{
    "uniprot_canonical_ac": "A2AFR3-1",
    "uniprot_ac": "A2AFR3",
    "uniprot_id": "FRPD4_MOUSE",
    "mass": {
        "chemical_mass": 144978.0,
        "monoisotopic_mass": 144978.0
    },
    "refseq": {
        "ac": "NP_001028502",
        "name": "FERM and PDZ domain-containing protein 4 isoform a",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028502"
    },
    "gene_names": [
        {
            "name": "Frmpd4",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AFR3",
            "id": "A2AFR3"
        },
        {
            "name": "Frmpd4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028502",
            "id": "NP_001028502"
        },
        {
            "name": "Gm196; Pdzd10; Pdzk10; PKAP1; preso; Preso1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028502",
            "id": "NP_001028502"
        },
        {
            "name": "Gm196",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AFR3",
            "id": "A2AFR3"
        },
        {
            "name": "Kiaa0316",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AFR3",
            "id": "A2AFR3"
        },
        {
            "name": "Pdzd10",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AFR3",
            "id": "A2AFR3"
        },
        {
            "name": "Pdzk10",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AFR3",
            "id": "A2AFR3"
        }
    ],
    "protein_names": [
        {
            "name": "FERM and PDZ domain-containing protein 4",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AFR3#names_and_taxonomy",
            "id": "A2AFR3"
        },
        {
            "name": "FERM and PDZ domain-containing protein 4 isoform a",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028502",
            "id": "NP_001028502"
        },
        {
            "name": "FERM and PDZ domain-containing protein 4; PDZ domain-containing protein 10; PSD-95-interacting regulator of spine morphogenesis",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028502",
            "id": "NP_001028502"
        },
        {
            "name": "PDZ domain-containing protein 10",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AFR3#names_and_taxonomy",
            "id": "A2AFR3"
        },
        {
            "name": "PSD-95-interacting regulator of spine morphogenesis",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AFR3#names_and_taxonomy",
            "id": "A2AFR3"
        },
        {
            "name": "Preso",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AFR3#names_and_taxonomy",
            "id": "A2AFR3"
        }
    ],
    "function": [
        {
            "annotation": "Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol 4,5-bisphosphate.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AFR3",
                    "url": "https://www.uniprot.org/uniprot/A2AFR3#function"
                },
                {
                    "database": "PubMed",
                    "id": "Q14CM0",
                    "url": "https://glygen.org/publication/PubMed/Q14CM0"
                }
            ]
        },
        {
            "annotation": "The findings point to an important role of FRMPD4 in normal cognitive development and function in humans and mice, and support the hypothesis that FRMPD4 mutations cause ID by disrupting dendritic spine morphogenesis in glutamatergic neurons.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001028502",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028502"
                },
                {
                    "database": "PubMed",
                    "id": "29267967",
                    "url": "https://glygen.org/publication/PubMed/29267967"
                }
            ]
        },
        {
            "annotation": "Uncoupling the linkage between Preso and PSD-95 attenuated the stability of this complex and suppressed the regulatory effect of Preso on the NO response. In addition, phosphorylation of NMDAR by cyclin-dependent kinase 5 (CDK5) was shown to be responsible for the Preso-mediated Ca(2+) response, which was dependent on the interaction between Preso and CDK5. Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001028502",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028502"
