{
    "uniprot_canonical_ac": "A2ACJ2-1",
    "uniprot_ac": "A2ACJ2",
    "uniprot_id": "FP100_MOUSE",
    "mass": {
        "chemical_mass": 94281.0,
        "monoisotopic_mass": 94281.0
    },
    "refseq": {
        "ac": "NP_082256",
        "name": "Fanconi anemia core complex-associated protein 100",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082256"
    },
    "gene_names": [
        {
            "name": "Faap100",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2ACJ2",
            "id": "A2ACJ2"
        },
        {
            "name": "2310003H01Rik",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082256",
            "id": "NP_082256"
        },
        {
            "name": "Faap100",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082256",
            "id": "NP_082256"
        }
    ],
    "protein_names": [
        {
            "name": "Fanconi anemia core complex-associated protein 100",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2ACJ2#names_and_taxonomy",
            "id": "A2ACJ2"
        },
        {
            "name": "Fanconi anemia core complex-associated protein 100",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082256",
            "id": "NP_082256"
        },
        {
            "name": "Fanconi anemia-associated protein of 100 kDa",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2ACJ2#names_and_taxonomy",
            "id": "A2ACJ2"
        },
        {
            "name": "fanconi anemia-associated protein of 100 kDa",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082256",
            "id": "NP_082256"
        }
    ],
    "function": [
        {
            "annotation": "Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2ACJ2",
                    "url": "https://www.uniprot.org/uniprot/A2ACJ2#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2ACJ2",
                    "url": "https://www.uniprot.org/uniprot/A2ACJ2"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Faap100",
            "url": "https://www.uniprot.org/uniprot/A2ACJ2",
            "locus": {
                "chromosome": "11",
                "start_pos": 120378764,
                "end_pos": 120369055,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000025384",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000025384"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000025384",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000025384",
            "database": "Bgee"
        },
        {
            "id": "71885",
            "url": "https://www.ncbi.nlm.nih.gov/gene/71885",
            "database": "GeneID"
        },
        {
            "id": "A2ACJ2",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A2ACJ2*",
            "database": "IntAct"
        },
        {
            "id": "IPR029251",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029251",
            "database": "InterPro"
        },
        {
            "id": "mmu:71885",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:71885",
            "database": "KEGG Pathway"
        },
        {
            "id": "1919135",
            "url": "http://www.informatics.jax.org/marker/MGI:1919135",
            "database": "MGI"
        },
        {
            "id": "QANHEML",
            "url": "https://omabrowser.org/oma/group/QANHEML/",
            "database": "OMA"
        },
        {
            "id": "129283at2759",
            "url": "http://www.orthodb.org/?query=129283at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PTHR14890",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14890",
            "database": "PANTHER"
        },
        {
            "id": "PF15146",
            "url": "http://pfam.xfam.org/family/PF15146",
            "database": "Pfam"
        },
        {
            "id": "PR_A2ACJ2",
            "url": "http://purl.obolibrary.org/obo/PR_A2ACJ2",
            "database": "PRO"
        },
        {
            "id": "R-MMU-6783310",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6783310",
            "database": "Reactome"
