{ "uniprot_canonical_ac": "A2BH40-1", "uniprot_ac": "A2BH40", "uniprot_id": "ARI1A_MOUSE", "mass": { "chemical_mass": 242092.0, "monoisotopic_mass": 242092.0 }, "refseq": { "ac": "NP_001074288", "name": "AT-rich interactive domain-containing protein 1A isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288" }, "gene_names": [ { "name": "Arid1a", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2BH40", "id": "A2BH40" }, { "name": "1110030E03Rik; BAF250; BAF250a; Osa1; Smarcf1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288", "id": "NP_001074288" }, { "name": "Arid1a", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288", "id": "NP_001074288" }, { "name": "Baf250a", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40", "id": "A2BH40" }, { "name": "Baf250", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40", "id": "A2BH40" }, { "name": "Osa1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40", "id": "A2BH40" }, { "name": "Smarcf1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40", "id": "A2BH40" } ], "protein_names": [ { "name": "AT-rich interactive domain-containing protein 1A", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2BH40#names_and_taxonomy", "id": "A2BH40" }, { "name": "ARID domain-containing protein 1A", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40#names_and_taxonomy", "id": "A2BH40" }, { "name": "AT rich interactive domain 1A (Swi1 like); AT-rich interactive domain-containing protein 1A; osa homolog 1; SWI-like protein; BRG1-associated factor 250a; ARID domain-containing protein 1A; SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1; SWI/SNF complex protein p270", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288", "id": "NP_001074288" }, { "name": "AT-rich interactive domain-containing protein 1A isoform 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288", "id": "NP_001074288" }, { "name": "BAF250A", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40#names_and_taxonomy", "id": "A2BH40" }, { "name": "BAF250", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40#names_and_taxonomy", "id": "A2BH40" }, { "name": "BRG1-associated factor 250a", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40#names_and_taxonomy", "id": "A2BH40" }, { "name": "BRG1-associated factor 250", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40#names_and_taxonomy", "id": "A2BH40" }, { "name": "Osa homolog 1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40#names_and_taxonomy", "id": "A2BH40" }, { "name": "SWI-like protein", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40#names_and_taxonomy", "id": "A2BH40" }, { "name": "SWI/SNF complex protein p270", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40#names_and_taxonomy", "id": "A2BH40" }, { "name": "SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2BH40#names_and_taxonomy", "id": "A2BH40" } ], "function": [ { "annotation": "Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription.", "evidence": [ { "database": "RefSeq", "id": "NP_001074288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288" }, { "database": "PubMed", "id": "34731603", "url": "https://glygen.org/publication/PubMed/34731603" } ] }, { "annotation": "Arid1a regulates neural stem/progenitor cell proliferation and differentiation during cortical development.", "evidence": [ { "database": "RefSeq", "id": "NP_001074288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288" }, { "database": "PubMed", "id": "34562292", "url": "https://glygen.org/publication/PubMed/34562292" } ] }, { "annotation": "Chromatin remodeler ARID1A binds IRF3 to selectively induce antiviral interferon production in macrophages. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001074288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288" }, { "database": "PubMed", "id": "34315861", "url": "https://glygen.org/publication/PubMed/34315861" } ] }, { "annotation": "Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically (PubMed:22952240, PubMed:26601204). