{ "uniprot_canonical_ac": "A2AHJ4-1", "uniprot_ac": "A2AHJ4", "uniprot_id": "BRWD3_MOUSE", "mass": { "chemical_mass": 202942.0, "monoisotopic_mass": 202942.0 }, "refseq": { "ac": "NP_001074946", "name": "bromodomain and WD repeat-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074946" }, "gene_names": [ { "name": "Brwd3", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2AHJ4", "id": "A2AHJ4" }, { "name": "Brodl; D030064D06Rik; Gm10452; Gm596", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074946", "id": "NP_001074946" }, { "name": "Brwd3", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074946", "id": "NP_001074946" }, { "name": "Gm596", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2AHJ4", "id": "A2AHJ4" } ], "protein_names": [ { "name": "Bromodomain and WD repeat-containing protein 3", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2AHJ4#names_and_taxonomy", "id": "A2AHJ4" }, { "name": "bromo domain-containing protein disrupted in leukemia", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074946", "id": "NP_001074946" }, { "name": "bromodomain and WD repeat-containing protein 3", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074946", "id": "NP_001074946" } ], "function": [ { "annotation": "Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Brwd3", "url": "https://www.uniprot.org/uniprot/A2AHJ4", "locus": { "chromosome": "X", "start_pos": 108834372, "end_pos": 108737016, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000063663", "url": "https://www.ensembl.org/id/ENSMUSG00000063663" } ] } } ], "crossref": [ { "id": "ENSMUSG00000063663", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000063663", "database": "Bgee" }, { "id": "382236", "url": "https://www.ncbi.nlm.nih.gov/gene/382236", "database": "GeneID" }, { "id": "A2AHJ4", "url": "https://www.ebi.ac.uk/intact/interactors/id:A2AHJ4*", "database": "IntAct" }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro" }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro" }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro" }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro" }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro" }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro" }, { "id": "mmu:382236", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:382236", "database": "KEGG Pathway" }, { "id": "3029414", "url": "http://www.informatics.jax.org/marker/MGI:3029414", "database": "MGI" }, { "id": "TVVTSWK", "url": "https://omabrowser.org/oma/group/TVVTSWK/", "database": "OMA" }, { "id": "240778at2759", "url": "http://www.orthodb.org/?query=240778at2759", "database": "OrthoDB" }, { "id": "PF00400", "url": "http://pfam.xfam.org/family/PF00400", "database": "Pfam" }, { "id": "PF00439", "url": "http://pfam.xfam.org/family/PF00439", "database": "Pfam" }, { "id": "PR_A2AHJ4", "url": "http://purl.obolibrary.org/obo/PR_A2AHJ4", "database": "PRO" }, { "id": "NP_001074946", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074946", "database": "RefSeq" }, { "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4", "database": "UniProtKB" }, { "id": "A2AHJ4-1", "url": "https://www.uniprot.org/uniprot/A2AHJ4-1", "database": "UniProtKB" }, { "id": "A2AHJ4-2", "url": "https://www.uniprot.org/uniprot/A2AHJ4-2", "database": "UniProtKB" }, { "id": "A2AHJ4-3", "url": "https://www.uniprot.org/uniprot/A2AHJ4-3", "database": "UniProtKB" }, { "id": "G3UXF9", "url": "https://www.uniprot.org/uniprot/G3UXF9", "database": "UniProtKB" }, { "id": "G3UXF9-1", "url": "https://www.uniprot.org/uniprot/G3UXF9-1", "database": "UniProtKB" }, { "id": "G3UZT0", "url": "https://www.uniprot.org/uniprot/G3UZT0", "database": "UniProtKB" }, { "id": "G3UZT0-1", "url": "https://www.uniprot.org/uniprot/G3UZT0-1", "database": "UniProtKB" } ], "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGNNLTSAEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQEESILDGIIRELQREQDLRLINEGDVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRRSGQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKKPSYPIQRNDYQPSCGRSLRRTQRKRQHTYLTRSNIEHNSQASSQTSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSESSSSDSSSEYSDWIADAGINLQPPKRQTRQATQKIYSSSEDENLKLEDRQKKPKQTKKKKGGLVSMAGEPNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPDGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCSDILDTYNKIKAEDPDSSDLEEDSEMVDLDSDGPGTSSGRRAKCRGRRQSLKCNPDAWKKQCEELLSLIYEREDSEPFRQPADPQSYPVQQQQEGESSQSVPPDRQDPSLSEDYQDGIDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENHIKNIISDYKSAIQSQKRRRPRYRKRLRSSSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVAYARTSSPFSSPVSDAAEGVSLYLLDDEGDGPFSPSSFSGYSRSGNSHDPGKAKSFRNRVLPAKQDHSLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKEQVHLSSSESGELGSSLSSESTSGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHTNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGGRGRGGGGGRGRGRGRGGRGASRGSSRAKRARVADDEFDTMFSGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1799, "header": "sp|A2AHJ4-1|BRWD3_MOUSE