        },
        {
            "id": "NP_082256",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082256",
            "database": "RefSeq"
        },
        {
            "id": "A2ACJ2",
            "url": "https://www.uniprot.org/uniprot/A2ACJ2",
            "database": "UniProtKB"
        },
        {
            "id": "A2ACJ2-1",
            "url": "https://www.uniprot.org/uniprot/A2ACJ2-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MAGASSRVHYLSDFCCPLGGRAAGKPFVLRHEAEVFLSTGREFVYVYDQEGGLLTAVYQFPDQVWHLQLLAIRRALYVLCARTGIYCLSLDSLDRSGSQACEDKEEAAPPYPVIHVDPDACVLPDAALCAFTVLDDMLVTLAQGPTQWKMQLFERPCAGEEPLPRGQIGEVELSTCTPPGGVPEKPAAPRFLPVLCCVFPPDSRAPHGHPQGCGCFTLEEALFGLLFGVDATLLQSPVILCGLPDGQLCCVVLKALVTSGLAPGDPKVLVKILHHLEEPVIFIGALRAEPHEEEAAGELLPGQHEHSDCLVALGHQGRTLAIKASWSESGNLVPELREYCLPGPVLCAACDRDGHVYHSTPSDLCVVDLTRRDSPWNPEKPDGAIGGLPSVLCPASLNICSALALCVTARAPTGSTELLALSSKGRLITCSLDLNSEAPVPAKMAMANAGQKIKELLLDIGDVSERVSFLKKAVDQRNKAITSLNEAMNVSCALLSHPEGDRPIACTITTSWSRLELRDMLMATCTLENSSSFSLDQGWTLCIQVLTSSSALDLDGTGSAFTYTIPVDRLGPGSRREVTLPLGPSESGVLDLPVTMSCWLFYSLREVVGAALAPSDPLEAPYLEQFPLSLPKQEGVCLPLCKRTVDMLQCLRFAGAATHPAQAPCMPGPACEPVETFLKTCQAPGSEPTGAASLRAKYLPPSTASIRVSAGLLRAALEDSHSGFHLCSATLRWLLAENAAVDVVRAQTLSSIQGIAPDGTDVNLTVHEVAVTDLSPAGPIQAVEIQVESSSLANMCRAHHAIIRRIQTMVTEQAALGSSPPDLRMQYLQQIHANHQELLREVQALRDQLCTEDELSSCSTAQKLLHIYKQLRNPSLVLL",
        "length": 879,
        "header": "sp|A2ACJ2-1|FP100_MOUSE Isoform 1 of Fanconi anemia core complex-associated protein 100  OS=Mus musculus OX=10090 GN=Faap100 PE=2 SV=1 CANONICAL=A2ACJ2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A2ACJ2-1",
            "url": "https://www.uniprot.org/uniprot/A2ACJ2#A2ACJ2-1",
            "sequence": {
                "sequence": "MAGASSRVHYLSDFCCPLGGRAAGKPFVLRHEAEVFLSTGREFVYVYDQEGGLLTAVYQFPDQVWHLQLLAIRRALYVLCARTGIYCLSLDSLDRSGSQACEDKEEAAPPYPVIHVDPDACVLPDAALCAFTVLDDMLVTLAQGPTQWKMQLFERPCAGEEPLPRGQIGEVELSTCTPPGGVPEKPAAPRFLPVLCCVFPPDSRAPHGHPQGCGCFTLEEALFGLLFGVDATLLQSPVILCGLPDGQLCCVVLKALVTSGLAPGDPKVLVKILHHLEEPVIFIGALRAEPHEEEAAGELLPGQHEHSDCLVALGHQGRTLAIKASWSESGNLVPELREYCLPGPVLCAACDRDGHVYHSTPSDLCVVDLTRRDSPWNPEKPDGAIGGLPSVLCPASLNICSALALCVTARAPTGSTELLALSSKGRLITCSLDLNSEAPVPAKMAMANAGQKIKELLLDIGDVSERVSFLKKAVDQRNKAITSLNEAMNVSCALLSHPEGDRPIACTITTSWSRLELRDMLMATCTLENSSSFSLDQGWTLCIQVLTSSSALDLDGTGSAFTYTIPVDRLGPGSRREVTLPLGPSESGVLDLPVTMSCWLFYSLREVVGAALAPSDPLEAPYLEQFPLSLPKQEGVCLPLCKRTVDMLQCLRFAGAATHPAQAPCMPGPACEPVETFLKTCQAPGSEPTGAASLRAKYLPPSTASIRVSAGLLRAALEDSHSGFHLCSATLRWLLAENAAVDVVRAQTLSSIQGIAPDGTDVNLTVHEVAVTDLSPAGPIQAVEIQVESSSLANMCRAHHAIIRRIQTMVTEQAALGSSPPDLRMQYLQQIHANHQELLREVQALRDQLCTEDELSSCSTAQKLLHIYKQLRNPSLVLL",
                "length": 879,
                "header": "sp|A2ACJ2-1|FP100_MOUSE Isoform 1 of Fanconi anemia core complex-associated protein 100  OS=Mus musculus OX=10090 GN=Faap100 PE=2 SV=1 CANONICAL=A2ACJ2-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 120269532,
                "end_pos": 120261117,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000026448",
                        "url": "https://www.ensembl.org/id/ENSMUST00000026448"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000026448",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000026448"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:71885",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:71885",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-6783310",
            "name": "Fanconi Anemia Pathway",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6783310",
            "resource": "Reactome",
            "description": "Fanconi Anemia Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZX03-1",
            "protein_name": "FA core complex-associated protein 100",
