{ "uniprot_canonical_ac": "A2AG50-1", "uniprot_ac": "A2AG50", "uniprot_id": "MA7D2_MOUSE", "mass": { "chemical_mass": 86050.0, "monoisotopic_mass": 86050.0 }, "refseq": { "ac": "NP_001074593", "name": "MAP7 domain-containing protein 2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593" }, "gene_names": [ { "name": "Map7d2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2AG50", "id": "A2AG50" }, { "name": "1600028E09Rik; 2900002G04Rik; 5330432J06Rik; C030036K04Rik; Mtap7d2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593", "id": "NP_001074593" }, { "name": "Map7d2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593", "id": "NP_001074593" }, { "name": "Mtap7d2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2AG50", "id": "A2AG50" } ], "protein_names": [ { "name": "MAP7 domain-containing protein 2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2AG50#names_and_taxonomy", "id": "A2AG50" }, { "name": "MAP7 domain-containing protein 2 isoform 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593", "id": "NP_001074593" }, { "name": "MAP7 domain-containing protein 2; novel E-MAP-115 family protein", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593", "id": "NP_001074593" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AG50", "url": "https://www.uniprot.org/uniprot/A2AG50" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Map7d2", "url": "https://www.uniprot.org/uniprot/A2AG50", "locus": { "chromosome": "X", "start_pos": 159414572, "end_pos": 159498757, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000041020", "url": "https://www.ensembl.org/id/ENSMUSG00000041020" } ] } } ], "crossref": [ { "id": "ENSMUSG00000041020", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000041020", "database": "Bgee" }, { "id": "78283", "url": "https://www.ncbi.nlm.nih.gov/gene/78283", "database": "GeneID" }, { "id": "IPR008604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008604", "database": "InterPro" }, { "id": "mmu:78283", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:78283", "database": "KEGG Pathway" }, { "id": "1917474", "url": "http://www.informatics.jax.org/marker/MGI:1917474", "database": "MGI" }, { "id": "LNTCQEI", "url": "https://omabrowser.org/oma/group/LNTCQEI/", "database": "OMA" }, { "id": "265189at2759", "url": "http://www.orthodb.org/?query=265189at2759", "database": "OrthoDB" }, { "id": "PF05672", "url": "http://pfam.xfam.org/family/PF05672", "database": "Pfam" }, { "id": "PR_A2AG50", "url": "http://purl.obolibrary.org/obo/PR_A2AG50", "database": "PRO" }, { "id": "NP_001074593", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593", "database": "RefSeq" }, { "id": "A2AG50", "url": "https://www.uniprot.org/uniprot/A2AG50", "database": "UniProtKB" }, { "id": "A2AG50-1", "url": "https://www.uniprot.org/uniprot/A2AG50-1", "database": "UniProtKB" }, { "id": "A2AG50-2", "url": "https://www.uniprot.org/uniprot/A2AG50-2", "database": "UniProtKB" }, { "id": "A2AG50-3", "url": "https://www.uniprot.org/uniprot/A2AG50-3", "database": "UniProtKB" }, { "id": "A2AG51", "url": "https://www.uniprot.org/uniprot/A2AG51", "database": "UniProtKB" }, { "id": "A2AG51-1", "url": "https://www.uniprot.org/uniprot/A2AG51-1", "database": "UniProtKB" }, { "id": "Q8C0A6", "url": "https://www.uniprot.org/uniprot/Q8C0A6", "database": "UniProtKB" }, { "id": "Q8C0A6-1", "url": "https://www.uniprot.org/uniprot/Q8C0A6-1", "database": "UniProtKB" } ], "sequence": { "sequence": "MERSGGNGGGGGGGGGGGGGYGGSGGGGGGAGVPSEGAAKGLSLLLAKSAEAASGRASQSTPRSAGMDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKCSWAGSPGPGGRDGESENTPPLPLTLATSTPPLDTGTTTAAAESTNACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVELQPPPDVENKANKAKPVVPNKIEINVLNTCQKVSGSERAAPETFPQDIFSTGLKPVGGPVHLDVLDGKSNSLDDSTEDVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC", "length": 781, "header": "sp|A2AG50-1|MA7D2_MOUSE Isoform 1 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1" }, "isoforms": [ { "isoform_ac": "A2AG50-1", "url": "https://www.uniprot.org/uniprot/A2AG50#A2AG50-1", "sequence": { "sequence": "MERSGGNGGGGGGGGGGGGGYGGSGGGGGGAGVPSEGAAKGLSLLLAKSAEAASGRASQSTPRSAGMDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKCSWAGSPGPGGRDGESENTPPLPLTLATSTPPLDTGTTTAAAESTNACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVELQPPPDVENKANKAKPVVPNKIEINVLNTCQKVSGSERAAPETFPQDIFSTGLKPVGGPVHLDVLDGKSNSLDDSTEDVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC", "length": 781, "header": "sp|A2AG50-1|MA7D2_MOUSE Isoform 1 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1" }, "locus": { "chromosome": "X", "start_pos": 158279277, "end_pos": 158197693, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000112471", "url": "https://www.ensembl.org/id/ENSMUST00000112471" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000108090", "url": "https://www.ensembl.org/id/ENSMUSP00000108090" } ] } }, { "isoform_ac": "A2AG50-2", "url": "https://www.uniprot.org/uniprot/A2AG50#A2AG50-2", "sequence": { "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVELQPPPDVENKANKAKPVVPNKIEINVLNTCQKVSGSERAAPETFPQDIFSTGLKPVGGPVHLDVLDGKSNSLDDSTEDVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC", "length": 597, "header": "sp|A2AG50-2|MA7D2_MOUSE Isoform 2 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1" }, "locus": { "chromosome": "X", "start_pos": 158279277, "end_pos": 