{
    "uniprot_canonical_ac": "A2A5F7-1",
    "uniprot_ac": "A2A5F7",
    "uniprot_id": "A2A5F7_MOUSE",
    "mass": {
        "chemical_mass": 111481.0,
        "monoisotopic_mass": 111481.0
    },
    "refseq": {
        "ac": "NP_001074663",
        "name": "potassium voltage-gated channel subfamily H member 4",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074663"
    },
    "gene_names": [
        {
            "name": "Kcnh4",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2A5F7",
            "id": "A2A5F7"
        },
        {
            "name": "BEC2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074663",
            "id": "NP_001074663"
        },
        {
            "name": "Kcnh4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074663",
            "id": "NP_001074663"
        }
    ],
    "protein_names": [
        {
            "name": "potassium Voltage-gated channel, subfamily H (Eag-related), member 4",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A2A5F7#names_and_taxonomy",
            "id": "A2A5F7"
        },
        {
            "name": "potassium voltage-gated channel subfamily H member 4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074663",
            "id": "NP_001074663"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2A5F7",
                    "url": "https://www.uniprot.org/uniprot/A2A5F7"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Kcnh4",
            "url": "https://www.uniprot.org/uniprot/A2A5F7",
            "locus": {
                "chromosome": "11",
                "start_pos": 100759942,
                "end_pos": 100740376,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000035355",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000035355"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000035355",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000035355",
            "database": "Bgee"
        },
        {
            "id": "cd00038",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00038",
            "database": "CDD"
        },
        {
            "id": "cd00130",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00130",
            "database": "CDD"
        },
        {
            "id": "380728",
            "url": "https://www.ncbi.nlm.nih.gov/gene/380728",
            "database": "GeneID"
        },
        {
            "id": "IPR000014",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000014",
            "database": "InterPro"
        },
        {
            "id": "IPR000595",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000595",
            "database": "InterPro"
        },
        {
            "id": "IPR000700",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000700",
            "database": "InterPro"
        },
        {
            "id": "IPR001610",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001610",
            "database": "InterPro"
        },
        {
            "id": "IPR003938",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003938",
            "database": "InterPro"
        },
        {
            "id": "IPR003950",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003950",
            "database": "InterPro"
        },
        {
            "id": "IPR005821",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821",
            "database": "InterPro"
        },
        {
            "id": "IPR014710",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710",
            "database": "InterPro"
