{
    "uniprot_canonical_ac": "A2ASZ8-1",
    "uniprot_ac": "A2ASZ8",
    "uniprot_id": "SCMC2_MOUSE",
    "mass": {
        "chemical_mass": 52621.0,
        "monoisotopic_mass": 52621.0
    },
    "refseq": {
        "ac": "NP_001157829",
        "name": "calcium-binding mitochondrial carrier protein SCaMC-2 isoform 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157829"
    },
    "gene_names": [
        {
            "name": "Slc25a25",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8",
            "id": "A2ASZ8"
        },
        {
            "name": "1110030N17Rik; MCSC; mKIAA1896",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157829",
            "id": "NP_001157829"
        },
        {
            "name": "Kiaa1896",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8",
            "id": "A2ASZ8"
        },
        {
            "name": "Scamc2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8",
            "id": "A2ASZ8"
        },
        {
            "name": "Slc25a25",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157829",
            "id": "NP_001157829"
        }
    ],
    "protein_names": [
        {
            "name": "Calcium-binding mitochondrial carrier protein SCaMC-2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8#names_and_taxonomy",
            "id": "A2ASZ8"
        },
        {
            "name": "Small calcium-binding mitochondrial carrier protein 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8#names_and_taxonomy",
            "id": "A2ASZ8"
        },
        {
            "name": "Solute carrier family 25 member 25",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8#names_and_taxonomy",
            "id": "A2ASZ8"
        },
        {
            "name": "calcium-binding mitochondrial carrier protein SCaMC-2 isoform 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157829",
            "id": "NP_001157829"
        },
        {
            "name": "mitochondrial Ca2+-dependent solute carrier; calcium-binding mitochondrial carrier protein SCaMC-2; solute carrier family 25 member 25; small calcium-binding mitochondrial carrier protein 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157829",
            "id": "NP_001157829"
        }
    ],
    "function": [
        {
            "annotation": "Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2ASZ8",
                    "url": "https://www.uniprot.org/uniprot/A2ASZ8#function"
                }
            ]
        },
        {
            "annotation": "Induction of Slc25a25 in mice with an intact gene may contribute to an alternative thermogenic pathway for the maintenance of body temperature during cold stress.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001157829",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157829"
                },
                {
                    "database": "PubMed",
                    "id": "21296886",
                    "url": "https://glygen.org/publication/PubMed/21296886"
                }
            ]
        },
        {
            "annotation": "These findings suggest that KD feeding induces expression of the muscle circadian gene Slc25a25 via neural pathways, and that SLC25A25 might be involved in muscle thermogenesis under KD-induced hypothermia in mammals. Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001157829",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157829"
                },
                {
                    "database": "PubMed",
                    "id": "28588221",
                    "url": "https://glygen.org/publication/PubMed/28588221"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2ASZ8",
                    "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Slc25a25",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8",
            "locus": {
                "chromosome": "2",
                "start_pos": 32451445,
                "end_pos": 32414487,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000026819",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000026819"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000026819",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000026819",
            "database": "Bgee"
        },
        {
            "id": "227731",
            "url": "https://www.ncbi.nlm.nih.gov/gene/227731",
            "database": "GeneID"
        },
        {
            "id": "IPR002048",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048",
            "database": "InterPro"
        },
        {
            "id": "IPR002067",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067",
            "database": "InterPro"
        },
        {
            "id": "IPR002167",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002167",
            "database": "InterPro"
        },
        {
            "id": "IPR011992",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992",
            "database": "InterPro"
        },
        {
            "id": "IPR018108",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108",
            "database": "InterPro"
        },
        {
            "id": "IPR023395",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395",
            "database": "InterPro"
        },
        {
            "id": "mmu:227731",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:227731",
            "database": "KEGG Pathway"
        },
        {
            "id": "1915913",
            "url": "http://www.informatics.jax.org/marker/MGI:1915913",
            "database": "MGI"
        },
        {
            "id": "FDEWRNF",
            "url": "https://omabrowser.org/oma/group/FDEWRNF/",
            "database": "OMA"
        },
        {
            "id": "442523at2759",
            "url": "http://www.orthodb.org/?query=442523at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PF00153",
            "url": "http://pfam.xfam.org/family/PF00153",
