{ "uniprot_canonical_ac": "A2AAJ9-1", "ptm_annotation": [ { "annotation": "Autophosphorylated by protein kinase domain 1 and 2.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/pubmed/23392350", "id": "23392350", "database": "PubMed" } ] }, { "annotation": "Two small isoforms, one probably containing protein kinase domain 2 and a partial protein kinase domain 1 and one containing only protein kinase domain 2, are glycosylated.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/pubmed/23392350", "id": "23392350", "database": "PubMed" } ] } ], "sequence": { "header": "sp|A2AAJ9-1|OBSCN_MOUSE Isoform 1 of Obscurin OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=3 CANONICAL=A2AAJ9-1", "length": 8886, "sequence": "MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFKKRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCVSAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKFVANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQDITDGYRDWGPAGPQKHMCKCAGAKIARYLGSSCYRFLQYDKGVWHWLEAALDTRQGKGTSSCSLHEKPKLVFAKGQQAHSEVKAEAGNSATLSCEVTQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLMFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVADTRLMFAKEQQARTEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEGVHTSARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPVDVRWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRFRESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRALPAKFKDSLKNEEATEGTTATLSCELSKAAPVTWKKGPKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQEKTSATLTVRGLPAKFIEDLRSQEATEGATAILRCELSKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSSLPTKFTEGLRNEEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPSRFIEDLRSQEATEGTMATLRCQMSKTAPVEWKKGSETLRDGGRYSLRQDGPVCELQICDLAVEDAGEYSCVCGQEKTSATLSIKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKKEEATEGTMVTLRCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCELQIRDLAVEDAGEYLCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKALPPRFIEDLRSQEAREGTVATLRCRMSKAAPVEWRKGSETLKDGDRYSLRQEGNLCELQIRDLAVEDTEEYSCVCGQEKTSATLSVKALPAKFIEDLRSQEAPESSTVTLRCKLSKKASVVWKKGSETLRNGARYSLRQDGAVCELEIRDLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQNLQAEEGSMASLRCELSVPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADGCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTVRVPEVTVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRGWRLEVLEPPHDASVKAGMQVRFTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGEVTFAARDAVASARLSVLALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAPAPETRQAVVGEDICLELEVAADGGEVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEYRCGPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDSRVQHLRQEAEETAPDLSEGYSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGGPGISPLASKHEAQVTTSVKPQKQQEPVVPTCPPPGDLSAADLMDPSLDKAAVKIQAAFKGYKVRKEMKQQEGPVFSRTFGDTEAQVGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYTCQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEELFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGIGVEISLGEQGPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMSESAGFADLVGQSKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQVPGGDSDEETKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKLSPEWGPTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLERSPRVPAAVASQKTVIFRNVQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGRVQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEDTSVEGSAHSAQDGADQQAASVLWRLLGSEALGPSPGDLPNTRQSEPPAFEEAASQIPGAASGTPEVSQPGTHKGLEQETTSSGSQGWTVPIRVEGTAWPGAGTGQLLLDVHSQVIMETTQRTYVCQAPDTGVTRAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELLVHGGDKLDAENQVYRRKLHSFYDVQEEIGRGVFGFVKRVQHKGNKMFCAAKFIPLRSKTRAQAYQERDILATLGHPLVTGLLDQFETRKTLILILELCSSEELLDRLFKKGVVTEAEVKVYIQQLVEGLHYLHSHGILHLDIKPPNILMVHPAREDIKICDFGFAQKITPSEPQYSKYGSPEFVSPEIIEQNPVSEGSDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPTAAHLSEDAKDFIKATLQRTPRARPSTSQCLAHPWFLKSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSILVMRSIPELLQGPPDSPSLGVARHLRGEASGASSSSSSSDNELAPFARAKSLPPSPVTHSPLLHPRGFLRPSASLPEETEASMPTADAAVPASPQSAGPPASPGCVPRHSVISSLFYQQAGEGAERGNKTSGAKRHPARRRHLLKGGYIARALPGLREPLMEYSLLEEEAAREEQASLMTKTPSFETALRLPSSSVREVPGRSHSLDNPPVTTGPSPEACKEQLLFPPSTGLTHETTAKDRGHKEGFLQESVPFPPMSGDSRPGKQEGSSQDSCRGKPASSCHSELGSGSQEGCGPPSSQSLGSLPPQSLKKELSTSCGPLFSEQPQAAPFPTQVSPLLGSEKEPQDGSLSEGPVPVPSSSPGSASQVDASLDTEGLSEAGDTCDFTPPPQRPQEQATTRKFSLESRGGYAGVAGYGTFAFGGDAGGMLGQGPLWARMAWAVSQSSEEQDEAATESPQPLESLGPIAEASGVPLRTSPSLTPWEEVEQVSLVQIRDLSGDAEAADTISLDISEVDPAYLNLSDLYDIKYLPFEFMIFRRVPKPIEQPESPGSETEAGQGLADFLEEAAWPWPGELGLRAGLEITEEPEEPGDLEALLGEAAVGRKRKWSPSRGLFQFPGRCLSGEEPVELGLRQRVKASMAHISRILKGRPEGPEREGPPRKKAGLASFRLSGLKGRDQELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKPVESCGPVTYIVQCCIEGGSWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPYSSPSEQVLLGGPNHLASEEESSRGRPAQLLPSTKTFAFQMQIRRGRFSVVRQCREKASGRALAAKIVPYQPEDKTAVLREYEALKRLHHPHLAQLHAAYLSPRHLVLILELCSGPELLPSLAERESYSESDVKDYLWQMLSATQYLHAQHILHLDLRSENMMVTEYNLLKVIDLGNAQSLDQEKVPAPENFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSGEYPESSEGTRDLQKGLRKGLIRLSRCYAGLSGGAVAFLQSSLCAQPWGRPCASTCLQCGWLTEEGPTGSRPTPVTFPTVRLRAFVREREKRRALLYKKHNLAQVR" }, "uniprot_id": "E9QQ96_MOUSE", "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "reaction_enzymes": [ { "gene_name": "SIK1B", "uniprot_ac": "A0A0B4J2F2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0B4J2F2", "id": "A0A0B4J2F2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0B4J2F2", "id": "A0A0B4J2F2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Dyrk4", "uniprot_ac": "A0A0G2JU41", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JU41", "id": "A0A0G2JU41", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JU41", "id": "A0A0G2JU41", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "Mast3", "uniprot_ac": "A0A0G2JVL3", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JVL3", "id": "A0A0G2JVL3", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JVL3", "id": "A0A0G2JVL3", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "", "uniprot_ac": "A0A0G2JZW9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JZW9", "id": "A0A0G2JZW9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JZW9", "id": "A0A0G2JZW9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Mast2", "uniprot_ac": "A0A0G2K212", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K212", "id": "A0A0G2K212", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K212", "id": "A0A0G2K212", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Ern1", "uniprot_ac": "A0A0G2K2H4", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Wnk3", "uniprot_ac": "A0A0G2K2Y2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2Y2", "id": "A0A0G2K2Y2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2Y2", "id": "A0A0G2K2Y2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Pik3ca", "uniprot_ac": "A0A0G2K344", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K344", "id": "A0A0G2K344", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K344", "id": "A0A0G2K344", "database": "UniProtKB" } ], "ec_number": "2.7.1.153", "activity": "ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K344", "id": "A0A0G2K344", "database": "UniProtKB" } ], "ec_number": "2.7.1.153", "activity": "" } ] }, { "gene_name": "Rps6ka5", "uniprot_ac": "A0A0G2K366", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K366", "id": "A0A0G2K366", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K366", "id": "A0A0G2K366", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Dapk1", "uniprot_ac": "A0A0G2K5V8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K5V8", "id": "A0A0G2K5V8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K5V8", "id": "A0A0G2K5V8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Obscn", "uniprot_ac": "A0A0G2K8N1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K8N1", "id": "A0A0G2K8N1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K8N1", "id": "A0A0G2K8N1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Dyrk1b", "uniprot_ac": "A0A0G2KAP6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KAP6", "id": "A0A0G2KAP6", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KAP6", "id": "A0A0G2KAP6", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "Rps6kc1", "uniprot_ac": "A0A0G2KB60", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KB60", "id": "A0A0G2KB60", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KB60", "id": "A0A0G2KB60", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Gm7168", "uniprot_ac": "A0AUV4", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0AUV4", "id": "A0AUV4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0AUV4", "id": "A0AUV4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Smok", "uniprot_ac": "A1A5Q6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q6", "id": "A1A5Q6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q6", "id": "A1A5Q6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Obscn", "uniprot_ac": "A2AAJ9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Map3k15", "uniprot_ac": "A2AQW0", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQW0", "id": "A2AQW0", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "ATP + a protein = ADP + a 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"activity": "" } ] }, { "gene_name": "Smoktcr", "uniprot_ac": "A2KF29", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2KF29", "id": "A2KF29", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2KF29", "id": "A2KF29", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Hipk1", "uniprot_ac": "A4L9P5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4L9P5", "id": "A4L9P5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4L9P5", "id": "A4L9P5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Stk24", "uniprot_ac": "B0LT89", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/B0LT89", "id": "B0LT89", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/B0LT89", "id": "B0LT89", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Sbk2", "uniprot_ac": "B1WBU5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/B1WBU5", "id": "B1WBU5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/B1WBU5", "id": "B1WBU5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Brsk1", "uniprot_ac": "B2DD29", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/B2DD29", "id": "B2DD29", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": 