        },
        {
            "id": "IPR018490",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018490",
            "database": "InterPro"
        },
        {
            "id": "IPR035965",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035965",
            "database": "InterPro"
        },
        {
            "id": "mmu:380728",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:380728",
            "database": "KEGG Pathway"
        },
        {
            "id": "2156184",
            "url": "http://www.informatics.jax.org/marker/MGI:2156184",
            "database": "MGI"
        },
        {
            "id": "NVCFLGD",
            "url": "https://omabrowser.org/oma/group/NVCFLGD/",
            "database": "OMA"
        },
        {
            "id": "247304at2759",
            "url": "http://www.orthodb.org/?query=247304at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PF00520",
            "url": "http://pfam.xfam.org/family/PF00520",
            "database": "Pfam"
        },
        {
            "id": "PF13426",
            "url": "http://pfam.xfam.org/family/PF13426",
            "database": "Pfam"
        },
        {
            "id": "R-MMU-1296072",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1296072",
            "database": "Reactome"
        },
        {
            "id": "NP_001074663",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074663",
            "database": "RefSeq"
        },
        {
            "id": "A2A5F7",
            "url": "https://www.uniprot.org/uniprot/A2A5F7",
            "database": "UniProtKB"
        },
        {
            "id": "A2A5F7-1",
            "url": "https://www.uniprot.org/uniprot/A2A5F7-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFLLANAQGPRGFPIVYCSDGFCELTGYGRTEVMQKTCSCRFLYGPETSEPALQRLQKALEGHQEHRTEICFYRKDGSAFWCLLDMMPIKNEMGEVVLFLFSFKDISQSGGPGLGSPGIHGDNNHENSLGRRGTSSRLRSTKRQNRTVLHRLTGHFGRRGQSSVKANSNLFEPKPSVPEYKVASVGGSRCLLLHYSIPKAVWDGLILLATFYVAVTVPYNVCFAGDDDTPITSRHTLVSDIAVEMLFILDIILNFRTTYVSQSGQVISAPRSIGLHYLATWFFVDLIAALPFDLLYVFNITVTSLVHLLKTVRLLRLLRLLQKLERYSQCSAVVLTLLMSVFALLAHWMACVWYVIGRREMEANDPLLWDIGWLHELGKRLEEPYVNGSAGGPSRRSAYIAALYFTLSSLTSVGFGNVCANTDAEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSRRSLYHSRMKDLKDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDANELLRDFPDELRADIAMHLNREILQLPLFGAASRGCLRALSLHIKTSFCAPGEYLLRRGDALQAHYYVCSGSLEVLRDNMVLAILGKGDLIGADIPELGQEPGSGAGPSCVLKTSADVKALTYCGLQQLSSRGLAEVLRLYPEYAAAFRAGLPRDLTFNLRQGSENNGLGRFSRSPRLSQARSDTLGSSSDKTLPSITETEGGTEPGAGSKPRRPHLLPNLSPARPRGSLVSLLGEELPPFSALVSSPSLSPTPSPALAGRGQSPSPHGPPRGSAAWKPPQLLIPPLGTFGPPDLSPRIVDGIEDSSNTAEAPTFRFSKRPEPTRTRSQAPPSGPRLSRELATEAAEEVKEKVCRLNQEISRLNQEVSQLSRELRQVMGLLQARLGPPSHTAGPAWLPDLPCPHQRLPCISPHMSGPPPGLQNTTLAVVHCPASVGTVEIGATPSELRPSTIPPYPSEPDPLGPSPAPEAPPLTPSLLKHSFQSGSDTFH",
        "length": 1018,
        "header": "tr|A2A5F7-1|A2A5F7_MOUSE Isoform 1 of potassium Voltage-gated channel, subfamily H (Eag-related), member 4  OS=Mus musculus OX=10090 GN=Kcnh4 PE=2 SV=1 CANONICAL=A2A5F7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A2A5F7-1",
            "url": "https://www.uniprot.org/uniprot/A2A5F7#A2A5F7-1",
            "sequence": {
