{
    "uniprot_canonical_ac": "A2AD83-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2AD83-1|FRMD7_MOUSE Isoform 1 of FERM domain-containing protein 7  OS=Mus musculus OX=10090 GN=Frmd7 PE=1 SV=1 CANONICAL=A2AD83-1", 
        "length": 703, 
        "sequence": "MLHLKVQFLDDSQKIFVVDQKSSGKALFNLSCGHLNLAEKEYFGLEFCSHSGNNVWLELLKPITKQVKNPKEVVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSELGDFHEETVRKHLVQTQYLPSQASLESKIMQFHQQHIGRSPAESDILLLDIARKLDMYGIRPQPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMASRDACKAFWKTCVEYHAFFRLSEEPKSKPKTLLCSKGSSFRYSGRTQRQLLEYGKKGRLKSLPFERKQYPSQYHERQCRSSPDILSDVSKQVEDLRLTYGSSYYRNVNGVHASESMLDSRRRNSAVEVTFAAELEHSKPEAEATSLHPSQSSSSFTFIYADPVFNTDPEPIEFFEERSPLSSFQTTSKFADSHTSKASPARQLTYTDVPYIPCTSQKVDIMPPQVFFYVDKPPQVPRRSLIMAEENMRPDSYVDHSAIKPAKRSPRNMRIKSLQQDLQELQEAMARTSGRSNINVEPEEEDPHLDDAFAYNLQEQTPKRSQSQSDMKTIRFPFGSEFRPLGPCPALTRKTDLFACTFAEQEFPTVLIDQSSAERYVASESSDSESEIIKPDYYFLYGKGTKSPRARIRLSSGSLQLEEEDETISFATPGAEDRTLLKPCNYFLA"
    }, 
    "uniprot_id": "E9PXK8_MOUSE", 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AD83", 
                    "id": "A2AD83", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "reaction_enzymes": [], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/19265863", 
                    "type": "PubMed", 
                    "id": "19265863"
                }
            ], 
            "title": "Frmd7 expression in developing mouse brain.", 
            "journal": "Eye (London, England)", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
                    "id": "NP_001177261.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Self J, Haitchi HM, Griffiths H, Holgate ST, Davies DE, Lotery A", 
            "date": "2010"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/19892780", 
                    "type": "PubMed", 
                    "id": "19892780"
                }
            ], 
            "title": "The nystagmus-associated FRMD7 gene regulates neuronal outgrowth and development.", 
            "journal": "Hum. Mol. Genet.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AD83", 
                    "id": "A2AD83", 
                    "database": "UniProtKB"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
                    "id": "NP_001177261.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Crosier M., Lindsay S., Salomoni P., Bartesaghi S., Betts-Henderson J., Chen H.L., Gottlob I., Nicotera P.", 
            "date": "2010"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/22128244", 
                    "type": "PubMed", 
                    "id": "22128244"
                }
            ], 
            "title": "Identification of a novel FRMD7 splice variant and functional analysis of two FRMD7 transcripts during human NT2 cell differentiation.", 
            "journal": "Molecular vision", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
                    "id": "NP_001177261.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Li Y, Pu J, Liu Z, Xu S, Jin F, Zhu L, Tian J, Luo J, Zhang B", 
            "date": "2011"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/26711119", 
                    "type": "PubMed", 
                    "id": "26711119"
                }
            ], 
            "title": "Congenital Nystagmus Gene FRMD7 Is Necessary for Establishing a Neuronal Circuit Asymmetry for Direction Selectivity.", 
            "journal": "Neuron", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
                    "id": "NP_001177261.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Yonehara K, Fiscella M, Drinnenberg A, Esposti F, Trenholm S, Krol J, Franke F, Scherf BG, Kusnyerik A, Muller J, Szabo A, Juttner J, Cordoba F, Reddy AP, Nemeth J, Nagy ZZ, Munier F, Hierlemann A, Roska B", 
            "date": "2016"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/28530661", 
                    "type": "PubMed", 
                    "id": "28530661"
                }
            ], 
            "title": "Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex.", 
            "journal": "Nature neuroscience", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
                    "id": "NP_001177261.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Hillier D, Fiscella M, Drinnenberg A, Trenholm S, Rompani SB, Raics Z, Katona G, Juettner J, Hierlemann A, Rozsa B, Roska B", 
            "date": "2017"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/31291246", 
                    "type": "PubMed", 
                    "id": "31291246"
                }
            ], 
            "title": "Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing.", 
            "journal": "PloS one", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
                    "id": "NP_001177261.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Sah RK, Yang A, Bah FB, Adlat S, Bohio AA, Oo ZM, Wang C, Myint MZZ, Bahadar N, Zhang L, Feng X, Zheng Y", 
            "date": "2019"
        }
    ], 
    "uniprot_ac": "A2AD83", 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2AD83", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "EG665849; Gm1533"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2AD83", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Frmd7"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AD83", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Frmd7"
        }
    ], 
    "reactions": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AD83#A2AD83-1", 