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (PubMed:17640523).", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40#function" }, { "database": "PubMed", "id": "26601204", "url": "https://glygen.org/publication/PubMed/26601204" }, { "database": "PubMed", "id": "17640523", "url": "https://glygen.org/publication/PubMed/17640523" }, { "database": "PubMed", "id": "22952240", "url": "https://glygen.org/publication/PubMed/22952240" }, { "database": "PubMed", "id": "O14497", "url": "https://glygen.org/publication/PubMed/O14497" } ] }, { "annotation": "Results provide a direct biological basis to support the implication from tumor tissue screens that deficiency of p270 plays a causative role in carcinogenesis.", "evidence": [ { "database": "RefSeq", "id": "NP_001074288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288" }, { "database": "PubMed", "id": "16230384", "url": "https://glygen.org/publication/PubMed/16230384" } ] } ], "disease": [ { "disease_id": "DOID:0070044", "recommended_name": { "id": "DOID:0070044", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0070044", "name": "Coffin-Siris syndrome 2", "description": "A Coffin-Siris syndrome that has_material_basis_in an autosomal dominant mutation of ARID1A on chromosome 1p36.11." }, "synonyms": [ { "id": "DOID:0070044", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0070044", "name": "CSS2", "description": "" }, { "id": "DOID:0070044", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0070044", "name": "MRD14", "description": "" }, { "id": "DOID:0070044", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0070044", "name": "autosomal dominant mental retardation 14", "description": "" }, { "id": "MONDO:0013819", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013819", "name": "intellectual disability, autosomal dominant 14", "description": "Any Coffin-Siris syndrome in which the cause of the disease is a mutation in the ARID1A gene." }, { "id": "MONDO:0013819", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013819", "name": "CSS2", "description": "" }, { "id": "MONDO:0013819", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013819", "name": "ARID1A Coffin-Siris syndrome", "description": "" }, { "id": "MONDO:0013819", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013819", "name": "COFFIN-SIRIS syndrome 2; CSS2", "description": "" }, { "id": "MONDO:0013819", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013819", "name": "mental retardation, autosomal dominant 14; MRD14", "description": "" }, { "id": "MONDO:0013819", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013819", "name": "MRD14", "description": "" }, { "id": "MONDO:0013819", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013819", "name": "Coffin-Siris syndrome caused by mutation in ARID1A", "description": "" }, { "id": "MONDO:0013819", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013819", "name": "mental retardation, autosomal dominant 14", "description": "" }, { "id": "MONDO:0013819", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013819", "name": "autosomal dominant mental retardation 14", "description": "" }, { "id": "MONDO:0013819", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013819", "name": "Coffin-Siris syndrome 2", "description": "" }, { "id": "MONDO:0013819", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013819", "name": "mental retardation, autosomal dominant type 14", "description": "" }, { "id": "MIM:614607", "resource": "MIM", "url": "https://www.omim.org/entry/614607", "name": "Coffin-Siris syndrome 2", "description": "Coffin-Siris syndrome 2" } ], "evidence": [ { "id": "0070044", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0070044" } ] }, { "disease_id": "DOID:1925", "recommended_name": { "id": "DOID:1925", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1925", "name": "Coffin-Siris syndrome", "description": "An autosomal dominant non-syndromic intellectual disability that is characterized by mental retardation associated with coarse facial features, hypertrichosis, sparse scalp hair, and hypoplastic or absent fifth fingernails or toenails." }, "synonyms": [ { "id": "DOID:1925", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1925", "name": "Dwarfism-Onychodysplasia", "description": "" }, { "id": "DOID:1925", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1925", "name": "Fifth Digit Syndrome", "description": "" }, { "id": "DOID:1925", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1925", "name": "Short Stature-Onychodysplasia.", "description": "" }, { "id": "MONDO:0007617", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007617", "name": "Coffin-Siris syndrome 1", "description": "" }, { "id": "MONDO:0007617", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007617", "name": "CSS", "description": "" }, { "id": "MONDO:0007617", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007617", "name": "fifth digit syndrome", "description": "" }, { "id": "MONDO:0007617", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007617", "name": "COFFIN-SIRIS syndrome 1; CSS1", "description": "" }, { "id": "MONDO:0007617", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007617", "name": "COFFIN-SIRIS