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"activity": "" } ] }, { "gene_name": "Cdc42bpg", "uniprot_ac": "D3Z837", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3Z837", "id": "D3Z837", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3Z837", "id": "D3Z837", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Rps6ka3", "uniprot_ac": "D3Z8E0", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3Z8E0", "id": "D3Z8E0", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3Z8E0", "id": "D3Z8E0", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Map4k1", "uniprot_ac": "D3Z8I4", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3Z8I4", "id": "D3Z8I4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3Z8I4", "id": "D3Z8I4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Nek7", "uniprot_ac": "D3ZBE5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZBE5", "id": "D3ZBE5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZBE5", "id": "D3ZBE5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Tp53rk", "uniprot_ac": "D3ZCD7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZCD7", "id": "D3ZCD7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZCD7", "id": "D3ZCD7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Map3k6", "uniprot_ac": "D3ZFL3", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZFL3", "id": "D3ZFL3", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZFL3", "id": "D3ZFL3", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "" } ] }, { "gene_name": "Map3k10", "uniprot_ac": "D3ZG83", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZG83", "id": "D3ZG83", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZG83", "id": "D3ZG83", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "" } ] }, { "gene_name": "Nek8", "uniprot_ac": "D3ZGQ5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZGQ5", "id": "D3ZGQ5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZGQ5", "id": "D3ZGQ5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Map4k5", "uniprot_ac": "D3ZHL6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZHL6", "id": "D3ZHL6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZHL6", "id": "D3ZHL6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Ulk3", "uniprot_ac": "D3ZHP7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZHP7", "id": "D3ZHP7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZHP7", "id": "D3ZHP7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "LOC685619", "uniprot_ac": "D3ZL21", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZL21", "id": "D3ZL21", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZL21", "id": "D3ZL21", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Ulk1", "uniprot_ac": "D3ZMG0", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZMG0", "id": "D3ZMG0", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZMG0", "id": "D3ZMG0", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Wnk2", "uniprot_ac": "D3ZMJ7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZMJ7", "id": "D3ZMJ7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZMJ7", "id": "D3ZMJ7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Brsk2", "uniprot_ac": "D3ZML2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZML2", "id": "D3ZML2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZML2", "id": "D3ZML2", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "ATP + [tau protein] = ADP + [tau protein] phosphate." }, { "evidence": [ { "url": 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"" } ] }, { "gene_name": "Pkn2", "uniprot_ac": "O08874", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O08874", "id": "O08874", "database": "UniProtKB" } ], "ec_number": "2.7.11.13", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O08874", "id": "O08874", "database": "UniProtKB" } ], "ec_number": "2.7.11.13", "activity": "" } ] }, { "gene_name": "Dclk1", "uniprot_ac": "O08875", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O08875", "id": "O08875", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O08875", "id": "O08875", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Bub1", "uniprot_ac": "O08901", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O08901", "id": "O08901", "database": 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O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O09110", "id": "O09110", "database": "UniProtKB" } ], "ec_number": "2.7.12.2", "activity": "" } ] }, { "gene_name": "CIT", "uniprot_ac": "O14578", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O14578", "id": "O14578", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O14578", "id": "O14578", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "RIOK3", "uniprot_ac": "O14730", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O14730", "id": "O14730", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O14730", "id": "O14730", "database": 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"IKBKB", "uniprot_ac": "O14920", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O14920", "id": "O14920", "database": "UniProtKB" } ], "ec_number": "2.7.11.10", "activity": "ATP + [I-kappa-B protein] = ADP + [I-kappa-B phosphoprotein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O14920", "id": "O14920", "database": "UniProtKB" } ], "ec_number": "2.7.11.10", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O14920", "id": "O14920", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." } ] }, { "gene_name": "CASK", "uniprot_ac": "O14936", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O14936", "id": "O14936", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/O14936", "id": "O14936", "database": "UniProtKB" } ], 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"" } ] }, { "gene_name": "CDK11B", "uniprot_ac": "P21127", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P21127", "id": "P21127", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P21127", "id": "P21127", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "TAF1", "uniprot_ac": "P21675", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P21675", "id": "P21675", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P21675", "id": "P21675", "database": "UniProtKB" } ], "ec_number": "2.3.1.48", "activity": "Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P21675", "id": "P21675", 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"evidence": [ { "url": "https://www.uniprot.org/uniprot/P22518", "id": "P22518", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "PRKACG", "uniprot_ac": "P22612", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P22612", "id": "P22612", "database": "UniProtKB" } ], "ec_number": "2.7.11.11", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P22612", "id": "P22612", "database": "UniProtKB" } ], "ec_number": "2.7.11.11", "activity": "" } ] }, { "gene_name": "PRKACB", "uniprot_ac": "P22694", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P22694", "id": "P22694", "database": "UniProtKB" } ], "ec_number": "2.7.11.11", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P22694", "id": "P22694", "database": "UniProtKB" } ], "ec_number": "2.7.11.11", "activity": "" } ] }, { 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"P39951", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P39951", "id": "P39951", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P39951", "id": "P39951", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P39951", "id": "P39951", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P39951", "id": "P39951", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "MAP3K8", "uniprot_ac": "P41279", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P41279", "id": "P41279", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "ATP + a 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"activity": "" } ] }, { "gene_name": "MTOR", "uniprot_ac": "P42345", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P42345", "id": "P42345", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P42345", "id": "P42345", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Mtor", "uniprot_ac": "P42346", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P42346", "id": "P42346", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P42346", "id": "P42346", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "MAPK8", "uniprot_ac": "P45983", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P45983", "id": "P45983", 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O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P45985", "id": "P45985", "database": "UniProtKB" } ], "ec_number": "2.7.12.2", "activity": "" } ] }, { "gene_name": "MAP2K3", "uniprot_ac": "P46734", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P46734", "id": "P46734", "database": "UniProtKB" } ], "ec_number": "2.7.12.2", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P46734", "id": "P46734", "database": "UniProtKB" } ], "ec_number": "2.7.12.2", "activity": "" } ] }, { "gene_name": "Cdk11b", "uniprot_ac": "P46892", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P46892", "id": "P46892", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." } ] }, { "gene_name": "Akt1", "uniprot_ac": "P47196", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P47196", "id": "P47196", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P47196", "id": "P47196", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Akt2", "uniprot_ac": "P47197", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P47197", "id": "P47197", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P47197", "id": "P47197", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Map2k4", "uniprot_ac": "P47809", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P47809", "id": "P47809", "database": "UniProtKB" } ], "ec_number": "2.7.12.2", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P47809", "id": "P47809", "database": "UniProtKB" } ], "ec_number": "2.7.12.2", "activity": "" } ] }, { "gene_name": "Mapk14", "uniprot_ac": "P47811", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P47811", "id": "P47811", "database": "UniProtKB" } ], "ec_number": "2.7.11.24", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P47811", "id": "P47811", "database": "UniProtKB" } ], "ec_number": "2.7.11.24", "activity": "" } ] }, { "gene_name": "CSNK1A1", "uniprot_ac": "P48729", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P48729", "id": "P48729", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a 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"url": "https://www.uniprot.org/uniprot/P49137", "id": "P49137", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49137", "id": "P49137", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Mapkapk2", "uniprot_ac": "P49138", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49138", "id": "P49138", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49138", "id": "P49138", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Mapk8", "uniprot_ac": "P49185", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49185", "id": "P49185", "database": "UniProtKB" } ], "ec_number": "2.7.11.24", "activity": "ATP + a protein = ADP + a 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"activity": "" } ] }, { "gene_name": "CDK8", "uniprot_ac": "P49336", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49336", "id": "P49336", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49336", "id": "P49336", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49336", "id": "P49336", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49336", "id": "P49336", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "" } ] }, { "gene_name": "Cdk5", "uniprot_ac": "P49615", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49615", "id": "P49615", "database": 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O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49759", "id": "P49759", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "CLK2", "uniprot_ac": "P49760", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49760", "id": "P49760", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49760", "id": "P49760", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "CLK3", "uniprot_ac": "P49761", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49761", "id": "P49761", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49761", "id": "P49761", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "GSK3A", "uniprot_ac": "P49840", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49840", "id": "P49840", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49840", "id": "P49840", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "ATP + [tau protein] = ADP + [tau protein] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49840", "id": "P49840", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "" } ] }, { "gene_name": "GSK3B", "uniprot_ac": "P49841", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49841", "id": "P49841", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49841", "id": "P49841", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "ATP + [tau protein] = ADP + [tau protein] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49841", "id": "P49841", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "" } ] }, { "gene_name": "STK19", "uniprot_ac": "P49842", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49842", "id": "P49842", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P49842", "id": "P49842", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "CDK7", "uniprot_ac": "P50613", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P50613", "id": "P50613", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P50613", "id": "P50613", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P50613", "id": "P50613", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P50613", "id": "P50613", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "CDK9", "uniprot_ac": "P50750", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P50750", "id": "P50750", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P50750", "id": "P50750", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P50750", "id": "P50750", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P50750", "id": "P50750", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "IRAK1", "uniprot_ac": "P51617", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51617", "id": "P51617", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51617", "id": "P51617", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "RPS6KA3", "uniprot_ac": "P51812", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51812", "id": "P51812", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51812", "id": "P51812", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "PRKX", "uniprot_ac": "P51817", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51817", "id": "P51817", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51817", "id": "P51817", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Cdk7", "uniprot_ac": "P51952", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51952", "id": "P51952", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51952", "id": "P51952", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51952", "id": "P51952", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51952", "id": "P51952", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "Nek1", "uniprot_ac": "P51954", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51954", "id": "P51954", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51954", "id": "P51954", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "NEK2", "uniprot_ac": "P51955", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51955", "id": "P51955", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51955", "id": "P51955", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "NEK3", "uniprot_ac": "P51956", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51956", "id": "P51956", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51956", "id": "P51956", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "NEK4", "uniprot_ac": "P51957", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51957", "id": "P51957", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P51957", "id": "P51957", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "MAP2K6", "uniprot_ac": "P52564", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P52564", "id": "P52564", "database": "UniProtKB" } ], "ec_number": "2.7.12.2", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P52564", "id": "P52564", "database": "UniProtKB" } ], "ec_number": "2.7.12.2", "activity": "" } ] }, { "gene_name": "Map3k1", "uniprot_ac": "P53349", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53349", "id": "P53349", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53349", "id": "P53349", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "" } ] }, { "gene_name": "PLK1", "uniprot_ac": "P53350", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53350", "id": "P53350", "database": "UniProtKB" } ], "ec_number": "2.7.11.21", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53350", "id": "P53350", "database": "UniProtKB" } ], "ec_number": "2.7.11.21", "activity": "" } ] }, { "gene_name": "Plk2", "uniprot_ac": "P53351", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53351", "id": "P53351", "database": "UniProtKB" } ], "ec_number": "2.7.11.21", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53351", "id": "P53351", "database": "UniProtKB" } ], "ec_number": "2.7.11.21", "activity": "" } ] }, { "gene_name": "DAPK1", "uniprot_ac": "P53355", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53355", "id": "P53355", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53355", "id": "P53355", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "LIMK1", "uniprot_ac": "P53667", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53667", "id": "P53667", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53667", "id": "P53667", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Limk1", "uniprot_ac": "P53668", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53668", "id": "P53668", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53668", "id": "P53668", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Limk1", "uniprot_ac": "P53669", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53669", "id": "P53669", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53669", "id": "P53669", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Limk2", "uniprot_ac": "P53670", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53670", "id": "P53670", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53670", "id": "P53670", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "LIMK2", "uniprot_ac": "P53671", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53671", "id": "P53671", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53671", "id": "P53671", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "MAPK12", "uniprot_ac": "P53778", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53778", "id": "P53778", "database": "UniProtKB" } ], "ec_number": "2.7.11.24", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53778", "id": "P53778", "database": "UniProtKB" } ], "ec_number": "2.7.11.24", "activity": "" } ] }, { "gene_name": "MAPK10", "uniprot_ac": "P53779", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53779", "id": "P53779", "database": "UniProtKB" } ], "ec_number": "2.7.11.24", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P53779", "id": "P53779", "database": "UniProtKB" } ], "ec_number": "2.7.11.24", "activity": "" } ] }, { "gene_name": "Dmpk", "uniprot_ac": "P54265", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54265", "id": "P54265", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54265", "id": "P54265", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Prkaa1", "uniprot_ac": "P54645", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54645", "id": "P54645", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54645", "id": "P54645", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "ATP + [tau protein] = ADP + [tau protein] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54645", "id": "P54645", "database": "UniProtKB" } ], "ec_number": "2.7.11.27", "activity": "ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54645", "id": "P54645", "database": "UniProtKB" } ], "ec_number": "2.7.11.31", "activity": "ATP + [hydroxymethylglutaryl-CoA reductase (NADPH)] = ADP + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54645", "id": "P54645", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "PRKAA2", "uniprot_ac": "P54646", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54646", "id": "P54646", "database": "UniProtKB" } ], "ec_number": "2.7.11.27", "activity": "ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54646", "id": "P54646", "database": "UniProtKB" } ], "ec_number": "2.7.11.31", "activity": "ATP + [hydroxymethylglutaryl-CoA reductase (NADPH)] = ADP + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54646", "id": "P54646", "database": "UniProtKB" } ], "ec_number": "2.7.11.31", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54646", "id": "P54646", "database": "UniProtKB" } ], "ec_number": "2.7.11.27", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/P54646", "id": "P54646", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a 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"https://www.uniprot.org/uniprot/Q16816", "id": "Q16816", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "ATP + [tau protein] = ADP + [tau protein] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q16816", "id": "Q16816", "database": "UniProtKB" } ], "ec_number": "2.7.11.19", "activity": "2 ATP + phosphorylase b = 2 ADP + phosphorylase a." