{
    "uniprot_canonical_ac": "A2AML7-1",
    "uniprot_ac": "A2AML7",
    "uniprot_id": "A2AML7_MOUSE",
    "mass": {
        "chemical_mass": 61932.0,
        "monoisotopic_mass": 61932.0
    },
    "refseq": {
        "ac": "NP_694742",
        "name": "Kruppel-like factor 18",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_694742"
    },
    "gene_names": [
        {
            "name": "Zfp352",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AML7",
            "id": "A2AML7"
        },
        {
            "name": "2czf48",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_694742",
            "id": "NP_694742"
        },
        {
            "name": "Zfp352",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_694742",
            "id": "NP_694742"
        }
    ],
    "protein_names": [
        {
            "name": "Kruppel-like factor 18",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_694742",
            "id": "NP_694742"
        },
        {
            "name": "Zinc finger protein 352",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AML7#names_and_taxonomy",
            "id": "A2AML7"
        }
    ],
    "function": [
        {
            "annotation": "The major Zfp352 promoter, designated P1 and located upstream of exon 1, is utilized in both early embryos and in somatic cells",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_694742",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_694742"
                },
                {
                    "database": "PubMed",
                    "id": "12420299",
                    "url": "https://glygen.org/publication/PubMed/12420299"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AML7",
                    "url": "https://www.uniprot.org/uniprot/A2AML7"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Zfp352",
            "url": "https://www.uniprot.org/uniprot/A2AML7",
            "locus": {
                "chromosome": "4",
                "start_pos": 90218820,
                "end_pos": 90225702,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000070902",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000070902"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000070902",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000070902",
            "database": "Bgee"
        },
        {
            "id": "236537",
            "url": "https://www.ncbi.nlm.nih.gov/gene/236537",
            "database": "GeneID"
        },
        {
            "id": "IPR013087",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087",
            "database": "InterPro"
        },
        {
            "id": "IPR036236",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236",
            "database": "InterPro"
        },
        {
            "id": "mmu:236537",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:236537",
            "database": "KEGG Pathway"
        },
        {
            "id": "2387418",
            "url": "http://www.informatics.jax.org/marker/MGI:2387418",
            "database": "MGI"
        },
        {
            "id": "CESQRIT",
            "url": "https://omabrowser.org/oma/group/CESQRIT/",
            "database": "OMA"
        },
        {
            "id": "1318335at2759",
            "url": "http://www.orthodb.org/?query=1318335at2759",
            "database": "OrthoDB"
        },
        {
            "id": "NP_694742",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_694742",
            "database": "RefSeq"
        },
        {
            "id": "A2AML7",
            "url": "https://www.uniprot.org/uniprot/A2AML7",
            "database": "UniProtKB"
        },
        {
            "id": "A2AML7-1",
            "url": "https://www.uniprot.org/uniprot/A2AML7-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MEMAENTGASQPGPCNTQPSPVESSQLFSGQSSEMLTWKQTVMESASCSTQETTCTQNSTAYPGKAIGFHFGQPFENTSWNQQVVSAEQKISPAGLYHTQLNSAPQICLPPQKTTRVDTRETFYNEDYWMRTLNSDKTLLTQNTAMCENQRVTFDNHQIALYGSHAGQDPNVGHAFASEHDWTSYNSHMTTRNGGHLTLYESQMTAPSCSQTLHPNQIITSFSEQNYFEDQQSNLAVNNGFYGNQVILPNGYQAFYEPQMRANFDQTNDQMKSFSGQNVCKGQENLLSGECSLSGYQTSGYRCDQDLIVNPQVTSPIGGQPLSDFQTQTSSFDTALPGSKRTRPSAEDNLACPLETSPTSEETLYLGQMRTSVDQNFYSSQNGTPNIKESLDPQVTSFSLQAPYVGESSYPSCSPLIQKQPQKNSSASSLVQRQHPEMKLDFKTQSPVSQKDPSPLKLYFCTYKGCTKFYKRAYHLKEHQKKHTDKRKYGCDEPGCTWSFFRLCDLNRHKEKHNGERFYACPLCSTNYSRLLYLKKHLEKKHAQAQPTTAT",
        "length": 551,
