{
    "uniprot_canonical_ac": "A2AF33-1",
    "uniprot_ac": "A2AF33",
    "uniprot_id": "A2AF33_MOUSE",
    "mass": {
        "chemical_mass": 5249.0,
        "monoisotopic_mass": 5249.0
    },
    "refseq": {
        "ac": "NP_001075452",
        "name": "thymosin beta-like",
        "summary": "This gene is part of tandem duplication; the other copy of this gene is about 1.5 kb away. Readthrough transcripts that include two exons transcribed from each gene exist. [provided by RefSeq, Jul 2008].",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075452"
    },
    "gene_names": [
        {
            "name": "Tmsb15b1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AF33",
            "id": "A2AF33"
        },
        {
            "name": "Tm15b",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075452",
            "id": "NP_001075452"
        },
        {
            "name": "Tmsb15b1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075452",
            "id": "NP_001075452"
        }
    ],
    "protein_names": [
        {
            "name": "Thymosin beta",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AF33#names_and_taxonomy",
            "id": "A2AF33"
        },
        {
            "name": "thymosin beta-like",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075452",
            "id": "NP_001075452"
        }
    ],
    "function": [
        {
            "annotation": "Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AF33",
                    "url": "https://www.uniprot.org/uniprot/A2AF33#function"
                },
                {
                    "database": "PubMed",
                    "id": "PIRNR001828",
                    "url": "https://glygen.org/publication/PubMed/PIRNR001828"
                }
            ]
        },
        {
            "annotation": "This gene is part of tandem duplication; the other copy of this gene is about 1.5 kb away. Readthrough transcripts that include two exons transcribed from each gene exist. [provided by RefSeq, Jul 2008].",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001075452",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075452"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AF33",
                    "url": "https://www.uniprot.org/uniprot/A2AF33"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Tmsb15b1",
            "url": "https://www.uniprot.org/uniprot/A2AF33",
            "locus": {
                "chromosome": "X",
                "start_pos": 136976874,
                "end_pos": 136974022,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000089768",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000089768"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000089768",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000089768",
            "database": "Bgee"
        },
        {
            "id": "666244",
            "url": "https://www.ncbi.nlm.nih.gov/gene/666244",
            "database": "GeneID"
        },
        {
            "id": "IPR001152",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001152",
            "database": "InterPro"
        },
        {
            "id": "IPR038386",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038386",
            "database": "InterPro"
        },
        {
            "id": "mmu:666244",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:666244",
            "database": "KEGG Pathway"
        },
        {
            "id": "3843059",
            "url": "http://www.informatics.jax.org/marker/MGI:3843059",
            "database": "MGI"
        },
        {
            "id": "754086at2759",
            "url": "http://www.orthodb.org/?query=754086at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PTHR12021",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12021",
            "database": "PANTHER"
        },
        {
            "id": "PF01290",
            "url": "http://pfam.xfam.org/family/PF01290",
            "database": "Pfam"
        },
        {
            "id": "NP_001075452",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075452",
            "database": "RefSeq"
        },
        {
            "id": "A2AF33",
            "url": "https://www.uniprot.org/uniprot/A2AF33",
            "database": "UniProtKB"
        },
        {
            "id": "A2AF33-1",
            "url": "https://www.uniprot.org/uniprot/A2AF33-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MSDKPDLSEVETFDKSKLKKTNTEVKNTLPSNETIQQEKEHNERT",
        "length": 45,
        "header": "tr|A2AF33-1|A2AF33_MOUSE Isoform 1 of Thymosin beta  OS=Mus musculus OX=10090 GN=Tmsb15b1 PE=1 SV=1 CANONICAL=A2AF33-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A2AF33-1",
            "url": "https://www.uniprot.org/uniprot/A2AF33#A2AF33-1",
            "sequence": {
                "sequence": "MSDKPDLSEVETFDKSKLKKTNTEVKNTLPSNETIQQEKEHNERT",
                "length": 45,
                "header": "tr|A2AF33-1|A2AF33_MOUSE Isoform 1 of Thymosin beta  OS=Mus musculus OX=10090 GN=Tmsb15b1 PE=1 SV=1 CANONICAL=A2AF33-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 135876246,
                "end_pos": 135874954,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000113071",
                        "url": "https://www.ensembl.org/id/ENSMUST00000113071"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000108694",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000108694"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:666244",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:666244",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "actin monomer binding",
                        "id": "GO:0003785",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AF33",
                                "url": "https://www.uniprot.org/uniprot/A2AF33"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AF33",
                                "url": "https://www.uniprot.org/uniprot/A2AF33"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "cytoskeleton",
                        "id": "GO:0005856",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AF33",
                                "url": "https://www.uniprot.org/uniprot/A2AF33"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "actin filament organization",
                        "id": "GO:0007015",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AF33",
                                "url": "https://www.uniprot.org/uniprot/A2AF33"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of cell migration",
                        "id": "GO:0030334",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AF33",
                                "url": "https://www.uniprot.org/uniprot/A2AF33"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "sequestering of actin monomers",
                        "id": "GO:0042989",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042989",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AF33",
                                "url": "https://www.uniprot.org/uniprot/A2AF33"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 32,
            "end_pos": 34,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": []
}