{ "uniprot_canonical_ac": "A2A654-1", "uniprot_ac": "A2A654", "uniprot_id": "A2A654_MOUSE", "mass": { "chemical_mass": 333228.0, "monoisotopic_mass": 333228.0 }, "refseq": { "ac": "NP_789820", "name": "nucleosome-remodeling factor subunit BPTF isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820" }, "gene_names": [ { "name": "Bptf", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2A654", "id": "A2A654" }, { "name": "9430093H17Rik; Falz", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820", "id": "NP_789820" }, { "name": "Bptf", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820", "id": "NP_789820" } ], "protein_names": [ { "name": "Bromodomain PHD finger transcription factor", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2A654#names_and_taxonomy", "id": "A2A654" }, { "name": "fetal Alzheimer antigen", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820", "id": "NP_789820" }, { "name": "nucleosome-remodeling factor subunit BPTF isoform 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820", "id": "NP_789820" } ], "function": [ { "annotation": "An essential requirement of the chromatin remodeler BPTF and NURF for activation of 'stemness' gene-expression programs and proper function of adult HSCs.", "evidence": [ { "database": "RefSeq", "id": "NP_789820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820" }, { "database": "PubMed", "id": "29456179", "url": "https://glygen.org/publication/PubMed/29456179" } ] }, { "annotation": "Bptf determines oncogenic addiction in aggressive B-cell lymphomas.", "evidence": [ { "database": "RefSeq", "id": "NP_789820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820" }, { "database": "PubMed", "id": "32451433", "url": "https://glygen.org/publication/PubMed/32451433" } ] }, { "annotation": "Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma.", "evidence": [ { "database": "RefSeq", "id": "NP_789820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820" }, { "database": "PubMed", "id": "31065107", "url": "https://glygen.org/publication/PubMed/31065107" } ] } ], "disease": [ { "disease_id": "DOID:10652", "recommended_name": { "id": "DOID:10652", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." }, "synonyms": [ { "id": "DOID:10652", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10652", "name": "Alzheimer disease", "description": "" }, { "id": "DOID:10652", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10652", "name": "Alzheimers dementia", "description": "" } ], "evidence": [ { "id": "10652", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ] }, { "disease_id": "DOID:332", "recommended_name": { "id": "DOID:332", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing." }, "synonyms": [ { "id": "DOID:332", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:332", "name": "ALS", "description": "" }, { "id": "DOID:332", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:332", "name": "Lou Gehrig's disease", "description": "" }, { "id": "DOID:332", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:332", "name": "motor neuron disease, bulbar", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis type 1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1; ALS1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, autosomal dominant", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1, autosomal dominant amyotrophic lateral sclerosis 1, autosomal recessive, included", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1, autosomal recessive", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1, familial", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, familial", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "ALS1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "FALS", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, sporadic", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1, autosomal