{
    "uniprot_canonical_ac": "A1L112-1",
    "uniprot_ac": "A1L112",
    "uniprot_id": "WDR55_RAT",
    "mass": {
        "chemical_mass": 42142.0,
        "monoisotopic_mass": 42142.0
    },
    "refseq": {
        "ac": "NP_001017932",
        "name": "WD repeat-containing protein 55",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017932"
    },
    "gene_names": [
        {
            "name": "Ik",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A1L112",
            "id": "A1L112"
        },
        {
            "name": "Wdr55",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A1L112",
            "id": "A1L112"
        },
        {
            "name": "Ik",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A1L112",
            "id": "A1L112"
        },
        {
            "name": "LRRG00133; RGD1305640",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017932",
            "id": "NP_001017932"
        },
        {
            "name": "Wdr55",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017932",
            "id": "NP_001017932"
        }
    ],
    "protein_names": [
        {
            "name": "WD repeat-containing protein 55",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A1L112#names_and_taxonomy",
            "id": "A1L112"
        },
        {
            "name": "WD repeat-containing protein 55",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017932",
            "id": "NP_001017932"
        }
    ],
    "function": [
        {
            "annotation": "Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A1L112",
                    "url": "https://www.uniprot.org/uniprot/A1L112#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A1L112",
                    "url": "https://www.uniprot.org/uniprot/A1L112"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Wdr55",
            "url": "https://www.uniprot.org/uniprot/A1L112",
            "locus": {
                "chromosome": "18",
                "start_pos": 29587901,
                "end_pos": 29608338,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000017251",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000017251"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000017251",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000017251",
            "database": "Bgee"
        },
        {
            "id": "307494",
            "url": "https://www.ncbi.nlm.nih.gov/gene/307494",
            "database": "GeneID"
        },
        {
            "id": "IPR001680",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680",
            "database": "InterPro"
        },
        {
            "id": "IPR012492",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012492",
            "database": "InterPro"
        },
        {
            "id": "IPR012916",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012916",
            "database": "InterPro"
        },
        {
            "id": "IPR015943",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943",
            "database": "InterPro"
        },
        {
            "id": "IPR017422",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017422",
            "database": "InterPro"
        },
        {
            "id": "IPR019775",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775",
            "database": "InterPro"
        },
        {
            "id": "IPR024977",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR024977",
            "database": "InterPro"
        },
        {
            "id": "IPR036322",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322",
            "database": "InterPro"
        },
        {
            "id": "IPR039896",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039896",
            "database": "InterPro"
        },
        {
            "id": "rno:307494",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:307494",
            "database": "KEGG Pathway"
        },
        {
            "id": "PEYKSAK",
            "url": "https://omabrowser.org/oma/group/PEYKSAK/",
            "database": "OMA"
        },
        {
            "id": "1173229at2759",
            "url": "http://www.orthodb.org/?query=1173229at2759",
            "database": "OrthoDB"
        },
        {
            "id": "PTHR12765",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12765",
            "database": "PANTHER"
        },
        {
            "id": "PF00400",
            "url": "http://pfam.xfam.org/family/PF00400",
            "database": "Pfam"
        },
        {
            "id": "PF07807",
            "url": "http://pfam.xfam.org/family/PF07807",
            "database": "Pfam"
        },
        {
            "id": "PF07808",
            "url": "http://pfam.xfam.org/family/PF07808",
            "database": "Pfam"
        },
        {
            "id": "PF12894",
            "url": "http://pfam.xfam.org/family/PF12894",
            "database": "Pfam"
        },
        {
            "id": "PR_A1L112",
            "url": "http://purl.obolibrary.org/obo/PR_A1L112",
            "database": "PRO"
        },
        {
            "id": "NP_001017932",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017932",
            "database": "RefSeq"
        },
        {
            "id": "1305640",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1305640",
            "database": "RGD"
        },
        {
            "id": "1359352",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1359352",
            "database": "RGD"
        },
        {
            "id": "A0A0G2K5G9",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K5G9",
            "database": "UniProtKB"
        },
        {
            "id": "A0A0G2K5G9-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K5G9-1",
            "database": "UniProtKB"
        },
        {
            "id": "A1L112",
            "url": "https://www.uniprot.org/uniprot/A1L112",
            "database": "UniProtKB"
        },
        {
            "id": "A1L112-1",
            "url": "https://www.uniprot.org/uniprot/A1L112-1",
            "database": "UniProtKB"
        },
        {
            "id": "Q6QI75",
            "url": "https://www.uniprot.org/uniprot/Q6QI75",
            "database": "UniProtKB"
        },
        {
            "id": "Q6QI75-1",
            "url": "https://www.uniprot.org/uniprot/Q6QI75-1",
            "database": "UniProtKB"
        }
    ],
    "sequence": {
        "sequence": "MDPTCQESPAEDSNNEEDLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGETKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHVLDVEQGQLERRISKAHSAPINSLLLVDENVLVTGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVALMKYGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEELALSHCGHFLASSGHDQRLKFWDMTQLRTVVVDDYRRRKKKGGPLRALSSKAWSTDDFFAGLREDEEEAKAPEEVSGESDDDSD",
