{
    "uniprot_canonical_ac": "A2ARM1-1",
    "uniprot_ac": "A2ARM1",
    "uniprot_id": "PATL2_MOUSE",
    "mass": {
        "chemical_mass": 59639.0,
        "monoisotopic_mass": 59639.0
    },
    "refseq": {
        "ac": "NP_080527",
        "name": "protein PAT1 homolog 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080527"
    },
    "gene_names": [
        {
            "name": "Patl2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2ARM1",
            "id": "A2ARM1"
        },
        {
            "name": "4930424G05Rik; Pat1a",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080527",
            "id": "NP_080527"
        },
        {
            "name": "Patl2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080527",
            "id": "NP_080527"
        }
    ],
    "protein_names": [
        {
            "name": "Protein PAT1 homolog 2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2ARM1#names_and_taxonomy",
            "id": "A2ARM1"
        },
        {
            "name": "PAT1-like protein 2; protein PAT1 homolog a",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080527",
            "id": "NP_080527"
        },
        {
            "name": "PAT1-like protein 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2ARM1#names_and_taxonomy",
            "id": "A2ARM1"
        },
        {
            "name": "Pat1a",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2ARM1#names_and_taxonomy",
            "id": "A2ARM1"
        },
        {
            "name": "Protein PAT1 homolog a",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2ARM1#names_and_taxonomy",
            "id": "A2ARM1"
        },
        {
            "name": "protein PAT1 homolog 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080527",
            "id": "NP_080527"
        }
    ],
    "function": [
        {
            "annotation": "HPat1b localizes to P-bodies, while mPat1a-GFP is either found weakly in P-bodies or disperses P-bodies in a dominant-negative fashion.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_080527",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080527"
                },
                {
                    "database": "PubMed",
                    "id": "20826699",
                    "url": "https://glygen.org/publication/PubMed/20826699"
                }
            ]
        },
        {
            "annotation": "RNA-binding protein that acts as a translational repressor.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2ARM1",
                    "url": "https://www.uniprot.org/uniprot/A2ARM1#function"
                },
                {
                    "database": "PubMed",
                    "id": "Q4V7K4",
                    "url": "https://glygen.org/publication/PubMed/Q4V7K4"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:1100",
            "recommended_name": {
                "id": "DOID:1100",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:1100",
                "name": "ovarian disease",
                "description": "A female reproductive system disease that is located_in the ovary."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "1100",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:1100"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2ARM1",
                    "url": "https://www.uniprot.org/uniprot/A2ARM1"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Patl2",
            "url": "https://www.uniprot.org/uniprot/A2ARM1",
            "locus": {
                "chromosome": "2",
                "start_pos": 122186189,
                "end_pos": 122120108,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000027233",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000027233"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000027233",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000027233",
            "database": "Bgee"
        },
        {
            "id": "67578",
            "url": "https://www.ncbi.nlm.nih.gov/gene/67578",
            "database": "GeneID"
        },
        {
            "id": "IPR019167",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019167",
            "database": "InterPro"
        },
        {
            "id": "IPR039900",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039900",
            "database": "InterPro"
        },
        {