syndrome; CSS", "description": "" }, { "id": "MONDO:0007617", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007617", "name": "COFFIN-SIRIS syndrome", "description": "" }, { "id": "MIM:135900", "resource": "MIM", "url": "https://www.omim.org/entry/135900", "name": "Coffin-Siris syndrome 1", "description": "Coffin-Siris syndrome 1" } ], "evidence": [ { "id": "1925", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:1925" } ] }, { "disease_id": "DOID:4928", "recommended_name": { "id": "DOID:4928", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:4928", "name": "intrahepatic cholangiocarcinoma", "description": "" }, "synonyms": [ { "id": "DOID:4928", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:4928", "name": "Intrahepatic bile duct carcinoma", "description": "" }, { "id": "DOID:4928", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:4928", "name": "peripheral Cholangiocarcinoma", "description": "" } ], "evidence": [ { "id": "4928", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:4928" } ] }, { "disease_id": "DOID:769", "recommended_name": { "id": "DOID:769", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:769", "name": "neuroblastoma", "description": "An autonomic nervous system neoplasm that derives_from immature nerve cells." }, "synonyms": [], "evidence": [ { "id": "769", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:769" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Arid1a", "url": "https://www.uniprot.org/uniprot/A2BH40", "locus": { "chromosome": "4", "start_pos": 133756769, "end_pos": 133679008, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000007880", "url": "https://www.ensembl.org/id/ENSMUSG00000007880" } ] } } ], "crossref": [ { "id": "ENSMUSG00000007880", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000007880", "database": "Bgee" }, { "id": "93760", "url": "https://www.ncbi.nlm.nih.gov/gene/93760", "database": "GeneID" }, { "id": "A2BH40", "url": "https://www.ebi.ac.uk/intact/interactors/id:A2BH40*", "database": "IntAct" }, { "id": "E9QAQ7", "url": "https://www.ebi.ac.uk/intact/interactors/id:E9QAQ7*", "database": "IntAct" }, { "id": "IPR001606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001606", "database": "InterPro" }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro" }, { "id": "IPR021906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021906", "database": "InterPro" }, { "id": "IPR030094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030094", "database": "InterPro" }, { "id": "IPR033388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033388", "database": "InterPro" }, { "id": "IPR036431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036431", "database": "InterPro" }, { "id": "mmu:93760", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:93760", "database": "KEGG Pathway" }, { "id": "1935147", "url": "http://www.informatics.jax.org/marker/MGI:1935147", "database": "MGI" }, { "id": "WAQMNAG", "url": "https://omabrowser.org/oma/group/WAQMNAG/", "database": "OMA" }, { "id": "256110at2759", "url": "http://www.orthodb.org/?query=256110at2759", "database": "OrthoDB" }, { "id": "PTHR12656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12656", "database": "PANTHER" }, { "id": "PTHR12656:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12656:SF12", "database": "PANTHER" }, { "id": "PF01388", "url": "http://pfam.xfam.org/family/PF01388", "database": "Pfam" }, { "id": "PF12031", "url": "http://pfam.xfam.org/family/PF12031", "database": "Pfam" }, { "id": "PR_A2BH40", "url": "http://purl.obolibrary.org/obo/PR_A2BH40", "database": "PRO" }, { "id": "R-MMU-3214858", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3214858", "database": "Reactome" }, { "id": "R-MMU-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8939243", "database": "Reactome" }, { "id": "NP_001074288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288", "database": "RefSeq" }, { "id": "XP_006539389", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006539389", "database": "RefSeq" }, { "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40", "database": "UniProtKB" }, { "id": "A2BH40-1", "url": "https://www.uniprot.org/uniprot/A2BH40-1", "database": "UniProtKB" }, { "id": "A2BH40-2", "url": "https://www.uniprot.org/uniprot/A2BH40-2", "database": "UniProtKB" }, { "id": "A2BH40-3", "url": "https://www.uniprot.org/uniprot/A2BH40-3", "database": "UniProtKB" }, { "id": "A2BH40-4", "url": "https://www.uniprot.org/uniprot/A2BH40-4", "database": "UniProtKB" }, { "id": "E9Q495", "url": "https://www.uniprot.org/uniprot/E9Q495", "database": "UniProtKB" }, { "id": "E9Q495-1", "url": "https://www.uniprot.org/uniprot/E9Q495-1", "database": "UniProtKB" }, { "id": "E9QAQ7", "url": "https://www.uniprot.org/uniprot/E9QAQ7", "database": "UniProtKB" }, { "id": "E9QAQ7-1", "url": "https://www.uniprot.org/uniprot/E9QAQ7-1", "database": "UniProtKB" } ], "sequence": { "sequence": "MAAQVAPAAASSLGNPPPPPSELKKAEQQQREEAGGEAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLPEPPGGGGGGGSSSSDGVGAPPHSAAAALPPPAYGFGQAYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPPQAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYGGGPQDGGAGKGPADMASQCWGAAAAAAAAAAAVSGGAQQRSHHAPMSPGSSGGGGQPLARTPQSSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGSLSYAQQIPPYGQQGPSAYGQQGQTPYYNQQSPHPQQQPPYAQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQPPHQQSPTPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPASSSLSQQAAYPQPQPQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHSGVGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPNAGMAGSMNPMGAGGQMHGQPGIPPYGTLPPGRMAHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQESAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFPDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGSVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTPDSGMYSPSRYPPQQQQQQQQQHDSYGNQFSTQGTPSSSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSAGQGQPQQQQLPAAQSQPASQPQAAQPSPQQDVYNQYSNAYPASATAATDRRPAGGPQNQFPFQFGRDRVSAPPGSSAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQNTGSATQGPAYHGVNRTDEMLHTDQRANHEGPWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMPNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPTPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFTKVYSPAHTEEEEEEHLDPKLEEEEEEGVGNDEEMAFLGKDKPSSENNEEKLVSKFDKLPVKIVQRNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKIELLPSRPYVPCPTPPRKHLTTVEGTPGTTEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGAKSAEATKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCDKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2283, "header": "sp|A2BH40-1|ARI1A_MOUSE Isoform 1 of AT-rich interactive domain-containing protein 1A OS=Mus musculus OX=10090 GN=Arid1a PE=1 SV=1 CANONICAL=A2BH40-1" }, "isoforms": [ { "isoform_ac": "A2BH40-1", "url": "https://www.uniprot.org/uniprot/A2BH40#A2BH40-1", "sequence": { "sequence": "MAAQVAPAAASSLGNPPPPPSELKKAEQQQREEAGGEAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLPEPPGGGGGGGSSSSDGVGAPPHSAAAALPPPAYGFGQAYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPPQAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYGGGPQDGGAGKGPADMASQCWGAAAAAAAAAAAVSGGAQQRSHHAPMSPGSSGGGGQPLARTPQSSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGSLSYAQQIPPYGQQGPSAYGQQGQTPYYNQQSPHPQQQPPYAQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQPPHQQSPTPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPASSSLSQQAAYPQPQPQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHSGVGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPNAGMAGSMNPMGAGGQMHGQPGIPPYGTLPPGRMAHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQESAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFPDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGSVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTPDSGMYSPSRYPPQQQQQQQQQHDSYGNQFSTQGTPSSSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSAGQGQPQQQQLPAAQSQPASQPQAAQPSPQQDVYNQYSNAYPASATAATDRRPAGGPQNQFPFQFGRDRVSAPPGSSAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQNTGSATQGPAYHGVNRTDEMLHTDQRANHEGPWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMPNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPTPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFTKVYSPAHTEEEEEEHLDPKLEEEEEEGVGNDEEMAFLGKDKPSSENNEEKLVSKFDKLPVKIVQRNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKIELLPSRPYVPCPTPPRKHLTTVEGTPGTTEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGAKSAEATKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCDKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2283, "header": "sp|A2BH40-1|ARI1A_MOUSE Isoform 1 of AT-rich interactive domain-containing protein 1A OS=Mus musculus OX=10090 GN=Arid1a PE=1 SV=1 CANONICAL=A2BH40-1" }, "locus": { "chromosome": "4", "start_pos": 133480922, "end_pos": 