                },
                {
                    "database": "PubMed",
                    "id": "31235685",
                    "url": "https://glygen.org/publication/PubMed/31235685"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AFR3",
                    "url": "https://www.uniprot.org/uniprot/A2AFR3"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Frmpd4",
            "url": "https://www.uniprot.org/uniprot/A2AFR3",
            "locus": {
                "chromosome": "X",
                "start_pos": 168577231,
                "end_pos": 167471309,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000049176",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000049176"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000049176",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000049176",
            "database": "Bgee"
        },
        {
            "id": "cd00201",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201",
            "database": "CDD"
        },
        {
            "id": "cd13183",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13183",
            "database": "CDD"
        },
        {
            "id": "cd14473",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473",
            "database": "CDD"
        },
        {
            "id": "333605",
            "url": "https://www.ncbi.nlm.nih.gov/gene/333605",
            "database": "GeneID"
        },
        {
            "id": "A2AFR3",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A2AFR3*",
            "database": "IntAct"
        },
        {
            "id": "IPR000299",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299",
            "database": "InterPro"
        },
        {
            "id": "IPR001202",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202",
            "database": "InterPro"
        },
        {
            "id": "IPR001478",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478",
            "database": "InterPro"
        },
        {
            "id": "IPR011993",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993",
            "database": "InterPro"
        },
        {
            "id": "IPR014352",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352",
            "database": "InterPro"
        },
        {
            "id": "IPR019748",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748",
            "database": "InterPro"
        },
        {
            "id": "IPR019749",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749",
            "database": "InterPro"
        },
        {
            "id": "IPR029071",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071",
            "database": "InterPro"
        },
        {
            "id": "IPR035963",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963",
            "database": "InterPro"
        },
        {
            "id": "IPR036020",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020",
            "database": "InterPro"
        },
        {
            "id": "IPR036034",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034",
            "database": "InterPro"
        },
        {
            "id": "IPR041779",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR041779",
            "database": "InterPro"
        },
        {
            "id": "mmu:333605",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:333605",
            "database": "KEGG Pathway"
        },
        {
            "id": "3042378",
            "url": "http://www.informatics.jax.org/marker/MGI:3042378",
            "database": "MGI"
        },
        {
            "id": "FREDKEQ",
            "url": "https://omabrowser.org/oma/group/FREDKEQ/",
            "database": "OMA"
        },
        {
            "id": "57420at2759",
            "url": "http://www.orthodb.org/?query=57420at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PF00373",
