {
            "name": "SN2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008771290",
            "id": "XP_008771290"
        },
        {
            "name": "Slc38a5",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008771290",
            "id": "XP_008771290"
        },
        {
            "name": "Sn2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2VCW5",
            "id": "A2VCW5"
        },
        {
            "name": "Snat5",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2VCW5",
            "id": "A2VCW5"
        }
    ],
    "protein_names": [
        {
            "name": "Sodium-coupled neutral amino acid transporter 5",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2VCW5#names_and_taxonomy",
            "id": "A2VCW5"
        },
        {
            "name": "Solute carrier family 38 member 5",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2VCW5#names_and_taxonomy",
            "id": "A2VCW5"
        },
        {
            "name": "System N transporter 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2VCW5#names_and_taxonomy",
            "id": "A2VCW5"
        },
        {
            "name": "sodium-coupled neutral amino acid transporter 5 isoform X1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008771290",
            "id": "XP_008771290"
        },
        {
            "name": "sodium-coupled neutral amino acid transporter 5",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209",
            "id": "NP_620209"
        },
        {
            "name": "system N transporter 2; amino acid transporter system N2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209",
            "id": "NP_620209"
        }
    ],
    "function": [
        {
            "annotation": "Functions as a sodium-dependent amino acid transporter which countertransport protons. Mediates the saturable, pH-sensitive, and electrogenic cotransport of several neutral amino acids including glycine, asparagine, alanine, serine, glutamine and histidine with sodium.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2VCW5",
                    "url": "https://www.uniprot.org/uniprot/A2VCW5#function"
                },
                {
                    "database": "PubMed",
                    "id": "16629640",
                    "url": "https://glygen.org/publication/PubMed/16629640"
                },
                {
                    "database": "PubMed",
                    "id": "11698233",
                    "url": "https://glygen.org/publication/PubMed/11698233"
                }
            ]
        },
        {
            "annotation": "PH-sensitive System A (SNAT2) and System N (SNAT5) amino acid transporter activity allosteric regulation involves a conserved histidine residue",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_620209",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209"
                },
                {
                    "database": "PubMed",
                    "id": "16629640",
                    "url": "https://glygen.org/publication/PubMed/16629640"
                }
            ]
        },
        {
            "annotation": "SN2 doubles as a transmitter precursor furnisher and a potential regulator of NMDA receptors.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_620209",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209"
                },
                {
                    "database": "PubMed",
                    "id": "22821889",
                    "url": "https://glygen.org/publication/PubMed/22821889"
                }
            ]
        },
        {
            "annotation": "SNAT5/SN2 expression is coordinated with that of other proteins necessary for the operation of glutamatergic synapses",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_620209",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209"
                },
                {
                    "database": "PubMed",
                    "id": "24333324",
                    "url": "https://glygen.org/publication/PubMed/24333324"
                }
            ]
        },
        {
            "annotation": "The effect of lipopolysaccharides on system N expression occurs not only at the protein level, but also at the mRNA level",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_620209",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209"
                },
                {
                    "database": "PubMed",
                    "id": "20036385",
                    "url": "https://glygen.org/publication/PubMed/20036385"
                }
            ]
        },
        {
            "annotation": "This transporter is likely to be involved in glutamatergic pathways in the brain.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_620209",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209"
                },
                {
                    "database": "PubMed",
                    "id": "15390093",
                    "url": "https://glygen.org/publication/PubMed/15390093"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [
        {
            "start_pos": 479,
            "end_pos": 479,
            "sequence_org": "H",
            "sequence_mut": "A",
            "comment": "Modifies the transporter pH-sensitivity.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2VCW5",
                    "url": "https://www.uniprot.org/uniprot/A2VCW5"
                },
                {
                    "database": "PubMed",
                    "id": "16629640",
                    "url": "https://glygen.org/publication/PubMed/16629640"
                }
            ]
        }
    ],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2VCW5",
                    "url": "https://www.uniprot.org/uniprot/A2VCW5"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Slc38a5",
            "url": "https://www.uniprot.org/uniprot/A2VCW5",
            "locus": {
                "chromosome": "X",
                "start_pos": 14972675,