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q16816", "id": "Q16816", "database": "UniProtKB" } ], "ec_number": "2.7.11.19", "activity": "" } ] }, { "gene_name": "Myo3b", "uniprot_ac": "Q1EG27", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q1EG27", "id": "Q1EG27", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q1EG27", "id": "Q1EG27", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Map3k13", "uniprot_ac": "Q1HKZ5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q1HKZ5", "id": "Q1HKZ5", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q1HKZ5", "id": "Q1HKZ5", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "" } ] }, { "gene_name": "AAK1", "uniprot_ac": "Q2M2I8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q2M2I8", "id": "Q2M2I8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q2M2I8", "id": "Q2M2I8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Gsk3a", "uniprot_ac": "Q2NL51", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q2NL51", "id": "Q2NL51", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "ATP + [tau protein] = ADP + [tau protein] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q2NL51", "id": "Q2NL51", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q2NL51", "id": "Q2NL51", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." } ] }, { "gene_name": "LRRK1", "uniprot_ac": "Q38SD2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q38SD2", "id": "Q38SD2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q38SD2", "id": "Q38SD2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Cdk12", "uniprot_ac": "Q3MJK5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3MJK5", "id": "Q3MJK5", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3MJK5", "id": "Q3MJK5", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3MJK5", "id": "Q3MJK5", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3MJK5", "id": "Q3MJK5", "database": "UniProtKB" } ], "ec_number": "2.7.11.23", "activity": "" } ] }, { "gene_name": "Lmtk2", "uniprot_ac": "Q3TYD6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3TYD6", "id": "Q3TYD6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3TYD6", "id": "Q3TYD6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Cdkl4", "uniprot_ac": "Q3TZA2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3TZA2", "id": "Q3TZA2", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3TZA2", "id": "Q3TZA2", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "Map3k9", "uniprot_ac": "Q3U1V8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3U1V8", "id": "Q3U1V8", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3U1V8", "id": "Q3U1V8", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "" } ] }, { "gene_name": "Mast3", "uniprot_ac": "Q3U214", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3U214", "id": "Q3U214", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3U214", "id": "Q3U214", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Ulk3", "uniprot_ac": "Q3U3Q1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3U3Q1", "id": "Q3U3Q1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3U3Q1", "id": "Q3U3Q1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Nek10", "uniprot_ac": "Q3UGM2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UGM2", "id": "Q3UGM2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UGM2", "id": "Q3UGM2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Wnk2", "uniprot_ac": "Q3UH66", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UH66", "id": "Q3UH66", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UH66", "id": "Q3UH66", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Lrrk1", "uniprot_ac": "Q3UHC2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UHC2", "id": "Q3UHC2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UHC2", "id": "Q3UHC2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Aak1", "uniprot_ac": "Q3UHJ0", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UHJ0", "id": "Q3UHJ0", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UHJ0", "id": "Q3UHJ0", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Pak6", "uniprot_ac": "Q3ULB5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3ULB5", "id": "Q3ULB5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3ULB5", "id": "Q3ULB5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Cdk10", "uniprot_ac": "Q3UMM4", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UMM4", "id": "Q3UMM4", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UMM4", "id": "Q3UMM4", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "Mapkapk3", "uniprot_ac": "Q3UMW7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UMW7", "id": "Q3UMW7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UMW7", "id": "Q3UMW7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Cdkl5", "uniprot_ac": "Q3UTQ8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UTQ8", "id": "Q3UTQ8", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UTQ8", "id": "Q3UTQ8", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "Cdc42bpa", "uniprot_ac": "Q3UU96", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UU96", "id": "Q3UU96", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UU96", "id": "Q3UU96", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Ksr2", "uniprot_ac": "Q3UVC0", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UVC0", "id": "Q3UVC0", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UVC0", "id": "Q3UVC0", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Ttbk2", "uniprot_ac": "Q3UVR3", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UVR3", "id": "Q3UVR3", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3UVR3", "id": "Q3UVR3", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Hipk4", "uniprot_ac": "Q3V016", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3V016", "id": "Q3V016", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3V016", "id": "Q3V016", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Ulk4", "uniprot_ac": "Q3V129", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3V129", "id": "Q3V129", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3V129", "id": "Q3V129", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Cdk15", "uniprot_ac": "Q3V3A1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3V3A1", "id": "Q3V3A1", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q3V3A1", "id": "Q3V3A1", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "Plk5", "uniprot_ac": "Q4FZD7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4FZD7", "id": "Q4FZD7", "database": "UniProtKB" } ], "ec_number": "2.7.11.21", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4FZD7", "id": "Q4FZD7", "database": "UniProtKB" } ], "ec_number": "2.7.11.21", "activity": "" } ] }, { "gene_name": "Mknk1", "uniprot_ac": "Q4G050", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4G050", "id": "Q4G050", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4G050", "id": "Q4G050", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Cdk20", "uniprot_ac": "Q4KM34", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4KM34", "id": "Q4KM34", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4KM34", "id": "Q4KM34", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "Cdk10", "uniprot_ac": "Q4KM47", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4KM47", "id": "Q4KM47", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4KM47", "id": "Q4KM47", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "Map2k7", "uniprot_ac": "Q4KSH7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4KSH7", "id": "Q4KSH7", "database": "UniProtKB" } ], "ec_number": "2.7.12.2", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4KSH7", "id": "Q4KSH7", "database": "UniProtKB" } ], "ec_number": "2.7.12.2", "activity": "" } ] }, { "gene_name": "Hipk4", "uniprot_ac": "Q4V793", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4V793", "id": "Q4V793", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4V793", "id": "Q4V793", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Dyrk3", "uniprot_ac": "Q4V8A3", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4V8A3", "id": "Q4V8A3", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q4V8A3", "id": "Q4V8A3", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "SBK1", "uniprot_ac": "Q52WX2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q52WX2", "id": "Q52WX2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q52WX2", "id": "Q52WX2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Taok3", "uniprot_ac": "Q53UA7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q53UA7", "id": "Q53UA7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q53UA7", "id": "Q53UA7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "MAP3K19", "uniprot_ac": "Q56UN5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q56UN5", "id": "Q56UN5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q56UN5", "id": "Q56UN5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "TNNI3K", "uniprot_ac": "Q59H18", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q59H18", "id": "Q59H18", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q59H18", "id": "Q59H18", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Prkaa1", "uniprot_ac": "Q5EG47", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5EG47", "id": "Q5EG47", "database": "UniProtKB" } ], "ec_number": "2.7.11.27", "activity": "ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5EG47", "id": "Q5EG47", "database": "UniProtKB" } ], "ec_number": "2.7.11.31", "activity": "ATP + [hydroxymethylglutaryl-CoA reductase (NADPH)] = ADP + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5EG47", "id": "Q5EG47", "database": "UniProtKB" } ], "ec_number": "2.7.11.27", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5EG47", "id": "Q5EG47", "database": "UniProtKB" } ], "ec_number": "2.7.11.31", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5EG47", "id": "Q5EG47", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5EG47", "id": "Q5EG47", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "ATP + [tau protein] = ADP + [tau protein] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5EG47", "id": "Q5EG47", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Taok1", "uniprot_ac": "Q5F2E8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5F2E8", "id": "Q5F2E8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5F2E8", "id": "Q5F2E8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Tnni3k", "uniprot_ac": "Q5GIG6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5GIG6", "id": "Q5GIG6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5GIG6", "id": "Q5GIG6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Riok2", "uniprot_ac": "Q5I0I1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5I0I1", "id": "Q5I0I1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": 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"activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5RJI5", "id": "Q5RJI5", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "" } ] }, { "gene_name": "Prpf4b", "uniprot_ac": "Q5RKH1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5RKH1", "id": "Q5RKH1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5RKH1", "id": "Q5RKH1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Lrrk2", "uniprot_ac": "Q5S006", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5S006", "id": "Q5S006", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5S006", "id": "Q5S006", "database": "UniProtKB" } ], "ec_number": "3.6.5.