133407645, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000105897", "url": "https://www.ensembl.org/id/ENSMUST00000105897" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000101517", "url": "https://www.ensembl.org/id/ENSMUSP00000101517" } ] } }, { "isoform_ac": "A2BH40-2", "url": "https://www.uniprot.org/uniprot/A2BH40#A2BH40-2", "sequence": { "sequence": "MDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGSLSYAQQIPPYGQQGPSAYGQQGQTPYYNQQSPHPQQQPPYAQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQPPHQQSPTPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPASSSLSQQAAYPQPQPQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHSGVGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPNAGMAGSMNPMGAGGQMHGQPGIPPYGTLPPGRMAHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQESAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFPDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGSVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTPDSGMYSPSRYPPQQQQQQQQQQQQQRHDSYGNQFSTQGTPSSSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSAGQGQPQQQQLPAAQSQPASQPQAAQPSPQQDVYNQYSNAYPASATAATDRRPAGGPQNQFPFQFGRDRVSAPPGSSAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQNTGSATQGPAYHGVNRTDEMLHTDQRANHEGPWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMPNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPTPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFTKVYSPAHTEEEEEEHLDPKLEEEEEEGVGNDEEMAFLGKDKPSSENNEEKLVSKFDKLPVKIVQRNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKIELLPSRPYVPCPTPPRKHLTTVEGTPGTTEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGAKSAEATKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCDKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 1903, "header": "sp|A2BH40-2|ARI1A_MOUSE Isoform 2 of AT-rich interactive domain-containing protein 1A OS=Mus musculus OX=10090 GN=Arid1a PE=1 SV=1 CANONICAL=A2BH40-1" }, "locus": {} }, { "isoform_ac": "A2BH40-3", "url": "https://www.uniprot.org/uniprot/A2BH40#A2BH40-3", "sequence": { "sequence": "MAAQVAPAAASSLGNPPPPPSELKKAEQQQREEAGGEAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLPEPPGGGGGGGSSSSDGVGAPPHSAAAALPPPAYGFGQAYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPPQAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYGGGPQDGGAGKGPADMASQCWGAAAAAAAAAAAVSGGAQQRSHHAPMSPGSSGGGGQPLARTPQSSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGSLSYAQQIPPYGQQGPSAYGQQGQTPYYNQQSPHPQQQPPYAQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQPPHQQSPTPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPASSSLSQQAAYPQPQPQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHSGVGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPNAGMAGSMNPMGAGGQMHGQPGIPPYGTLPPGRMAHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQESAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFPDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGSVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTPDSGMYSPSRYPPQQQQQQQQQHDSYGNQFSTQGTPSSSPFPSQQTTMYQQQPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPTPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFTKVYSPAHTEEEEEEHLDPKLEEEEEEGVGNDEEMAFLGKDKPSSENNEEKLVSKFDKLPVKIVQRNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKIELLPSRPYVPCPTPPRKHLTTVEGTPGTTEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGAKSAEATKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCDKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2066, "header": "sp|A2BH40-3|ARI1A_MOUSE Isoform 3 of AT-rich interactive domain-containing protein 1A OS=Mus musculus OX=10090 GN=Arid1a PE=1 SV=1 CANONICAL=A2BH40-1" }, "locus": {} }, { "isoform_ac": "A2BH40-4", "url": "https://www.uniprot.org/uniprot/A2BH40#A2BH40-4", "sequence": { "sequence": "MDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGSLSYAQQIPPYGQQGPSAYGQQGQTPYYNQQSPHPQQQPPYAQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQPPHQQSPTPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPASSSLSQQAAYPQPQPQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHSGVGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPNAGMAGSMNPMGAGGQMHGQPGIPPYGTLPPGRMAHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQESAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMRSNSVGIQDAFPDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGSVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTPDSGMYSPSRYPPQQQQQQQQQQQQQRHDSYGNQFSTQGTPSSSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSAGQGQPQQQQLPAAQSQPASQPQAAQPSPQQDVYNQYSNAYPASATAATDRRPAGGPQNQFPFQFGRDRVSAPPGSSAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQNTGSATQGPAYHGVNRTDEMLHTDQRANHEGPWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMPNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPTPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFTKVYSPAHTEEEEEEHLDPKLEEEEEEGVGNDEEMAFLGKDKPSSENNEEKLVSKFDKLPVKIVQRNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKIELLPSRPYVPCPTPPRKHLTTVEGTPGTTEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGAKSAEATKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCDKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 1902, "header": "sp|A2BH40-4|ARI1A_MOUSE Isoform 4 of AT-rich interactive domain-containing protein 1A OS=Mus musculus OX=10090 GN=Arid1a