{ "uniprot_canonical_ac": "A2ASV2-1", "uniprot_ac": "A2ASV2", "uniprot_id": "A2ASV2_MOUSE", "mass": { "chemical_mass": 35031.0, "monoisotopic_mass": 35031.0 }, "refseq": { "ac": "NP_001011758", "name": "olfactory receptor 1016", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011758" }, "gene_names": [ { "name": "Olfr1016", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2ASV2", "id": "A2ASV2" }, { "name": "MOR213-9", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011758", "id": "NP_001011758" }, { "name": "Olfr1016", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011758", "id": "NP_001011758" } ], "protein_names": [ { "name": "Olfactory receptor", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2ASV2#names_and_taxonomy", "id": "A2ASV2" }, { "name": "olfactory receptor 1016", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011758", "id": "NP_001011758" }, { "name": "olfactory receptor MOR213-9; olfactory receptor MOR188-1; GA_x6K02T2Q125-47278889-47277960", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011758", "id": "NP_001011758" } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001011758", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011758" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2ASV2", "url": "https://www.uniprot.org/uniprot/A2ASV2" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Olfr1016", "url": "https://www.uniprot.org/uniprot/A2ASV2", "locus": { "chromosome": "2", "start_pos": 85802544, "end_pos": 85797618, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000075209", "url": "https://www.ensembl.org/id/ENSMUSG00000075209" } ] } } ], "crossref": [ { "id": "ENSMUSG00000075209", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000075209", "database": "Bgee" }, { "id": "257915", "url": "https://www.ncbi.nlm.nih.gov/gene/257915", "database": "GeneID" }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro" }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro" }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro" }, { "id": "mmu:257915", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:257915", "database": "KEGG Pathway" }, { "id": "3030850", "url": "http://www.informatics.jax.org/marker/MGI:3030850", "database": "MGI" }, { "id": "STKLCAF", "url": "https://omabrowser.org/oma/group/STKLCAF/", "database": "OMA" }, { "id": "927196at2759", "url": "http://www.orthodb.org/?query=927196at2759", "database": "OrthoDB" }, { "id": "PF13853", "url": "http://pfam.xfam.org/family/PF13853", "database": "Pfam" }, { "id": "R-MMU-381753", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-381753", "database": "Reactome" }, { "id": "NP_001011758", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011758", "database": "RefSeq" }, { "id": "A2ASV2", "url": "https://www.uniprot.org/uniprot/A2ASV2", "database": "UniProtKB" }, { "id": "A2ASV2-1", "url": "https://www.uniprot.org/uniprot/A2ASV2-1", "database": "UniProtKB" } ], "sequence": { "sequence": "MERGNHTVSEFILLGFTSDPTTQLVLFVMFLIMYTLSVLGNITLIVLICNDSRLHTPMYFFIGNLSFLDLWLSNVYTPKILAICISENKSISFASCVAQFFFSAGLDYSECYLLAAMAYDRYVAISKPLIYSQAISMKLCAFFVAASYMGGFINSSIITKKTFTFDFCNDNVIDDFFCDLLPLVNLACGGKEGYQTLMYFLLTSNVMIPIALILASYIFIIATILRIRSTQGRMKAFSTCSSHLISVTLYYGSILYIYSRPRTRYSLDSDKVVSTFYTVVFPMLNPFIYSLRNKDVKEAMNKLFKIIPL", "length": 309, "header": "tr|A2ASV2-1|A2ASV2_MOUSE Isoform 1 of Olfactory receptor OS=Mus musculus OX=10090 GN=Olfr1016 PE=3 SV=1 CANONICAL=A2ASV2-1" }, "isoforms": [ { "isoform_ac": "A2ASV2-1", "url": "https://www.uniprot.org/uniprot/A2ASV2#A2ASV2-1", "sequence": { "sequence": "MERGNHTVSEFILLGFTSDPTTQLVLFVMFLIMYTLSVLGNITLIVLICNDSRLHTPMYFFIGNLSFLDLWLSNVYTPKILAICISENKSISFASCVAQFFFSAGLDYSECYLLAAMAYDRYVAISKPLIYSQAISMKLCAFFVAASYMGGFINSSIITKKTFTFDFCNDNVIDDFFCDLLPLVNLACGGKEGYQTLMYFLLTSNVMIPIALILASYIFIIATILRIRSTQGRMKAFSTCSSHLISVTLYYGSILYIYSRPRTRYSLDSDKVVSTFYTVVFPMLNPFIYSLRNKDVKEAMNKLFKIIPL", "length": 309, "header": "tr|A2ASV2-1|A2ASV2_MOUSE Isoform 1 of Olfactory receptor OS=Mus musculus OX=10090 GN=Olfr1016 PE=3 SV=1 CANONICAL=A2ASV2-1" }, "locus": { "chromosome": "2", "start_pos": 85630612, "end_pos": 85629686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000217410", "url": "https://www.ensembl.org/id/ENSMUST00000217410" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000149631", "url": "https://www.ensembl.org/id/ENSMUSP00000149631" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "mmu:257915", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:257915", "resource": "KEGG Pathway" }, { "id": "R-MMU-381753", "name": "Olfactory Signaling Pathway", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-381753", "resource": "Reactome", "description": "Olfactory Signaling Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZVQ4-1", "protein_name": "Olfactory receptor", "gene_name": "Olr459", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERGNHTVSEFILLGFTSDPTTQLVLFVMFLIMYTLTVLGNCILMVLICSDPKLHTPMYFFIGNLSFLDLWLSTVYTPKILVICISENKSMSFASCVAQFFFSAGLDYSECYLLAAMAYDRYVAISKPLIYSQAISIKQCAFFVAASYMGGFINSSIITKKTFTFDFCNDNIIDDFFCDLLPLVNLACGGKEGYQALMYFLLTSNVMIPIALILASYIIIIATILRIRSTQGRLKAFSTCSSHLISVTLYYGSILYIYSRPRTSYSLDTDKVVSTFYTVVFPMLNPFIYSLRNKDVKEALNKLLKIIPL", "length": 309 }, "evidence": [ { "id": "83133", "url": "http://www.informatics.jax.org/homology/83133", "database": "MGI" } ], "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A2ASV2", "url": "https://www.uniprot.org/uniprot/A2ASV2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A2ASV2", "url": "https://www.uniprot.org/uniprot/A2ASV2" } ], "pmid": "14611657" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A2ASV2", "url": "https://www.uniprot.org/uniprot/A2ASV2" } ], "pmid": "" }, { "name": "integral component of membrane", "id": "GO:0016021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", "evidence": [ { "database": "UniProtKB", "id": "A2ASV2", "url": "https://www.uniprot.org/uniprot/A2ASV2" } ], "pmid": "14611657" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A2ASV2", "url": "https://www.uniprot.org/uniprot/A2ASV2" } ], "pmid": "14611657" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A2ASV2", "url": "https://www.uniprot.org/uniprot/A2ASV2" } ], "pmid": "14611657" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" } ] }