{ "uniprot_canonical_ac": "A4D1E9-1", "ptm_annotation": [], "sequence": { "header": "sp|A4D1E9-1|GTPBA_HUMAN Isoform 1 of GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=1 CANONICAL=A4D1E9-1", "length": 387, "sequence": "MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIGELNKENDRILVAQGGLGGKLLTNFLPLKGQKRIIHLDLKLIADVGLVGFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLLNLWISDTMSSTEPPSKHAVTTSKMDII" }, "uniprot_id": "C9JNI1_HUMAN", "glycation": [], "keywords": [], "species": [ { "common_name": "Human", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4D1E9", "id": "A4D1E9", "database": "UniProtKB" } ], "name": "Homo sapiens", "taxid": 9606 } ], "reaction_enzymes": [], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/17054726", "type": "PubMed", "id": "17054726" } ], "title": "Human small G proteins, ObgH1, and ObgH2, participate in the maintenance of mitochondria and nucleolar architectures.", "journal": "Genes Cells", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4D1E9", "id": "A4D1E9", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036182.1", "id": "NP_001036182.1", "database": "RefSeq" } ], "authors": "Hirano Y., Takeyasu K., Wada C., Ohniwa R.L., Yoshimura S.H.", "date": "2006" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/20068231", "type": "PubMed", "id": "20068231" } ], "title": "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.", "journal": "Science signaling", "evidence": [ { "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A4D1E9-1", "id": "A4D1E9-1", "database": "iPTMnet" } ], "authors": "Olsen JV, Vermeulen M, Santamaria A, Kumar C, Miller ML, Jensen LJ, Gnad F, Cox J, Jensen TS, Nigg EA, Brunak S, Mann M", "date": "2010" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/22658674", "type": "PubMed", "id": "22658674" } ], "title": "Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.", "journal": "Cell", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036182.1", "id": "NP_001036182.1", "database": "RefSeq" } ], "authors": "Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW", "date": "2012" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/23824729", "type": "PubMed", "id": "23824729" } ], "title": "Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.", "journal": "The American journal of clinical nutrition", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036182.1", "id": "NP_001036182.1", "database": "RefSeq" } ], "authors": "van Meurs JB, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, Cotlarciuc I, Yuan X, Malarstig A, Bandinelli S, Bis JC, Blom H, Brown MJ, Chen C, Chen YD, Clarke RJ, Dehghan A, Erdmann J, Ferrucci L, Hamsten A, Hofman A, Hunter DJ, Goel A, Johnson AD, Kathiresan S, Kampman E, Kiel DP, Kiemeney LA, Chambers JC, Kraft P, Lindemans J, McKnight B, Nelson CP, O'Donnell CJ, Psaty BM, Ridker PM, Rivadeneira F, Rose LM, Seedorf U, Siscovick DS, Schunkert H, Selhub J, Ueland PM, Vollenweider P, Waeber G, Waterworth DM, Watkins H, Witteman JC, den Heijer M, Jacques P, Uitterlinden AG, Kooner JS, Rader DJ, Reilly MP, Mooser V, Chasman DI, Samani NJ, Ahmadi KR", "date": "2013" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/28510447", "type": "PubMed", "id": "28510447" } ], "title": "Synthesis of a Highly Azide-Reactive and Thermosensitive Biofunctional Reagent for Efficient Enrichment and Large-Scale Identification of O-GlcNAc Proteins by Mass Spectrometry.", "journal": "Analytical chemistry", "evidence": [ { "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A4D1E9", "id": "A4D1E9", "database": "O-GlcNAc Database" } ], "authors": "Zhang W, Liu T, Dong H, Bai H, Tian F, Shi Z, Chen M, Wang J, Qin W, Qian X", "date": "2017" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/30085210", "type": "PubMed", "id": "30085210" } ], "title": "The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.", "journal": "Nucleic acids research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036182.1", "id": "NP_001036182.1", "database": "RefSeq" } ], "authors": "Lavdovskaia E, Kolander E, Steube E, Mai MM, Urlaub H, Richter-Dennerlein R", "date": "2018" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/30321378", "type": "PubMed", "id": "30321378" } ], "title": "Human GTPBP10 is required for mitoribosome maturation.", "journal": "Nucleic acids research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036182.1", "id": "NP_001036182.1", "database": "RefSeq" } ], "authors": "Maiti P, Kim HJ, Tu YT, Barrientos A", "date": "2018" } ], "uniprot_ac": "A4D1E9", "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A4D1E9", "type": "synonym", "resource": "RefSeq", "name": "GTPBP10" }, { "url": "https://www.uniprot.org/uniprot/A4D1E9", "type": "recommended", "resource": "UniProtKB", "name": "GTPBP10" }, { "url": "https://www.uniprot.org/uniprot/A4D1E9", "type": "synonym", "resource": "UniProtKB", "name": "OBGH2" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A4D1E9", "type": "synonym", "resource": "RefSeq", "name": "ObgH2; UG0751c10" }, { "url": "https://www.uniprot.org/uniprot/A4D1E9", "type": "synonym", "resource": "UniProtKB", "name": "UG0751c10" } ], "reactions": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A4D1E9#A4D1E9-1", "isoform_ac": "A4D1E9-1", "locus": { "end_pos": 