{
    "uniprot_canonical_ac": "A2AVC0-1",
    "uniprot_ac": "A2AVC0",
    "uniprot_id": "A2AVC0_MOUSE",
    "mass": {
        "chemical_mass": 36117.0,
        "monoisotopic_mass": 36117.0
    },
    "refseq": {
        "ac": "NP_666851",
        "name": "olfactory receptor 1153",
        "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666851"
    },
    "gene_names": [
        {
            "name": "Olfr1153",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AVC0",
            "id": "A2AVC0"
        },
        {
            "name": "MOR177-7",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666851",
            "id": "NP_666851"
        },
        {
            "name": "Olfr1153",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666851",
            "id": "NP_666851"
        }
    ],
    "protein_names": [
        {
            "name": "Olfactory receptor",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AVC0#names_and_taxonomy",
            "id": "A2AVC0"
        },
        {
            "name": "olfactory receptor 1153",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666851",
            "id": "NP_666851"
        },
        {
            "name": "olfactory receptor MOR177-7; GA_x6K02T2Q125-49395950-49396882",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666851",
            "id": "NP_666851"
        }
    ],
    "function": [
        {
            "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_666851",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666851"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AVC0",
                    "url": "https://www.uniprot.org/uniprot/A2AVC0"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Olfr1153",
            "url": "https://www.uniprot.org/uniprot/A2AVC0",
            "locus": {
                "chromosome": "2",
                "start_pos": 87894962,
                "end_pos": 87898310,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000048197",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000048197"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000048197",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000048197",
            "database": "Bgee"
        },
        {
            "id": "258633",
            "url": "https://www.ncbi.nlm.nih.gov/gene/258633",
            "database": "GeneID"
        },
        {
            "id": "IPR000276",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276",
            "database": "InterPro"
        },
        {
            "id": "IPR000725",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725",
            "database": "InterPro"
        },
        {
            "id": "IPR017452",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452",
            "database": "InterPro"
        },
        {
            "id": "mmu:258633",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:258633",
            "database": "KEGG Pathway"
        },
        {
            "id": "3030987",
            "url": "http://www.informatics.jax.org/marker/MGI:3030987",
            "database": "MGI"
        },
        {
            "id": "CALQWLI",
            "url": "https://omabrowser.org/oma/group/CALQWLI/",
            "database": "OMA"
        },
        {
            "id": "966398at2759",
            "url": "http://www.orthodb.org/?query=966398at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PF13853",
            "url": "http://pfam.xfam.org/family/PF13853",
            "database": "Pfam"
        },
        {
            "id": "NP_666851",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666851",
            "database": "RefSeq"
        },
        {
            "id": "A0A1L1SUW4",
            "url": "https://www.uniprot.org/uniprot/A0A1L1SUW4",
            "database": "UniProtKB"
        },
        {
            "id": "A0A1L1SUW4-1",
            "url": "https://www.uniprot.org/uniprot/A0A1L1SUW4-1",
            "database": "UniProtKB"
        },
        {
            "id": "A2AVC0",
            "url": "https://www.uniprot.org/uniprot/A2AVC0",
            "database": "UniProtKB"
        },
        {
            "id": "A2AVC0-1",
            "url": "https://www.uniprot.org/uniprot/A2AVC0-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MQFIKQRRMEVGNCSATEFLLLGITNNPVIKVILFTTFLIVYLIILIENLGMIILIRMNSQLHTPMYFFLSHLSFSDICYSTAVGPKMLVGLIFKNNSIPFIDCAVQFFIFCIFTDAECVLLAVMAFDRYKAISNPLMYAVDMSRVVCYQLLAVVYLVGMVDALTHTTLTFHLCFCQSKEINHFFCDVPPLLLLSCSDTEVNELVIFTLFGFIELSTISGVLVSYCYIISSVLKIRSAEGRFKAFSTCTSHLTVVAIFQGTMLFMYFRPSSAYSLDQDKMTSLFYTLVIPMLNPLIYSLRNKDVKASVKRSLKSRISF",
        "length": 318,
        "header": "tr|A2AVC0-1|A2AVC0_MOUSE Isoform 1 of Olfactory receptor  OS=Mus musculus OX=10090 GN=Olfr1153 PE=3 SV=1 CANONICAL=A2AVC0-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A1L1SUW4-1",
            "url": "https://www.uniprot.org/uniprot/A2AVC0#A0A1L1SUW4-1",
            "sequence": {