-", 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phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5SUV5", "id": "Q5SUV5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Rskr", "uniprot_ac": "Q5SYL1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5SYL1", "id": "Q5SYL1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5SYL1", "id": "Q5SYL1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "MAP3K21", "uniprot_ac": "Q5TCX8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5TCX8", "id": "Q5TCX8", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5TCX8", "id": "Q5TCX8", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "" } ] }, { "gene_name": "TTBK1", "uniprot_ac": "Q5TCY1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5TCY1", "id": "Q5TCY1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5TCY1", "id": "Q5TCY1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Mknk2", "uniprot_ac": "Q5U2N4", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5U2N4", "id": "Q5U2N4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5U2N4", "id": "Q5U2N4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Tnk2", "uniprot_ac": "Q5U2X5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5U2X5", "id": "Q5U2X5", 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"database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Dyrk2", "uniprot_ac": "Q5U4C9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5U4C9", "id": "Q5U4C9", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5U4C9", "id": "Q5U4C9", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "OBSCN", "uniprot_ac": "Q5VST9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5VST9", "id": "Q5VST9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q5VST9", "id": "Q5VST9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { 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"https://www.uniprot.org/uniprot/Q6VAB6", "id": "Q6VAB6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6VAB6", "id": "Q6VAB6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Dstyk", "uniprot_ac": "Q6XUX1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6XUX1", "id": "Q6XUX1", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6XUX1", "id": "Q6XUX1", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "Dstyk", "uniprot_ac": "Q6XUX2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6XUX2", "id": "Q6XUX2", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6XUX2", "id": "Q6XUX2", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "DSTYK", "uniprot_ac": "Q6XUX3", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6XUX3", "id": "Q6XUX3", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6XUX3", "id": "Q6XUX3", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "AATK", "uniprot_ac": "Q6ZMQ8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6ZMQ8", "id": "Q6ZMQ8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6ZMQ8", "id": "Q6ZMQ8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "MAP3K15", "uniprot_ac": "Q6ZN16", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6ZN16", "id": "Q6ZN16", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6ZN16", "id": "Q6ZN16", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "" } ] }, { "gene_name": "Taok2", "uniprot_ac": "Q6ZQ29", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6ZQ29", "id": "Q6ZQ29", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6ZQ29", "id": "Q6ZQ29", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "NEK10", "uniprot_ac": "Q6ZWH5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6ZWH5", "id": "Q6ZWH5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q6ZWH5", "id": "Q6ZWH5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "ERN2", "uniprot_ac": "Q76MJ5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q76MJ5", "id": "Q76MJ5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q76MJ5", "id": "Q76MJ5", "database": "UniProtKB" } ], "ec_number": "3.1.26.-", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q76MJ5", "id": "Q76MJ5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "MARK2", "uniprot_ac": "Q7KZI7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7KZI7", "id": "Q7KZI7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7KZI7", "id": "Q7KZI7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7KZI7", "id": "Q7KZI7", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "ATP + [tau protein] = ADP + [tau protein] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7KZI7", "id": "Q7KZI7", "database": "UniProtKB" } ], "ec_number": "2.7.11.26", "activity": "" } ] }, { "gene_name": "TAOK1", "uniprot_ac": "Q7L7X3", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7L7X3", "id": "Q7L7X3", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7L7X3", "id": "Q7L7X3", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Camk1g", "uniprot_ac": "Q7TNJ7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7TNJ7", "id": "Q7TNJ7", "database": "UniProtKB" } ], "ec_number": "2.7.11.17", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7TNJ7", "id": "Q7TNJ7", "database": "UniProtKB" } ], "ec_number": "2.7.11.17", "activity": "" } ] }, { "gene_name": "Stk40", "uniprot_ac": "Q7TNL3", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7TNL3", "id": "Q7TNL3", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7TNL3", "id": "Q7TNL3", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Stk40", "uniprot_ac": "Q7TNL4", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7TNL4", "id": "Q7TNL4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7TNL4", "id": "Q7TNL4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Wnk4", "uniprot_ac": "Q7TPK6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7TPK6", "id": "Q7TPK6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q7TPK6", "id": "Q7TPK6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Rps6ka6", 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} ] }, { "gene_name": "Taf1", "uniprot_ac": "Q80UV9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80UV9", "id": "Q80UV9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80UV9", "id": "Q80UV9", "database": "UniProtKB" } ], "ec_number": "2.3.1.48", "activity": "Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80UV9", "id": "Q80UV9", "database": "UniProtKB" } ], "ec_number": "2.3.1.48", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80UV9", "id": "Q80UV9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Cdc42bpg", "uniprot_ac": "Q80UW5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80UW5", "id": "Q80UW5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80UW5", "id": "Q80UW5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Vrk1", "uniprot_ac": "Q80X41", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80X41", "id": "Q80X41", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80X41", "id": "Q80X41", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Map3k11", "uniprot_ac": "Q80XI6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80XI6", "id": "Q80XI6", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80XI6", "id": "Q80XI6", "database": "UniProtKB" } ], "ec_number": "2.7.11.25", "activity": "" } ] }, { "gene_name": "Wnk3", "uniprot_ac": "Q80XP9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80XP9", "id": "Q80XP9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80XP9", "id": "Q80XP9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Mapk15", "uniprot_ac": "Q80Y86", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80Y86", "id": "Q80Y86", "database": "UniProtKB" } ], "ec_number": "2.7.11.24", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80Y86", "id": "Q80Y86", "database": "UniProtKB" } ], "ec_number": "2.7.11.24", "activity": "" } ] }, { "gene_name": "Aatk", "uniprot_ac": "Q80YE4", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80YE4", "id": "Q80YE4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80YE4", "id": "Q80YE4", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Dapk1", "uniprot_ac": "Q80YE7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80YE7", "id": "Q80YE7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80YE7", "id": "Q80YE7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Cdk3", "uniprot_ac": "Q80YP0", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80YP0", "id": "Q80YP0", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80YP0", "id": "Q80YP0", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "Stk35", "uniprot_ac": "Q80ZW0", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q80ZW0", "id": "Q80ZW0", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." } ] }, { "gene_name": "Mast1", "uniprot_ac": "Q810W7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q810W7", "id": "Q810W7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q810W7", "id": "Q810W7", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Mast4", "uniprot_ac": "Q811L6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q811L6", "id": "Q811L6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q811L6", "id": "Q811L6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "NEK8", "uniprot_ac": "Q86SG6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86SG6", "id": "Q86SG6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86SG6", "id": "Q86SG6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "ALPK2", "uniprot_ac": "Q86TB3", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86TB3", "id": "Q86TB3", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86TB3", "id": "Q86TB3", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "TLK2", "uniprot_ac": "Q86UE8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86UE8", "id": "