            "database": "Pfam"
        },
        {
            "id": "PF13499",
            "url": "http://pfam.xfam.org/family/PF13499",
            "database": "Pfam"
        },
        {
            "id": "PF13833",
            "url": "http://pfam.xfam.org/family/PF13833",
            "database": "Pfam"
        },
        {
            "id": "PR_A2ASZ8",
            "url": "http://purl.obolibrary.org/obo/PR_A2ASZ8",
            "database": "PRO"
        },
        {
            "id": "NP_001157829",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157829",
            "database": "RefSeq"
        },
        {
            "id": "A0A0A6YWC1",
            "url": "https://www.uniprot.org/uniprot/A0A0A6YWC1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A0A6YWC1-1",
            "url": "https://www.uniprot.org/uniprot/A0A0A6YWC1-1",
            "database": "UniProtKB"
        },
        {
            "id": "A2ASZ8",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8",
            "database": "UniProtKB"
        },
        {
            "id": "A2ASZ8-1",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8-1",
            "database": "UniProtKB"
        },
        {
            "id": "A2ASZ8-2",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8-2",
            "database": "UniProtKB"
        },
        {
            "id": "A2ASZ8-3",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8-3",
            "database": "UniProtKB"
        },
        {
            "id": "A2ASZ8-4",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8-4",
            "database": "UniProtKB"
        },
        {
            "id": "A2ASZ8-5",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8-5",
            "database": "UniProtKB"
        },
        {
            "id": "F6RC04",
            "url": "https://www.uniprot.org/uniprot/F6RC04",
            "database": "UniProtKB"
        },
        {
            "id": "F6RC04-1",
            "url": "https://www.uniprot.org/uniprot/F6RC04-1",
            "database": "UniProtKB"
        },
        {
            "id": "Z4YLR9",
            "url": "https://www.uniprot.org/uniprot/Z4YLR9",
            "database": "UniProtKB"
        },
        {
            "id": "Z4YLR9-1",
            "url": "https://www.uniprot.org/uniprot/Z4YLR9-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MLCLCLYVPIAGAAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIVGGFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAKEGVAAFYKGYIPNMLGIIPYAGIDLAVYETLKNTWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKQILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR",
        "length": 469,
        "header": "sp|A2ASZ8-1|SCMC2_MOUSE Isoform 1 of Calcium-binding mitochondrial carrier protein SCaMC-2  OS=Mus musculus OX=10090 GN=Slc25a25 PE=1 SV=1 CANONICAL=A2ASZ8-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0A6YWC1-1",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8#A0A0A6YWC1-1",
            "sequence": {
                "sequence": "MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQ",
                "length": 112,
                "header": "tr|A0A0A6YWC1-1|SCMC2_MOUSE Computationally mapped isoform of Calcium-binding mitochondrial carrier protein SCaMC-2  OS=Mus musculus OX=10090 GN=Slc25a25 PE=1 SV=1 CANONICAL=A2ASZ8-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 32311379,
                "end_pos": 32309060,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000153886",
                        "url": "https://www.ensembl.org/id/ENSMUST00000153886"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000141486",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000141486"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2ASZ8-1",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8#A2ASZ8-1",
            "sequence": {
                "sequence": "MLCLCLYVPIAGAAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIVGGFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAKEGVAAFYKGYIPNMLGIIPYAGIDLAVYETLKNTWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKQILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR",
                "length": 469,
                "header": "sp|A2ASZ8-1|SCMC2_MOUSE Isoform 1 of Calcium-binding mitochondrial carrier protein SCaMC-2  OS=Mus musculus OX=10090 GN=Slc25a25 PE=1 SV=1 CANONICAL=A2ASZ8-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 32313964,
                "end_pos": 32306153,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000113307",
                        "url": "https://www.ensembl.org/id/ENSMUST00000113307"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000108932",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000108932"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2ASZ8-2",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8#A2ASZ8-2",
            "sequence": {
                "sequence": "MVSSVLCRCVASPPPDAAATASSSASSPASVGDPCGGAVCGGPDHQLRLWSLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELRKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIVGGFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAKEGVAAFYKGYIPNMLGIIPYAGIDLAVYETLKNTWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKQILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR",
                "length": 502,
                "header": "sp|A2ASZ8-2|SCMC2_MOUSE Isoform 2 of Calcium-binding mitochondrial carrier protein SCaMC-2  OS=Mus musculus OX=10090 GN=Slc25a25 PE=1 SV=1 CANONICAL=A2ASZ8-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 32341336,
                "end_pos": 32306153,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000113310",
                        "url": "https://www.ensembl.org/id/ENSMUST00000113310"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000108936",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000108936"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2ASZ8-3",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8#A2ASZ8-3",