            "url": "http://pfam.xfam.org/family/PF00373",
            "database": "Pfam"
        },
        {
            "id": "PF00595",
            "url": "http://pfam.xfam.org/family/PF00595",
            "database": "Pfam"
        },
        {
            "id": "PR_A2AFR3",
            "url": "http://purl.obolibrary.org/obo/PR_A2AFR3",
            "database": "PRO"
        },
        {
            "id": "NP_001028502",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028502",
            "database": "RefSeq"
        },
        {
            "id": "XP_006528947",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006528947",
            "database": "RefSeq"
        },
        {
            "id": "XP_006528950",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006528950",
            "database": "RefSeq"
        },
        {
            "id": "A0A571BG68",
            "url": "https://www.uniprot.org/uniprot/A0A571BG68",
            "database": "UniProtKB"
        },
        {
            "id": "A0A571BG68-1",
            "url": "https://www.uniprot.org/uniprot/A0A571BG68-1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A589MR22",
            "url": "https://www.uniprot.org/uniprot/A0A589MR22",
            "database": "UniProtKB"
        },
        {
            "id": "A0A589MR22-1",
            "url": "https://www.uniprot.org/uniprot/A0A589MR22-1",
            "database": "UniProtKB"
        },
        {
            "id": "A0A589MR67",
            "url": "https://www.uniprot.org/uniprot/A0A589MR67",
            "database": "UniProtKB"
        },
        {
            "id": "A0A589MR67-1",
            "url": "https://www.uniprot.org/uniprot/A0A589MR67-1",
            "database": "UniProtKB"
        },
        {
            "id": "A2AFR3",
            "url": "https://www.uniprot.org/uniprot/A2AFR3",
            "database": "UniProtKB"
        },
        {
            "id": "A2AFR3-1",
            "url": "https://www.uniprot.org/uniprot/A2AFR3-1",
            "database": "UniProtKB"
        },
        {
            "id": "A2AFR3-2",
            "url": "https://www.uniprot.org/uniprot/A2AFR3-2",
            "database": "UniProtKB"
        },
        {
            "id": "A2AFR3-3",
            "url": "https://www.uniprot.org/uniprot/A2AFR3-3",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MDVFSFVKIPKLSSHRTKSSGWPPPSGTWGLNQVPPYGWEMMTNRDGRDYFINHMTQAIPFDDPRFDSCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEAVSAAPRERVIDLVRSCKESILLTVIQPYPSPKSAFISAAKKARLKSNPVKVRFSEEVIINGQVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRIEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQTQKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPGKKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFTEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNAGTQDTGSENKGKHNLLGPDWNCMPQMTTFIGEGEQEAQITYIDSKQKTVEMTDSTLCPKEHRHLYIDNSYSSDELNQPLTQPGDAPCEADYRSLAQRSLLTLSGPDTLKKAQESPRGAKVSFIFGDLALDDGMSPPTIGYERMLEENPEMLEKQRNLYISSANDMKNLDLTPDTDSIQFVANSVYANIGDVKNFEAPEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVGEMNQPAILDLSGSSDDIIDLTTLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDTQSQATSFHEDKEQGSSLQNEEIPVSLIDAVPTSAEGKCEKGLDPAVVSTLEALEALSEEQQKSENSGVAILRAYSPESSSDSGNETNSSEMTEGSELAAAQKQSESLSRMFLATHEGYHPLAEEQTEFPTSKAPSVGLPPKSSHGLAARPATDLPPKVVPSKQILHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLPEGEGKSPLSGNIPGKKQQGTKIAEIEEDTKGKAGTVSSRDNPHLSTFNLERTAFRKDSQRWYVASDGGVVEKSGMEAPAMKVFPRGPGLGNREAEGKEDGTVEGGADDASVLGQGDRFLTDMACVASAKDLDNPEDTDSPSCDHATKLSEAEDNVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDTGCGPGSSSSACATPVESPLCPSMGKHMIPDASGKGGRYISPEERAPGHPNHGATFEELHPQTEGMCPRMTVPALHTAINADPLFGTLRDGCHRLPKIKETTV",
        "length": 1320,
        "header": "sp|A2AFR3-1|FRPD4_MOUSE Isoform 1 of FERM and PDZ domain-containing protein 4  OS=Mus musculus OX=10090 GN=Frmpd4 PE=1 SV=1 CANONICAL=A2AFR3-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A571BG68-1",
            "url": "https://www.uniprot.org/uniprot/A2AFR3#A0A571BG68-1",
            "sequence": {