                "sequence": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFLLANAQGPRGFPIVYCSDGFCELTGYGRTEVMQKTCSCRFLYGPETSEPALQRLQKALEGHQEHRTEICFYRKDGSAFWCLLDMMPIKNEMGEVVLFLFSFKDISQSGGPGLGSPGIHGDNNHENSLGRRGTSSRLRSTKRQNRTVLHRLTGHFGRRGQSSVKANSNLFEPKPSVPEYKVASVGGSRCLLLHYSIPKAVWDGLILLATFYVAVTVPYNVCFAGDDDTPITSRHTLVSDIAVEMLFILDIILNFRTTYVSQSGQVISAPRSIGLHYLATWFFVDLIAALPFDLLYVFNITVTSLVHLLKTVRLLRLLRLLQKLERYSQCSAVVLTLLMSVFALLAHWMACVWYVIGRREMEANDPLLWDIGWLHELGKRLEEPYVNGSAGGPSRRSAYIAALYFTLSSLTSVGFGNVCANTDAEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSRRSLYHSRMKDLKDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDANELLRDFPDELRADIAMHLNREILQLPLFGAASRGCLRALSLHIKTSFCAPGEYLLRRGDALQAHYYVCSGSLEVLRDNMVLAILGKGDLIGADIPELGQEPGSGAGPSCVLKTSADVKALTYCGLQQLSSRGLAEVLRLYPEYAAAFRAGLPRDLTFNLRQGSENNGLGRFSRSPRLSQARSDTLGSSSDKTLPSITETEGGTEPGAGSKPRRPHLLPNLSPARPRGSLVSLLGEELPPFSALVSSPSLSPTPSPALAGRGQSPSPHGPPRGSAAWKPPQLLIPPLGTFGPPDLSPRIVDGIEDSSNTAEAPTFRFSKRPEPTRTRSQAPPSGPRLSRELATEAAEEVKEKVCRLNQEISRLNQEVSQLSRELRQVMGLLQARLGPPSHTAGPAWLPDLPCPHQRLPCISPHMSGPPPGLQNTTLAVVHCPASVGTVEIGATPSELRPSTIPPYPSEPDPLGPSPAPEAPPLTPSLLKHSFQSGSDTFH",
                "length": 1018,
                "header": "tr|A2A5F7-1|A2A5F7_MOUSE Isoform 1 of potassium Voltage-gated channel, subfamily H (Eag-related), member 4  OS=Mus musculus OX=10090 GN=Kcnh4 PE=2 SV=1 CANONICAL=A2A5F7-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 100650431,
                "end_pos": 100632432,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000107363",
                        "url": "https://www.ensembl.org/id/ENSMUST00000107363"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000102986",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000102986"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "mmu:380728",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:380728",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-1296072",
            "name": "Voltage gated Potassium channels",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1296072",
            "resource": "Reactome",
            "description": "Voltage gated Potassium channels"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9R1T9-1",
            "protein_name": "Potassium voltage-gated channel subfamily H member 4",
            "gene_name": "Kcnh4",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFLLANAQGPRGFPIVYCSDGFCELTGYGRTEVMQKTCSCRFLYGPETSEPALQRLQKALEGHQEHRAEICFYRKDGSAFWCLLDMMPIKNELGEVVLFLFSFKDISQSGGPGLGSPGIHGDNNNHENSLGRRGASSRLRSTRRQNRTVLHRLTGHFGRRDQGSVKANSNVFEPKPSVPEYKVASVGGSRCLLLHYSIPKAVWDGLILLATFYVAVTVPYNVCFAGDDDTPITSRHTLVSDIAVEMLFILDIILNFRTTYVSQSGQVVSAPRSIGLHYLATWFFVDLIAALPFDLLYVFNITVTSLVHLLKTVRLLRLLRLLQKLERYSQCSAVVLTLLMSVFALLAHWMACVWYVIGRREMEANDPLLWDIGWLHELGKRLEEPYVNGSAGGPSRRSAYIAALYFTLSSLTSVGFGNVCANTDAEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSRRSLYHSRMKDLKDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDANELLRDFPDELRADIAMHLNREILQLPLFGAASRGCLRALSLHIKTSFCAPGEFLLRRGDALQAHYYVCSGSLEVLRDNTVLAILGKGDLIGADIPELGQEPGAGAGCVLKTSADVKALTYCGLQQLSSRGLAEVLRLYPEYVAAFRAGLPRDLTFNLRQGSENNGLGRFSRSPRLSQARSDTLGSSSDKTLPSITETEGGMEPGAGSKPRRPLLLPNLSPARPRGSLVSLLGEELPPFSALVSSPSLSPTPSPALAGRGSSPSLHGPPRGSAAWKPPQLLTPPLGTFGPPDLSPRIVDGIEDSSNTAEAPTFRFSKRPEPTRTRSQAPLSGPRLSRELATEAAEEVKEKVCRLNQEISRLNQEVSQLSRELRQVMGLLQARLGPPSHPPDSTWLPDLPCPHQRPPCISPHMSGPPPGLQNTTLAVVHCPASVGTVEIGATPSELRSSMVPPFPSEPDPLGPSPVPEASPLTPSLLKHSFQSGSDTFH",
                "length": 1017
            },
            "evidence": [
                {
                    "id": "8180",
                    "url": "http://www.informatics.jax.org/homology/8180",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q9UQ05-1",
            "protein_name": "Potassium voltage-gated channel subfamily H member 4",