            "sequence": {
                "sequence": "MVSSVLCRCVASPPPDAAATASSSASSPASVGDPCGGAVCGGPDHQLRLWSLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELRKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIVGGFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAKEGVAAFYKGYIPNMLGIIPYAGIDLAVYETLKNTWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKQILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR",
                "length": 514,
                "header": "sp|A2ASZ8-3|SCMC2_MOUSE Isoform 3 of Calcium-binding mitochondrial carrier protein SCaMC-2  OS=Mus musculus OX=10090 GN=Slc25a25 PE=1 SV=1 CANONICAL=A2ASZ8-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 32341336,
                "end_pos": 32306153,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000028160",
                        "url": "https://www.ensembl.org/id/ENSMUST00000028160"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000028160",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000028160"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2ASZ8-4",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8#A2ASZ8-4",
            "sequence": {
                "sequence": "MLQTLWHFLSSFLPRAECQDSREGIDHGVRGTQAPARGDQMSTFLGKQNGRAEATEKRPTILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIVGGFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAKEGVAAFYKGYIPNMLGIIPYAGIDLAVYETLKNTWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKQILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR",
                "length": 489,
                "header": "sp|A2ASZ8-4|SCMC2_MOUSE Isoform 4 of Calcium-binding mitochondrial carrier protein SCaMC-2  OS=Mus musculus OX=10090 GN=Slc25a25 PE=1 SV=1 CANONICAL=A2ASZ8-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 32320759,
                "end_pos": 32306153,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000113308",
                        "url": "https://www.ensembl.org/id/ENSMUST00000113308"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000108933",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000108933"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2ASZ8-5",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8#A2ASZ8-5",
            "sequence": {
                "sequence": "MLQTLWHFLSSFLPRAECQDSREGIDHGVRGTQAPARGDQMSTFLGKQNGRAEATEKRPTILLVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIVGGFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAKEGVAAFYKGYIPNMLGIIPYAGIDLAVYETLKNTWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKQILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR",
                "length": 501,
                "header": "sp|A2ASZ8-5|SCMC2_MOUSE Isoform 5 of Calcium-binding mitochondrial carrier protein SCaMC-2  OS=Mus musculus OX=10090 GN=Slc25a25 PE=1 SV=1 CANONICAL=A2ASZ8-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 32320759,
                "end_pos": 32306153,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000052119",
                        "url": "https://www.ensembl.org/id/ENSMUST00000052119"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000060581",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000060581"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F6RC04-1",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8#F6RC04-1",
            "sequence": {
                "sequence": "XTGSPKLFPSPGKVYLDIIFALQKEQKRSQVFDLPPAEKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKRIRTGHFWGPVTYMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWW",
                "length": 184,
                "header": "tr|F6RC04-1|SCMC2_MOUSE Computationally mapped isoform of Calcium-binding mitochondrial carrier protein SCaMC-2  OS=Mus musculus OX=10090 GN=Slc25a25 PE=1 SV=1 CANONICAL=A2ASZ8-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 32321116,
                "end_pos": 32309143,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000127961",
                        "url": "https://www.ensembl.org/id/ENSMUST00000127961"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000121932",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000121932"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Z4YLR9-1",
            "url": "https://www.uniprot.org/uniprot/A2ASZ8#Z4YLR9-1",
            "sequence": {
                "sequence": "MTGSPKLFPSPGKVYLDIIFALQKEQKRSQVFDLPPAEKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIVGGFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQETL",
                "length": 263,
                "header": "tr|Z4YLR9-1|SCMC2_MOUSE Computationally mapped isoform of Calcium-binding mitochondrial carrier protein SCaMC-2  OS=Mus musculus OX=10090 GN=Slc25a25 PE=1 SV=1 CANONICAL=A2ASZ8-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 32321117,
                "end_pos": 32307430,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000136361",
                        "url": "https://www.ensembl.org/id/ENSMUST00000136361"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000115617",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000115617"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Inactivation of the mitochondrial carrier SLC25A25 (ATP-Mg2+/Pi transporter) reduces physical endurance and metabolic efficiency in mice.",
            "journal": "The Journal of biological chemistry",
            "date": "2011",
            "authors": "Anunciado-Koza RP, Zhang J, Ukropec J, Bajpeyi S, Koza RA, Rogers RC, Cefalu WT, Mynatt RL, Kozak LP",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001157829",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157829"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "21296886",
                    "url": "https://glygen.org/publication/PubMed/21296886"
                }
            ]
        },
        {