Isoform 1 of Bromodomain and WD repeat-containing protein 3 OS=Mus musculus OX=10090 GN=Brwd3 PE=1 SV=1 CANONICAL=A2AHJ4-1" }, "isoforms": [ { "isoform_ac": "A2AHJ4-1", "url": "https://www.uniprot.org/uniprot/A2AHJ4#A2AHJ4-1", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGNNLTSAEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQEESILDGIIRELQREQDLRLINEGDVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRRSGQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKKPSYPIQRNDYQPSCGRSLRRTQRKRQHTYLTRSNIEHNSQASSQTSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSESSSSDSSSEYSDWIADAGINLQPPKRQTRQATQKIYSSSEDENLKLEDRQKKPKQTKKKKGGLVSMAGEPNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPDGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCSDILDTYNKIKAEDPDSSDLEEDSEMVDLDSDGPGTSSGRRAKCRGRRQSLKCNPDAWKKQCEELLSLIYEREDSEPFRQPADPQSYPVQQQQEGESSQSVPPDRQDPSLSEDYQDGIDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENHIKNIISDYKSAIQSQKRRRPRYRKRLRSSSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVAYARTSSPFSSPVSDAAEGVSLYLLDDEGDGPFSPSSFSGYSRSGNSHDPGKAKSFRNRVLPAKQDHSLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKEQVHLSSSESGELGSSLSSESTSGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHTNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGGRGRGGGGGRGRGRGRGGRGASRGSSRAKRARVADDEFDTMFSGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1799, "header": "sp|A2AHJ4-1|BRWD3_MOUSE Isoform 1 of Bromodomain and WD repeat-containing protein 3 OS=Mus musculus OX=10090 GN=Brwd3 PE=1 SV=1 CANONICAL=A2AHJ4-1" }, "locus": { "chromosome": "X", "start_pos": 107877735, "end_pos": 107786625, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000150434", "url": "https://www.ensembl.org/id/ENSMUST00000150434" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000123588", "url": "https://www.ensembl.org/id/ENSMUSP00000123588" } ] } }, { "isoform_ac": "A2AHJ4-2", "url": "https://www.uniprot.org/uniprot/A2AHJ4#A2AHJ4-2", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQVRIMISSLPG", "length": 281, "header": "sp|A2AHJ4-2|BRWD3_MOUSE Isoform 2 of Bromodomain and WD repeat-containing protein 3 OS=Mus musculus OX=10090 GN=Brwd3 PE=1 SV=1 CANONICAL=A2AHJ4-1" }, "locus": {} }, { "isoform_ac": "A2AHJ4-3", "url": "https://www.uniprot.org/uniprot/A2AHJ4#A2AHJ4-3", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVGFFFVALTVLELYVDQAGLCLSSAGIKVVCHMTSYITF", "length": 181, "header": "sp|A2AHJ4-3|BRWD3_MOUSE Isoform 3 of Bromodomain and WD repeat-containing protein 3 OS=Mus musculus OX=10090 GN=Brwd3 PE=1 SV=1 CANONICAL=A2AHJ4-1" }, "locus": { "chromosome": "X", "start_pos": 107877735, "end_pos": 107864809, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000101283", "url": "https://www.ensembl.org/id/ENSMUST00000101283" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000098841", "url": "https://www.ensembl.org/id/ENSMUSP00000098841" } ] } }, { "isoform_ac": "G3UXF9-1", "url": "https://www.uniprot.org/uniprot/A2AHJ4#G3UXF9-1", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDL", "length": 60, "header": "tr|G3UXF9-1|G3UXF9_MOUSE Computationally mapped isoform of Bromodomain and WD repeat-containing protein 3 OS=Mus musculus OX=10090 GN=Brwd3 PE=1 SV=1 CANONICAL=A2AHJ4-1" }, "locus": { "chromosome": "X", "start_pos": 107877735, "end_pos": 107876820, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000144521", "url": "https://www.ensembl.org/id/ENSMUST00000144521" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000133674", "url": "https://www.ensembl.org/id/ENSMUSP00000133674" } ] } }, { "isoform_ac": "G3UZT0-1", "url": "https://www.uniprot.org/uniprot/A2AHJ4#G3UZT0-1", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLTVRVHYGMGLLLQPSTEADPQNYL", "length": 84, "header": "tr|G3UZT0-1|G3UZT0_MOUSE Computationally mapped isoform of Bromodomain and WD repeat-containing protein 3 OS=Mus musculus OX=10090 GN=Brwd3 PE=1 SV=1 CANONICAL=A2AHJ4-1" }, "locus": { "chromosome": "X", "start_pos": 107877735, "end_pos": 107868439, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000041866", "url": "https://www.ensembl.org/id/ENSMUST00000041866" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000134621", "url": "https://www.ensembl.org/id/ENSMUSP00000134621" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 1574, "end_pos": 1574, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" } ] }, { "start_pos": 1576, "end_pos": 1576, "kinase_uniprot_canonical_ac": "Q3UD01-1", "kinase_gene_name": "Atxn7l3b", "residue": "Ser", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" }, { "database": "iPTMnet", "id": "A2AHJ4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AHJ4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 1576, "end_pos": 1576, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 1760, "end_pos": 