            "id": "mmu:67578",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:67578",
            "database": "KEGG Pathway"
        },
        {
            "id": "1914828",
            "url": "http://www.informatics.jax.org/marker/MGI:1914828",
            "database": "MGI"
        },
        {
            "id": "CYSEQQS",
            "url": "https://omabrowser.org/oma/group/CYSEQQS/",
            "database": "OMA"
        },
        {
            "id": "950451at2759",
            "url": "http://www.orthodb.org/?query=950451at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PTHR21551",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21551",
            "database": "PANTHER"
        },
        {
            "id": "PF09770",
            "url": "http://pfam.xfam.org/family/PF09770",
            "database": "Pfam"
        },
        {
            "id": "PR_A2ARM1",
            "url": "http://purl.obolibrary.org/obo/PR_A2ARM1",
            "database": "PRO"
        },
        {
            "id": "NP_080527",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080527",
            "database": "RefSeq"
        },
        {
            "id": "A2ARM1",
            "url": "https://www.uniprot.org/uniprot/A2ARM1",
            "database": "UniProtKB"
        },
        {
            "id": "A2ARM1-1",
            "url": "https://www.uniprot.org/uniprot/A2ARM1-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MKCLEGLHLQQRPSKFSVSLAPEEGLVCAFQLEEEKENEDECVCSDQAPEVKEEGCGLGDPAIVSAFQNTQVPQQRGLHSSHRVKVSGALGMSSASLHFMWQSVFPRASSPAHHFGPQQPSPDPFLFYSPLTPWPPKLSLPSHLTQLHPQHQQILQQQQRWRRRRSPTARSVPAQKPWSREPAASDAYANLMTRKEKDWVIRVQMVQLQSENPRLDDYYYQKYYQKLEKRQADKELLGQKTRAESLKLVTPYIQKPEVYESVVRIEGSLGQVAVSTCFSPRRAIDAVSHGTQEQDTGAASSQRLRVLSQIEKMFLQLLKIEEGQNDGLPQLYHTREQSSQVEKLFQALKTQEQNNLEEAADNLLQVLSVRKGKVLVARLLPFLPPDQAVSLLLYITYHLPLLIQRDMADQGLHMLFKPLGKYISHLTFHQLLHAMQGLMLLSPGSSERPVSVVLQNQFGISLLYALLSHGEQLVSLDPSLRSSSDCATWTDLVILIAWEIAQLPAASLAEPLAFPRNLLPCSAITWTSN",
        "length": 529,
        "header": "sp|A2ARM1-1|PATL2_MOUSE Isoform 1 of Protein PAT1 homolog 2  OS=Mus musculus OX=10090 GN=Patl2 PE=2 SV=1 CANONICAL=A2ARM1-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A2ARM1-1",
            "url": "https://www.uniprot.org/uniprot/A2ARM1#A2ARM1-1",
            "sequence": {
                "sequence": "MKCLEGLHLQQRPSKFSVSLAPEEGLVCAFQLEEEKENEDECVCSDQAPEVKEEGCGLGDPAIVSAFQNTQVPQQRGLHSSHRVKVSGALGMSSASLHFMWQSVFPRASSPAHHFGPQQPSPDPFLFYSPLTPWPPKLSLPSHLTQLHPQHQQILQQQQRWRRRRSPTARSVPAQKPWSREPAASDAYANLMTRKEKDWVIRVQMVQLQSENPRLDDYYYQKYYQKLEKRQADKELLGQKTRAESLKLVTPYIQKPEVYESVVRIEGSLGQVAVSTCFSPRRAIDAVSHGTQEQDTGAASSQRLRVLSQIEKMFLQLLKIEEGQNDGLPQLYHTREQSSQVEKLFQALKTQEQNNLEEAADNLLQVLSVRKGKVLVARLLPFLPPDQAVSLLLYITYHLPLLIQRDMADQGLHMLFKPLGKYISHLTFHQLLHAMQGLMLLSPGSSERPVSVVLQNQFGISLLYALLSHGEQLVSLDPSLRSSSDCATWTDLVILIAWEIAQLPAASLAEPLAFPRNLLPCSAITWTSN",
                "length": 529,
                "header": "sp|A2ARM1-1|PATL2_MOUSE Isoform 1 of Protein PAT1 homolog 2  OS=Mus musculus OX=10090 GN=Patl2 PE=2 SV=1 CANONICAL=A2ARM1-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 121959997,
                "end_pos": 121951669,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000028665",
                        "url": "https://www.ensembl.org/id/ENSMUST00000028665"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000028665",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000028665"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Distinct functions of maternal and somatic Pat1 protein paralogs.",
            "journal": "RNA",
            "date": "2010",
            "authors": "Kress M., Marnef A., Standart N., Weil D., Balasubramanian S., Bugaut A., Maldonado M.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2ARM1",
                    "url": "https://www.uniprot.org/uniprot/A2ARM1"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_080527",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080527"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "20826699",
                    "url": "https://glygen.org/publication/PubMed/20826699"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:67578",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:67578",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "C9JE40-1",
            "protein_name": "Protein PAT1 homolog 2",