Q86UE8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86UE8", "id": "Q86UE8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "STK32C", "uniprot_ac": "Q86UX6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86UX6", "id": "Q86UX6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86UX6", "id": "Q86UX6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "PIM3", "uniprot_ac": "Q86V86", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86V86", "id": "Q86V86", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86V86", "id": "Q86V86", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "VRK2", "uniprot_ac": "Q86Y07", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86Y07", "id": "Q86Y07", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86Y07", "id": "Q86Y07", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "MYLK4", "uniprot_ac": "Q86YV6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86YV6", "id": "Q86YV6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86YV6", "id": "Q86YV6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "HIPK1", "uniprot_ac": "Q86Z02", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86Z02", "id": "Q86Z02", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q86Z02", "id": "Q86Z02", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Stk17b", "uniprot_ac": "Q8BG48", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BG48", "id": "Q8BG48", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BG48", "id": "Q8BG48", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Stk32a", "uniprot_ac": "Q8BGW6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BGW6", "id": "Q8BGW6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BGW6", "id": "Q8BGW6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Nim1k", "uniprot_ac": "Q8BHI9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BHI9", "id": "Q8BHI9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BHI9", "id": "Q8BHI9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Dyrk4", "uniprot_ac": "Q8BI55", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BI55", "id": "Q8BI55", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "ATP + L-seryl/L-threonyl/L-tyrosyl-[protein] = ADP + O-phospho-L-seryl/O-phospho-L-threonyl/O-phospho-L-tyrosyl-[protein]." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BI55", "id": "Q8BI55", "database": "UniProtKB" } ], "ec_number": "2.7.12.1", "activity": "" } ] }, { "gene_name": "Csnk1a1", "uniprot_ac": "Q8BK63", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BK63", "id": "Q8BK63", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BK63", "id": "Q8BK63", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Smg1", "uniprot_ac": "Q8BKX6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BKX6", "id": "Q8BKX6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BKX6", "id": "Q8BKX6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Cdkl3", "uniprot_ac": "Q8BLF2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BLF2", "id": "Q8BLF2", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BLF2", "id": "Q8BLF2", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "Rps6kc1", "uniprot_ac": "Q8BLK9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BLK9", "id": "Q8BLK9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BLK9", "id": "Q8BLK9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Vrk2", "uniprot_ac": "Q8BN21", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BN21", "id": "Q8BN21", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BN21", "id": "Q8BN21", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Map4k5", "uniprot_ac": "Q8BPM2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BPM2", "id": "Q8BPM2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BPM2", "id": "Q8BPM2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Prkaa2", "uniprot_ac": "Q8BRK8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BRK8", "id": "Q8BRK8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BRK8", "id": "Q8BRK8", "database": "UniProtKB" } ], "ec_number": "2.7.11.27", "activity": "ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BRK8", "id": "Q8BRK8", "database": "UniProtKB" } ], "ec_number": "2.7.11.31", "activity": "ATP + [hydroxymethylglutaryl-CoA reductase (NADPH)] = ADP + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BRK8", "id": "Q8BRK8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Rps6kb1", "uniprot_ac": "Q8BSK8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BSK8", "id": "Q8BSK8", "database": 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"uniprot_ac": "Q8BWD8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BWD8", "id": "Q8BWD8", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BWD8", "id": "Q8BWD8", "database": "UniProtKB" } ], "ec_number": "2.7.11.22", "activity": "" } ] }, { "gene_name": "Dclk3", "uniprot_ac": "Q8BWQ5", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BWQ5", "id": "Q8BWQ5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BWQ5", "id": "Q8BWQ5", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Pkn2", "uniprot_ac": "Q8BWW9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BWW9", "id": "Q8BWW9", "database": "UniProtKB" } ], "ec_number": "2.7.11.13", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BWW9", "id": "Q8BWW9", "database": "UniProtKB" } ], "ec_number": "2.7.11.13", "activity": "" } ] }, { "gene_name": "Taok3", "uniprot_ac": "Q8BYC6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BYC6", "id": "Q8BYC6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BYC6", "id": "Q8BYC6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Lats1", "uniprot_ac": "Q8BYR2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BYR2", "id": "Q8BYR2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BYR2", "id": "Q8BYR2", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Prkd2", "uniprot_ac": "Q8BZ03", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BZ03", "id": "Q8BZ03", "database": "UniProtKB" } ], "ec_number": "2.7.11.13", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BZ03", "id": "Q8BZ03", "database": "UniProtKB" } ], "ec_number": "2.7.11.13", "activity": "" } ] }, { "gene_name": "Ankk1", "uniprot_ac": "Q8BZ25", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BZ25", "id": "Q8BZ25", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q8BZ25", "id": "Q8BZ25", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Nuak2", "uniprot_ac": "Q8BZN4", "activity": [ { "evidence": [ { "url": 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"" } ] }, { "gene_name": "TAOK3", "uniprot_ac": "Q9H2K8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9H2K8", "id": "Q9H2K8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9H2K8", "id": "Q9H2K8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "HIPK2", "uniprot_ac": "Q9H2X6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9H2X6", "id": "Q9H2X6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9H2X6", "id": "Q9H2X6", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "HIPK3", "uniprot_ac": "Q9H422", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9H422", "id": "Q9H422", "database": 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} ] }, { "gene_name": "SGK2", "uniprot_ac": "Q9HBY8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9HBY8", "id": "Q9HBY8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9HBY8", "id": "Q9HBY8", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "NEK6", "uniprot_ac": "Q9HC98", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9HC98", "id": "Q9HC98", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9HC98", "id": "Q9HC98", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "CSNK1G1", "uniprot_ac": "Q9HCP0", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9HCP0", "id": "Q9HCP0", "database": 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"Q9Z2R9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9Z2R9", "id": "Q9Z2R9", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Stk25", "uniprot_ac": "Q9Z2W1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9Z2W1", "id": "Q9Z2W1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9Z2W1", "id": "Q9Z2W1", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] }, { "gene_name": "Sbk1", "uniprot_ac": "Q9Z335", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9Z335", "id": "Q9Z335", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "ATP + a protein = ADP + a phosphoprotein." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9Z335", "id": "Q9Z335", "database": "UniProtKB" } ], "ec_number": "2.7.11.1", "activity": "" } ] } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/15185077", "type": "PubMed", "id": "15185077" } ], "title": "Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.", "journal": "Dev. Genes Evol.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954603.3", "id": "NP_954603.3", "database": "RefSeq" } ], "authors": "Russell M.W., Borisov A.B., Raeker M.O., Sutter S.B.", "date": "2004" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/15289607", "type": "PubMed", "id": "15289607" } ], "title": "The mouse kinome: discovery and comparative genomics of all mouse protein kinases.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "authors": "Caenepeel S., Hunter T., Manning G., Sudarsanam S., Charydczak G.", "date": "2004" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/21183079", "type": "PubMed", "id": "21183079" } ], "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" }, { "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AAJ9", "id": "A2AAJ9", "database": "iPTMnet" } ], "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "date": "2010" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/23392350", "type": "PubMed", "id": "23392350" } ], "title": "The kinase domains of obscurin interact with intercellular adhesion proteins.", "journal": "FASEB J.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "authors": "Kontrogianni-Konstantopoulos A., Hu L.Y.", "date": "2013" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/28826662", "type": "PubMed", "id": "28826662" } ], "title": "Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.", "journal": "J. Mol. Cell. Cardiol.