158242389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000043151", "url": "https://www.ensembl.org/id/ENSMUST00000043151" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000046693", "url": "https://www.ensembl.org/id/ENSMUSP00000046693" } ] } }, { "isoform_ac": "A2AG50-3", "url": "https://www.uniprot.org/uniprot/A2AG50#A2AG50-3", "sequence": { "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERM", "length": 296, "header": "sp|A2AG50-3|MA7D2_MOUSE Isoform 3 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1" }, "locus": { "chromosome": "X", "start_pos": 158269425, "end_pos": 158242389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000112470", "url": "https://www.ensembl.org/id/ENSMUST00000112470" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000108089", "url": "https://www.ensembl.org/id/ENSMUSP00000108089" } ] } }, { "isoform_ac": "A2AG51-1", "url": "https://www.uniprot.org/uniprot/A2AG50#A2AG51-1", "sequence": { "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLER", "length": 402, "header": "tr|A2AG51-1|MA7D2_MOUSE Computationally mapped isoform of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=2 CANONICAL=A2AG50-1" }, "locus": { "chromosome": "X", "start_pos": 158273774, "end_pos": 158242389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000145142", "url": "https://www.ensembl.org/id/ENSMUST00000145142" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000122106", "url": "https://www.ensembl.org/id/ENSMUSP00000122106" } ] } }, { "isoform_ac": "Q8C0A6-1", "url": "https://www.uniprot.org/uniprot/A2AG50#Q8C0A6-1", "sequence": { "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQ", "length": 74, "header": "tr|Q8C0A6-1|MA7D2_MOUSE Computationally mapped isoform of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1" }, "locus": { "chromosome": "X", "start_pos": 158253089, "end_pos": 158242389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000156172", "url": "https://www.ensembl.org/id/ENSMUST00000156172" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000119132", "url": "https://www.ensembl.org/id/ENSMUSP00000119132" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 248, "end_pos": 248, "kinase_uniprot_canonical_ac": "Q3UD01-1", "kinase_gene_name": "Atxn7l3b", "residue": "Ser", "comment": "", "evidence": [ { "database": "phospho.ELM", "id": "A2AG50", "url": "http://phospho.elm.eu.org/byAccession/A2AG50.html" }, { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" }, { "database": "PubMed", "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087" } ] } ], "glycation": [], "keywords": [], "publication": [ { "title": "Comprehensive identification of phosphorylation sites in postsynaptic density preparations.", "journal": "Mol. Cell. Proteomics", "date": "2006", "authors": "Schoepfer R., Burlingame A.L., Thalhammer A., Specht C.G., Trinidad J.C.", "evidence": [ { "database": "UniProtKB", "id": "A2AG51", "url": "https://www.uniprot.org/uniprot/A2AG51" }, { "database": "UniProtKB", "id": "A2AG50", "url": "https://www.uniprot.org/uniprot/A2AG50" }, { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "reference": [ { "type": "PubMed", "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087" } ] } ], "pathway": [ { "id": "mmu:78283", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:78283", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A4L4-1", "protein_name": "MAP7 domain-containing 2", "gene_name": "Map7d2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKCSWAGSAASGPGGRDGESENTPPLPLTLAASIPPSDTGTATAAAESTNACDKLSTSTMNLPKQTEPPMSKHLSSSIVAISYSPDRALRSPLKSSYKSSPTRTTEKKKNTLLSGVGDAGKGAMTGGEPSQMEKVKKGRGATSVSSGGLGSPLRRCEPPENISKRSSSPVKSKVTAKTYPQSPKTVKPTYIGSPVKYYFPPTPSEETLKKKAEKEKSNKEKEGATGRQTTVLPREETLEKPMADKDATEKYVADKHATEKHSATGGKAEHSAGKSTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEEQERLEKEELKRKAEEERLRIEKQEEEKKQQEEEEKRKAEEKAKEKAEEELLSKEEQEKEKQEKEKKEKAMIEKQIQAEKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVEIQPLPDVENKIKPVVPNKIEINVLNTCQKVNVSERAAPETFPQDIFSNGLKPVGGPVHPDVLDGKSNSLDDSTEEVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC", "length": 715 }, "evidence": [ { "id": "A2AG50", "url": "https://omabrowser.org/oma/group/A2AG50/", "database": "OMA" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96T17-1", "protein_name": "MAP7 domain-containing protein 2", "gene_name": "MAP7D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERGGGGSGTGSRPEGTARGTSLPGKIAEPGAVRTSQPNYRPQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKYSWGAPLAIGPGGHDACDKLSTSTMSLPKPTEPPMNKRLSSSTVAISYSPDRVFHVCPRLAPLGPLNPSYKSSPTRNIEKKKATSTSTSGAGDVGKEALSGGEASLVEKVKRGQRTATSLPVVNFGSPLRRCEFSGGIPKRPSSPVISKTATKAYPQSPKTTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVSPQVKKEDPKVGVQPAVCVEKKTKLVVPNKMEINGLNTCQEVNGVDHAAPETYPQDIFSNGLKPAGGLIHLDALDGKSNSLDDSTEEVQSMDVSPVSKEELISIPEFSPVSEMIPGVSLDQNGTGNARALQDLLDFTGPPTFPKRSSENLSLDDCNKNLIEGFNSPGQETPLNTFC", "length": 732 }, "evidence": [ { "id": "45149", "url": "http://www.informatics.jax.org/homology/45149", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A2AG50", "url": "https://www.uniprot.org/uniprot/A2AG50" } ], "pmid": "21873635" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A2AG50", "url": "https://www.uniprot.org/uniprot/A2AG50" } ], "pmid": "21873635" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" }, { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ] }