            "isoform_ac": "A2AD83-1", 
            "locus": {
                "end_pos": 50895183, 
                "strand": "+", 
                "start_pos": 50942710, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000060650", 
                        "id": "ENSMUST00000060650", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000057103", 
                        "id": "ENSMUSP00000057103", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2AD83-1|FRMD7_MOUSE Isoform 1 of FERM domain-containing protein 7  OS=Mus musculus OX=10090 GN=Frmd7 PE=1 SV=1 CANONICAL=A2AD83-1", 
                "length": 703, 
                "sequence": "MLHLKVQFLDDSQKIFVVDQKSSGKALFNLSCGHLNLAEKEYFGLEFCSHSGNNVWLELLKPITKQVKNPKEVVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSELGDFHEETVRKHLVQTQYLPSQASLESKIMQFHQQHIGRSPAESDILLLDIARKLDMYGIRPQPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMASRDACKAFWKTCVEYHAFFRLSEEPKSKPKTLLCSKGSSFRYSGRTQRQLLEYGKKGRLKSLPFERKQYPSQYHERQCRSSPDILSDVSKQVEDLRLTYGSSYYRNVNGVHASESMLDSRRRNSAVEVTFAAELEHSKPEAEATSLHPSQSSSSFTFIYADPVFNTDPEPIEFFEERSPLSSFQTTSKFADSHTSKASPARQLTYTDVPYIPCTSQKVDIMPPQVFFYVDKPPQVPRRSLIMAEENMRPDSYVDHSAIKPAKRSPRNMRIKSLQQDLQELQEAMARTSGRSNINVEPEEEDPHLDDAFAYNLQEQTPKRSQSQSDMKTIRFPFGSEFRPLGPCPALTRKTDLFACTFAEQEFPTVLIDQSSAERYVASESSDSESEIIKPDYYFLYGKGTKSPRARIRLSSGSLQLEEEDETISFATPGAEDRTLLKPCNYFLA"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AD83#E9PXK8-1", 
            "isoform_ac": "E9PXK8-1", 
            "locus": {
                "end_pos": 50909829, 
                "strand": "+", 
                "start_pos": 50942710, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000164311", 
                        "id": "ENSMUST00000164311", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000126628", 
                        "id": "ENSMUSP00000126628", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|E9PXK8-1|E9PXK8_MOUSE Computationally mapped isoform of FERM domain-containing protein 7  OS=Mus musculus OX=10090 GN=Frmd7 PE=4 SV=1 CANONICAL=A2AD83-1", 
                "length": 85, 
                "sequence": "MLHLKVQFLDDSQKIFVVDQKSSGKALFNLSCGHLNLAEKEYFGLEFCSHSGNNVWLELLKPITKQVKSKYGRSLKGWGIFLLFK"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:385354", 
            "resource": "KEGG Pathway", 
            "id": "mmu:385354", 
            "name": ""
        }
    ], 
    "reaction_participants": [], 
    "function": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
            "annotation": "A novel splice variant of FRMD7 (FRMD7-S) with a shortened exon 4 relative to the original form of FRMD7 (FRMD7-FL) was identified from the cDNA of the human NT2 cell line and mouse fetal brain.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
                    "id": "NP_001177261.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
            "annotation": "FRMD7 as a key regulator in establishing a neuronal circuit asymmetry", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
                    "id": "NP_001177261.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
            "annotation": "FRMD7 expression is spatially and temporally regulated in human and mouse brain during embryonic and fetal development.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
                    "id": "NP_001177261.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AD83#function", 
            "annotation": "Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AD83#function", 
                    "id": "A2AD83", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "F1M1Y3-1", 
            "protein_name": "FERM domain-containing 7", 
            "sequence": {
                "length": 703, 
                "sequence": "MLHLKVQFLDDSQKIFVVDQKSSGKALFNLSCSHLNLAEKEYFGLEFCSHSGHNVWLELLKPITKQVKNPKEVVFKFIVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSELGDFHEEMVRKHLVQTQYLPSQACLESKIMQFHQQHIGRSPAESDILLLDIARKLDMYGIRPQPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMASRDACKAFWKTCVEYHAFFRLSEEPKSKPKTLLCSKGSSFRYSGRTQRQLLEYGKKGRLKSLPFERKQYPSQYHERQCRSSPDILSDVSKQVEDLRLTYGSSYYRNVNGVHASEPMLDGRRRNSAVEVTFAAELEHSKPEAEAASLHPSQSSSSFTFIYADPVFNTDPEPIDFFEERSPLSSFQTNSKFVDGHTSKVSPARQLTYTDVPYIPCTSQKVDIMPPQVFFYVDKPPQVPRRSLMMAEESMRPDSYVDPSAIKPAKRSPRNMRIKSLQQDLQELQEAMARTSGRSNINVEPEEEDPHLDDAFAYNLQEQTPKRSQSQSDMKTIRFPFGSEFRPLGPCPALTRKTDLFTCTFAEQEFPTVLMDQSSAERYVASESSDSESEILKTDYYSLYGKGTKSPRARIRLSSGSLQLEEEDEAISFGTPGAEDRTLLKPCNYFLA"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A2AD83/", 
                    "id": "A2AD83", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/18855", 
                    "id": "18855", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Rat", 
            "organism": "Rattus norvegicus", 
            "gene_name": "Frmd7", 
            "tax_id": 10116
        }, 
        {
            "uniprot_canonical_ac": "Q6ZUT3-1", 
            "protein_name": "FERM domain-containing protein 7", 
            "sequence": {
                "length": 714, 
                "sequence": "MLHLKVQFLDDSQKIFVVDQKSSGKALFNLSCSHLNLAEKEYFGLEFCSHSGNNVWLELLKPITKQVKNPKEIVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSELGDFHEETDRKHLAQTRYLPNQDCLEGKIMHFHQKHIGRSPAESDILLLDIARKLDMYGIRPHPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMASRDACKAFWKTCVEYHAFFRLSEEPKSKPKTLLCSKGSSFRYSGRTQRQLLEYGRKGRLKSLPFERKHYPSQYHERQCRSSPDLLSDVSKQVEDLRLAYGGGYYQNVNGVHASEPVLESRRRNSALEVTFATELEHSKPEADPTLLHQSQSSSSFPFIYMDPVFNTEPNPNPDPRDIFSERSSLSSFQTSCKFSGNHMSIYSGLTSKVRPAKQLTYTDVPYIPCTGQQVGIMPPQVFFYVDKPPQVPRWSPIRAEERTSPHSYVEPTAMKPAERSPRNIRMKSFQQDLQVLQEAIARTSGRSNINVGLEEEDPNLEDAFVCNIQEQTPKRSQSQSDMKTIRFPFGSEFRPLGPCPALSHKADLFTDMFAEQELPAVLMDQSTAERYVASESSDSESEILKPDYYALYGKEIRSPMARIRLSSGSLQLDEEDEDAYFNTPTAEDRTSLKPCNYFLA"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A2AD83/", 