            "gene_name": "PATL2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MNCLEGPGKTCGPLASEEELVSACQLEKEEENEGEEEEEEEDEEDLDPDLDPDLEEEENDLGDPAVLGAVHNTQRALLSSPGVKAPGMLGMSLASLHFLWQTLDYLSPIPFWPTFPSTSSPAQHFGPRLPSPDPTLFCSLLTSWPPRFSHLTQLHPRHQRILQQQQHSQTPSPPAKKPWSQQPDPYANLMTRKEKDWVIKVQMVQLQSAKPRLDDYYYQEYYQKLEKKQADEELLGRRNRVESLKLVTPYIPKAEAYESVVRIEGSLGQVAVSTCFSPRRAIDAVPHGTQEQDIEAASSQRLRVLYRIEKMFLQLLEIEEGWKYRPPPPCFSEQQSNQVEKLFQTLKTQEQNNLEEAADGFLQVLSVRKGKALVARLLPFLPQDQAVTILLAITHHLPLLVRRDVADQALQMLFKPLGKCISHLTLHELLQGLQGLTLLPPGSSERPVTVVLQNQFGISLLYALLSHGEQLVSLHSSLEEPNSDHTAWTDMVVLIAWEIAQMPTASLAEPLAFPSNLLPLFCHHVDKQLVQQLEARMEFAWIY",
                "length": 543
            },
            "evidence": [
                {
                    "id": "12155",
                    "url": "http://www.informatics.jax.org/homology/12155",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "D3Z954-1",
            "protein_name": "PAT1 homolog 2",
            "gene_name": "Patl2",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MKCLEGLHLQHRPSKFSVPLAPEEGLECAFQLEEEEKENEEKFVCSDWAPEGKEEGNDLWDPAIVSAIQNTQVPQQRGLHSSPTVRASGALGMSPASLHFLCQSVFPRTSSPAHHFGPQQPSPDPFLFCSPLTPWPPKLRLPSHLTQLHPQHQKILQQQQGWPKRMFLLARRVPGQKPRSRESDAYANLMTRKEKDWVIRVQMVQLQSENPRLDDYYYQKYYQKLEKRQADQELLGQRNRAQSLKLVTPYIQKSEVYESVVRIEGSLGQVAVSTCFSPRRAIDAVSHGTQEQDTGAASSQRLRVLSQIEKMFLQLLKIEEGQNDGLPQHYHLREQSNQVEKLFQALKTQEQNNLEEAADNLLQVLSVRKGKIFVARLLPFLLQDQAVSLLLYITYHLPLLIQRDMADQSLQMLFKPLRKYIRHLTFPQLLHALQGLMLLSPDSSERPVSVVLQNQFGISLLYALLSHGEQLVSLDSSLQSSSDCVAWTDLVILVAWEIAQLPAASLAEPLAFPRNLPCSTTTWTNN",
                "length": 526
            },
            "evidence": [
                {
                    "id": "A2ARM1",
                    "url": "https://omabrowser.org/oma/group/A2ARM1/",
                    "database": "OMA"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 4,
                "go_terms": [
                    {
                        "name": "deadenylation-dependent decapping of nuclear-transcribed mRNA",
                        "id": "GO:0000290",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000290",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "negative regulation of translation",
                        "id": "GO:0017148",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "P-body assembly",
                        "id": "GO:0033962",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033962",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "negative regulation of cytoplasmic mRNA processing body assembly",
                        "id": "GO:0010607",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010607",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": "20826699"
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 5,
                "go_terms": [
                    {
                        "name": "RNA binding",
                        "id": "GO:0003723",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "translation repressor activity",
                        "id": "GO:0030371",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030371",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": "20826699"
                    },
                    {
                        "name": "G-quadruplex RNA binding",
                        "id": "GO:0002151",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002151",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": "20826699"
                    },
                    {
                        "name": "poly(U) RNA binding",
                        "id": "GO:0008266",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008266",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": "20826699"
                    },
                    {
                        "name": "poly(G) binding",
                        "id": "GO:0034046",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034046",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": "20826699"
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": "20826699"
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": "20826699"
                    },
                    {
                        "name": "P-body",
                        "id": "GO:0000932",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ARM1",
                                "url": "https://www.uniprot.org/uniprot/A2ARM1"
                            }
                        ],
                        "pmid": "20826699"
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ]
}