PE=1 SV=1 CANONICAL=A2BH40-1" }, "locus": { "chromosome": "4", "start_pos": 133450350, "end_pos": 133407645, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000008024", "url": "https://www.ensembl.org/id/ENSMUST00000008024" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000008024", "url": "https://www.ensembl.org/id/ENSMUSP00000008024" } ] } }, { "isoform_ac": "E9Q495-1", "url": "https://www.uniprot.org/uniprot/A2BH40#E9Q495-1", "sequence": { "sequence": "MDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGSLSYAQQIPPYGQQGPSAYGQQGQTPYYNQQSPHPQQQPPYAQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQ", "length": 140, "header": "tr|E9Q495-1|E9Q495_MOUSE Computationally mapped isoform of AT-rich interactive domain-containing protein 1A OS=Mus musculus OX=10090 GN=Arid1a PE=1 SV=8 CANONICAL=A2BH40-1" }, "locus": { "chromosome": "4", "start_pos": 133450350, "end_pos": 133448092, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000139709", "url": "https://www.ensembl.org/id/ENSMUST00000139709" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000131950", "url": "https://www.ensembl.org/id/ENSMUSP00000131950" } ] } }, { "isoform_ac": "E9QAQ7-1", "url": "https://www.uniprot.org/uniprot/A2BH40#E9QAQ7-1", "sequence": { "sequence": 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}, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 765, "end_pos": 765, "kinase_uniprot_canonical_ac": "Q3UD01-1", "kinase_gene_name": "Atxn7l3b", "residue": "Ser", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" }, { "database": "iPTMnet", "id": "A2BH40", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2BH40" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 765, "end_pos": 765, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 773, "end_pos": 773, "kinase_uniprot_canonical_ac": "Q3UD01-1", "kinase_gene_name": "Atxn7l3b", "residue": "Ser", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" }, { "database": "iPTMnet", "id": "A2BH40", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2BH40" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 773, "end_pos": 773, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 77, "end_pos": 77, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ] } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Characterization of mammalian orthologues of the Drosophila osa gene: cDNA cloning, expression, chromosomal localization, and direct physical interaction with Brahma chromatin-remodeling complex.", "journal": "Genomics", "date": "2001", "authors": "Kozmik Z., Kralova J., Kreslova J., Machon O., Paces J., Vlcek C.", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "reference": [ { "type": "PubMed", "id": "11318604", "url": "https://glygen.org/publication/PubMed/11318604" } ] }, { "title": "The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.", "journal": "Cancer research", "date": "2005", "authors": "Nagl NG Jr, Patsialou A, Haines DS, Dallas PB, Beck GR Jr, Moran E", "evidence": [ { "database": "RefSeq", "id": "NP_001074288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288" } ], "reference": [ { "type": "PubMed", "id": "16230384", "url": "https://glygen.org/publication/PubMed/16230384" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" }, { "database": "UniProtKB", "id": "E9QAQ7", "url": "https://www.uniprot.org/uniprot/E9QAQ7" }, { "database": "iPTMnet", "id": "A2BH40", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2BH40" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "An essential switch in subunit composition of a chromatin remodeling complex during neural development.", "journal": "Neuron", "date": "2007", "authors": "Aebersold R., Crabtree G.R., Wu H., Wan M., Lessard J., Ranish J.A., Graef I.A., Staahl B.T., Winslow M.M., Wu J.I.", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "reference": [ { "type": "PubMed", "id": "17640523", "url": "https://glygen.org/publication/PubMed/17640523" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" }, { "database": "UniProtKB", "id": "E9QAQ7", "url": "https://www.uniprot.org/uniprot/E9QAQ7" }, { "database": "iPTMnet", "id": "A2BH40", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2BH40" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" }, { "database": "iPTMnet", "id": "A2BH40", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2BH40" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "SWI/SNF chromatin-remodeling factors: multiscale analyses and diverse functions.", "journal": "J. Biol. Chem.", "date": "2012", "authors": "Auerbach R.K., Euskirchen G., Snyder M.", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "reference": [ { "type": "PubMed", "id": "22952240", "url": "https://glygen.org/publication/PubMed/22952240" } ] }, { "title": "Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.", "journal": "Mol. Cell. Proteomics", "date": "2014", "authors": "Beausoleil S.A., Wang Y., Zhou J., Comb M.J., Guo A., Lee K.A., Aguiar M., Bedford M.T., Gu H., Jia X., Kornhauser J., Mulhern D., Ren J., Silva J.C., Vemulapalli V., Yang V.", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" }, { "database": "UniProtKB", "id": "E9QAQ7", "url": "https://www.uniprot.org/uniprot/E9QAQ7" }, { "database": "UniProtKB", "id": "E9Q495", "url": "https://www.uniprot.org/uniprot/E9Q495" } ], "reference": [ { "type": "PubMed", "id": "24129315", "url": "https://glygen.org/publication/PubMed/24129315" } ] }, { "title": "Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics.", "journal": "Sci. Adv.", "date": "2015", "authors": "Crabtree G.R., Kadoch C.", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "reference": [ { "type": "PubMed", "id": "26601204", "url": "https://glygen.org/publication/PubMed/26601204" } ] }, { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2144", "url": "https://glyconnect.expasy.org/browser/proteins/2144" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Chromatin remodeler ARID1A binds IRF3 to selectively induce antiviral interferon production in macrophages.", "journal": "Cell death & disease", "date": "2021", "authors": "Hu Y, Wang X, Song J, Wu J, Xu J, Chai Y, Ding Y, Wang B, Wang C, Zhao Y, Shen Z, Xu X, Cao X", "evidence": [ { "database": "RefSeq", "id": "NP_001074288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288" } ], "reference": [ { "type": "PubMed", "id": "34315861", "url": "https://glygen.org/publication/PubMed/34315861" } ] }, { "title": "Arid1a regulates neural stem/progenitor cell proliferation and differentiation during cortical development.", "journal": "Cell proliferation", "date": "2021", "authors": "Liu X, Dai SK, Liu PP, Liu CM", "evidence": [ { "database": "RefSeq", "id": "NP_001074288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288" } ], "reference": [ { "type": "PubMed", "id": "34562292", "url": "https://glygen.org/publication/PubMed/34562292" } ] }, { "title": "Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription.", "journal": "Cell reports", "date": "2021", "authors": "Blumli S, Wiechens N, Wu MY, Singh V, Gierlinski M, Schweikert G, Gilbert N, Naughton C, Sundaramoorthy R, Varghese J, Gourlay R, Soares R, Clark D, Owen-Hughes T", "evidence": [ { "database": "RefSeq", "id": "NP_001074288", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074288" } ], "reference": [ { "type": "PubMed", "id": "34731603", "url": "https://glygen.org/publication/PubMed/34731603" } ] } ], "pathway": [ { "id": "mmu:93760", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:93760", "resource": "KEGG Pathway" }, { "id": "R-MMU-3214858", "name": "RMTs methylate histone arginines", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3214858", "resource": "Reactome", "description": "RMTs methylate histone arginines" }, { "id": "R-MMU-8939243", "name": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A3E3-1", "protein_name": "AT-rich interaction domain 1A", "gene_name": "Arid1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYGGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQSSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGSLSYAQQIPPYGQQGPSAYGQQGQTPYYNQQSPHPQQQQQPPYSQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQPPHQQSQTPYPSQQSTTQQHPQSQPPYSQPQAQAPYQQQQPQQPASSTLSQQAAYPQPQPQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHSGMGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPSAGMAGSMNPLGAGGQMHGQPGIPPYGTLPPGRMTHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQESAVAMHVAANSIQNRPPGYPNMNQGGIMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMRSNSVGIQDAFPDGSEPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGGMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTPDSGMYSPSRYPPQQQQQQQQQQQQQQQQQQRHDSYGNQFSTQGTPSSSPFPSQQTTMYQQQQQQNYKRPMDGTYGPPAKRHEGELYSVPYSTGQGQPQQQQLPAAQSQSASQPQAAQPSPQQDVYNQYSNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQNTGSAPQGPAYHGVNRTDEMLHTDQRANHEGPWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPTPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRLTKVSSPAPTEEEEEEEHVDPKLEEEEEEGVENDEEMAFLGKDKPPSEKSEEKLVSKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKIELLPSRPCVPSPVPPRKHVTTVEGTPGTTEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGTKSTEANKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNAIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCDKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQSPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2021 }, "evidence": [ { "id": "A2BH40", "url": "https://omabrowser.org/oma/group/A2BH40/", "database": "OMA" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "O14497-1", "protein_name": "AT-rich interactive domain-containing protein 1A", "gene_name": "ARID1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEGGEEEEELLGPKLEEEEEEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2285 }, "evidence": [ { "id": "21216", "url": "http://www.informatics.jax.org/homology/21216", "database": "MGI" }, { "id": "A2BH40", "url": "https://omabrowser.org/oma/group/A2BH40/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 22, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "23129809" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "21873635" }, { "name": "forebrain development", "id": "GO:0030900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030900", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "23129809" }, { "name": "ATP-dependent chromatin remodeling", "id": "GO:0043044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043044", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "23129809" }, { "name": "glucocorticoid receptor signaling pathway", "id": "GO:0042921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042921", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "" }, { "name": "positive regulation of transcription, DNA-templated", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "23129809" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "11318604" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "18448678" }, { "name": "cardiac muscle cell differentiation", "id": "GO:0055007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055007", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "24335282" }, { "name": "androgen receptor signaling pathway", "id": "GO:0030521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030521", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "" }, { "name": "gastrulation", "id": "GO:0007369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007369", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "18448678" }, { "name": "toxin transport", "id": "GO:1901998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901998", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "23716698" }, { "name": "cardiac chamber development", "id": "GO:0003205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003205", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "23129809" }, { "name": "optic cup formation involved in camera-type eye development", "id": "GO:0003408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003408", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "23129809" }, { "name": "formation of primary germ layer", "id": "GO:0001704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001704", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "18448678" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "" }, { "name": "embryo implantation", "id": "GO:0007566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007566", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "18448678" }, { "name": "intracellular estrogen receptor signaling pathway", "id": "GO:0030520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030520", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "" }, { "name": "placenta blood vessel development", "id": "GO:0060674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060674", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "23129809" }, { "name": "heterochromatin maintenance", "id": "GO:0070829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070829", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "24335282" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "" }, { "name": "brahma complex", "id": "GO:0035060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035060", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "" }, { "name": "npBAF complex", "id": "GO:0071564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071564", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "17640523" }, { "name": "nBAF complex", "id": "GO:0071565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071565", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "17640523" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "23129809" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "A2BH40", "url": "https://www.uniprot.org/uniprot/A2BH40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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