                "sequence": "MEEDLEGENWSTFSIPWGFGKAAEDNREHVCRHRTKSSGWPPPSGTWGLNQVPPYGWEMMTNRDGRDYFINHMTQAIPFDDPRFDSCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEAVSAAPRERVIDLVRSCKESILLTVIQPYPSPKSAFISAAKKARLKSNPVKVRFSEEVIINGQVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRIEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQTQKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPGKKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFTEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNAGTQDTGSENKGKHNLLGPDWNCMPQMTTFIGEGEQEAQITYIDSKQKTVEMTDSTLCPKEHRHLYIDNSYSSDELNQPLTQPGDAPCEADYRSLAQRSLLTLSGPDTLKKAQESPRGAKVSFIFGDLALDDGMSPPTIGYERMLEENPEMLEKQRNLYISSANDMKNLDLTPDTDSIQFVANSVYANIGDVKNFEAPEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVGEMNQPAILDLSGSSDDIIDLTTLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDTQSQATSFHEDKEQGSSLQNEEIPVSLIDAVPTSAEGKCEKGLDPAVVSTLEALEALSEEQQKSENSGVAILRAYSPESSSDSGNETNSSEMTEGSELAAAQKQSESLSRMFLATHEGYHPLAEEQTEFPTSKAPSVGLPPKSSHGLAARPATDLPPKVVPSKQILHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLPEGEGKSPLSGNIPGKKQQGTKIAEIEEDTKGKAGTVSSRDNPHLSTFNLERTAFRKDSQRWYVASDGGVVEKSGMEAPAMKVFPRGPGLGNREAEGKEDGTVEGGADDASVLGQGDRFLTDMACVASAKDLDNPEDTDSPSCDHATKLSEAEDNVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDTGCGPGSSSSACATPVESPLCPSMGKHMIPDASGKGGRYISPEERAPGHPNHGATFEELHPQTEGMCPRMTVPALHTAINADPLFGTLRDGCHRLPKIKETTALTEPGKERQGGMPSAWSPHPEADPILLPSNIHLESKVPSPNQDPNDFSQGIQAFGEAVSWWPADLRGGSPRTPPSQRALRHSSRILSGPVGLETFQERTKGVVSLKYPGITEAQEVSSERRAELPLGKKLTKSFSQSSMHFISEGKFHKRSPMSHKDSKVYRTLPLRKLESSNWRCRGPFSYCFLNQGQDEDGDEDEEEGEATLQVSCLYRPQITQAMSEPGNSSLVVGLQKQGEELSRGTALKVWTEDPDGPDDLDFSSLAFDARIARINALKANTYGMPDGFLEAQNDANELLCLVRATKARKEESRPETYDLTLSQYKQLLSIESRQLGSACRKMAMAEKSPEEMLLAMSSSFQVLCCLTEACMRLVKVVNTETQRQEIVAKIDEVVINYICLLKAAEAATGKTTGDPNIGLSMRHSTTMAALVSTLTRSLKMLLNK",
                "length": 1778,
                "header": "tr|A0A571BG68-1|A0A571BG68_MOUSE Computationally mapped isoform of FERM and PDZ domain-containing protein 4  OS=Mus musculus OX=10090 GN=Frmpd4 PE=1 SV=1 CANONICAL=A2AFR3-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 167231038,
                "end_pos": 166256972,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000238709",
                        "url": "https://www.ensembl.org/id/ENSMUST00000238709"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000158713",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000158713"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A589MR22-1",
            "url": "https://www.uniprot.org/uniprot/A2AFR3#A0A589MR22-1",
            "sequence": {
                "sequence": "MDVFSFVKIPKLSSHRTKSSGWPPPSGTWGLNQVPPYGWEMMTNRDGRDYFINHMTQAIPFDDPRFDSCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEAVSAAPRERVIDLVRSCKESILLTVIQPYPSPKSAFISAAKKARLKSNPVKVRFSEEVIINGQVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRIEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQTQKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPGKKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFTEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNAGTQDTGSENKGKHNLLGPDWNCMPQMTTFIGEGEQEAQITYIDSKQKTVEMTDSTLCPKEHRHLYIDNSYSSDELNQPLTQPGDAPCEADYRSLAQRSLLTLSGPDTLKKAQESPRGAKVSFIFGDLALDDGMSPPTIGYERMLEENPEMLEKQRNLYISSANDMKNLDLTPDTDSIQFVANSVYANIGDVKNFEAPEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVGEMNQPAILDLSGSSDDIIDLTTLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDTQSQATSFHEDKEQGSSLQNEEIPVSLIDAVPTSAEGKCEKGLDPAVVSTLEALEALSEEQQKSENSGVAILRAYSPESSSDSGNETNSSEMTEGSELAAAQKQSESLSRMFLATHEGYHPLAEEQTEFPTSKAPSVGLPPKSSHGLAARPATDLPPKVVPSKQILHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLPEGEGKSPLSGNIPGKKQQGTKIAEIEEDTKGKAGTVSSRDNPHLSTFNLERTAFRKDSQRWYVASDGGVVEKSGMEAPAMKVFPRGPGLGNREAEGKEDGTVEGGADDASVLGQGDRFLTDMACVASAKDLDNPEDTDSPSCDHATKLSEAEDNVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDTGCGPGSSSSACATPVESPLCPSMGKHMIPDASGKGGRYISPEERAPGHPNHGATFEELHPQTEGMCPRMTVPALHTAINADPLFGTLRDGCHRLPKIKETTALTEPGKERQGGMPSAWSPHPEADPILLPSNIHLESKVPSPNQDPNDFSQGIQAFGEAVSWWPADLRGGSPRTPPSQRALRHSSRILSGPVGLETFQERTKGVVSLKYPGITEAQEVSSERRAELPLGKKLTKSFSQSSMHFISEGKFHKRSPMSHKDSKVYRTLPLRKLESSNWRCRGPFSYCFLNQGQDEDGDEDEEEGEATLQVSCLYRPQITQAMSEPGNSSLVVGLQKQGEELSRGTALKVWTEDPDGPDDLDFSSLAFDARIARINALKANTYGMPDGFLEAQNDANELLCLVRATKARKEESRPETYDLTLSQYKQLLSIESRQLGSACRKMAMAEKSPEEMLLAMSSSFQVLCCLTEACMRLVKVVNTETQRQEIVAKIDEVVINYICLLKAAEAATGKTTGDPNIGLSMRHSTTMAALVSTLTRSLKMLLNK",
