{
    "uniprot_canonical_ac": "A2AEH9-1",
    "uniprot_ac": "A2AEH9",
    "uniprot_id": "A2AEH9_MOUSE",
    "mass": {
        "chemical_mass": 8909.0,
        "monoisotopic_mass": 8909.0
    },
    "refseq": {
        "ac": "XP_006528691",
        "name": "thymosin beta-15A isoform X1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006528691"
    },
    "gene_names": [
        {
            "name": "Tmsb15a",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AEH9",
            "id": "A2AEH9"
        },
        {
            "name": "1700129I15Rik; Tb15a; Tmsbl1; Tmsl8",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084382",
            "id": "NP_084382"
        },
        {
            "name": "Tmsb15a",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084382",
            "id": "NP_084382"
        }
    ],
    "protein_names": [
        {
            "name": "Thymosin beta 15a",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2AEH9#names_and_taxonomy",
            "id": "A2AEH9"
        },
        {
            "name": "thymosin beta-15A isoform X1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006528691",
            "id": "XP_006528691"
        },
        {
            "name": "thymosin beta-15A",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084382",
            "id": "NP_084382"
        },
        {
            "name": "thymosin-like 8; thymosin beta-like protein 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084382",
            "id": "NP_084382"
        }
    ],
    "function": [
        {
            "annotation": "Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9D2R9",
                    "url": "https://www.uniprot.org/uniprot/Q9D2R9#function"
                },
                {
                    "database": "PubMed",
                    "id": "PIRNR001828",
                    "url": "https://glygen.org/publication/PubMed/PIRNR001828"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AEH9",
                    "url": "https://www.uniprot.org/uniprot/A2AEH9"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Tmsb15a",
            "url": "https://www.uniprot.org/uniprot/A2AEH9",
            "locus": {
                "chromosome": "X",
                "start_pos": 135725261,
                "end_pos": 135718667,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000060726",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000060726"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000060726",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000060726",
            "database": "Bgee"
        },
        {
            "id": "78478",
            "url": "https://www.ncbi.nlm.nih.gov/gene/78478",
            "database": "GeneID"
        },
        {
            "id": "IPR001152",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001152",
            "database": "InterPro"
        },
        {
            "id": "IPR038386",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038386",
            "database": "InterPro"
        },
        {
            "id": "mmu:78478",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:78478",
            "database": "KEGG Pathway"
        },
        {
            "id": "1925728",
            "url": "http://www.informatics.jax.org/marker/MGI:1925728",
            "database": "MGI"
        },
        {
            "id": "1640382at2759",
            "url": "http://www.orthodb.org/?query=1640382at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PTHR12021",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12021",
            "database": "PANTHER"
        },
        {
            "id": "PF01290",
            "url": "http://pfam.xfam.org/family/PF01290",
            "database": "Pfam"
        },
        {
            "id": "NP_084382",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084382",
            "database": "RefSeq"
        },
        {
            "id": "XP_006528691",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006528691",
            "database": "RefSeq"
        },
        {
            "id": "A2AEH9",
            "url": "https://www.uniprot.org/uniprot/A2AEH9",
            "database": "UniProtKB"
        },
        {
            "id": "A2AEH9-1",
            "url": "https://www.uniprot.org/uniprot/A2AEH9-1",
            "database": "UniProtKB"
        },
        {
            "id": "Q9D2R9",
            "url": "https://www.uniprot.org/uniprot/Q9D2R9",
            "database": "UniProtKB"
        },
        {
            "id": "Q9D2R9-1",
            "url": "https://www.uniprot.org/uniprot/Q9D2R9-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MTHWYCKGSISLALKLTEDRAVGLIGGAVSLIVKMGDRPDLSEVERFDKSKLKKTITEVKNTLPSKETIEQEKEFVKRS",
        "length": 79,
        "header": "tr|A2AEH9-1|A2AEH9_MOUSE Isoform 1 of Thymosin beta 15a  OS=Mus musculus OX=10090 GN=Tmsb15a PE=3 SV=1 CANONICAL=A2AEH9-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A2AEH9-1",
            "url": "https://www.uniprot.org/uniprot/A2AEH9#A2AEH9-1",
            "sequence": {
                "sequence": "MTHWYCKGSISLALKLTEDRAVGLIGGAVSLIVKMGDRPDLSEVERFDKSKLKKTITEVKNTLPSKETIEQEKEFVKRS",
                "length": 79,
                "header": "tr|A2AEH9-1|A2AEH9_MOUSE Isoform 1 of Thymosin beta 15a  OS=Mus musculus OX=10090 GN=Tmsb15a PE=3 SV=1 CANONICAL=A2AEH9-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 134624117,
                "end_pos": 134619468,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000113154",
                        "url": "https://www.ensembl.org/id/ENSMUST00000113154"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000108779",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000108779"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q9D2R9-1",
            "url": "https://www.uniprot.org/uniprot/A2AEH9#Q9D2R9-1",
            "sequence": {
                "sequence": "MGDRPDLSEVERFDKSKLKKTITEVKNTLPSKETIEQEKEFVKRS",
                "length": 45,
                "header": "tr|Q9D2R9-1|A2AEH9_MOUSE Computationally mapped isoform of Thymosin beta 15a  OS=Mus musculus OX=10090 GN=Tmsb15a PE=3 SV=1 CANONICAL=A2AEH9-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 134620514,
                "end_pos": 134619468,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000073674",
                        "url": "https://www.ensembl.org/id/ENSMUST00000073674"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000073355",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000073355"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:78478",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:78478",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A2AF31-1",
            "protein_name": "Thymosin beta",
            "gene_name": "Tmsb15b2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSDKPDLSEVETFDKAKLKKTNTEVKNTLPSKETIQQEKEHNERT",
                "length": 45
            },
            "evidence": [
                {
                    "id": "116060",
                    "url": "http://www.informatics.jax.org/homology/116060",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P20065-1",
            "protein_name": "Thymosin beta-4",
            "gene_name": "Tmsb4x",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MLLPATMSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES",
                "length": 50
            },
            "evidence": [
                {
                    "id": "116060",
                    "url": "http://www.informatics.jax.org/homology/116060",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q6ZWY8-1",
            "protein_name": "Thymosin beta-10",
            "gene_name": "Tmsb10",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS",
                "length": 44
            },
            "evidence": [
                {
                    "id": "116060",
                    "url": "http://www.informatics.jax.org/homology/116060",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "actin monomer binding",
                        "id": "GO:0003785",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AEH9",
                                "url": "https://www.uniprot.org/uniprot/A2AEH9"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AEH9",
                                "url": "https://www.uniprot.org/uniprot/A2AEH9"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "cytoskeleton",
                        "id": "GO:0005856",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AEH9",
                                "url": "https://www.uniprot.org/uniprot/A2AEH9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "actin filament organization",
                        "id": "GO:0007015",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AEH9",
                                "url": "https://www.uniprot.org/uniprot/A2AEH9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of cell migration",
                        "id": "GO:0030334",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AEH9",
                                "url": "https://www.uniprot.org/uniprot/A2AEH9"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "sequestering of actin monomers",
                        "id": "GO:0042989",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042989",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AEH9",
                                "url": "https://www.uniprot.org/uniprot/A2AEH9"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}