{ "uniprot_canonical_ac": "A0A0G2JUE9-1", "uniprot_ac": "A0A0G2JUE9", "uniprot_id": "A0A0G2JUE9_RAT", "mass": { "chemical_mass": 34531.0, "monoisotopic_mass": 34531.0 }, "refseq": { "ac": "NP_001000756", "name": "olfactory receptor Olr358", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000756" }, "gene_names": [ { "name": "Olr358", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9", "id": "A0A0G2JUE9" }, { "name": "Olr358", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000756", "id": "NP_001000756" } ], "protein_names": [ { "name": "Olfactory receptor", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9#names_and_taxonomy", "id": "A0A0G2JUE9" }, { "name": "olfactory receptor Olr358", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000756", "id": "NP_001000756" }, { "name": "olfactory receptor gene Olr358", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000756", "id": "NP_001000756" } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001000756", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000756" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUE9", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9" } ], "common_name": "Rat" } ], "gene": [ { "name": "Olr358", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9", "locus": { "chromosome": "1", "start_pos": 230079916, "end_pos": 230078984, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000059089", "url": "https://www.ensembl.org/id/ENSRNOG00000059089" } ] } } ], "crossref": [ { "id": "405027", "url": "https://www.ncbi.nlm.nih.gov/gene/405027", "database": "GeneID" }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro" }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro" }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro" }, { "id": "rno:405027", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:405027", "database": "KEGG Pathway" }, { "id": "QMYIFVA", "url": "https://omabrowser.org/oma/group/QMYIFVA/", "database": "OMA" }, { "id": "979582at2759", "url": "http://www.orthodb.org/?query=979582at2759", "database": "OrthoDB" }, { "id": "PF13853", "url": "http://pfam.xfam.org/family/PF13853", "database": "Pfam" }, { "id": "NP_001000756", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000756", "database": "RefSeq" }, { "id": "1333912", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1333912", "database": "RGD" }, { "id": "A0A0G2JUE9", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9", "database": "UniProtKB" }, { "id": "A0A0G2JUE9-1", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9-1", "database": "UniProtKB" } ], "sequence": { "sequence": "MENNTKVTEFLLLGLTIDPGLQLPLFMLFLLIYTITLVGNVGMILMIFLDSCLHTPMYFFLGNLSLVDFCYSSAVTPTVMTGLLIGNNVISYNDCAAQMFFFVAFATVENYLLASMAYDRYAAVCKPLHYATTMTTSVCACLSIGSYACGFLNASINTWNTFRLSFCRSNMVHHFFCEIPAVMVLSCSDRRVSELVLVYLGSFSILFALLVISISYILIFITIFKMHSSAGYGKAVSTCASHFTAVSIFYGTVIFIYLLPSSSHAMDTDSIASVFYTMIIPMLNPLVYSLRNKEVKSAFTKVFQWQSSLQ", "length": 310, "header": "tr|A0A0G2JUE9-1|A0A0G2JUE9_RAT Isoform 1 of Olfactory receptor OS=Rattus norvegicus OX=10116 GN=Olr358 PE=3 SV=1 CANONICAL=A0A0G2JUE9-1" }, "isoforms": [ { "isoform_ac": "A0A0G2JUE9-1", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9#A0A0G2JUE9-1", "sequence": { "sequence": "MENNTKVTEFLLLGLTIDPGLQLPLFMLFLLIYTITLVGNVGMILMIFLDSCLHTPMYFFLGNLSLVDFCYSSAVTPTVMTGLLIGNNVISYNDCAAQMFFFVAFATVENYLLASMAYDRYAAVCKPLHYATTMTTSVCACLSIGSYACGFLNASINTWNTFRLSFCRSNMVHHFFCEIPAVMVLSCSDRRVSELVLVYLGSFSILFALLVISISYILIFITIFKMHSSAGYGKAVSTCASHFTAVSIFYGTVIFIYLLPSSSHAMDTDSIASVFYTMIIPMLNPLVYSLRNKEVKSAFTKVFQWQSSLQ", "length": 310, "header": "tr|A0A0G2JUE9-1|A0A0G2JUE9_RAT Isoform 1 of Olfactory receptor OS=Rattus norvegicus OX=10116 GN=Olr358 PE=3 SV=1 CANONICAL=A0A0G2JUE9-1" }, "locus": { "chromosome": "1", "start_pos": 230079916, "end_pos": 230078987, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000091024", "url": "https://www.ensembl.org/id/ENSRNOT00000091024" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000069071", "url": "https://www.ensembl.org/id/ENSRNOP00000069071" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "rno:405027", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:405027", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K3F7-1", "protein_name": "Olfactory receptor", "gene_name": "Olr349", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MENNTKVTEFLLLGLTNDPGLQLPLFMIFLLIYTITMIGNLGLILLIFLDFRLHTPMYFFLGNLSLVDFCYSSAVTPKVMTGLLIGNKVISYNDCAAQMFFFVAFASVENYLLASMAYDRYAAVCKPLHYATTMTTSMCACLSIGSYVCGFLNASIHTGDTFSLSFCRSNIVHHFFCEIPAVMVLSCSDRHVSELVLFYVVSFNIFLALLVISISYILIFITIFKMHSSAGYGKAVSTCASHFTAVSIFYGTVIFMYLLPSSSHSMDTDPIASVFYTMIIPMLNPLVYSLRNKEVKSAFTKIFQVAK", "length": 307 }, "evidence": [ { "id": "133676", "url": "http://www.informatics.jax.org/homology/133676", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VFK3-1", "protein_name": "Olfactory receptor", "gene_name": "Olfr1457", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLMENNTKVTEFLLLGLTNDPELQLPLFLIFLLIYTITLVGNLGLILLIVLDSCLHTPMYIFLGNLSLVDFCYSSAVTPSVMTELLIGKKVISYNDCAAQTFFFVAFCTVENYLLASMAYDRYAAVCKPLHYASTMTTRVCIYLSIGSYVCGFLNASINTGNTFSLFFCRYNMIHHFFCDIPAVMVLSCSDRYFSELLLVYVVSFSIFFALLVICISYIFIFITIAKMHSSAGYGKAAPTCASHFTAVSIFYGTVIFMYLLPSSSHSMDTDQIASVFYTMIIPMLNPLVYSLRNKEVKSAFTKIFQVAKQSVMLYF", "length": 317 }, "evidence": [ { "id": "133676", "url": "http://www.informatics.jax.org/homology/133676", "database": "MGI" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUE9", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUE9", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9" } ], "pmid": "21873635" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUE9", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9" } ], "pmid": "21873635" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUE9", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9" } ], "pmid": "" }, { "name": "integral component of membrane", "id": "GO:0016021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUE9", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUE9", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9" } ], "pmid": "21873635" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JUE9", "url": "https://www.uniprot.org/uniprot/A0A0G2JUE9" } ], "pmid": "21873635" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" } ] }