                "length": 1760,
                "header": "tr|A0A589MR22-1|FRPD4_MOUSE Computationally mapped isoform of FERM and PDZ domain-containing protein 4  OS=Mus musculus OX=10090 GN=Frmpd4 PE=1 SV=1 CANONICAL=A2AFR3-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 166905822,
                "end_pos": 166256972,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000112146",
                        "url": "https://www.ensembl.org/id/ENSMUST00000112146"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000107774",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000107774"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A589MR67-1",
            "url": "https://www.uniprot.org/uniprot/A2AFR3#A0A589MR67-1",
            "sequence": {
                "sequence": "MEEDLEGENWSTFSIPWGFGKAAEDNREHVCRHSAVL",
                "length": 37,
                "header": "tr|A0A589MR67-1|A0A589MR67_MOUSE Computationally mapped isoform of FERM and PDZ domain-containing protein 4  OS=Mus musculus OX=10090 GN=Frmpd4 PE=4 SV=1 CANONICAL=A2AFR3-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 167231038,
                "end_pos": 166680619,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000112147",
                        "url": "https://www.ensembl.org/id/ENSMUST00000112147"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000107775",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000107775"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2AFR3-1",
            "url": "https://www.uniprot.org/uniprot/A2AFR3#A2AFR3-1",
            "sequence": {
                "sequence": "MDVFSFVKIPKLSSHRTKSSGWPPPSGTWGLNQVPPYGWEMMTNRDGRDYFINHMTQAIPFDDPRFDSCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEAVSAAPRERVIDLVRSCKESILLTVIQPYPSPKSAFISAAKKARLKSNPVKVRFSEEVIINGQVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRIEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQTQKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPGKKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFTEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNAGTQDTGSENKGKHNLLGPDWNCMPQMTTFIGEGEQEAQITYIDSKQKTVEMTDSTLCPKEHRHLYIDNSYSSDELNQPLTQPGDAPCEADYRSLAQRSLLTLSGPDTLKKAQESPRGAKVSFIFGDLALDDGMSPPTIGYERMLEENPEMLEKQRNLYISSANDMKNLDLTPDTDSIQFVANSVYANIGDVKNFEAPEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVGEMNQPAILDLSGSSDDIIDLTTLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDTQSQATSFHEDKEQGSSLQNEEIPVSLIDAVPTSAEGKCEKGLDPAVVSTLEALEALSEEQQKSENSGVAILRAYSPESSSDSGNETNSSEMTEGSELAAAQKQSESLSRMFLATHEGYHPLAEEQTEFPTSKAPSVGLPPKSSHGLAARPATDLPPKVVPSKQILHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLPEGEGKSPLSGNIPGKKQQGTKIAEIEEDTKGKAGTVSSRDNPHLSTFNLERTAFRKDSQRWYVASDGGVVEKSGMEAPAMKVFPRGPGLGNREAEGKEDGTVEGGADDASVLGQGDRFLTDMACVASAKDLDNPEDTDSPSCDHATKLSEAEDNVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDTGCGPGSSSSACATPVESPLCPSMGKHMIPDASGKGGRYISPEERAPGHPNHGATFEELHPQTEGMCPRMTVPALHTAINADPLFGTLRDGCHRLPKIKETTV",
                "length": 1320,
                "header": "sp|A2AFR3-1|FRPD4_MOUSE Isoform 1 of FERM and PDZ domain-containing protein 4  OS=Mus musculus OX=10090 GN=Frmpd4 PE=1 SV=1 CANONICAL=A2AFR3-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 166905822,
                "end_pos": 166258297,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000112149",
                        "url": "https://www.ensembl.org/id/ENSMUST00000112149"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000107777",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000107777"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2AFR3-2",
            "url": "https://www.uniprot.org/uniprot/A2AFR3#A2AFR3-2",
            "sequence": {