dominant", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, sporadic, included", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis type 1", "description": "" }, { "id": "MIM:105400", "resource": "MIM", "url": "https://www.omim.org/entry/105400", "name": "Amyotrophic lateral sclerosis 1", "description": "Amyotrophic lateral sclerosis 1" } ], "evidence": [ { "id": "332", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:332" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Bptf", "url": "https://www.uniprot.org/uniprot/A2A654", "locus": { "chromosome": "11", "start_pos": 107132127, "end_pos": 107033081, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000040481", "url": "https://www.ensembl.org/id/ENSMUSG00000040481" } ] } } ], "crossref": [ { "id": "ENSMUSG00000040481", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000040481", "database": "Bgee" }, { "id": "207165", "url": "https://www.ncbi.nlm.nih.gov/gene/207165", "database": "GeneID" }, { "id": "A2A654", "url": "https://www.ebi.ac.uk/intact/interactors/id:A2A654*", "database": "IntAct" }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro" }, { "id": "IPR001510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001510", "database": "InterPro" }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro" }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro" }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro" }, { "id": "IPR018359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018359", "database": "InterPro" }, { "id": "IPR018501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018501", "database": "InterPro" }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro" }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro" }, { "id": "IPR028941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028941", "database": "InterPro" }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro" }, { "id": "IPR038028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038028", "database": "InterPro" }, { "id": "2444008", "url": "http://www.informatics.jax.org/marker/MGI:2444008", "database": "MGI" }, { "id": "CDDRLQG", "url": "https://omabrowser.org/oma/group/CDDRLQG/", "database": "OMA" }, { "id": "343959at2759", "url": "http://www.orthodb.org/?query=343959at2759", "database": "OrthoDB" }, { "id": "PTHR45975", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45975", "database": "PANTHER" }, { "id": "PF00439", "url": "http://pfam.xfam.org/family/PF00439", "database": "Pfam" }, { "id": "PF00628", "url": "http://pfam.xfam.org/family/PF00628", "database": "Pfam" }, { "id": "PF02791", "url": "http://pfam.xfam.org/family/PF02791", "database": "Pfam" }, { "id": "PF15613", "url": "http://pfam.xfam.org/family/PF15613", "database": "Pfam" }, { "id": "NP_789820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820", "database": "RefSeq" }, { "id": "A0A140LHY5", "url": "https://www.uniprot.org/uniprot/A0A140LHY5", "database": "UniProtKB" }, { "id": "A0A140LHY5-1", "url": "https://www.uniprot.org/uniprot/A0A140LHY5-1", "database": "UniProtKB" }, { "id": "A2A652", "url": "https://www.uniprot.org/uniprot/A2A652", "database": "UniProtKB" }, { "id": "A2A652-1", "url": "https://www.uniprot.org/uniprot/A2A652-1", "database": "UniProtKB" }, { "id": "A2A653", "url": "https://www.uniprot.org/uniprot/A2A653", "database": "UniProtKB" }, { "id": "A2A653-1", "url": "https://www.uniprot.org/uniprot/A2A653-1", "database": "UniProtKB" }, { "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654", "database": "UniProtKB" }, { "id": "A2A654-1", "url": "https://www.uniprot.org/uniprot/A2A654-1", "database": "UniProtKB" }, { "id": "A2A655", "url": "https://www.uniprot.org/uniprot/A2A655", "database": "UniProtKB" }, { "id": "A2A655-1", "url": "https://www.uniprot.org/uniprot/A2A655-1", "database": "UniProtKB" }, { "id": "E9Q6A7", "url": "https://www.uniprot.org/uniprot/E9Q6A7", "database": "UniProtKB" }, { "id": "E9Q6A7-1", "url": "https://www.uniprot.org/uniprot/E9Q6A7-1", "database