                "sequence": "MEVGNCSATEFLLLGITNNPVIKVILFTTFLIVYLIILIENLGMIILIRMNSQLHTPMYFFLSHLSFSDICYSTAVGPKMLVGLIFKNNSIPFIDCAVQFFIFCIFTDAECVLLAVMAFDRYKAISNPLMYAVDMSRVVCYQLLAVVYLVGMVDALTHTTLTFHLCFCQSKEINHFFCDVPPLLLLSCSDTEVNELVIFTLFGFIELSTISGVLVSYCYIISSVLKIRSAEGRFKAFSTCTSHLTVVAIFQGTMLFMYFRPSSAYSLDQDKMTSLFYTLVIPMLNPLIYSLRNKDVKASVKRSLKSRISF",
                "length": 310,
                "header": "tr|A0A1L1SUW4-1|A0A1L1SUW4_MOUSE Computationally mapped isoform of Olfactory receptor  OS=Mus musculus OX=10090 GN=Olfr1153 PE=3 SV=1 CANONICAL=A2AVC0-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 87727474,
                "end_pos": 87726545,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000217436",
                        "url": "https://www.ensembl.org/id/ENSMUST00000217436"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000150945",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000150945"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2AVC0-1",
            "url": "https://www.uniprot.org/uniprot/A2AVC0#A2AVC0-1",
            "sequence": {
                "sequence": "MQFIKQRRMEVGNCSATEFLLLGITNNPVIKVILFTTFLIVYLIILIENLGMIILIRMNSQLHTPMYFFLSHLSFSDICYSTAVGPKMLVGLIFKNNSIPFIDCAVQFFIFCIFTDAECVLLAVMAFDRYKAISNPLMYAVDMSRVVCYQLLAVVYLVGMVDALTHTTLTFHLCFCQSKEINHFFCDVPPLLLLSCSDTEVNELVIFTLFGFIELSTISGVLVSYCYIISSVLKIRSAEGRFKAFSTCTSHLTVVAIFQGTMLFMYFRPSSAYSLDQDKMTSLFYTLVIPMLNPLIYSLRNKDVKASVKRSLKSRISF",
                "length": 318,
                "header": "tr|A2AVC0-1|A2AVC0_MOUSE Isoform 1 of Olfactory receptor  OS=Mus musculus OX=10090 GN=Olfr1153 PE=3 SV=1 CANONICAL=A2AVC0-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 87727474,
                "end_pos": 87726521,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000052300",
                        "url": "https://www.ensembl.org/id/ENSMUST00000052300"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000057839",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000057839"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:258633",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:258633",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZB20-1",
            "protein_name": "Olfactory receptor",
            "gene_name": "LOC100911380",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MEVGNCSATEFLLLGITNNPVIKVILFSTFLIVYLMILIENLGMIILIKMNPQLHTPMYFFLSHLSFSDICYSTAVGPKMLVGLMTKSNAIPFIGCAVQFFIFCIFTDAECVLLAVMAFDRYKAISNPLLYAVDMSGVVCYQLLAVVYLVGMVDALTHTTLTFCLCFCRSNEINHFFCDVPPLLLLSCSDTEVNELVIFTLFGFIELSTISGVLISYCYIISSVLKIRSTEGRFKAFSTCTSHLTAVAIFQGTMLFMYFRPSSAYSLDQDKMTSLFYTLVIPLLNPLIYSLRNKDVKASVKKSLRNRISI",
                "length": 310
            },
            "evidence": [
                {
                    "id": "27230",
                    "url": "http://www.informatics.jax.org/homology/27230",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "G protein-coupled receptor activity",
                        "id": "GO:0004930",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AVC0",
                                "url": "https://www.uniprot.org/uniprot/A2AVC0"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "olfactory receptor activity",
                        "id": "GO:0004984",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AVC0",
                                "url": "https://www.uniprot.org/uniprot/A2AVC0"
                            }
                        ],
                        "pmid": "14611657"
                    },
                    {
                        "name": "odorant binding",
                        "id": "GO:0005549",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AVC0",
                                "url": "https://www.uniprot.org/uniprot/A2AVC0"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AVC0",
                                "url": "https://www.uniprot.org/uniprot/A2AVC0"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "integral component of membrane",
                        "id": "GO:0016021",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AVC0",
                                "url": "https://www.uniprot.org/uniprot/A2AVC0"
                            }
                        ],
                        "pmid": "14611657"
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "G protein-coupled receptor signaling pathway",
                        "id": "GO:0007186",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AVC0",
                                "url": "https://www.uniprot.org/uniprot/A2AVC0"
                            }
                        ],
                        "pmid": "14611657"
                    },
                    {
                        "name": "sensory perception of smell",
                        "id": "GO:0007608",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AVC0",
                                "url": "https://www.uniprot.org/uniprot/A2AVC0"
                            }
                        ],
                        "pmid": "14611657"
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 13,
            "end_pos": 15,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 96,
            "end_pos": 98,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}