            "gene_name": "Faap100",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MAGASSRVHYLSDFCCPLGGRAAGKPHVLRHDAEVFLSTGREFVYVYDQEGGLLTAVYQFPDQVWHLQLLATRRALYVLCARTGIYCLSLDSLDRSGSQACEDKEDETHPYPVIHVDPDACVLPDAALCAFTVLDDVLVTLAQGPTQWKMQLFECPHAGEEPRPGGQVGEVQLSTCTPPGGVPGEPTAPCFLPVLCCVFPPDSRAPHGHPQGCGCFMLEEALFGLLFGVDASLLQSPVVLCGLPDGQLCCVALKALVTSELAPGDPKVLVKILHHLEEPVIFIGALRAEPQEEEEEEAVRELLPVENVHSDCLVALGHQGRTLAIRASWSESGNLVPELREYYLPGPVLCAACGRDGHMYHSTPSDLCVVDLTRRDSTWNPEKPDGAIGSLPSTLCPASLNICSALALCVTARAPTGGTELLVLSSKGRLITCSLDLNPEAPVPTKMAVANAGQKIKELLLDIGDVSERVSFLKKAVDQRNKAITSLNEAMNVSCALLSSQEGDRPISCTITTSWSRLELRDMLMATCTLDNSSSFSLDQGWTLCIQVLTSSSALDLDGTGSAFTYTIPVDRLGPGSRREVTLPLGPSESGVLDLPVTMSCWLFYSLREVIGEALAPSDPLEVPYLEKLPLNLPKQEGVCLPLCKRTVDMLQCLRFPGVASHPAQAPSVPGPACDPVETFLKTCQGPGSEPTGAASLRAKYLPPSTASIRVSAGLLRAALEDGHSGFHLCSATLCWLLAENAAVDVLRAQALSSIQGIAPDGTDVNLIVHEVAVTDLSPAGPIQAVEIQVESSSLANMCRAHHAIIRRIKTMVTEQAAQGSSPPDLRMQYLQQIHANHQELLREVQTLRDQLCTEDEVSSCSTAQKLLQIYKQLRNPSLVLL",
                "length": 882
            },
            "evidence": [
                {
                    "id": "69394",
                    "url": "http://www.informatics.jax.org/homology/69394",
                    "database": "MGI"
                },
                {
                    "id": "A2ACJ2",
                    "url": "https://omabrowser.org/oma/group/A2ACJ2/",
                    "database": "OMA"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q0VG06-1",
            "protein_name": "Fanconi anemia core complex-associated protein 100",
            "gene_name": "FAAP100",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MAGAAPRVRYLAGFCCPLGGLAAGKPRVLCHEAEVFLSTGSELVYVYDQEGGLLTAAFRFPDQVWHLELLAPRRLLYALCARRGLYCLSLDHPGRSRSTSQDDRDSEDGDQPSPVIPVDPDACILPDAALCAFTLLDSVLVTLVQGPARWKMQLFEQPCPGEDPRPGGQIGEVELSSYTPPAGVPGKPAAPHFLPVLCSVSPSGSRVPHDLLGGSGGFTLEDALFGLLFGADATLLQSPVVLCGLPDGQLCCVILKALVTSRSAPGDPNALVKILHHLEEPVIFIGALKTEPQAAEAAENFLPDEDVHCDCLVAFGHHGRMLAIKASWDESGKLVPELREYCLPGPVLCAACGGGGRVYHSTPSDLCVVDLSRGSTPLGPEQPEEGPGGLPPMLCPASLNICSVVSLSASPRTHEGGTKLLALSAKGRLMTCSLDLDSEMPGPARMTTESAGQKIKELLSGIGNISERVSFLKKAVDQRNKALTSLNEAMNVSCALLSSGTGPRPISCTTSTTWSRLQTQDVLMATCVLENSSSFSLDQGWTLCIQVLTSSCALDLDSACSAITYTIPVDQLGPGARREVTLPLGPGENGGLDLPVTVSCTLFYSLREVVGGALAPSDSEDPFLDECPSDVLPEQEGVCLPLSRHTVDMLQCLRFPGLAPPHTRAPSPLGPTRDPVATFLETCREPGSQPAGPASLRAEYLPPSVASIKVSAELLRAALKDGHSGVPLCCATLQWLLAENAAVDVVRARALSSIQGVAPDGANVHLIVREVAMTDLCPAGPIQAVEIQVESSSLADICRAHHAVVGRMQTMVTEQATQGSSAPDLRVQYLRQIHANHETLLREVQTLRDRLCTEDEASSCATAQRLLQVYRQLRHPSLILL",
                "length": 881
            },
            "evidence": [
                {
                    "id": "69394",
                    "url": "http://www.informatics.jax.org/homology/69394",
                    "database": "MGI"
                },
                {
                    "id": "A2ACJ2",
                    "url": "https://omabrowser.org/oma/group/A2ACJ2/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "Fanconi anaemia nuclear complex",
                        "id": "GO:0043240",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043240",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ACJ2",
                                "url": "https://www.uniprot.org/uniprot/A2ACJ2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleoplasm",
                        "id": "GO:0005654",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ACJ2",
                                "url": "https://www.uniprot.org/uniprot/A2ACJ2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ACJ2",
                                "url": "https://www.uniprot.org/uniprot/A2ACJ2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "DNA binding",
                        "id": "GO:0003677",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ACJ2",
                                "url": "https://www.uniprot.org/uniprot/A2ACJ2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "interstrand cross-link repair",
                        "id": "GO:0036297",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2ACJ2",
                                "url": "https://www.uniprot.org/uniprot/A2ACJ2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 489,
            "end_pos": 491,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 529,
            "end_pos": 531,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 763,
            "end_pos": 765,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ]
}