                "end_pos": 14963921,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000027767",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000027767"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000027767",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000027767",
            "database": "Bgee"
        },
        {
            "id": "192208",
            "url": "https://www.ncbi.nlm.nih.gov/gene/192208",
            "database": "GeneID"
        },
        {
            "id": "IPR013057",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057",
            "database": "InterPro"
        },
        {
            "id": "rno:192208",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:192208",
            "database": "KEGG Pathway"
        },
        {
            "id": "VGMELQD",
            "url": "https://omabrowser.org/oma/group/VGMELQD/",
            "database": "OMA"
        },
        {
            "id": "697331at2759",
            "url": "http://www.orthodb.org/?query=697331at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PF01490",
            "url": "http://pfam.xfam.org/family/PF01490",
            "database": "Pfam"
        },
        {
            "id": "PR_A2VCW5",
            "url": "http://purl.obolibrary.org/obo/PR_A2VCW5",
            "database": "PRO"
        },
        {
            "id": "R-RNO-352230",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-352230",
            "database": "Reactome"
        },
        {
            "id": "NP_620209",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209",
            "database": "RefSeq"
        },
        {
            "id": "XP_008771290",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008771290",
            "database": "RefSeq"
        },
        {
            "id": "620702",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=620702",
            "database": "RGD"
        },
        {
            "id": "A0A0H2UHW1",
            "url": "https://www.uniprot.org/uniprot/A0A0H2UHW1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A0H2UHW1-1",
            "url": "https://www.uniprot.org/uniprot/A0A0H2UHW1-1",
            "database": "UniProtKB"
        },
        {
            "id": "A2VCW5",
            "url": "https://www.uniprot.org/uniprot/A2VCW5",
            "database": "UniProtKB"
        },
        {
            "id": "A2VCW5-1",
            "url": "https://www.uniprot.org/uniprot/A2VCW5-1",
            "database": "UniProtKB"
        },
        {
            "id": "A2VCW5-2",
            "url": "https://www.uniprot.org/uniprot/A2VCW5-2",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MAISCAVGMEMQEPKMNGTLSTGAAAGYRQEREGFLPTTHGPAPGRKPVQFLDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCASVVGIRAYEQLGQRAFGPAGKVVVAIIICLHNVGAMSSYLFIIKSELPLVIGTFLHMDPEGDWFLKGNLLIILVSLLIILPLALMKHLGYLGYTSSLSLTCMLFFLISVIYKKFQLGCVVSHNDTVVESEPAPLQAFNSSCEAKLFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCCPTQRRMQAVANMSIGAMFIMYGLTATFGYLTFYSTVKAEMLEMYTQEDLLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPSKAFSWPRHVAIALILLILVNILVICVPTIRDIFGFIGSTSAPSLIFILPSVFYLRIVPADMEPLFSWPKIQALCFGVLGVLFMAISLGFMFANWATGQSRMSGH",
        "length": 479,
        "header": "sp|A2VCW5-1|S38A5_RAT Isoform 1 of Sodium-coupled neutral amino acid transporter 5  OS=Rattus norvegicus OX=10116 GN=Slc38a5 PE=1 SV=1 CANONICAL=A2VCW5-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0H2UHW1-1",
            "url": "https://www.uniprot.org/uniprot/A2VCW5#A0A0H2UHW1-1",
            "sequence": {
                "sequence": "MAISGAVGMEMQEPKMNGTLSTGAAAGYRQEREGFLPTTHGPAPGRKPVQFLDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCASVVGIRAYEQLGQRAFGPAGKVVVAIIICLHNVGAMSSYLFIIKSELPLVIGTFLHMDPEGDWFLKGNLLIILVSLLIILPLALMKHLGYLGYTSSLSLTCMLFFLISVIYKKFQLGCVVSHNDTVVESEPAPLQAFNSSCEAKLFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCCPTQRRMQAVANMSIGAMFIMYGLTATFGYLTFYSTVKAEMLEMYTQEDLLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPSKAFSWPRHVAIALILLILVNILVICVPTIRDIFGFIGSTSAPSLIFILPSVFYLRIVPADMEPLFSWPKIQALCFGVLGVLFMAISLGFMFANWATGQSRMSGH",
                "length": 479,
                "header": "tr|A0A0H2UHW1-1|S38A5_RAT Computationally mapped isoform of Sodium-coupled neutral amino acid transporter 5  OS=Rattus norvegicus OX=10116 GN=Slc38a5 PE=1 SV=1 CANONICAL=A2VCW5-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 14972366,
                "end_pos": 14964248,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000038068",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000038068"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000038781",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000038781"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2VCW5-1",
            "url": "https://www.uniprot.org/uniprot/A2VCW5#A2VCW5-1",
            "sequence": {
                "sequence": "MAISCAVGMEMQEPKMNGTLSTGAAAGYRQEREGFLPTTHGPAPGRKPVQFLDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCASVVGIRAYEQLGQRAFGPAGKVVVAIIICLHNVGAMSSYLFIIKSELPLVIGTFLHMDPEGDWFLKGNLLIILVSLLIILPLALMKHLGYLGYTSSLSLTCMLFFLISVIYKKFQLGCVVSHNDTVVESEPAPLQAFNSSCEAKLFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCCPTQRRMQAVANMSIGAMFIMYGLTATFGYLTFYSTVKAEMLEMYTQEDLLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPSKAFSWPRHVAIALILLILVNILVICVPTIRDIFGFIGSTSAPSLIFILPSVFYLRIVPADMEPLFSWPKIQALCFGVLGVLFMAISLGFMFANWATGQSRMSGH",
                "length": 479,
                "header": "sp|A2VCW5-1|S38A5_RAT Isoform 1 of Sodium-coupled neutral amino acid transporter 5  OS=Rattus norvegicus OX=10116 GN=Slc38a5 PE=1 SV=1 CANONICAL=A2VCW5-1"
            },
            "locus": {}
        },
        {
            "isoform_ac": "A2VCW5-2",
            "url": "https://www.uniprot.org/uniprot/A2VCW5#A2VCW5-2",
            "sequence": {
