{
    "disease_id": "DOID:2340",
    "recommended_name": {
        "id": "DOID:2340",
        "resource": "Disease Ontology",
        "url": "http://disease-ontology.org/term/DOID:2340",
        "name": "craniosynostosis",
        "description": "A synostosis that results_in premature fusion located_in skull."
    },
    "synonyms": [
        {
            "id": "DOID:2340",
            "resource": "Disease Ontology",
            "url": "http://disease-ontology.org/term/DOID:2340",
            "name": "Premature closure of cranial sutures",
            "description": ""
        },
        {
            "id": "MONDO:0014128",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014128",
            "name": "craniosynostosis 3",
            "description": "Any craniosynostosis in which the cause of the disease is a mutation in the TCF12 gene."
        },
        {
            "id": "MONDO:0014128",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014128",
            "name": "craniosynostosis 3",
            "description": ""
        },
        {
            "id": "MONDO:0014128",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014128",
            "name": "CRS3",
            "description": ""
        },
        {
            "id": "MONDO:0014128",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014128",
            "name": "TCF12 craniosynostosis",
            "description": ""
        },
        {
            "id": "MONDO:0014128",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014128",
            "name": "craniosynostosis 3; CRS3",
            "description": ""
        },
        {
            "id": "MONDO:0014128",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014128",
            "name": "craniosynostosis caused by mutation in TCF12",
            "description": ""
        },
        {
            "id": "MONDO:0014128",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014128",
            "name": "craniosynostosis type 3",
            "description": ""
        },
        {
            "id": "MONDO:0011481",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011481",
            "name": "craniosynostosis, Boston type",
            "description": "Craniosynostosis, Boston type is a form of syndromic craniosynostosis (see this term), characterized by a highly variable craniosynostosis with frontal bossing, turribrachycephaly and cloverleaf skull anomaly. Hypoplasia of the supraorbital ridges, cleft palate, extra teeth and limb anomalies (triphalangeal thumb, 3-4 syndactyly of the hands, a short first metatarsal, middle phalangeal agenesis in the feet) have also been described. Associated problems include headache, poor vision, and seizures. Intelligence is normal."
        },
        {
            "id": "MONDO:0011481",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011481",
            "name": "Warman-Mulliken-Hayward syndrome",
            "description": ""
        },
        {
            "id": "MONDO:0011481",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011481",
            "name": "craniosynostosis type 2",
            "description": ""
        },
        {
            "id": "MONDO:0011481",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011481",
            "name": "CRS2",
            "description": ""
        },
        {
            "id": "MONDO:0011481",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011481",
            "name": "craniosynostosis 2",
            "description": ""
        },
        {
            "id": "MONDO:0011481",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011481",
            "name": "craniosynostosis Boston type",
            "description": ""
        },
        {
            "id": "MONDO:0011481",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011481",
            "name": "craniosynostosis, Warman type",
            "description": ""
        },
        {
            "id": "MONDO:0011481",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011481",
            "name": "Warman Mulliken Hayward syndrome",
            "description": ""
        },
        {
            "id": "MONDO:0011481",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011481",
            "name": "craniosynostosis Warman type",
            "description": ""
        },
        {
            "id": "MONDO:0011481",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011481",
            "name": "craniosynostosis, Boston-type",
            "description": ""
        },
        {
            "id": "MONDO:0011481",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011481",
            "name": "craniosynostosis 2; CRS2",
            "description": ""
        },
        {
            "id": "MONDO:0010929",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010929",
            "name": "craniosynostosis 4",
            "description": "Any craniosynostosis in which the cause of the disease is a mutation in the ERF gene."