                    "id": "A2AD83", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/18855", 
                    "id": "18855", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "FRMD7", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
        "ac": "NP_001177261.1", 
        "name": "FERM domain-containing protein 7", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", 
                        "pmid": "19892780", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AD83", 
                                "id": "A2AD83", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "growth cone", 
                        "id": "GO:0030426"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", 
                        "pmid": "19892780", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AD83", 
                                "id": "A2AD83", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "neuronal cell body", 
                        "id": "GO:0043025"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", 
                        "pmid": "19892780", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AD83", 
                                "id": "A2AD83", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "neuron projection", 
                        "id": "GO:0043005"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AD83", 
                                "id": "A2AD83", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoskeleton", 
                        "id": "GO:0005856"
                    }
                ], 
                "total": 4, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051057", 
                        "pmid": "23967341", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AD83", 
                                "id": "A2AD83", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of small GTPase mediated signal transduction", 
                        "id": "GO:0051057"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032091", 
                        "pmid": "23967341", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AD83", 
                                "id": "A2AD83", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of protein binding", 
                        "id": "GO:0032091"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010975", 
                        "pmid": "19892780", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AD83", 
                                "id": "A2AD83", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "regulation of neuron projection development", 
                        "id": "GO:0010975"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010592", 
                        "pmid": "23967341", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AD83", 
                                "id": "A2AD83", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of lamellipodium assembly", 
                        "id": "GO:0010592"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", 
                        "pmid": "23967341", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AD83", 
                                "id": "A2AD83", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of stress fiber assembly", 
                        "id": "GO:0051497"
                    }
                ], 
                "total": 5, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 118, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 116
        }, 
        {
            "end_pos": 31, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 29
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000036131", 
            "id": "ENSMUSG00000036131", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13193", 
            "id": "cd13193", 
            "database": "CDD"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", 
            "id": "cd14473", 
            "database": "CDD"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/385354", 
            "id": "385354", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", 
            "id": "IPR000299", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", 
            "id": "IPR011993", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", 
            "id": "IPR014352", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014847", 
            "id": "IPR014847", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", 
            "id": "IPR018979", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018980", 
            "id": "IPR018980", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747", 
            "id": "IPR019747", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", 
            "id": "IPR019748", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", 
            "id": "IPR019749", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", 
            "id": "IPR029071", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", 
            "id": "IPR035963", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR041788", 
            "id": "IPR041788", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:385354", 
