{
    "uniprot_canonical_ac": "A2AVQ5-1",
    "uniprot_ac": "A2AVQ5",
    "uniprot_id": "LEXM_MOUSE",
    "mass": {
        "chemical_mass": 47584.0,
        "monoisotopic_mass": 47584.0
    },
    "refseq": {
        "ac": "NP_899005",
        "name": "lymphocyte expansion molecule",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_899005"
    },
    "gene_names": [
        {
            "name": "Lexm",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AVQ5",
            "id": "A2AVQ5"
        },
        {
            "name": "BC055111",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AVQ5",
            "id": "A2AVQ5"
        },
        {
            "name": "Lem",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AVQ5",
            "id": "A2AVQ5"
        },
        {
            "name": "Lexm",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_899005",
            "id": "NP_899005"
        }
    ],
    "protein_names": [
        {
            "name": "Lymphocyte expansion molecule",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AVQ5#names_and_taxonomy",
            "id": "A2AVQ5"
        },
        {
            "name": "lymphocyte expansion molecule",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_899005",
            "id": "NP_899005"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AVQ5",
                    "url": "https://www.uniprot.org/uniprot/A2AVQ5"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Lexm",
            "url": "https://www.uniprot.org/uniprot/A2AVQ5",
            "locus": {
                "chromosome": "4",
                "start_pos": 106617241,
                "end_pos": 106590909,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000054362",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000054362"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000054362",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000054362",
            "database": "Bgee"
        },
        {
            "id": "242602",
            "url": "https://www.ncbi.nlm.nih.gov/gene/242602",
            "database": "GeneID"
        },
        {
            "id": "IPR033557",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033557",
            "database": "InterPro"
        },
        {
            "id": "mmu:242602",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:242602",
            "database": "KEGG Pathway"
        },
        {
            "id": "2681853",
            "url": "http://www.informatics.jax.org/marker/MGI:2681853",
            "database": "MGI"
        },
        {
            "id": "PFTKGKC",
            "url": "https://omabrowser.org/oma/group/PFTKGKC/",
            "database": "OMA"
        },
        {
            "id": "826582at2759",
            "url": "http://www.orthodb.org/?query=826582at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PTHR34914",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34914",
            "database": "PANTHER"
        },
        {
            "id": "PR_A2AVQ5",
            "url": "http://purl.obolibrary.org/obo/PR_A2AVQ5",
            "database": "PRO"
        },
        {
            "id": "NP_899005",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_899005",
            "database": "RefSeq"
        },
        {
            "id": "A2AVQ5",
            "url": "https://www.uniprot.org/uniprot/A2AVQ5",
            "database": "UniProtKB"
        },
        {
            "id": "A2AVQ5-1",
            "url": "https://www.uniprot.org/uniprot/A2AVQ5-1",
            "database": "UniProtKB"
        },
        {
            "id": "F6X5R4",
            "url": "https://www.uniprot.org/uniprot/F6X5R4",
            "database": "UniProtKB"
        },
        {
            "id": "F6X5R4-1",
            "url": "https://www.uniprot.org/uniprot/F6X5R4-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MRPRTHGAPPRNIMSTIPKWFKGAPFGVQSHRFDVSAVYPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKDTCFSKKFLEQKLGSGWSQAHEATRLTQLPHFHYQAIKKEKEQQVHKRGPGSYNIKDFITELQKKPQSKRGLLSSGETRFRGFIGNYYPGPGNYGEKGNPYTQLEEKAWNRSHSDGLMCRVSNKPPLFHQGSGLGPGTYTIKSDLETFVKKSTGNRGPYDIFSGERSSPLPYGHYSVQKMKPKELTDYKSFLDEMNSQHKKKQGVFSKYPRDPKHPTERIFWTTLSQCPKNMDIAGPGSWLPHETEQKHVNRPPFLLASKRCGLKAYQMILGTWNPVGVGRYLNTTLMESIDRRQRYRSLYMSEPKRYLQDLTRDRLMQKRITPITKGKCRPTVDYNSDPTP",
        "length": 414,
        "header": "sp|A2AVQ5-1|LEXM_MOUSE Isoform 1 of Lymphocyte expansion molecule  OS=Mus musculus OX=10090 GN=Lexm PE=2 SV=1 CANONICAL=A2AVQ5-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A2AVQ5-1",
            "url": "https://www.uniprot.org/uniprot/A2AVQ5#A2AVQ5-1",
            "sequence": {