        "length": 384,
        "header": "sp|A1L112-1|WDR55_RAT Isoform 1 of WD repeat-containing protein 55  OS=Rattus norvegicus OX=10116 GN=Wdr55 PE=2 SV=1 CANONICAL=A1L112-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K5G9-1",
            "url": "https://www.uniprot.org/uniprot/A1L112#A0A0G2K5G9-1",
            "sequence": {
                "sequence": "MPERDSEPFSNPLAPDGHDVDDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKSYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRERDRERDRERERERDREREREEEKKRHSYFEKPKVDDEPMDVDKGPGSAKELIKSINEKFAGSAGWEGTESHMLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIEKRKKMEADGVEVKRPKY",
                "length": 559,
                "header": "tr|A0A0G2K5G9-1|WDR55_RAT Computationally mapped isoform of WD repeat-containing protein 55  OS=Rattus norvegicus OX=10116 GN=Wdr55 PE=2 SV=1 CANONICAL=A1L112-1"
            },
            "locus": {
                "chromosome": "18",
                "start_pos": 29602503,
                "end_pos": 29588023,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000085470",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000085470"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000073422",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000073422"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A1L112-1",
            "url": "https://www.uniprot.org/uniprot/A1L112#A1L112-1",
            "sequence": {
                "sequence": "MDPTCQESPAEDSNNEEDLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGETKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHVLDVEQGQLERRISKAHSAPINSLLLVDENVLVTGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVALMKYGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEELALSHCGHFLASSGHDQRLKFWDMTQLRTVVVDDYRRRKKKGGPLRALSSKAWSTDDFFAGLREDEEEAKAPEEVSGESDDDSD",
                "length": 384,
                "header": "sp|A1L112-1|WDR55_RAT Isoform 1 of WD repeat-containing protein 55  OS=Rattus norvegicus OX=10116 GN=Wdr55 PE=2 SV=1 CANONICAL=A1L112-1"
            },
            "locus": {}
        },
        {
            "isoform_ac": "Q6QI75-1",
            "url": "https://www.uniprot.org/uniprot/A1L112#Q6QI75-1",
            "sequence": {
                "sequence": "MPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKSYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRERDRERDRERERERDREREREEEKKRHSYFEKPKVDDEHMLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIEKRKKMEADGALPIRPTRGSNYLGHAPILVVCSPARVDPMDPTCQESPAEDSNNEEDLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGETKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHVLDVEQGQLERRISKAHSAPINSLLLVDENVLVTGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVALMKYGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEELALSHCGHFLASSGHDQRLKFWDMTQLRTVVVDDYRRRKKKGGPLRALSSKAWSTDDFFAGLREDEEEAKAPEEVSGESDDDSD",
                "length": 872,
                "header": "tr|Q6QI75-1|WDR55_RAT Computationally mapped isoform of WD repeat-containing protein 55  OS=Rattus norvegicus OX=10116 GN=Wdr55 PE=2 SV=1 CANONICAL=A1L112-1"
            },
            "locus": {
                "chromosome": "18",
                "start_pos": 29608335,
                "end_pos": 29591611,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000043271",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000043271"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000044213",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000044213"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 354,
            "end_pos": 354,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A1L112",
                    "url": "https://www.uniprot.org/uniprot/A1L112"
                }
            ]
        },
        {
            "start_pos": 383,
            "end_pos": 383,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A1L112",
                    "url": "https://www.uniprot.org/uniprot/A1L112"
                }
            ]
        }
    ],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:307494",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:307494",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9CX97-1",
            "protein_name": "WD repeat-containing protein 55",
            "gene_name": "Wdr55",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MDPTCEESPAEDSNNEEEDLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGETKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHILDVEQGQLERRISKAHSAPINSVLLVDENALVTGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVALMKYGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCIVPVTENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEALALSHCGHFLASSGHDQRLKFWDMTQLRTVVVDDYRRRKKKGGPLRALSSKAWSTDDFFAGLREDEEDAKAPEEVVRESDDDDDDSD",
                "length": 388
            },
            "evidence": [
                {
                    "id": "9789",
                    "url": "http://www.informatics.jax.org/homology/9789",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q9H6Y2-1",
            "protein_name": "WD repeat-containing protein 55",
            "gene_name": "WDR55",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MDRTCEERPAEDGSDEEDPDSMEAPTRIRDTPEDIVLEAPASGLAFHPARDLLAAGDVDGDVFVFSYSCQEGETKELWSSGHHLKACRAVAFSEDGQKLITVSKDKAIHVLDVEQGQLERRVSKAHGAPINSLLLVDENVLATGDDTGGICLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGIFNIKRRRFELLSEPQSGDLTSVTLMKWGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTESLLCTGSTDGVIRAVNILPNRVVGSVGQHTGEPVEELALSHCGRFLASSGHDQRLKFWDMAQLRAVVVDDYRRRKKKGGPLRALSSKTWSTDDFFAGLREEGEDSMAQEEKEETGDDSD",
                "length": 383
            },
            "evidence": [
                {
                    "id": "9789",
                    "url": "http://www.informatics.jax.org/homology/9789",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A1L112",
                                "url": "https://www.uniprot.org/uniprot/A1L112"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleolus",
                        "id": "GO:0005730",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A1L112",
                                "url": "https://www.uniprot.org/uniprot/A1L112"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A1L112",
                                "url": "https://www.uniprot.org/uniprot/A1L112"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "rRNA processing",
                        "id": "GO:0006364",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A1L112",
                                "url": "https://www.uniprot.org/uniprot/A1L112"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ]
}