90346742, "strand": "-", "start_pos": 90385151, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000222511", "id": "ENST00000222511", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000222511", "id": "ENSP00000222511", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A4D1E9-1|GTPBA_HUMAN Isoform 1 of GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=1 CANONICAL=A4D1E9-1", "length": 387, "sequence": "MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIGELNKENDRILVAQGGLGGKLLTNFLPLKGQKRIIHLDLKLIADVGLVGFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLLNLWISDTMSSTEPPSKHAVTTSKMDII" } }, { "url": "https://www.uniprot.org/uniprot/A4D1E9#A4D1E9-2", "isoform_ac": "A4D1E9-2", "locus": { "end_pos": 90346742, "strand": "-", "start_pos": 90385151, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000257659", "id": "ENST00000257659", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000257659", "id": "ENSP00000257659", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A4D1E9-2|GTPBA_HUMAN Isoform 2 of GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=1 CANONICAL=A4D1E9-1", "length": 308, "sequence": "MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLLNLWISDTMSSTEPPSKHAVTTSKMDII" } }, { "url": "https://www.uniprot.org/uniprot/A4D1E9#A4D1E9-3", "isoform_ac": "A4D1E9-3", "locus": { "end_pos": 90346742, "strand": "-", "start_pos": 90372183, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000380058", "id": "ENST00000380058", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000369398", "id": "ENSP00000369398", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A4D1E9-3|GTPBA_HUMAN Isoform 3 of GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=1 CANONICAL=A4D1E9-1", "length": 116, "sequence": "MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIDSQMLENPLC" } }, { "url": "https://www.uniprot.org/uniprot/A4D1E9#C9J8R7-1", "isoform_ac": "C9J8R7-1", "locus": { "end_pos": 90340519, "strand": "-", "start_pos": 90377572, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000426366", "id": "ENST00000426366", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000405697", "id": "ENSP00000405697", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|C9J8R7-1|GTPBA_HUMAN Computationally mapped isoform of GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=1 CANONICAL=A4D1E9-1", "length": 210, "sequence": "MRYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIGELNKENDRILVAQGGLGGKLLTNFLPLKGQKRIIHLDLKLIADVGLVGFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHK" } }, { "url": "https://www.uniprot.org/uniprot/A4D1E9#C9JEQ8-1", "isoform_ac": "C9JEQ8-1", "locus": { "end_pos": 90346742, "strand": "-", "start_pos": 90384935, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000417207", "id": "ENST00000417207", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000416596", "id": "ENSP00000416596", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|C9JEQ8-1|C9JEQ8_HUMAN Computationally mapped isoform of GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=8 CANONICAL=A4D1E9-1", "length": 242, "sequence": "MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIVTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERT" } }, { "url": "https://www.uniprot.org/uniprot/A4D1E9#C9JNI1-1", "isoform_ac": "C9JNI1-1", "locus": { "end_pos": 90340519, "strand": "-", "start_pos": 90377572, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000450619", "id": "ENST00000450619", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000389510", "id": "ENSP00000389510", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|C9JNI1-1|GTPBA_HUMAN Computationally mapped isoform of GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=1 CANONICAL=A4D1E9-1", "length": 236, "sequence": "MRTVSLCHPDWSALASSWLTAASTSWAQYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIGELNKENDRILVAQGGLGGKLLTNFLPLKGQKRIIHLDLKLIADVGLVGFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHK" } }, { "url": "https://www.uniprot.org/uniprot/A4D1E9#F8WBB5-1", "isoform_ac": "F8WBB5-1", "locus": { "end_pos": 90340519, "strand": "-", "start_pos": 90372183, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000453512", "id": "ENST00000453512", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000410311", "id": "ENSP00000410311", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F8WBB5-1|GTPBA_HUMAN Computationally mapped isoform of GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=1 CANONICAL=A4D1E9-1", "length": 107, "sequence": "MRYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIDSQMLENPLC" } }, { "url": "https://www.uniprot.org/uniprot/A4D1E9#F8WBY0-1", "isoform_ac": "F8WBY0-1", "locus": { "end_pos": 90340519, "strand": "-", "start_pos": 