        },
        {
            "id": "MONDO:0010929",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010929",
            "name": "craniosynostosis 4",
            "description": ""
        },
        {
            "id": "MONDO:0010929",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010929",
            "name": "CRS4",
            "description": ""
        },
        {
            "id": "MONDO:0010929",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010929",
            "name": "ERF craniosynostosis",
            "description": ""
        },
        {
            "id": "MONDO:0010929",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010929",
            "name": "craniosynostosis caused by mutation in ERF",
            "description": ""
        },
        {
            "id": "MONDO:0010929",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010929",
            "name": "craniosynostosis 4; CRS4",
            "description": ""
        },
        {
            "id": "MONDO:0010929",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010929",
            "name": "craniosynostosis type 4",
            "description": ""
        },
        {
            "id": "MONDO:0010903",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010903",
            "name": "craniosynostosis, Adelaide type",
            "description": ""
        },
        {
            "id": "MONDO:0010903",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010903",
            "name": "CRSA",
            "description": ""
        },
        {
            "id": "MONDO:0010903",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010903",
            "name": "craniosynostosis, Adelaide type; CRSA",
            "description": ""
        },
        {
            "id": "MONDO:0010903",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010903",
            "name": "craniosynostosis, Adelaide type",
            "description": ""
        },
        {
            "id": "MONDO:0008426",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008426",
            "name": "Shprintzen-Goldberg syndrome",
            "description": "Shprintzen-Goldberg syndrome (SGS) is a very rare genetic disorder characterized by craniosynostosis, craniofacial and skeletal abnormalities, marfanoid habitus, cardiac anomalies, neurological abnormalities, and intellectual disability."
        },
        {
            "id": "MONDO:0008426",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008426",
            "name": "Marfanoid disorder with craniosynostosis type 1",
            "description": ""
        },
        {
            "id": "MONDO:0008426",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008426",
            "name": "Shprintzen-Goldberg craniosynostosis syndrome",
            "description": ""
        },
        {
            "id": "MONDO:0008426",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008426",
            "name": "Marfanoid disorder with craniosynostosis, type 1",
            "description": ""
        },
        {
            "id": "MONDO:0008426",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008426",
            "name": "Marfanoid craniosynostosis syndrome",
            "description": ""
        },
        {
            "id": "MONDO:0008426",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008426",
            "name": "SGS",
            "description": ""
        },
        {
            "id": "MONDO:0008426",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008426",
            "name": "Shprintzen-Goldberg craniosynostosis syndrome; SGS",
            "description": ""
        },
        {
            "id": "MONDO:0008426",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008426",
            "name": "Shprintzen-Goldberg marfanoid syndrome",
            "description": ""
        },
        {
            "id": "MONDO:0008426",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008426",
            "name": "Marfanoid-craniosynostosis syndrome",
            "description": ""
        },
        {
            "id": "MONDO:0008426",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008426",
            "name": "craniosynostosis with arachnodactyly and abdominal hernias",
            "description": ""
        },
        {
            "id": "MONDO:0007399",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007399",
            "name": "craniosynostosis 1",
            "description": ""
        },
        {
            "id": "MONDO:0007399",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007399",
            "name": "craniosynostosis 1; CRS1",
            "description": ""
        },
        {
            "id": "MONDO:0007399",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007399",
            "name": "craniosynostosis type 1",
            "description": ""
        },
        {
            "id": "MONDO:0007399",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007399",
            "name": "craniostenosis",
            "description": ""
        },
        {
            "id": "MONDO:0007399",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007399",
            "name": "craniosynostosis 1",
            "description": ""
        },
        {
            "id": "MONDO:0007399",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007399",
            "name": "CRS1",
            "description": ""
        },
        {
            "id": "MONDO:0007399",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007399",
            "name": "CRS",
            "description": ""
        },
        {
            "id": "MIM:615314",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/615314",
            "name": "Craniosynostosis 3",
            "description": "Craniosynostosis 3"
        },
        {
            "id": "MIM:604757",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/604757",
            "name": "Craniosynostosis 2",
            "description": "Craniosynostosis 2"
        },
        {
            "id": "MIM:600775",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/600775",
            "name": "Craniosynostosis 4",
            "description": "Craniosynostosis 4"
        },
        {
            "id": "MIM:182212",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/182212",
            "name": "Shprintzen-Goldberg craniosynostosis syndrome",
            "description": "Shprintzen-Goldberg craniosynostosis syndrome"
        },
        {
            "id": "MIM:123100",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/123100",
            "name": "Craniosynostosis 1",
            "description": "Craniosynostosis 1"
        }
    ]
}