                "sequence": "MMTNRDGRDYFINHMTQAIPFDDPRFDSCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEAVSAAPRERVIDLVRSCKESILLTVIQPYPSPKSAFISAAKKARLKSNPVKVRFSEEVIINGQVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRIEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQTQKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPGKKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFTEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNAGTQDTGSENKGKHNLLGPDWNCMPQMTTFIGEGEQEAQITYIDSKQKTVEMTDSTLCPKEHRHLYIDNSYSSDELNQPLTQPGDAPCEADYRSLAQRSLLTLSGPDTLKKAQESPRGAKVSFIFGDLALDDGMSPPTIGYERMLEENPEMLEKQRNLYISSANDMKNLDLTPDTDSIQFVANSVYANIGDVKNFEAPEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVGEMNQPAILDLSGSSDDIIDLTTLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDTQSQATSFHEDKEQGSSLQNEEIPVSLIDAVPTSAEGKCEKGLDPAVVSTLEALEALSEEQQKSENSGVAILRAYSPESSSDSGNETNSSEMTEGSELAAAQKQSESLSRMFLATHEGYHPLAEEQTEFPTSKAPSVGLPPKSSHGLAARPATDLPPKVVPSKQILHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLPEGEGKSPLSGNIPGKKQQGTKIAEIEEDTKGKAGTVSSRDNPHLSTFNLERTAFRKDSQRWYVASDGGVVEKSGMEAPAMKVFPRGPGLGNREAEGKEDGTVEGGADDASVLGQGDRFLTDMACVASAKDLDNPEDTDSPSCDHATKLSEAEDNVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDTGCGPGSSSSACATPVESPLCPSMGKHMIPDASGKGGRYISPEERAPGHPNHGATFEELHPQTEGMCPRMTVPALHTAINADPLFGTLRDGCHRLPKIKETTV",
                "length": 1280,
                "header": "sp|A2AFR3-2|FRPD4_MOUSE Isoform 2 of FERM and PDZ domain-containing protein 4  OS=Mus musculus OX=10090 GN=Frmpd4 PE=1 SV=1 CANONICAL=A2AFR3-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 166512052,
                "end_pos": 166258297,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000238211",
                        "url": "https://www.ensembl.org/id/ENSMUST00000238211"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000158917",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000158917"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2AFR3-3",
            "url": "https://www.uniprot.org/uniprot/A2AFR3#A2AFR3-3",
            "sequence": {
                "sequence": "MRSHSCHRTKSSGWPPPSGTWGLNQVPPYGWEMMTNRDGRDYFINHMTQAIPFDDPRFDSCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEAVSAAPRERVIDLVRSCKESILLTVIQPYPSPKSAFISAAKKARLKSNPVKVRFSEEVIINGQVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRIEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQTQKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPGKKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFTEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNAGTQDTGSENKGKHNLLGPDWNCMPQMTTFIGEGEQEAQITYIDSKQKTVEMTDSTLCPKEHRHLYIDNSYSSDELNQPLTQPGDAPCEADYRSLAQRSLLTLSGPDTLKKAQESPRGAKVSFIFGDLALDDGMSPPTIGYERMLEENPEMLEKQRNLYISSANDMKNLDLTPDTDSIQFVANSVYANIGDVKNFEAPEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVGEMNQPAILDLSGSSDDIIDLTTLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDTQSQATSFHEDKEQGSSLQNEEIPVSLIDAVPTSAEGKCEKGLDPAVVSTLEALEALSEEQQKSENSGVAILRAYSPESSSDSGNETNSSEMTEGSELAAAQKQSESLSRMFLATHEGYHPLAEEQTEFPTSKAPSVGLPPKSSHGLAARPATDLPPKVVPSKQILHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLPEGEGKSPLSGNIPGKKQQGTKIAEIEEDTKGKAGTVSSRDNPHLSTFNLERTAFRKDSQRWYVASDGGVVEKSGMEAPAMKVFPRGPGLGNREAEGKEDGTVEGGADDASVLGQGDRFLTDMACVASAKDLDNPEDTDSPSCDHATKLSEAEDNVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDTGCGPGSSSSACATPVESPLCPSMGKHMIPDASGKGGRYISPEERAPGHPNHGATFEELHPQTEGMCPRMTVPALHTAINADPLFGTLRDGCHRLPKIKETTV",
                "length": 1312,
                "header": "sp|A2AFR3-3|FRPD4_MOUSE Isoform 3 of FERM and PDZ domain-containing protein 4  OS=Mus musculus OX=10090 GN=Frmpd4 PE=1 SV=1 CANONICAL=A2AFR3-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 166680554,
                "end_pos": 166258297,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000239138",
                        "url": "https://www.ensembl.org/id/ENSMUST00000239138"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000159190",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000159190"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.",
            "journal": "J. Neurosci.",
            "date": "2008",
            "authors": "Choi J., Kim K., Yang J., Lee H.W., Kim E., Kim H., Choi S.Y., Eom S.H., Kang G.B., Na M., Shin H.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AFR3",