                "sequence": "MRPRTHGAPPRNIMSTIPKWFKGAPFGVQSHRFDVSAVYPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKDTCFSKKFLEQKLGSGWSQAHEATRLTQLPHFHYQAIKKEKEQQVHKRGPGSYNIKDFITELQKKPQSKRGLLSSGETRFRGFIGNYYPGPGNYGEKGNPYTQLEEKAWNRSHSDGLMCRVSNKPPLFHQGSGLGPGTYTIKSDLETFVKKSTGNRGPYDIFSGERSSPLPYGHYSVQKMKPKELTDYKSFLDEMNSQHKKKQGVFSKYPRDPKHPTERIFWTTLSQCPKNMDIAGPGSWLPHETEQKHVNRPPFLLASKRCGLKAYQMILGTWNPVGVGRYLNTTLMESIDRRQRYRSLYMSEPKRYLQDLTRDRLMQKRITPITKGKCRPTVDYNSDPTP",
                "length": 414,
                "header": "sp|A2AVQ5-1|LEXM_MOUSE Isoform 1 of Lymphocyte expansion molecule  OS=Mus musculus OX=10090 GN=Lexm PE=2 SV=1 CANONICAL=A2AVQ5-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 106474416,
                "end_pos": 106448815,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000067387",
                        "url": "https://www.ensembl.org/id/ENSMUST00000067387"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000066732",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000066732"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F6X5R4-1",
            "url": "https://www.uniprot.org/uniprot/A2AVQ5#F6X5R4-1",
            "sequence": {
                "sequence": "NTTLMESIDRRQRYRSLYMSEPKRYLQDLTRDRLMQKRITPITKGKCRPTVDYNSDPTP",
                "length": 59,
                "header": "tr|F6X5R4-1|F6X5R4_MOUSE Computationally mapped isoform of Lymphocyte expansion molecule  OS=Mus musculus OX=10090 GN=Lexm PE=4 SV=1 CANONICAL=A2AVQ5-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 106464592,
                "end_pos": 106448815,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000126324",
                        "url": "https://www.ensembl.org/id/ENSMUST00000126324"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000118338",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000118338"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "T cell metabolism. The protein LEM promotes CD8+ T cell immunity through effects on mitochondrial respiration.",
            "journal": "Science",
            "date": "2015",
            "authors": "Wang L., Ichimura T., Haas R., Richter K., Oxenius A., Abdi R., Ashton-Rickardt P.G., Choi O., Crouse J., Heathcote D., Lovo E., Mauro C., Okoye I., Pallmer K., Rutschmann S.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AVQ5",
                    "url": "https://www.uniprot.org/uniprot/A2AVQ5"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "25883318",
                    "url": "https://glygen.org/publication/PubMed/25883318"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:242602",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:242602",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "B1H283-1",
            "protein_name": "Lymphocyte expansion molecule",
            "gene_name": "Lexm",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MSTIRKWFKGAPFGVQSHRFDVSAVHPNQKKFSTFTEAPYSRHHSVELSHIGPGTYNSKETCFSKKFLEQKLGAGWARAQEASRLTQLPHFHFQAIKKEREQQANKRGPGSYNIKDFLTELQKKPQSKRGLLSSGETRFRGLIGNYYPGPGNYGEKGNPYTQLEKNSWNRSHSDGLMCRLSSKPPPLSHQGSGLGPGTYTIKSDIETFVEKSTGTRGPYDIFSGERSSPVPYGHYSVQKKKPRELTSFKSFVDELNAPHKKKQGGFSKYPRDPKHPTERIYWTTLSQCPKDVNVAGPGSWLPHETEQKHVNRPPFLLASKRSGLKACQMLLGTWNPVGVGRYLNTTLMEKIDRRQRYRSLFMSEPKRYLHDLNRDKLLQERITPFTKGKCRPTVDYNSDPTP",
                "length": 402
            },
            "evidence": [
                {
                    "id": "17630",
                    "url": "http://www.informatics.jax.org/homology/17630",
                    "database": "MGI"
                },
                {
                    "id": "A2AVQ5",
                    "url": "https://omabrowser.org/oma/group/A2AVQ5/",
                    "database": "OMA"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q3ZCV2-1",
            "protein_name": "Lymphocyte expansion molecule",
            "gene_name": "LEXM",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MRESQDAAGAHGWNRVGSTATKWFTGAPFGVQSHRFDISAVYPNWKKFSTFTEAPYSTRYSTQVSHIGPGTYSSKETCFSKKKLMKEVDTGWAKAQEATRLTQLPHFQYQAIMKEKRLKEQKLGPGSYNLKDFLEQLREKPCSTRGLLSSGEVRFRGLTGNYYPGPGNYGEKGNPYTKLEENAWNRSHSEGLMCRMSNKPHPRPHQGSGLGPGTYFFKSDLETYVARSVGTRGPYDTFSGDRSKPLPYGHYSMQKKKPRELMNFKSFVEELNSHHNKKHGVFSKLPRNPKTPTERIYWANLSQCPRTLATSGPSFWLPQEKKCKPVNQPPFLLTSKGSGAKACQMIMGSWNPVGVGRYLNTWLMETKDRRQRYRSLFLSGSKRYLSDLARDMLMQERITPFTKGKCPPTVDYNSDPTP",
                "length": 418
            },
            "evidence": [
                {
                    "id": "17630",
                    "url": "http://www.informatics.jax.org/homology/17630",
                    "database": "MGI"
                },
                {
                    "id": "A2AVQ5",
                    "url": "https://omabrowser.org/oma/group/A2AVQ5/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {},
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 182,
            "end_pos": 184,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 356,
            "end_pos": 358,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ]
}