": "UniProtKB" } ], "sequence": { "sequence": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPPPPPPPPPPPPASGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGGRRKQPPPPPPASGSSASGPGRGGRGGGGGRTGGGGGHLARTTPARRAVNKVVYDDHESDDDDEEEDMVSEEDEEEEEDGDAEETQDSEDEEEDDMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVVRNFGNVLRLSPFCFEDFCAALVSQEQCTLMAEMHVALLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEVQKNKPYVRHEPIGYDRSRRKYWFLNRRLIIEEDTDNENEKKVWYYSTKVQLAELIDCLDKGYWEAELCRVLEDIREEMQQHMDVTEDLTNKARGSNKSFLAAANEEILDSLRIKRGEDIDCDQSPEDPEKDKHEGENNSSKDAEKSREEAEDPSADKDADSKGLEEEPGHGKPEEPTEVGDKGNSVPANLGDNTTNASPEETSPCDGRSPEGCLSETHDSSSMAEKKVASELPPDVPEDSNRTCDSSNTSATTASSQPNLETCSSSELTSSQSDSAKAADDPEIGERDSHTPVSVHEEIGDFRLEKSNGEVSESPGAGKGTSGSTRIITRLRNPESKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEVSRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLESNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVTGYGGWSWISKTHVYRFLPKLPGNTNVNYRKPLDGAKNNTDENKDESEKRKSPRSPKKMKTECDSEQGETRDADATAGAAAGAMELSKEPEKKDQDVKELLDSDNDKSFKEEPMEIDDTIKTESHVSSLESTEVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIRQFTLEEKQRLEKLKLESGVKGAGKPPMGALKSSSESPGSTKASEGHQGDSLRQEQSPSSSQASTVDLGLGGSQSDPLVLGISPPSLSTHKPDPKDQVLDDVSIQSPGPNCQRQNSVESDLDARISEPAGKGLELSQTKTEVTDSSSDDSKPTSADDVGILICKSRKLHSQDDSSTVVSSSKSTLPASVPKSPRDRDARAFSKAVDFDGRLGGDSEYSSTLENSSDNMCIRDSAEEDMVVQNSSEATSKRFIAPEQGGESVESTKCQVVSKSTENCEDKLQGKVTEANGKKLGQHPPKPEERAVNRCTDQVSLRHSVDRKNSEPRESEKKGQKANKFQINGKDSKAKGYLKGPGTKDGSDGKVVSSAVEPKVNNINKVIPGNTKSLAGKESAAKPFINGDIIMEELSEQNTSETNSYSLSSSDAKGNHQDGLHTLPSTKESASTQVITPRAPCPDRNSLSQVEDMETESPEVKRVIPSPVRTGEGSNLSKGFMDDNGLPSSKDENVNGESQRKTVITEVTTMTSTVATESKTVIKVAKGDKQTVVSSTENCARSTVTTTTTTVTKLSTPSPDTGVDTISVKEQSKTVVTTTVTDSLTTAGSTLVTSMTVSKEYSTRDRVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGSTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAAEQQTKKRLEQQKPAVIAASTTSPANNTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGMVQVQQKVLGIIPSTTGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGMTVIRTPLQQPALGKAIIRTPVVVQPGTPQQVVTQIIRGQPVSTAISAPSTASSAPVQKGLTPGAAAGPLQPSAPHSPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGMTVLPGPGQQLMQAAMPNGTVQRFLFTPLSTSATAASSSSNSSSTTTNATAAGSGEQKQSKILPQTQVQPATTLAPTQSSSVSPAEAQPQPAQPAAQPQPQPQPPAQPEVQTQPAVSSHVPSETQPSQAQTSKPLVATQCQPQSSVQGQSPVRVQSPPLTRIRPSTPSQVTPGQQPQVQTTASQPIPIPPPTSLQAPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVLSPSCPQPQPQVIAVPQLQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQVQQNSAAQTQSVVTVQAASVQEQLQRVQQLRDQQQKKKQQIETEREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILRKRALLDKELQIQVQEELKRDLKMKREREMAQAVQANAASVPTPSVPAPVPAPAPAAPPAPPRSPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDSKSKKKKMISTTSKEAKKDTRLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPRDTPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAP", "length": 3036, "header": "tr|A2A654-1|A2A654_MOUSE Isoform 1 of Bromodomain PHD finger transcription factor OS=Mus musculus OX=10090 GN=Bptf PE=1 SV=1 CANONICAL=A2A654-1" }, "isoforms": [ { "isoform_ac": "A0A140LHY5-1", "url": "https://www.uniprot.org/uniprot/A2A654#A0A140LHY5-1", "sequence": { "sequence": "EELKRDLKMKREREMAQAVQANAASVPTPSVPAPVPAPAPAAPPAPPRSPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDSKSKKKKMISTTSKEAKKDTRLYCICKTPYDESKFYIGCDLCTNWYHGECVGITEKEAKKMDVYICNDCKRAQEGSSEELYCICRTPYDESQFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPRDTPFYQCAEVLESFFVQKLKGFKASRL", "length": 329, "header": "tr|A0A140LHY5-1|A0A140LHY5_MOUSE Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Mus musculus OX=10090 GN=Bptf PE=1 SV=1 CANONICAL=A2A654-1" }, "locus": { "chromosome": "11", "start_pos": 106938169, "end_pos": 106927413, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000208369", "url": "https://www.ensembl.org/id/ENSMUST00000208369" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000146600", "url": "https://www.ensembl.org/id/ENSMUSP00000146600" } ] } }, { "isoform_ac": "A2A652-1", "url": "https://www.uniprot.org/uniprot/A2A654#A2A652-1", "sequence": { "sequence": "SKLSALLFKHKEQLKAEILRKRALLDKELQIQVQEELKRDLKMKREREMAQAVQANAASVPTPSVPAPVPAPAPAAPPAPPRSPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDSKSKKKKMISTTSKEAKKDTRLYCICKTPYDESKYVPVPQLCS", "length": 