                    "url": "https://www.uniprot.org/uniprot/A2AFR3"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19118189",
                    "url": "https://glygen.org/publication/PubMed/19118189"
                }
            ]
        },
        {
            "title": "FRMPD4 mutations cause X-linked intellectual disability and disrupt dendritic spine morphogenesis.",
            "journal": "Human molecular genetics",
            "date": "2018",
            "authors": "Piard J, Hu JH, Campeau PM, Rzonca S, Van Esch H, Vincent E, Han M, Rossignol E, Castaneda J, Chelly J, Skinner C, Kalscheuer VM, Wang R, Lemyre E, Kosinska J, Stawinski P, Bal J, Hoffman DA, Schwartz CE, Van Maldergem L, Wang T, Worley PF",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001028502",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028502"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "29267967",
                    "url": "https://glygen.org/publication/PubMed/29267967"
                }
            ]
        },
        {
            "title": "Preso regulates NMDA receptor-mediated excitotoxicity via modulating nitric oxide and calcium responses after traumatic brain injury.",
            "journal": "Cell death & disease",
            "date": "2019",
            "authors": "Luo P, Li X, Wu X, Dai S, Yang Y, Xu H, Jing D, Rao W, Xu H, Gao X, Fei Z, Lu H",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001028502",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028502"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "31235685",
                    "url": "https://glygen.org/publication/PubMed/31235685"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:333605",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:333605",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D4A3K7-1",
            "protein_name": "FERM and PDZ domain-containing 4",
            "gene_name": "Frmpd4",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MTQAIPFDDPRFDSCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEPVSAAPRERVIDLVRSCKESILFTVIQPYPSPKSAFISAAKKARLKSNPVKVRFSEEVIINGQVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRTEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQTQKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPGKKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFTEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNAGTQDTGTENKGKHNLLGPDWNCMPQMTTFIGEGEQEAQITYIDSKQKAVEMTDSTLCPKEHRHLYIDNTYSSDELSQPLTQPGDAPCEADYRSLAQRSLLTLSGPDTLKKAQESPRGAKVSFIFGDLALDDGMSPPTLGYERMLDENPEMLEKQRNLYISSANDMKNLDLTPDTDSIQFVANSVYANIGDVKNFEAPEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVSEINQPAILDLSGSSDDIIDLTTLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDTQSQATSFHENKEQGSSLQNEEIPVSLIDAVPTSAEGKCEKGLDPTVVSTLEALEALSEEQQKSENSGVAILRAYSPESSSDSGNETNSSEMTEGSELAAAQKQSESLSRMFLATHEGYHPLAEEQTEFPTSKTPSVGLPPKSSHGLAARPATDLPPKVVPSKQILHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLAEGEGKCPLSGNVPGKKQQGTKIAETEEDTKGKVGTVSSRDNPHLSTFNLERTAFRKDSQRWYVASDGGVVEKSGVEAPAMKAFPRGPGLGNREAEGKEDGTMEGEADDASGLGQGERFLSDMACVASAKDLDNPEDTDSPTCDHATKLPEAEDNVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDTGCGPGSSSSACATPVESPLCPSMGKHLIPDASGKGGSYISPEERVAGHPNHGATFKELHPQTEGMCPRMTVPALHTAINADPLFGTLRDGCHRLPKIKETTALTEPGKERQGGMPSAWSPHPEADPILLPSNIHLESKVPSPNQDPNDFSQGNQAFGEAVSWRPADLRGGSLRTPPSQRALRHSSSILSGPVGLETFQEGTKGVVSLKYPGITEAQEASSERRAELPLGKKLTKSFSQSSMHFISEGKFHKRSPMSHKDSKVYRTLPLRKLESSNWRCRGPFSYCFLNQGQDEDGDEDEEGEATLQVSCLYRPHITQGMPETSNSSLAVGLQKQGEELSRGTVLKDWTEDPDGPDDLDFSSLAFDARIARINALKANTYGMPDGFLEAQNDANELLCLVRATKAKREESRPEAYDLTLSQYKQLLSIESRQLGSACRKMAMAEKSPEEMLLAMSSSFQVLCCLTEACMRLVKVVNSETQRQEIVEKIDEVVINYICLLKAAEAATGKTTGDPSIGLSMRHSTTMAALVSTLTRSLKMLLNK",
                "length": 1705
            },
            "evidence": [
                {
                    "id": "45843",
                    "url": "http://www.informatics.jax.org/homology/45843",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q14CM0-1",
            "protein_name": "FERM and PDZ domain-containing protein 4",