            "id": "mmu:385354", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:2686379", 
            "id": "2686379", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/DIMPPQV/", 
            "id": "DIMPPQV", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=476668at2759", 
            "id": "476668at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00373", 
            "id": "PF00373", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF08736", 
            "id": "PF08736", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF09379", 
            "id": "PF09379", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF09380", 
            "id": "PF09380", 
            "database": "Pfam"
        }, 
        {
            "url": "http://purl.obolibrary.org/obo/PR_PR_A2AD83", 
            "id": "PR_A2AD83", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261", 
            "id": "NP_001177261", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177261.1", 
            "id": "NP_001177261.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AD83", 
            "id": "A2AD83", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AD83-1", 
            "id": "A2AD83-1", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/E9PXK8", 
            "id": "E9PXK8", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/E9PXK8-1", 
            "id": "E9PXK8-1", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [
        {
            "disease_id": "DOID:0111790", 
            "synonyms": [
                {
                    "url": "http://disease-ontology.org/term/DOID:0111790", 
                    "resource": "Disease Ontology", 
                    "description": "", 
                    "name": "X-linked infantile nystagmus 1", 
                    "id": "DOID:0111790"
                }, 
                {
                    "url": "http://disease-ontology.org/term/DOID:0111790", 
                    "resource": "Disease Ontology", 
                    "description": "", 
                    "name": "NYS1", 
                    "id": "DOID:0111790"
                }, 
                {
                    "url": "http://disease-ontology.org/term/DOID:0111790", 
                    "resource": "Disease Ontology", 
                    "description": "", 
                    "name": "congenital motor nystagmus 1", 
                    "id": "DOID:0111790"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "Any congenital nystagmus in which the cause of the disease is a mutation in the FRMD7 gene.", 
                    "name": "nystagmus 1, congenital, X-linked", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Nystagmus, infantile idiopathic, formerly", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "congenital nystagmus caused by mutation in FRMD7", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "NYS1", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Nystagmus, infantile periodic alternating, X-linked", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Nystagmus 1, infantile, X-linked", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Nystagmus, infantile idiopathic", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "nystagmus 1, congenital, X-linked", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Xlpan", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Nystagmus, congenital motor, 1", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "NYSTAGMUS 1, congenital, X-linked; NYS1", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Nystagmus 1, congenital, X- linked", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0010693", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "FRMD7 congenital nystagmus", 
                    "id": "MONDO:0010693"
                }, 
                {
                    "url": "https://www.omim.org/entry/310700", 
                    "resource": "MIM", 
                    "description": "Nystagmus congenital X-linked 1", 
                    "name": "Nystagmus congenital X-linked 1", 
                    "id": "MIM:310700"
                }
            ], 
            "recommended_name": {
                "url": "http://disease-ontology.org/term/DOID:0111790", 
                "resource": "Disease Ontology", 
                "description": "A congenital nystagmus that has_material_basis_in mutation in FRMD7 on chromosome Xq26.2.", 
                "name": "congenital nystagmus 1", 
                "id": "DOID:0111790"
            }, 
            "evidence": [
                {
                    "url": "https://www.alliancegenome.org/gene/0111790#disease-associations", 
                    "id": "0111790", 
                    "database": "Alliance of Genome Resources"
                }
            ]
        }
    ], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 80330.0, 
        "chemical_mass": 80330.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AD83", 
            "name": "Frmd7", 
            "locus": {
                "end_pos": 50895180, 
                "strand": "-", 
                "start_pos": 50942710, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000036131", 
                        "id": "ENSMUSG00000036131", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2AD83", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "FERM domain-containing protein 7"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AD83#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "FERM domain-containing protein 7"
        }
    ]
}