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954603.3", "id": "NP_954603.3", "database": "RefSeq" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164983.2", "id": "NP_001164983.2", "database": "RefSeq" } ], "authors": "Kontrogianni-Konstantopoulos A., Wright N.T., Hecker P.A., King B., Ackermann M.A., Berndsen C.E., Bobbili P.J., Lieberman N.A.P., Rudloff M.", "date": "2017" } ], "uniprot_ac": "A2AAJ9", "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AAJ9", "type": "synonym", "resource": "RefSeq", "name": "BC046431; Gm878; UNC89" }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "type": "synonym", "resource": "UniProtKB", "name": "Gm878" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AAJ9", "type": "synonym", "resource": "RefSeq", "name": "Obscn" }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "type": "recommended", "resource": "UniProtKB", "name": "Obscn" } ], "reactions": [ { "output_participant_list": [], "evidence": [ { "url": "https://www.rhea-db.org/rhea/17989", "id": "17989", "database": "Rhea" } ], "name": "", "cellular_location": "", "equation": "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]", "input_participant_list": [], "enzyme_list": [ "P36506-1", "D3Z8E0-1", "F1LYL8-1", "D3ZQ51-1", "P68403-1", "D4ACL8-1", "P49185-1", "P42346-1", "P09215-1", "Q63484-1", "O08679-1", "O08678-1", "A0A0G2K366-1", "A0A0G2JU41-1", "A0A0G2K2H4-1", "Q4V8A3-1", "A0A0G2K5V8-1", "D3ZHL6-1", "A0A0G2K2Y2-1", "Q62763-1", "Q62761-1", "E9PTG8-1", "F7EN76-1", "M0RD40-1", "A0A0G2K212-1", "D4A648-1", "D3Z837-1", "A0A0G2K8N1-1", "A0A0G2JVL3-1", "Q924I2-1", "D4AAT5-1", "F1LNJ1-1", "O08874-1", "M0R3L1-1", "F1M7G0-1", "D3ZZH6-1", "D4A355-1", "Q7TT49-1", "O54748-1", "D3ZFL3-1", "D3ZXB1-1", "P08413-1", "Q9JIH7-1", "Q09137-1", "P0C1X8-1", "Q63470-1", "P0C8E4-1", "D4A6T9-1", "Q8VHF0-1", "P05696-1", 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"Q9QZL0-1", "Q5U452-1" ], "id": "17989", "summary": "" }, { "output_participant_list": [], "evidence": [ { "url": "https://www.rhea-db.org/rhea/46608", "id": "46608", "database": "Rhea" } ], "name": "", "cellular_location": "", "equation": "ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]", "input_participant_list": [], "enzyme_list": [ "P36506-1", "D3Z8E0-1", "F1LYL8-1", "D3ZHL6-1", "D3ZQ51-1", "P68403-1", "F7EN76-1", "D4ACL8-1", "Q924I2-1", "P49185-1", "P42346-1", "P09215-1", "Q63484-1", "O08679-1", "O08678-1", "D3ZXB1-1", "A0A0G2K366-1", "A0A0G2JU41-1", "A0A0G2K2H4-1", "Q4V8A3-1", "A0A0G2K5V8-1", "A0A0G2K2Y2-1", "Q62763-1", "Q62761-1", "E9PTG8-1", "M0RD40-1", "A0A0G2K212-1", "D4A648-1", "D3Z837-1", "A0A0G2K8N1-1", "A0A0G2JVL3-1", "D4AAT5-1", "F1LNJ1-1", "O08874-1", "M0R3L1-1", "F1M7G0-1", "D3ZZH6-1", "D4A355-1", "Q7TT49-1", "D3ZTD1-1", "D4A7K4-1", "O54748-1", "D3ZFL3-1", "P08413-1", "Q9JIH7-1", "Q09137-1", "P0C1X8-1", "Q63470-1", "P0C8E4-1", "D4A6T9-1", 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"Q13315-1", "P06493-1", "P50750-1", "Q9NYL2-1", "P46734-1", "Q8NG66-1", "Q96S44-1", "Q13464-1", "P57059-1", "Q9Y2K2-5", "P49842-1", "Q6IQ55-1", "Q9BXA6-1", "O43293-1", "Q07912-1", "P11274-1", "P24941-1", "Q00536-1", "P11802-1", "Q8IXL6-1", "Q9UPZ9-1", "Q8IU85-1", "P05771-1", "Q8IVT5-1", "Q05513-1", "O43318-1", "P20794-1", "P45983-1", "Q5VT25-1", "Q6DT37-1", "Q9BUB5-1", "P53350-1", "P11309-1", "Q9NRH2-1", "Q9UKI8-1", "Q9UHD2-1", "Q86UE8-1", "Q9BYP7-1", "Q99986-1", "Q8TF76-1", "P49674-1", "Q5S007-1", "Q99683-1", "P53671-1", "Q9Y572-1", "P78362-1", "Q2M2I8-1", "O95835-1", "P31749-1", "P68400-1", "P78527-1", "Q13546-1", "P33981-1", "O75385-1", "Q7TT50-1", "Q5SYL1-1", "P31750-1", "O88445-1", "Q5RJI5-1", "Q9Z1S0-1", "O08901-1", "P79621-1", "P54265-1", "Q6XUX1-1", "Q03963-1", "Q5U4C9-1", "Q8BI55-1", "Q9QZ05-1", "Q9Z2B5-1", "Q5MJS3-1", "Q9WV60-1", "Q923T9-1", "P68404-1", "Q91YA2-1", "A2CG49-1", "P68181-1", "Q6PHZ2-1", "Q7TPS0-1", "Q8BK63-1", "Q8BTH8-1", "Q8C4X2-1", "Q91YS8-1", "Q62101-1", "Q8K1Y2-1", "Q9Z2B9-1", "O35099-1", "Q8VDG6-1", "Q03141-1", "O08605-1", "Q3UMW7-1", "Q61532-1", "Q61846-1", "Q9WVS4-1", "Q9WVS8-1", "P63085-1", "Q6P5G0-1", "P00536-1", "P31938-1", "O09110-1", "Q9WVS7-1", "Q1EG27-1", "Q80UW5-1", "Q8K3H5-1", "Q5SUV5-1", "Q8BHI9-1", "P70268-1", "Q61136-1", "Q922R0-1", "Q99PW4-1", "P70336-1", "Q8R2S1-1", "P0C5K0-1", "P0C5K1-1", "Q8C0X8-1", "Q8VDU5-1", "Q9QYZ4-1", "C0HKC9-1", "Q62407-1", "Q8C0V7-1", "O54988-1", "O70551-1", "Q9Z0G2-1", "P83510-1", "Q9JJ78-1", "Q8C0V0-1", "Q3UVR3-1", "Q9D2E1-1", "Q6PCN3-1", "Q80UE6-1", "Q91Z96-1", "Q9JKV2-1", "Q60592-1", "Q9ES70-1", "Q9Z2A0-1", "Q60670-1", "Q62073-1", "Q66L42-1", "Q91Y86-1", "Q3UU96-1", "P28867-1", "P83741-1", "Q811L6-1", "Q8CFH6-1", "P70218-1", "P0C605-1", "Q61831-1", "Q05512-1", "P97477-1", "Q62388-1", "Q9DC28-1", "P53668-1", "P97820-1", "Q9WTU6-1", "O54949-1", "P97313-1", "Q9Z1M4-1", "P18653-1", "P18654-1", "Q63844-1", "Q8BPM2-1", "Q9Z1B7-1", "Q99JP0-1", "Q3UH66-1", "Q61214-1", "P28652-1", "Q9JI10-1", "Q3U214-1", "Q6P4S6-1", "A2AAJ9-1", "Q9WTR2-1", "Q03147-1", "Q02111-1", "P04627-1", "E9Q3S4-1", "P49615-1", "Q04899-1", "Q3TZA2-1", "Q3V3A1-1", "P11440-1", "Q8BLF2-1", "Q8R3L8-1", "O54833-1", "Q80TR8-1", "Q9Z2E3-1", "Q9EQY0-1", "Q2NL51-1", "Q9ERH7-1", "Q9Z0R0-1", "Q9QZR5-1", "O88904-1", "Q3V016-1", "Q8R4K2-1", "Q8BVP5-1", "Q8BW96-1", "Q9QYK9-1", "P16054-1", "P08414-1", "Q02956-1", "Q8C078-1", "Q8VBY2-1", "O54992-1", "Q04859-1", "Q3U1V8-1", "Q3UHC2-1", "Q60700-1", "Q80XI6-1", "Q80YE4-1", "Q9R1L5-1", "Q3TYD6-1", "A2AQW0-1", "O08648-1", "P53349-1", "Q07174-1", "Q1HKZ5-1", "Q5XJV6-1", "Q61083-1", "P47809-1", "P70236-1", "Q8C0Q4-1", "Q91ZR4-1", "Q9ES74-1", "Q3UGM2-1", "Q7TSC3-1", "Q8K1R7-1", "Q9Z1J2-1", "Q9R0A5-1", "Q641K5-1", "Q9R0G8-1", "Q8C015-1", "Q8BZN4-1", "Q8CIN4-1", "Q3ULB5-1", "Q61036-1", "Q6P9R2-1", "Q8BTW9-1", "P42337-1", "Q8VD65-1", "Q99N57-1", "Q8C050-1", "Q62070-1", "Q5EG47-1", "Q8BRK8-1", "Q924C5-1", "Q60823-1", "Q9CXB8-1", "Q9WUA6-1", "P24788-1", "Q9Z0H0-1", "O35495-1", "Q14AX6-1", "Q3UMM4-1", "Q64261-1", "Q8BWD8-1", "Q3UTQ8-1", "Q8CEQ0-1", "Q04735-1", "Q8K0D0-1", "O70589-1", "Q80YE7-1", "Q8BWQ5-1", "Q8VDF3-1", "Q9JLM8-1", "Q6PGN3-1", "Q62406-1", "Q91VB2-1", "Q9ESL4-1", "P49138-1", "Q61084-1", "Q9JM52-1", "Q8CDB0-1", "Q8CEE6-1", "Q07832-1", "P58750-1", "Q64702-1", "Q9JHG7-1", "P06803-1", "P53351-1", "Q60806-1", "Q8K045-1", "P07934-1", "Q9ESG9-1", "Q922Q2-1", "Q8QZX0-1", "A2KF29-1", "Q8BKX6-1", "Q8C0N0-1", "A0AUV4-1", "C0HKC8-1", "Q9ERE3-1", "Q9QZS5-1", "Q9WVC6-1", "O88697-1", "Q80ZW0-1", "Q9JJX8-1", "Q9QYZ3-1", "O55098-1", "Q8BGW6-1", "Q924X7-1", "Q99KH8-1", "Q99MW1-1", "Q9WTK7-1", "Q9Z2W1-1", "Q69ZM6-1", "Q7TNL3-1", "Q7TSE6-1", "Q8BG48-1", "Q8QZV4-1", "Q9Z1W9-1", "Q91VJ4-1", "Q99JT2-1", "Q9JI11-1", "Q0KL02-1", "Q3U3Q1-1", "Q3V129-1", "Q8C1R0-1", "Q9QY01-1", "Q5GIG6-1", "Q8CIR4-1", "Q923J1-1", "O54967-1", "Q8BZ25-1", "O70126-1", "Q9JKK8-1", "Q69Z98-1", "P28028-1", "Q69ZA1-1", "P30285-1", "Q80YP0-1", "Q9JHU3-1", "Q9QUK0-1", "P22518-1", "O35491-1", "O35492-1", "O35493-1", "Q9Z265-1", "Q99KY4-1", "Q8C0P0-1", "O88866-1", "O55222-1", "Q61410-1", "P05132-1", "P20444-1", "Q62074-1", "Q9WUT3-1", "P23298-1", "P63318-1", "Q61097-1", "Q8BSK8-1", "Q8BLK9-1", "Q9WUL6-1", "Q7TSJ6-1", "Q5S006-1", "Q61161-1", "Q8VHJ5-1", "O08911-1", "Q80Y86-1", "Q9WUI1-1", "O35942-1", "O88643-1", "Q8QZR7-1", "Q8BWW9-1", "P58801-1", "Q9DBU3-1", "Q9ERK0-1", "Q9CQS5-1", "Q9QYZ6-1", "Q5F2E8-1", "Q6ZQ29-1", "Q8BYC6-1", "Q80UV9-1", "O70146-1", "Q8VCT9-1", "O55047-1", "A2ASS6-1", "P97343-1", "P49025-1", "Q4FZD7-1", "Q9Z188-1", "Q91ZB0-1", "Q6PAJ1-1", "P97377-1", "Q922Y0-1", "Q8BZ03-1", "Q3UVC0-1", "Q8CIP4-1", "P47811-1", "Q63932-1", "Q8CE90-1", "Q9JLN9-1", "Q9JHN8-1", "Q61241-1", "Q9D411-1", "O70405-1", "O54863-1", "Q925K9-1", "Q8BN21-1", "Q80X41-1", "Q80XP9-1", "Q99J95-1", "O54784-1", "Q8K4B2-1", "P11798-1", "O54785-1", "P51954-1", "Q99MQ3-1", "P70335-1", "O35280-1", "Q60737-1", "Q9Z2R9-1", "Q9JMK2-1", "Q60855-1", "O54781-1", "O88351-1", "Q9WUN2-1", "P35761-1", "Q3UHJ0-1", "Q8BYR2-1", "Q9QZL0-1", "Q5U452-1" ], "id": "46608", "summary": "" } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9#A0A1W2P6H1-1", "isoform_ac": "A0A1W2P6H1-1", "locus": { "end_pos": 59012659, "strand": "+", "start_pos": 59136375, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000219084", "id": "ENSMUST00000219084", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000151217", "id": "ENSMUSP00000151217", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A1W2P6H1-1|A0A1W2P6H1_MOUSE Computationally mapped isoform of Non-specific serine/threonine protein kinase OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=2 CANONICAL=A2AAJ9-1", "length": 6661, "sequence": "MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFKKRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCVSAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKFVANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQDITDGYRDWGPAGPQKHMCKCAGAKIARYLGSSCYRFLQYDKGVWHWLEAALDTRQGKGTSSCSLHEKPKLVFAKGQQAHSEVKAEAGNSATLSCEVTQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEGVHTSARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPVDVRWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRFRESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRGLPAKFIEDLRSQEATEGATAILRCELSKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSSLPTKFTEGLRNEEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPKFTEGLKKEEATEGTMVTLRCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCELQIRDLAVEDAGEYLCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKAPQVVFQQPLQNLQAEEGSMASLRCELSVPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADGCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTVRVPEVTVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRGWRLEVLEPPHDASVKAGMQVRFTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGEVTFAARDAVASARLSVLALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAPETRQAVVGEDICLELEVAADGGEVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEYRCGPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDSRVQHLRQEAEETAPDLSEGYSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGGPGISPLASKHEAQVTTSVKPQKQQEPVVPTCPPPGDLSAADLMDPSLDKAAVKIQAAFKGYKVRKEMKQQEGPVFSRTFGDTEAQVGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYTCQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEELFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGIGVEISLGEQGPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMSESAGFADLVGQSKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQVPGGDSDEETKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKLSPEWGPTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLERSPRVPAAVASQKTVIFRNVQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGRVQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEVTEQETKVPKKTVIIEETITTVVKSPRGRRQSPGKSPSRSPSRRSASPRRPGLLAPERLYPPGTSPSRRLEVEQGRKAPVPALYVTEAEVHAPASQSQPKWLEVEETIEVRVKKTGSRGASPVREMTSRGEGILFTLPGGIPGRDPNANNSNNKSVYQEARTWGPAVVHVGEPFIFQVDSVGNVDWVAASPEPEQVRASQKEENTERQEGCSDGDENTFLMEEPQDTDSLQGRDPKILTHNGRVLTLADLEDYVPQEGETFGCGDSTPSTPDEPPCEVSVLQREISEPTVGQPVLLNVGRPPGTGATPSFFRPGSQVHSPESVSFLLREAWSGPVSAAPWTSSFHTHVQSSVDGSHGSFKTEVSTQTVSFGAVGETVTLHIDPDGGEAPGPSQG" } }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9#A0A571BEB2-1", "isoform_ac": "A0A571BEB2-1", "locus": { "end_pos": 