158, "header": "tr|A2A652-1|A2A652_MOUSE Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Mus musculus OX=10090 GN=Bptf PE=1 SV=1 CANONICAL=A2A654-1" }, "locus": { "chromosome": "11", "start_pos": 106943716, "end_pos": 106937798, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000133317", "url": "https://www.ensembl.org/id/ENSMUST00000133317" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000118875", "url": "https://www.ensembl.org/id/ENSMUSP00000118875" } ] } }, { "isoform_ac": "A2A653-1", "url": "https://www.uniprot.org/uniprot/A2A654#A2A653-1", "sequence": { "sequence": "VGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAAEQQTKKRLEQQKPAVIAASTTSPANNTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQSNSATSTAATSATTIASTGQTFQITGSPVTMAGKVITKLPLPANSKIVAVNVPATQGGMVQVQQKVLGIIPSTTGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGM", "length": 289, "header": "tr|A2A653-1|A2A654_MOUSE Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Mus musculus OX=10090 GN=Bptf PE=1 SV=1 CANONICAL=A2A654-1" }, "locus": { "chromosome": "11", "start_pos": 106958031, "end_pos": 106951374, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000149486", "url": "https://www.ensembl.org/id/ENSMUST00000149486" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000122575", "url": "https://www.ensembl.org/id/ENSMUSP00000122575" } ] } }, { "isoform_ac": "A2A654-1", "url": "https://www.uniprot.org/uniprot/A2A654#A2A654-1", "sequence": { "sequence": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPPPPPPPPPPPPASGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGGRRKQPPPPPPASGSSASGPGRGGRGGGGGRTGGGGGHLARTTPARRAVNKVVYDDHESDDDDEEEDMVSEEDEEEEEDGDAEETQDSEDEEEDDMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVVRNFGNVLRLSPFCFEDFCAALVSQEQCTLMAEMHVALLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEVQKNKPYVRHEPIGYDRSRRKYWFLNRRLIIEEDTDNENEKKVWYYSTKVQLAELIDCLDKGYWEAELCRVLEDIREEMQQHMDVTEDLTNKARGSNKSFLAAANEEILDSLRIKRGEDIDCDQSPEDPEKDKHEGENNSSKDAEKSREEAEDPSADKDADSKGLEEEPGHGKPEEPTEVGDKGNSVPANLGDNTTNASPEETSPCDGRSPEGCLSETHDSSSMAEKKVASELPPDVPEDSNRTCDSSNTSATTASSQPNLETCSSSELTSSQSDSAKAADDPEIGERDSHTPVSVHEEIGDFRLEKSNGEVSESPGAGKGTSGSTRIITRLRNPESKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEVSRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLESNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVTGYGGWSWISKTHVYRFLPKLPGNTNVNYRKPLDGAKNNTDENKDESEKRKSPRSPKKMKTECDSEQGETRDADATAGAAAGAMELSKEPEKKDQDVKELLDSDNDKSFKEEPMEIDDTIKTESHVSSLESTEVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIRQFTLEEKQRLEKLKLESGVKGAGKPPMGALKSSSESPGSTKASEGHQGDSLRQEQSPSSSQASTVDLGLGGSQSDPLVLGISPPSLSTHKPDPKDQVLDDVSIQSPGPNCQRQNSVESDLDARISEPAGKGLELSQTKTEVTDSSSDDSKPTSADDVGILICKSRKLHSQDDSSTVVSSSKSTLPASVPKSPRDRDARAFSKAVDFDGRLGGDSEYSSTLENSSDNMCIRDSAEEDMVVQNSSEATSKRFIAPEQGGESVESTKCQVVSKSTENCEDKLQGKVTEANGKKLGQHPPKPEERAVNRCTDQVSLRHSVDRKNSEPRESEKKGQKANKFQINGKDSKAKGYLKGPGTKDGSDGKVVSSAVEPKVNNINKVIPGNTKSLAGKESAAKPFINGDIIMEELSEQNTSETNSYSLSSSDAKGNHQDGLHTLPSTKESASTQVITPRAPCPDRNSLSQVEDMETESPEVKRVIPSPVRTGEGSNLSKGFMDDNGLPSSKDENVNGESQRKTVITEVTTMTSTVATESKTVIKVAKGDKQTVVSSTENCARSTVTTTTTTVTKLSTPSPDTGVDTISVKEQSKTVVTTTVTDSLTTAGSTLVTSMTVSKEYSTRDRVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGSTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAAEQQTKKRLEQQKPAVIAASTTSPANNTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGMVQVQQKVLGIIPSTTGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGMTVIRTPLQQPALGKAIIRTPVVVQPGTPQQVVTQIIRGQPVSTAISAPSTASSAPVQKGLTPGAAAGPLQPSAPHSPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGMTVLPGPGQQLMQAAMPNGTVQRFLFTPLSTSATAASSSSNSSSTTTNATAAGSGEQKQSKILPQTQVQPATTLAPTQSSSVSPAEAQPQPAQPAAQPQPQPQPPAQPEVQTQPAVSSHVPSETQPSQAQTSKPLVATQCQPQSSVQGQSPVRVQSPPLTRIRPSTPSQVTPGQQPQVQTTASQPIPIPPPTSLQAPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVLSPSCPQPQPQVIAVPQLQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQVQQNSAAQTQSVVTVQAASVQEQLQRVQQLRDQQQKKKQQIETEREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILRKRALLDKELQIQVQEELKRDLKMKREREMAQAVQANAASVPTPSVPAPVPAPAPAAPPAPPRSPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDSKSKKKKMISTTSKEAKKDTRLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPRDTPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAP", "length": 