                "sequence": "MEMQEPKMNGTLSTGAAAGYRQEREGFLPTTHGPAPGRKPVQFLDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCASVVGIRAYEQLGQRAFGPAGKVVVAIIICLHNVGAMSSYLFIIKSELPLVIGTFLHMDPEGDWFLKGNLLIILVSLLIILPLALMKHLGYLGYTSSLSLTCMLFFLISVIYKKFQLGCVVSHNDTVVESEPAPLQAFNSSCEAKLFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCCPTQRRMQAVANMSIGAMFIMYGLTATFGYLTFYSTVKAEMLEMYTQEDLLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPSKAFSWPRHVAIALILLILVNILVICVPTIRDIFGFIGSTSAPSLIFILPSVFYLRIVPADMEPLFSWPKIQALCFGVLGVLFMAISLGFMFANWATGQSRMSGH",
                "length": 471,
                "header": "sp|A2VCW5-2|S38A5_RAT Isoform 2 of Sodium-coupled neutral amino acid transporter 5  OS=Rattus norvegicus OX=10116 GN=Slc38a5 PE=1 SV=1 CANONICAL=A2VCW5-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 14972000,
                "end_pos": 14964248,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000079664",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000079664"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000073818",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000073818"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 236,
            "start_aa": "Asn",
            "end_pos": 236,
            "end_aa": "Asn",
            "residue": "Asn",
            "evidence": [
                {
                    "id": "A2VCW5",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/A2VCW5#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "Cloning and functional characterization of a new subtype of the amino acid transport system N.",
            "journal": "Am. J. Physiol.",
            "date": "2001",
            "authors": "Sugawara M., Ganapathy V., Kekuda R., Leibach F.H., Prasad P.D., Nakanishi T., Fei Y.J., Hatanaka T., Martindale R.G.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2VCW5",
                    "url": "https://www.uniprot.org/uniprot/A2VCW5"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11698233",
                    "url": "https://glygen.org/publication/PubMed/11698233"
                }
            ]
        },
        {
            "title": "Amino acid transporter SNAT5 localizes to glial cells in the rat brain.",
            "journal": "Glia",
            "date": "2005",
            "authors": "Cubelos B., Gimenez C., Gonzalez-Gonzalez I.M., Zafra F.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2VCW5",
                    "url": "https://www.uniprot.org/uniprot/A2VCW5"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_620209",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15390093",
                    "url": "https://glygen.org/publication/PubMed/15390093"
                }
            ]
        },
        {
            "title": "Evidence for allosteric regulation of pH-sensitive System A (SNAT2) and System N (SNAT5) amino acid transporter activity involving a conserved histidine residue.",
            "journal": "Biochem. J.",
            "date": "2006",
            "authors": "Ganapathy V., Taylor P.M., Hundal H.S., Pinilla-Tenas J.J., Baird F.E., Ogilvie W.L.J.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2VCW5",
                    "url": "https://www.uniprot.org/uniprot/A2VCW5"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_620209",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "16629640",
                    "url": "https://glygen.org/publication/PubMed/16629640"
                }
            ]
        },
        {
            "title": "Changes of plasma glutamine concentration and hepatocyte membrane system N transporters expression in early endotoxemia.",
            "journal": "The Journal of surgical research",
            "date": "2011",
            "authors": "Wang W, Li Y, Zhang W, Zhang F, Li J",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_620209",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "20036385",
                    "url": "https://glygen.org/publication/PubMed/20036385"
                }
            ]
        },
        {
            "title": "The system N transporter SN2 doubles as a transmitter precursor furnisher and a potential regulator of NMDA receptors.",
            "journal": "Glia",
            "date": "2012",
            "authors": "Hamdani el H, Gudbrandsen M, Bjorkmo M, Chaudhry FA",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_620209",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "22821889",
                    "url": "https://glygen.org/publication/PubMed/22821889"
                }
            ]
        },
        {
            "title": "Expression of the System N transporter (SNAT5/SN2) during development indicates its plausible role in glutamatergic neurotransmission.",
            "journal": "Neurochemistry international",
            "date": "2014",
            "authors": "Rodriguez A, Ortega A, Berumen LC, Garcia-Alcocer MG, Gimenez C, Zafra F",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_620209",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_620209"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "24333324",
                    "url": "https://glygen.org/publication/PubMed/24333324"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:192208",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:192208",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-352230",
            "name": "Amino acid transport across the plasma membrane",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-352230",
            "resource": "Reactome",
            "description": "Amino acid transport across the plasma membrane"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q3U1J0-1",
            "protein_name": "Sodium-coupled neutral amino acid transporter 5",
            "gene_name": "Slc38a5",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MAISCAVGMEMQEPKMNGTLSAGAAAGYRQEREGFLPTTRNPATGRKPVQFLDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCASVVGIRAYEQLGQRAFGPAGKVVVAIIICLHNVGAMSSYLFIIKSELPLVIGTFLHMDPEGDWFLKGNLLIILVSLLIILPLALMKHLGYLGYTSSLSLTCMLFFLISVIYKKFQIGCDVSHNDTVVEAEQAPLQAFNSSCEAELFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPTQRRMQAVANMSIGAMFIMYGLTATFGYLTFYSTVKAEMLEMYTQEDMLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPSKAFSWLRHVAIALILLILVNILVICVPTIRDIFGFIGSTSAPSLIFILPSVFYLRIVPTEVEPLFSWPKIQALCFGVLGVLFMAISLGFMFANWATGQSRMSGH",