90355095, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000421719", "id": "ENST00000421719", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000411091", "id": "ENSP00000411091", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F8WBY0-1|F8WBY0_HUMAN Computationally mapped isoform of GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=1 CANONICAL=A4D1E9-1", "length": 70, "sequence": "MRYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKRTQ" } }, { "url": "https://www.uniprot.org/uniprot/A4D1E9#F8WCN4-1", "isoform_ac": "F8WCN4-1", "locus": { "end_pos": 90346742, "strand": "-", "start_pos": 90355095, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000439832", "id": "ENST00000439832", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000416713", "id": "ENSP00000416713", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F8WCN4-1|GTPBA_HUMAN Computationally mapped isoform of GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=1 CANONICAL=A4D1E9-1", "length": 79, "sequence": "MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKRTQ" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:85865", "resource": "KEGG Pathway", "id": "hsa:85865", "name": "" } ], "reaction_participants": [], "function": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036182.1", "annotation": "GTPBP10 primarily ensures proper mtLSU maturation and ultimately serves to coordinate mtSSU and mtLSU accumulation", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036182.1", "id": "NP_001036182.1", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036182.1", "annotation": "Knock-down of ObgH1 by RNAi induced mitochondria elongation, whereas knock-down of ObgH2 resulted in the disorganization of the nucleolar architecture.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036182.1", "id": "NP_001036182.1", "database": "RefSeq" } ] }, { "url": "https://www.uniprot.org/uniprot/A4D1E9#function", "annotation": "May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4D1E9#function", "id": "A4D1E9", "database": "UniProtKB" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036182.1", "annotation": "Our results suggest that GTPBP10 is a ribosome biogenesis factor of the mtLSU required for late stages of maturation.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036182.1", "id": "NP_001036182.1", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "D4A3U1-1", "protein_name": "GTP-binding protein 10", "sequence": { "length": 369, "sequence": "MVRCGCALLRKYGNFIDNLRIFTKGGSGGMGYPRLGGEGGRGGDVWVVAHKNMTLKQLKNKYPQKRFVAGGGANSRVSALKGSKGKDCEVPAPVGVSVTDENGEVLGELNKEKDRILVAKGGLGGKLHTNFLPLKGQKRIIHLDLKVIADVGLVGFPNAGKSSLLSRVSHATPVIASYAFTTLRPELGKIMYNDFKQISVADLPGLIEGAHMNKGMGHKFLKHLERTRQLLFVVDISGFQLSSVTPYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQVKLHELMKQLQKPEDFLHLFEAKMIPEKAIEFQHIIPISAVTGEGIEELKNCIRESLDEQDDKENDAFHNKQLLSLQRSGSAS" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A4D1E9/", "id": "A4D1E9", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/8114", "id": "8114", "database": "MGI" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "gene_name": "Gtpbp10", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q8K013-1", "protein_name": "GTP-binding protein 10", "sequence": { "length": 366, "sequence": "MVRCGCALLRKYGNFIDNLRIFTKGGSGGMGYPRLGGEGGRGGDVWVVAHKNMTLKQLKNKYPQKRFVAGGGANSRVSALQGSKGKDCEVPAPVGISVTDENGQVLGELNKEEDRVLVAKGGLGGKLHTNFLPLKGQKRIVHLDLKVIADVGLVGFPNAGKSSLLSRVSHATPVIADYAFTTLRPELGKIMYNDFKQISVADLPGLIEGAHMNKGMGHKFLKHLERTRQLLFVVDISGFQLSSVTPYRTAFETIILLTKELELYKEELQTKPALLAINKMDLPDAQVKLQELMKQLLSPEDFLHLFETKMIPEKALEFQHIVPISTVTGEGIAELKSCIRKALDEQDGKESDAHRSKQLLNLQSSS" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A4D1E9/", "id": "A4D1E9", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/8114", "id": "8114", "database": "MGI" } ], "common_name": "Mouse", "organism": "Mus musculus", "gene_name": "Gtpbp10", "tax_id": 10090 } ], "interactions": [], "synthesized_glycans": [], "snv": [ { "comment": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.0%).", "sequence_org": "K", "start_pos": 104, "alt_nt": "G", "chr_id": "7", "subjects_positive": "1", "chr_pos": "89983854", "disease": [ { "disease_id": "DOID:11054", "synonyms": [ { "url": "http://disease-ontology.org/term/DOID:11054", "resource": "Disease Ontology", "description": "", "name": "bladder cancer", "id": "DOID:11054" }, { "url": "http://disease-ontology.org/term/DOID:11054", "resource": "Disease Ontology", "description": "", "name": "tumor of the bladder", "id": "DOID:11054" }, { "url": "https://monarchinitiative.org/disease/MONDO:0001187", "resource": "MONDO", "description": "A primary or metastatic malignant neoplasm involving the bladder.", "name": "urinary bladder cancer", "id": "MONDO:0001187" }, { "url": "https://monarchinitiative.org/disease/MONDO:0001187", "resource": "MONDO", "description": "", "name": "urinary bladder malignant neoplasm", "id": "MONDO:0001187" }, { "url": "https://monarchinitiative.org/disease/MONDO:0001187", "resource": "MONDO", 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