            "gene_name": "FRMPD4",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MDVFSFVKIAKLSSHRTKSSGWPPPSGTWGLSQVPPYGWEMTANRDGRDYFINHMTQAIPFDDPRLESCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEPVSAAPRERVIDLVRSCKESILLTVIQPYPSPKSAFISAAKKARLKSNPVKVRFSEEVIINGQVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRTEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQTQKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPGKKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFSEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNTATQETGPENKGKHNLLGPDWNCIPQMTTFIGEGEQEAQITYIDSKQKTVEITDSTMCPKEHRHLYIDNAYSSDGLNQQLSQPGEAPCEADYRSLAQRSLLTLSGPETLKKAQESPRGAKVSFIFGDFALDDGISPPTLGYETLLDEGPEMLEKQRNLYIGSANDMKGLDLTPEAEGIQFVENSVYANIGDVKSFQAAEGIEEPLLHDICYAENTDDAEDEDEVSCEEDLVVGEMNQPAILNLSGSSDDIIDLTSLPPPEGDDNEDDFLLRSLNMAIAAPPPGFRDSSDEEDSQSQAASFPEDKEKGSSLQNDEIPVSLIDAVPTSAEGKCEKGLDNAVVSTLGALEALSVSEEQQTSDNSGVAILRAYSPESSSDSGNETNSSEMTESSELATAQKQSENLSRMFLATHEGYHPLAEEQTEFPASKTPAGGLPPKSSHALAARPATDLPPKVVPSKQLLHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLADGEGKAPPNGNTTGKKQQGTKTAEMEEEASGKFGTVSSRDSQHLSTFNLERTAFRKDSQRWYVATEGGMAEKSGLEAATGKTFPRASGLGAREAEGKEEGAPDGETSDGSGLGQGDRFLTDVTCASSAKDLDNPEDADSSTCDHPSKLPEADESVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDAGCGTGSSGSACATPVESPLCPSLGKHLIPDASGKGVNYIPSEERAPGLPNHGATFKELHPQTEGMCPRMTVPALHTAINTEPLFGTLRDGCHRLPKIKETTV",
                "length": 1322
            },
            "evidence": [
                {
                    "id": "45843",
                    "url": "http://www.informatics.jax.org/homology/45843",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 5,
                "go_terms": [
                    {
                        "name": "glutamatergic synapse",
                        "id": "GO:0098978",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AFR3",
                                "url": "https://www.uniprot.org/uniprot/A2AFR3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoskeleton",
                        "id": "GO:0005856",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AFR3",
                                "url": "https://www.uniprot.org/uniprot/A2AFR3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "postsynaptic density",
                        "id": "GO:0014069",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AFR3",
                                "url": "https://www.uniprot.org/uniprot/A2AFR3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dendritic spine",
                        "id": "GO:0043197",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AFR3",
                                "url": "https://www.uniprot.org/uniprot/A2AFR3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein-containing complex",
                        "id": "GO:0032991",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AFR3",
                                "url": "https://www.uniprot.org/uniprot/A2AFR3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "phosphatidylinositol-4,5-bisphosphate binding",
                        "id": "GO:0005546",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AFR3",
                                "url": "https://www.uniprot.org/uniprot/A2AFR3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "postsynaptic actin cytoskeleton organization",
                        "id": "GO:0098974",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098974",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AFR3",
                                "url": "https://www.uniprot.org/uniprot/A2AFR3"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of synapse structural plasticity",
                        "id": "GO:0051835",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051835",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AFR3",
                                "url": "https://www.uniprot.org/uniprot/A2AFR3"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 907,
            "end_pos": 909,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 910,
            "end_pos": 912,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}