                "length": 479
            },
            "evidence": [
                {
                    "id": "24917",
                    "url": "http://www.informatics.jax.org/homology/24917",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q8WUX1-1",
            "protein_name": "Sodium-coupled neutral amino acid transporter 5",
            "gene_name": "SLC38A5",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MELQDPKMNGALPSDAVGYRQEREGFLPSRGPAPGSKPVQFMDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANWATGQSRMSGH",
                "length": 472
            },
            "evidence": [
                {
                    "id": "24917",
                    "url": "http://www.informatics.jax.org/homology/24917",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 9,
                "go_terms": [
                    {
                        "name": "glycine transmembrane transporter activity",
                        "id": "GO:0015187",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015187",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "L-glutamine transmembrane transporter activity",
                        "id": "GO:0015186",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015186",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "L-histidine transmembrane transporter activity",
                        "id": "GO:0005290",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005290",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "L-asparagine transmembrane transporter activity",
                        "id": "GO:0015182",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015182",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "serine transmembrane transporter activity",
                        "id": "GO:0022889",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022889",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "alanine transmembrane transporter activity",
                        "id": "GO:0022858",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022858",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "amino acid transmembrane transporter activity",
                        "id": "GO:0015171",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": "11698233"
                    },
                    {
                        "name": "neutral amino acid transmembrane transporter activity",
                        "id": "GO:0015175",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015175",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": "11698233"
                    },
                    {
                        "name": "L-serine transmembrane transporter activity",
                        "id": "GO:0015194",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015194",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": "15218073"
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 9,
                "go_terms": [
                    {
                        "name": "asparagine transmembrane transport",
                        "id": "GO:1903713",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903713",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "L-alanine transmembrane transport",
                        "id": "GO:1904557",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904557",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glycine transport",
                        "id": "GO:0015816",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015816",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": "11698233"
                    },
                    {
                        "name": "serine transport",
                        "id": "GO:0032329",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032329",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "L-serine transport",
                        "id": "GO:0015825",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015825",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": "15218073"
                    },
                    {
                        "name": "neutral amino acid transport",
                        "id": "GO:0015804",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015804",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": "11698233"
                    },
                    {
                        "name": "glutamine transport",
                        "id": "GO:0006868",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006868",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": "15218073"
                    },
                    {
                        "name": "amino acid transmembrane transport",
                        "id": "GO:0003333",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "L-histidine transmembrane transport",
                        "id": "GO:0089709",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089709",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": "15218073"
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "integral component of membrane",
                        "id": "GO:0016021",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "integral component of plasma membrane",
                        "id": "GO:0005887",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005887",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2VCW5",
                                "url": "https://www.uniprot.org/uniprot/A2VCW5"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 17,
            "end_pos": 19,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 236,
            "end_pos": 238,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 251,
            "end_pos": 253,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 302,
            "end_pos": 304,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 66,
            "end_pos": 68,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}