            "gene_name": "KCNH4",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFLLANAQGTRGFPIVYCSDGFCELTGYGRTEVMQKTCSCRFLYGPETSEPALQRLHKALEGHQEHRAEICFYRKDGSAFWCLLDMMPIKNEMGEVVLFLFSFKDITQSGSPGLGPQGGRGDSNHENSLGRRGATWKFRSARRRSRTVLHRLTGHFGRRGQGGMKANNNVFEPKPSVPEYKVASVGGSRCLLLHYSVSKAIWDGLILLATFYVAVTVPYNVCFSGDDDTPITSRHTLVSDIAVEMLFILDIILNFRTTYVSQSGQVISAPRSIGLHYLATWFFIDLIAALPFDLLYIFNITVTSLVHLLKTVRLLRLLRLLQKLERYSQCSAVVLTLLMSVFALLAHWMACIWYVIGRREMEANDPLLWDIGWLHELGKRLEVPYVNGSVGGPSRRSAYIAALYFTLSSLTSVGFGNVCANTDAEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSRRSLYHSRMKDLKDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDANELLRDFPDELRADIAMHLNREILQLPLFGAASRGCLRALSLHIKTSFCAPGEYLLRRGDALQAHYYVCSGSLEVLRDNMVLAILGKGDLIGADIPEPGQEPGLGADPNFVLKTSADVKALTYCGLQQLSSRGLAEVLRLYPEYGAAFRAGLPRDLTFNLRQGSDTSGLSRFSRSPRLSQPRSESLGSSSDKTLPSITEAESGAEPGGGPRPRRPLLLPNLSPARPRGSLVSLLGEELPPFSALVSSPSLSPSLSPALAGQGHSASPHGPPRCSAAWKPPQLLIPPLGTFGPPDLSPRIVDGIEDSGSTAEAPSFRFSRRPELPRPRSQAPPTGTRPSPELASEAEEVKEKVCRLNQEISRLNQEVSQLSRELRHIMGLLQARLGPPGHPAGSAWTPDPPCPQLRPPCLSPCASRPPPSLQDTTLAEVHCPASVGTMETGTALLDLRPSILPPYPSEPDPLGPSPVPEASPPTPSLLRHSFQSRSDTFH",
                "length": 1017
            },
            "evidence": [
                {
                    "id": "8180",
                    "url": "http://www.informatics.jax.org/homology/8180",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "integral component of plasma membrane",
                        "id": "GO:0005887",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005887",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2A5F7",
                                "url": "https://www.uniprot.org/uniprot/A2A5F7"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "regulation of membrane potential",
                        "id": "GO:0042391",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2A5F7",
                                "url": "https://www.uniprot.org/uniprot/A2A5F7"
                            }
                        ],
                        "pmid": "21873635"
                    },
                    {
                        "name": "regulation of ion transmembrane transport",
                        "id": "GO:0034765",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034765",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2A5F7",
                                "url": "https://www.uniprot.org/uniprot/A2A5F7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "potassium ion transmembrane transport",
                        "id": "GO:0071805",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2A5F7",
                                "url": "https://www.uniprot.org/uniprot/A2A5F7"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "voltage-gated potassium channel activity",
                        "id": "GO:0005249",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2A5F7",
                                "url": "https://www.uniprot.org/uniprot/A2A5F7"
                            }
                        ],
                        "pmid": "21873635"
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 172,
            "end_pos": 174,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 326,
            "end_pos": 328,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 414,
            "end_pos": 416,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 473,
            "end_pos": 475,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 748,
            "end_pos": 750,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 951,
            "end_pos": 953,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}