            "title": "Ketogenic diet induces expression of the muscle circadian gene Slc25a25 via neural pathway that might be involved in muscle thermogenesis.",
            "journal": "Scientific reports",
            "date": "2017",
            "authors": "Nakao R, Shimba S, Oishi K",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001157829",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157829"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "28588221",
                    "url": "https://glygen.org/publication/PubMed/28588221"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:227731",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:227731",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q6KCM7-1",
            "protein_name": "Calcium-binding mitochondrial carrier protein SCaMC-2",
            "gene_name": "SLC25A25",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR",
                "length": 469
            },
            "evidence": [
                {
                    "id": "62165",
                    "url": "http://www.informatics.jax.org/homology/62165",
                    "database": "MGI"
                },
                {
                    "id": "A2ASZ8",
                    "url": "https://omabrowser.org/oma/group/A2ASZ8/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8K3P6-1",
            "protein_name": "Calcium-binding mitochondrial carrier protein SCaMC-2",
            "gene_name": "Slc25a25",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MLCLCLYVPIAGEAQTEFQYFESKGLPTELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMCIIGGFTQMIREGGAKSLWRGNGINVLKIAPESAIKFMAYEQMKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCAKRILAKEGVAAFYKGYIPNMLGIIPYAGIDLAVYETLKNTWLQRYAVNSADPGVFVLLACGTISSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKQILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR",
                "length": 469
            },
            "evidence": [
                {
                    "id": "62165",
                    "url": "http://www.informatics.jax.org/homology/62165",
                    "database": "MGI"
                },
                {
                    "id": "A2ASZ8",
                    "url": "https://omabrowser.org/oma/group/A2ASZ8/",
                    "database": "OMA"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "calcium ion binding",
                        "id": "GO:0005509",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ATP transmembrane transporter activity",
                        "id": "GO:0005347",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005347",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "mitochondrial inner membrane",
                        "id": "GO:0005743",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "integral component of membrane",
                        "id": "GO:0016021",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrion",
                        "id": "GO:0005739",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": "23344948"
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 10,
                "go_terms": [
                    {
                        "name": "transmembrane transport",
                        "id": "GO:0055085",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "adipose tissue development",
                        "id": "GO:0060612",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060612",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": "21296886"
                    },
                    {
                        "name": "response to food",
                        "id": "GO:0032094",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032094",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": "21296886"
                    },
                    {
                        "name": "multicellular organism growth",
                        "id": "GO:0035264",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035264",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": "21296886"
                    },
                    {
                        "name": "response to activity",
                        "id": "GO:0014823",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014823",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": "21296886"
                    },
                    {
                        "name": "calcium ion transmembrane transport",
                        "id": "GO:0070588",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": "21296886"
                    },
                    {
                        "name": "response to dietary excess",
                        "id": "GO:0002021",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002021",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": "21296886"
                    },
                    {
                        "name": "ATP metabolic process",
                        "id": "GO:0046034",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046034",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": "21296886"
                    },
                    {
                        "name": "camera-type eye development",
                        "id": "GO:0043010",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": "21296886"
                    },
                    {
                        "name": "cellular respiration",
                        "id": "GO:0045333",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045333",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ASZ8",
                                "url": "https://www.uniprot.org/uniprot/A2ASZ8"
                            }
                        ],
                        "pmid": "21296886"
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 129,
            "end_pos": 131,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 169,
            "end_pos": 171,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ]
}