3036, "header": "tr|A2A654-1|A2A654_MOUSE Isoform 1 of Bromodomain PHD finger transcription factor OS=Mus musculus OX=10090 GN=Bptf PE=1 SV=1 CANONICAL=A2A654-1" }, "locus": { "chromosome": "11", "start_pos": 107022748, "end_pos": 106926632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000106763", "url": "https://www.ensembl.org/id/ENSMUST00000106763" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000102374", "url": "https://www.ensembl.org/id/ENSMUSP00000102374" } ] } }, { "isoform_ac": "A2A655-1", "url": "https://www.uniprot.org/uniprot/A2A654#A2A655-1", "sequence": { "sequence": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPPPPPPPPPPPPASGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGGRRKQPPPPPPASGSSASGPGRGGRGGGGGRTGGGGGHLARTTPARRAVNKVVYDDHESDDDDEEEDMVSEEDEEEEEDGDAEETQDSEDEEEDDMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVVRNFGNVLRLSPFCFEDFCAALVSQEQCTLMAEMHVALLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEVQKNKPYVRHEPIGYDRSRRKYWFLNRRLIIEEDTDNENEKKVWYYSTKVQLAELIDCLDKGYWEAELCRVLEDIREEMQQHMDVTEDLTNKARGSNKSFLAAANEEILDSLRIKRGEDIDCDQSPEDPEKDKHEGENNSSKDAEKSREEAEDPSADKDADSKGLEEEPGHGKPEEDSNRTCDSSNTSATTASSQPNLETCSSSELTSSQSDSAKAADDPEIGERDSHTPVSVHEEIGDFRLEKSNGEVSESPGAGKGTSGSTRIITRLRNPESKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEVSRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLESNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVTGYGGWSWISKTHVYRFLPKLPGNTNVNYRKPLDGAKNNTDENKDESEKRKSPRSPKKMKTECDSEQGETRDADATAGAAAGAMELSKEPEKKDQDVKELLDSDNDKSFKEEPMEIDDTIKTESHVSSLESTEVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIRQFTLEEKQRLEKLKLESGVKGAGKPPMGALKSSSESPGSTKASEGHQGDSLRQEQSPSSSQASTVDLGLGGSQSDPLVLGISPPSLSTHKPDPKDQVLDDVSIQSPGPNCQRQNSVESDLDARISEPAGKGLELSQTKTEVTDSSSDDSKPTSADDVGILICKSRKLHSQDDSSTVVSSSKSTLPASVPKSPRDRDARAFSKAVDFDGRLGGDSEYSSTLENSSDNMCIRDSAEEDMVVQNSSEATSKRFIAPEQGGESVESTKCQVVSKSTENCEDKLQGKVTEANGKKLGQHPPKPEERAVNRCTDQVSLRHSVDRKNSEPRESEKKGQKANKFQINGKDSKAKGYLKGPGTKDGSDGKVVSSAVEPKVNNINKVIPGNTKSLAGKESAAKPFINGDIIMEELSEQNTSETNSYSLSSSDAKGNHQDGLHTLPSTKESASTQVITPRAPCPDRNSLSQVEDMETESPEVKRVIPSPVRTGEGSNLSKGFMDDNGLPSSKDENVNGESQRKTVITEVTTMTSTVATESKTVIKVAKGDKQTVVSSTENCARSTVTTTTTTVTKLSTPSPDTGVDTISVKEQSKTVVTTTVTDSLTTAGSTLVTSMTVSKEYSTRDRVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGSTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAAEQQTKKRLEQQKPAVIAASTTSPANNTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGMVQVQQKVLGIIPSTTGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGMTVIRTPLQQPALGKAIIRTPVVVQPGTPQQVVTQIIRGQPVSTAISAPSTASSAPVQKGLTPGAAAGPLQPSAPHSPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGMTVLPGPGQQLMQAAMPNGTVQRFLFTPLSTSATAASSSSNSSSTTTNATAAGSGEQKQSKILPQTQVQPATTLAPTQSSSVSPAEAQPQPAQPAAQPQPQPQPPAQPEVQTQPAVSSHVPSETQPSQAQTSKPLVATQCQPQSSVQGQSPVRVQSPPLTRIRPSTPSQVTPGQQPQVQTTASQPIPIPPPTSLQAPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVLSPSCPQPQPQVIAVPQLQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQVQQNSAAQTQSVVTVQAASVQEQLQRVQQLRDQQQKKKQQIETEREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILRKRALLDKELQIQVQEELKRDLKMKREREMAQAVQANAASVPTPSVPAPVPAPAPAAPPAPPRSPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDSKSKKKKMISTTSKEAKKDTRLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPRDTPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAP", "length": 2973, "header": "tr|A2A655-1|A2A654_MOUSE Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Mus musculus