        "header": "tr|A2AML7-1|A2AML7_MOUSE Isoform 1 of Zinc finger protein 352  OS=Mus musculus OX=10090 GN=Zfp352 PE=4 SV=1 CANONICAL=A2AML7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A2AML7-1",
            "url": "https://www.uniprot.org/uniprot/A2AML7#A2AML7-1",
            "sequence": {
                "sequence": "MEMAENTGASQPGPCNTQPSPVESSQLFSGQSSEMLTWKQTVMESASCSTQETTCTQNSTAYPGKAIGFHFGQPFENTSWNQQVVSAEQKISPAGLYHTQLNSAPQICLPPQKTTRVDTRETFYNEDYWMRTLNSDKTLLTQNTAMCENQRVTFDNHQIALYGSHAGQDPNVGHAFASEHDWTSYNSHMTTRNGGHLTLYESQMTAPSCSQTLHPNQIITSFSEQNYFEDQQSNLAVNNGFYGNQVILPNGYQAFYEPQMRANFDQTNDQMKSFSGQNVCKGQENLLSGECSLSGYQTSGYRCDQDLIVNPQVTSPIGGQPLSDFQTQTSSFDTALPGSKRTRPSAEDNLACPLETSPTSEETLYLGQMRTSVDQNFYSSQNGTPNIKESLDPQVTSFSLQAPYVGESSYPSCSPLIQKQPQKNSSASSLVQRQHPEMKLDFKTQSPVSQKDPSPLKLYFCTYKGCTKFYKRAYHLKEHQKKHTDKRKYGCDEPGCTWSFFRLCDLNRHKEKHNGERFYACPLCSTNYSRLLYLKKHLEKKHAQAQPTTAT",
                "length": 551,
                "header": "tr|A2AML7-1|A2AML7_MOUSE Isoform 1 of Zinc finger protein 352  OS=Mus musculus OX=10090 GN=Zfp352 PE=4 SV=1 CANONICAL=A2AML7-1"
            },
            "locus": {
                "chromosome": "4",
                "start_pos": 90113514,
                "end_pos": 90111862,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000080541",
                        "url": "https://www.ensembl.org/id/ENSMUST00000080541"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000079383",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000079383"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Display of different modes of transcription by the promoters of an early embryonic gene, Zfp352, in preimplantation embryos and in somatic cells.",
            "journal": "Molecular reproduction and development",
            "date": "2003",
            "authors": "Liu TY, Chen HH, Lee KH, Choo KB",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_694742",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_694742"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12420299",
                    "url": "https://glygen.org/publication/PubMed/12420299"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:236537",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:236537",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZJE1-1",
            "protein_name": "Zinc finger protein 352",
            "gene_name": "Zfp352",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MDMAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKQTVMASSYFNPYETACTQNSTAHRGKATDSYFGEPSETASFIQQVVSAEQNKSPEGSLFMKLNSTATSCLPQPLDTRKTLYNEGYWRRTLNSDKTLLIQNTDLCESQRITFGNHPVALSGSHAGQVPNVDHLDSVWDQTFGGDLEMPFSDDSYYSQMTTKYGGHLTLYESQMIAPSCNQVLDTDQFVTSFYEQNPFGDQQRSPVTENKFYGDQMIVPNAYQAFYEPQVRDNSDQINFDSRMASFSGQNICSGQESIFQDEHSLSGFQTSGYRCDQDWIMNHQVISPIGGQTLYDSQKPTSTFNTTPHGSKRTTSSAEDNLAWHPETSSSSEETLYMGQMRASVDQNVYASQNGTANTEESLEPEVTSLSNQAPDVGESSDSSSSPLIRIQSQGISSASGLDQGQHPQIRLDLKTQSPVSPEKPPTLKRYSCTYQGCEKSYTKSHHLKDHMRKHTGEKPFVCDQIGCNWKFFRSIDLNRHKKKHSGERPYACPKCNKNYSRPYYLKQHQVSHIQALPTTAN",
                "length": 559
            },
            "evidence": [
                {
                    "id": "A2AML7",
                    "url": "https://omabrowser.org/oma/group/A2AML7/",
                    "database": "OMA"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "regulation of transcription by RNA polymerase II",
                        "id": "GO:0006357",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AML7",
                                "url": "https://www.uniprot.org/uniprot/A2AML7"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding",
                        "id": "GO:0000978",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AML7",
                                "url": "https://www.uniprot.org/uniprot/A2AML7"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "DNA-binding transcription factor activity, RNA polymerase II-specific",
                        "id": "GO:0000981",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AML7",
                                "url": "https://www.uniprot.org/uniprot/A2AML7"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 382,
            "end_pos": 384,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 424,
            "end_pos": 426,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 527,
            "end_pos": 529,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 58,
            "end_pos": 60,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 77,
            "end_pos": 79,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ]
}