1760, "kinase_uniprot_canonical_ac": "Q3UD01-1", "kinase_gene_name": "Atxn7l3b", "residue": "Ser", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" }, { "database": "iPTMnet", "id": "A2AHJ4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AHJ4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 1760, "end_pos": 1760, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 693, "end_pos": 693, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" } ] }, { "start_pos": 884, "end_pos": 884, "kinase_uniprot_canonical_ac": "Q3UD01-1", "kinase_gene_name": "Atxn7l3b", "residue": "Ser", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" }, { "database": "iPTMnet", "id": "A2AHJ4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AHJ4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 884, "end_pos": 884, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 885, "end_pos": 885, "kinase_uniprot_canonical_ac": "Q3UD01-1", "kinase_gene_name": "Atxn7l3b", "residue": "Ser", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" }, { "database": "iPTMnet", "id": "A2AHJ4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AHJ4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "start_pos": 885, "end_pos": 885, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "glycation": [], "keywords": [], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" }, { "database": "iPTMnet", "id": "A2AHJ4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AHJ4" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "pathway": [ { "id": "mmu:382236", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:382236", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z8C5-1", "protein_name": "Bromodomain and WD repeat domain-containing 3", "gene_name": "Brwd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKNTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDNSLVMEFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGNNLTSTEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQEESILDGIIRELQREQDLRLINEGDVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRRSGQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKKPSYPIQRNDYQPSCGRSLRRTQRKRQHTYLTRSNIEHNSQASSQNSGVQGDSDSSSEEDETVGTSDASAEDPVVEWQSESSSSDSSSEYSDWTADAGINLQPPKRQTRQATQKIYSSSEDENVKSSEDRQKKPKQTRKKKGGLVSMAGEPNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAENPNSSDPEEDTEMVDLDSDGPGTSSGRRAKCRGRRQSLKCNPDAWKQQCKELLSLIYEREDSEPFRQPADPHSHPVAQQQEGESSESVPPDRQDPSLSEDYQDVVDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENRIKNIISEYKSAIQSQKRRRPRYRKRLRSSSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVVYARTSSPFSSPVSDAAEGVSLYLLDDEGDGPFSPSSCSGYSRSGNSHDPGKAKSFRNRVLPAKQDHSLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKEKAHLSSSESGELGSSLSSESTSGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRRQHATGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGGRGRGGGGGRGRGRGRGGRGASRGASRTKRARVADDEFDTMFAGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1800 }, "evidence": [ { "id": "A2AHJ4", "url": "https://omabrowser.org/oma/group/A2AHJ4/", "database": "OMA" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6RI45-1", "protein_name": "Bromodomain and WD repeat-containing protein 3", "gene_name": "BRWD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQDESILDGIIRELQREQDLRLINEGDVPHLPVNRAYSVNGALRSPNMDISSSPNIRLRRHSSQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNNGVSRVQEECRTAKGDIEISLYTVEKKKKPSYTTQRNDYEPSCGRSLRRTQRKRQHTYQTRSNIEHNSQASCQNSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSESSSSDSSSEYSDWTADAGINLQPPKRQTRQTTRKICSSSDEENLKSLEERQKKPKQTRKKKGGLVSIAGEPNEEWFAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEVGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGVPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINHLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIRRRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAEERNSTDAEEDTEIVDLDSDGPGTSSGRKVKCRGRRQSLKCNPDAWKKQCKELLSLIYEREDSEPFRQPADLLSYPGHQEQEGESSESVVPERQQDSSLSEDYQDVIDTPVDFSTVKETLEAGNYGSPLEFYKDVRQIFNNSKAYTSNKKSRIYSMMLRLSALFESHIKNIISEYKSAIQSQKRRRPRYRKRLRSSSSSLSSSGAPSPKGKQKQMKLQPKNDQNTSVSHARTSSPFSSPVSDAAEGLSLYLLDDEPDGPFSSSSFGGYSRSGNSHDPGKAKSFRNRVLPVKQDHSLDGPLTNGDGREPRTGIKRKLLSASEEDENMGGEDKEKKETKEKSHLSTSESGELGSSLSSESTCGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHGNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGSRGRGGGGTRGRGRGRGGRGASRGATRAKRARIADDEFDTMFSGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1802 }, "evidence": [ { "id": "18736", "url": "http://www.informatics.jax.org/homology/18736", "database": "MGI" }, { "id": "A2AHJ4", "url": "https://omabrowser.org/oma/group/A2AHJ4/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" } ], "pmid": "21873635" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" } ], "pmid": "21873635" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A2AHJ4", "url": "https://www.uniprot.org/uniprot/A2AHJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1480, "end_pos": 1482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ] }