OX=10090 GN=Bptf PE=1 SV=1 CANONICAL=A2A654-1" }, "locus": { "chromosome": "11", "start_pos": 107022748, "end_pos": 106926632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000106762", "url": "https://www.ensembl.org/id/ENSMUST00000106762" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000102373", "url": "https://www.ensembl.org/id/ENSMUSP00000102373" } ] } }, { "isoform_ac": "E9Q6A7-1", "url": "https://www.uniprot.org/uniprot/A2A654#E9Q6A7-1", "sequence": { "sequence": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPPPPPPPPPPPPASGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGGRRKQPPPPPPASGSSASGPGRGGRGGGGGRTGGGGGHLARTTPARRAVNKVVYDDHESDDDDEEEDMVSEEDEEEEEDGDAEETQDSEDEEEDDMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVVRNFGNVLRLSPFCFEDFCAALVSQEQCTLMAEMHVALLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEVQKNKPYVRHEPIGYDRSRRKYWFLNRRLIIEEDTDNENEKKVWYYSTKVQLAELIDCLDKGYWEAELCRVLEDIREEMQQHMDVTEDLTNKARGSNKSFLAAANEEILDSLRIKRGEDIDCDQSPEDPEKDKHEGENNSSKDAEKSREEAEDPSADKDADSKGLEEEPGHGKPEGDFRLEKSNGEVSESPGAGKGTSGSTRIITRLRNPESKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEVSRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLESNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVYRFLPKLPGNTNVNYRKPLDGAKNNTDENKDESEKRKSPRSPKKMKTECDSEQGETRDADATAGAAAGAMELSKEPEKKDQDVKELLDSDNDKSFKEEPMEIDDTIKTESHVSSLESTEVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIRQFTLEEKQRLEKLKLESGVKGAGKPPMGALKSSSESPGSTKASEGHQGDSLRQEQSPSSSQASTVDLGLGGSQSDPLVLGISPPSLSTHKPDPKDQVLDDVSIQSPGPNCQRQNSVESDLDARISEPAGKGLELSQTKTEVTDSSSDDSKPTSADDVGILICKSRKLHSQDDSSTVVSSSKSTLPASVPKSPRDRDARAFSKAVDFDGRLGGDSEYSSTLENSSDNMCIRDSAEEDMVVQNSSEATSKRFIAPEQGGESVESTKCQVVSKSTENCEDKLQGKVTEANGKKLGQHPPKPEERAVNRCTDQVSLRHSVDRKNSEPRESEKKGQKANKFQINGKDSKAKGYLKGPGTKDGSDGKVVSSAVEPKVNNINKVIPGNTKSLAGKESAAKPFINGDIIMEELSEQNTSETNSYSLSSSDAKGNHQDGLHTLPSTKESASTQVITPRAPCPDRNSLSQVEDMETESPEVKRVIPSPVRTGEGSNLSKGFMDDNGLPSSKDENVNGESQRKTVITEVTTMTSTVATESKTVIKVAKGDKQTVVSSTENCARSTVTTTTTTVTKLSTPSPDTGVDTISVKEQSKTVVTTTVTDSLTTAGSTLVTSMTVSKEYSTRDRVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGSTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAAEQQTKKRLEQQKPAVIAASTTSPANNTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGMVQVQQKVLGIIPSTTGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGMTVIRTPLQQPALGKAIIRTPVVVQPGTPQQVVTQIIRGQPVSTAISAPSTASSAPVQKGLTPGAAAGPLQPSAPHSPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGMTVLPGPGQQLMQAAMPNGTVQRFLFTPLSTSATAASSSSNSSSTTTNATAAGSGEQKQSKILPQTQVQPATTLAPTQSSSVSPAEAQPQPAQPAAQPQPQPQPPAQPEVQTQPAVSSHVPSETQPSQAQTSKPLVATQCQPQSSVQGQSPVRVQSPPLTRIRPSTPSQVTPGQQPQVQTTASQPIPIPPPTSLQAPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVLSPSCPQPQPQVIAVPQLQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQVQQNSAAQTQSVVTVQAASVQEQLQRVQQLRDQQQKKKQQIETEREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILRKRALLDKELQIQVQEELKRDLKMKREREMAQAVQANAASVPTPSVPAPVPAPAPAAPPAPPRSPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDSKSKKKKMISTTSKEAKKDTRLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPRDTPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAP", "length": 2921, "header": "tr|E9Q6A7-1|A2A654_MOUSE Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Mus musculus OX=10090 GN=Bptf PE=1 SV=1 CANONICAL=A2A654-1" }, "locus": { "chromosome": "11", "start_pos": 107022748, "end_pos": 106926632, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000057892", "url": "https://www.ensembl.org/id/ENSMUST00000057892" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000052303", "url": "https://www.ensembl.org/id/ENSMUSP00000052303" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.", "journal": "Mol. Cell. Proteomics", "date": "2014", "authors": "Beausoleil S.A., Wang Y., Zhou J., Comb M.J., Guo A., Lee K.A., Aguiar M., Bedford M.T., Gu H., Jia X., Kornhauser J., Mulhern D., Ren J., Silva J.C., Vemulapalli V., Yang V.", "evidence": [ { "database": "UniProtKB", "id": "A2A653", "url": "https://www.uniprot.org/uniprot/A2A653" }, { "database": "UniProtKB", "id": "A2A655", "url": "https://www.uniprot.org/uniprot/A2A655" }, { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" }, { "database": "UniProtKB", "id": "E9Q6A7", "url": "https://www.uniprot.org/uniprot/E9Q6A7" } ], "reference": [ { "type": "PubMed", "id": "24129315", "url": "https://glygen.org/publication/PubMed/24129315" } ] }, { "title": "The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells.", "journal": "Stem cell reports", "date": "2018", "authors": "Xu B, Cai L, Butler JM, Chen D, Lu X, Allison DF, Lu R, Rafii S, Parker JS, Zheng D, Wang GG", "evidence": [ { "database": "RefSeq", "id": "NP_789820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820" } ], "reference": [ { "type": "PubMed", "id": "29456179", "url": "https://glygen.org/publication/PubMed/29456179" } ] }, { "title": "Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma.", "journal": "Cell death and differentiation", "date": "2020", "authors": "Laurette P, Coassolo S, Davidson G, Michel I, Gambi G, Yao W, Sohier P, Li M, Mengus G, Larue L, Davidson I", "evidence": [ { "database": "RefSeq", "id": "NP_789820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820" } ], "reference": [ { "type": "PubMed", "id": "31065107", "url": "https://glygen.org/publication/PubMed/31065107" } ] }, { "title": "Bptf determines oncogenic addiction in aggressive B-cell lymphomas.", "journal": "Oncogene", "date": "2020", "authors": "Richart L, Felipe I, Delgado P, Andres MP, Prieto J, Pozo ND, Garcia JF, Piris MA, Ramiro A, Real FX", "evidence": [ { "database": "RefSeq", "id": "NP_789820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_789820" } ], "reference": [ { "type": "PubMed", "id": "32451433", "url": "https://glygen.org/publication/PubMed/32451433" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7N8-1", "protein_name": "Bromodomain PHD finger transcription factor", "gene_name": "Bptf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVPNEHIMNVIAIYEVVRNFGNVLRLSPFCFEDFCAALVSQEQCTLMAEMHVALLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVESKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEVQKNKPYVRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKVWYYSTKVQLAELIDCLDKDYWEAELCRVLEDIREEMQQHMDVTEDLTNKARGSNKSFLAAANEEILDSLRIKRGEDIDCDQNPEDTEKDKNEGENDSSKGAEKSREESEDQSPDKDADGKVLEEEPGQGKPEEPTEVGDKGNSVPANLGDNTRNASSEETPCEGRSPEGWLSETHDSSTAEKKVASELPPDVPEDSHKTCDSSNTSATTASSQPNLENCSSSSSSSELTSSQSDSAKAADDPDIGERDSHTPVSVQEEIGDFRLDKSNGEVSESPGTGKGTSGSTRIITRLRNPESKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEVSRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLESNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVRHQVWKQKGEEYRVTGYGGWSWISKTHVYRFLPKLPGNTNVNYRKPLEGVKNNMDENKDESDKRKSPRSPKKMKTECDSEKGEARDADSTAGATAGTMELSKLPEKEEHDVKELLDPDNDKPFKEEPMEIDDSVKTESHMNSEESAQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIRQFTLEEKQRLEKLKLESGVKGAGKPPTGAVKSSSEPPVSTKADEGHQGDLLRQEQRSTPSQAGTADLGLGASQSDPLVLGISPPSLSTGKPDPKGQVLDDVSIQSPGPACQGQNSVESDLDARISEATSKGLELSQTKTKVTDSLTDDSKPTSADEGSTLICKSKKPLPQDDCSTAVSSSSKSTLPAPVPKSPRDRDARAFPKAMDLDGRLGGDSEYNSTLENNSGTMYMRDSSEEDMVVQNSNDTTSKRFITPDQGMESTEPTKCQLVSKSTENCDNRLQGKVTEANGKKLGQHQKPEERAVNRCADQVSLRHSADRKNSEARESEKRGQKANKFQINGKDSKAKGYLKGPGMKDVSDGKVMSGAVEPKVNNINKVIPGNIKSLAGKESAVKPFVNGDIIMEEFSEQNTSETNSYSLSSSDAKGNHQDGLHTLPSTKDSASTQVIIPPAPCPDRNSLNQVEDMETEGPEVKKVTPSPITTGEDSNLGKDVMDENGLPSSKDENVNGESQRKTVITEVTTMTSTVATESKTVIKVAKGDKQTVVSSTENCARSTVTTTTTTVTKLSTPSPDSDVDTVSVKEQSKTVVTTTVTDSLSTAGSTLVTSMTVSREYSTRDRVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPCFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGSTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVVIESWVAEEELELWEIRAFAERVEKEKAQAVEQQTKKRLEQQKPAVIAASTTSPTNSTSSTVSPAQKVMVAPLSGSVTPGTKMVLATKVGSPATVTFQQNKNFHQTFATWVKQGQSNSATSTAATSATTIASTGQTLHITGSPVTMAGKVITKLPLPANSKIVAVNVPATQGGVVQVQQKVLGIIPSTAGPSQQTFTSFQPRTATVTIRPNTSASAGTTTTSQVITGPQIRPGMTVIRAPLQQPALGKAVIRTPVTMQPGAPQQVVTQIIRGQPVSTAISASSTASSAPVQKGLTPGAAAGTLQPSAPHSPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGMTVLPGPGQQLMQAAMPNGTVQRFLFTPLSTPVTAVSSSSSSSSTNATATGSGEQKQSKLSPQTQVQPATTLAPTQSSSVSPAEAQPQPAQPAAQPQPQPQPPAQPEVQTQPAASSHVPSETQPSQAQSSKPLVATQCQPQSSVQGQSPVRVQSPPLTRIRPSTPSQVTPGQQPQVQTTASQPIPIPPPTSLQAPSQGQPQSQPQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILKKRALLDKELQMQVQEELKRDLKMKREREMAQVVQANAAAGPTPSVPAPVPAPAPAPAAPPAPPSPPPSTHSLPPAGHPTAPLPVTSQKRKREEEKDSKSKKKKMISTTSKEAKKDTRLYCICKTPYDESKFYIGCDLCTNWYHGDCVGITEKEAKKMDVYICNDCKRAQEGSSEELYCICRTPYDESQFYIGCDRCQNWFHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERIQKRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRL", "length": 2768 }, "evidence": [ { "id": "A2A654", "url": "https://omabrowser.org/oma/group/A2A654/", "database": "OMA" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12830-1", "protein_name": "Nucleosome-remodeling factor subunit BPTF", "gene_name": "BPTF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNTTNATSEETSPSEGRSPVGCLSETPDSSNMAEKKVASELPQDVPEEPNKTCESSNTSATTTSIQPNLENSNSSSELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "length": 3046 }, "evidence": [ { "id": "114397", "url": "http://www.informatics.jax.org/homology/114397", "database": "MGI" }, { "id": "A2A654", "url": "https://omabrowser.org/oma/group/A2A654/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "18794365" }, { "name": "endoderm development", "id": "GO:0007492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007492", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "18974875" }, { "name": "embryonic placenta development", "id": "GO:0001892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001892", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "18794365" }, { "name": "nucleosome mobilization", "id": "GO:0042766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042766", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "21873635" }, { "name": "cellular response to nerve growth factor stimulus", "id": "GO:1990090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990090", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "NURF complex", "id": "GO:0016589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016589", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "21873635" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "methylated histone binding", "id": "GO:0035064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035064", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "21873635" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" }, { "name": "ATPase, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "A2A654", "url": "https://www.uniprot.org/uniprot/A2A654" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1068, "end_pos": 1070, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1168, "end_pos": 1170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1419, "end_pos": 1421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1438, "end_pos": 1440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1606, "end_pos": 1608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1683, "end_pos": 1685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2064, "end_pos": 2066, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2065, "end_pos": 2067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2165, "end_pos": 2167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2330, "end_pos": 2332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2353, "end_pos": 2355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2360, "end_pos": 2362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2644, "end_pos": 2646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2720, "end_pos": 2722, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 599, "end_pos": 601, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 904, "end_pos": 906, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ] }