59043882, "strand": "+", "start_pos": 59049500, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000238202", "id": "ENSMUST00000238202", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000158662", "id": "ENSMUSP00000158662", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A571BEB2-1|OBSCN_MOUSE Computationally mapped isoform of Obscurin OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=1 CANONICAL=A2AAJ9-1", "length": 296, "sequence": "VTLEDAGTITLQVGSCSSEAQLKVTEAALCLVRGLQNVDVFAGEVATFSCEVSRAGGPEARWWLDGTLLQNSPESAITVQEGIVHSLTLSGLGVADSGTITFRTGPLVSTAKLLVKDPTVEVVSAMQDLVVEEGGSAELLCQYSRPVQATWKMNEREVCADGHRVIIEQDWTVARLTLRPALPCDSGIYSCEAAGTRVVALLQVQAKNTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVR" } }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9#A2AAJ9-1", "isoform_ac": "A2AAJ9-1", "locus": { "end_pos": 58994335, "strand": "+", "start_pos": 59136375, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000238536", "id": "ENSMUST00000238536", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000158795", "id": "ENSMUSP00000158795", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AAJ9-1|OBSCN_MOUSE Isoform 1 of Obscurin OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=3 CANONICAL=A2AAJ9-1", "length": 8886, "sequence": "MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFKKRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCVSAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKFVANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQDITDGYRDWGPAGPQKHMCKCAGAKIARYLGSSCYRFLQYDKGVWHWLEAALDTRQGKGTSSCSLHEKPKLVFAKGQQAHSEVKAEAGNSATLSCEVTQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLMFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVADTRLMFAKEQQARTEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEGVHTSARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPVDVRWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRFRESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRALPAKFKDSLKNEEATEGTTATLSCELSKAAPVTWKKGPKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQEKTSATLTVRGLPAKFIEDLRSQEATEGATAILRCELSKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSSLPTKFTEGLRNEEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPSRFIEDLRSQEATEGTMATLRCQMSKTAPVEWKKGSETLRDGGRYSLRQDGPVCELQICDLAVEDAGEYSCVCGQEKTSATLSIKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKKEEATEGTMVTLRCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCELQIRDLAVEDAGEYLCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKALPPRFIEDLRSQEAREGTVATLRCRMSKAAPVEWRKGSETLKDGDRYSLRQEGNLCELQIRDLAVEDTEEYSCVCGQEKTSATLSVKALPAKFIEDLRSQEAPESSTVTLRCKLSKKASVVWKKGSETLRNGARYSLRQDGAVCELEIRDLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQNLQAEEGSMASLRCELSVPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADGCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTVRVPEVTVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRGWRLEVLEPPHDASVKAGMQVRFTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGEVTFAARDAVASARLSVLALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAPAPETRQAVVGEDICLELEVAADGGEVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEYRCGPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDSRVQHLRQEAEETAPDLSEGYSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGGPGISPLASKHEAQVTTSVKPQKQQEPVVPTCPPPGDLSAADLMDPSLDKAAVKIQAAFKGYKVRKEMKQQEGPVFSRTFGDTEAQVGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYTCQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEELFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGIGVEISLGEQGPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMSESAGFADLVGQSKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQVPGGDSDEETKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKLSPEWGPTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLERSPRVPAAVASQKTVIFRNVQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGRVQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEDTSVEGSAHSAQDGADQQAASVLWRLLGSEALGPSPGDLPNTRQSEPPAFEEAASQIPGAASGTPEVSQPGTHKGLEQETTSSGSQGWTVPIRVEGTAWPGAGTGQLLLDVHSQVIMETTQRTYVCQAPDTGVTRAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELLVHGGDKLDAENQVYRRKLHSFYDVQEEIGRGVFGFVKRVQHKGNKMFCAAKFIPLRSKTRAQAYQERDILATLGHPLVTGLLDQFETRKTLILILELCSSEELLDRLFKKGVVTEAEVKVYIQQLVEGLHYLHSHGILHLDIKPPNILMVHPAREDIKICDFGFAQKITPSEPQYSKYGSPEFVSPEIIEQNPVSEGSDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPTAAHLSEDAKDFIKATLQRTPRARPSTSQCLAHPWFLKSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSILVMRSIPELLQGPPDSPSLGVARHLRGEASGASSSSSSSDNELAPFARAKSLPPSPVTHSPLLHPRGFLRPSASLPEETEASMPTADAAVPASPQSAGPPASPGCVPRHSVISSLFYQQAGEGAERGNKTSGAKRHPARRRHLLKGGYIARALPGLREPLMEYSLLEEEAAREEQASLMTKTPSFETALRLPSSSVREVPGRSHSLDNPPVTTGPSPEACKEQLLFPPSTGLTHETTAKDRGHKEGFLQESVPFPPMSGDSRPGKQEGSSQDSCRGKPASSCHSELGSGSQEGCGPPSSQSLGSLPPQSLKKELSTSCGPLFSEQPQAAPFPTQVSPLLGSEKEPQDGSLSEGPVPVPSSSPGSASQVDASLDTEGLSEAGDTCDFTPPPQRPQEQATTRKFSLESRGGYAGVAGYGTFAFGGDAGGMLGQGPLWARMAWAVSQSSEEQDEAATESPQPLESLGPIAEASGVPLRTSPSLTPWEEVEQVSLVQIRDLSGDAEAADTISLDISEVDPAYLNLSDLYDIKYLPFEFMIFRRVPKPIEQPESPGSETEAGQGLADFLEEAAWPWPGELGLRAGLEITEEPEEPGDLEALLGEAAVGRKRKWSPSRGLFQFPGRCLSGEEPVELGLRQRVKASMAHISRILKGRPEGPEREGPPRKKAGLASFRLSGLKGRDQELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKPVESCGPVTYIVQCCIEGGSWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPYSSPSEQVLLGGPNHLASEEESSRGRPAQLLPSTKTFAFQMQIRRGRFSVVRQCREKASGRALAAKIVPYQPEDKTAVLREYEALKRLHHPHLAQLHAAYLSPRHLVLILELCSGPELLPSLAERESYSESDVKDYLWQMLSATQYLHAQHILHLDLRSENMMVTEYNLLKVIDLGNAQSLDQEKVPAPENFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSGEYPESSEGTRDLQKGLRKGLIRLSRCYAGLSGGAVAFLQSSLCAQPWGRPCASTCLQCGWLTEEGPTGSRPTPVTFPTVRLRAFVREREKRRALLYKKHNLAQVR" } }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9#A2AAJ9-2", "isoform_ac": "A2AAJ9-2", "locus": {}, "sequence": { "header": "sp|A2AAJ9-2|OBSCN_MOUSE Isoform 2 of Obscurin OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=3 CANONICAL=A2AAJ9-1", "length": 345, "sequence": "MENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEERRPSPP" } }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9#A2AAJ9-3", "isoform_ac": "A2AAJ9-3", "locus": {}, "sequence": { "header": "sp|A2AAJ9-3|OBSCN_MOUSE Isoform 3 of Obscurin OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=3 CANONICAL=A2AAJ9-1", "length": 732, "sequence": "MENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEVTEQETKVPKKTVIIEETITTVVKSPRGRRQSPGKSPSRSPSRRSASPRRPGLLAPERLYPPGTSPSRRLEVEQGRKAPVPALYVTEAEVHAPASQSQPKWLEVEETIEVRVKKTGSRGASPVREMTSRGEGILFTLPGGIPGRDPNANNSNNKSVYQEARTWGPAVVHVGEPFIFQVDSVGNVDWVAASPEPEQVRASQKEENTERQEGCSDGDENTFLMEEPQDTDSLQGRDPKILTHNGRVLTLADLEDYVPQEGETFGCGDSTPSTPDEPPCEVSVLQREISEPTVGQPVLLNVGRPPGTGATPSFFRPGSQVHSPESVSFLLREAWSGPVSAAPWTSSFHTHVQSSVDGSHGSFKTEVSTQTVSFGAVGETVTLHIDPDGGEAPGPSQG" } }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9#E9QQ96-1", "isoform_ac": "E9QQ96-1", "locus": { "end_pos": 59012659, "strand": "+", "start_pos": 59136375, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000052872", "id": "ENSMUST00000052872", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000049737", "id": "ENSMUSP00000049737", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E9QQ96-1|OBSCN_MOUSE Computationally mapped isoform of Obscurin OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=2 CANONICAL=A2AAJ9-1", "length": 7496, "sequence": "MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFKKRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCVSAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKFVANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQEPKLVFAKGQQAHSEVKAEAGNSATLSCEVTQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLMFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVADTRLMFAKEQQARTEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEGVHTSARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPVDVRWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRFRESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRALPAKFKDSLKNEEATEGTTATLSCELSKAAPVTWKKGPKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQEKTSATLTVRGLPAKFIEDLRSQEATEGATAILRCELSKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSSLPTKFTEGLRNEEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPSRFIEDLRSQEATEGTMATLRCQMSKTAPVEWKKGSETLRDGGRYSLRQDGPVCELQICDLAVEDAGEYSCVCGQEKTSATLSIKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKKEEATEGTMVTLRCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCELQIRDLAVEDAGEYLCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKALPPRFIEDLRSQEAREGTVATLRCRMSKAAPVEWRKGSETLKDGDRYSLRQEGNLCELQIRDLAVEDTEEYSCVCGQEKTSATLSVKALPAKFIEDLRSQEAPESSTVTLRCKLSKKASVVWKKGSETLRNGARYSLRQDGAVCELEIRDLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQNLQAEEGSMASLRCELSVPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADGCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTVRVPEVTVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRGWRLEVLEPPHDASVKAGMQVRFTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGEVTFAARDAVASARLSVLALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAPAPETRQAVVGEDICLELEVAADGGEVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEYRCGPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDSRVQHLRQEAEETAPDLSEGYSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGGPGISPLASKHEAQVTTSVKPQKQQEPVVPTCPPPGDLSAADLMDPSLDKAAVKIQAAFKGYKVRKEMKQQEGPVFSRTFGDTEAQVGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYTCQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEELFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGIGVEISLGEQGPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMSESAGFADLVGQSKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQVPGGDSDEETKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKLSPEWGPTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLERSPRVPAAVASQKTVIFRNVQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGRVQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEVTEQETKVPKKTVIIEETITTVVKSPRGRRQSPGKSPSRSPSRRSASPRRPGLLAPERLYPPGTSPSRRLEVEQGRKAPVPALYVTEAEVHAPASQSQPKWLEVEETIEVRVKKTGSRGASPVREMTSRGEGILFTLPGGIPGRDPNANNSNNKSVYQEARTWGPAVVHVGEPFIFQVDSVGNVDWVAASPEPEQVRASQKEENTERQEGCSDGDENTFLMEEPQDTDSLQGRDPKILTHNGRVLTLADLEDYVPQEGETFGCGDSTPSTPDEPPCEVSVLQREISEPTVGQPVLLNVGRPPGTGATPSFFRPGSQVHSPESVSFLLREAWSGPVSAAPWTSSFHTHVQSSVDGSHGSFKTEVSTQTVSFGAVGETVTLHIDPDGGEAPGPSQG" } }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9#F6TJX7-1", "isoform_ac": "F6TJX7-1", "locus": { "end_pos": 58994335, "strand": "+", "start_pos": 59000359, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000138587", "id": "ENSMUST00000138587", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000121092", "id": "ENSMUSP00000121092", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F6TJX7-1|F6TJX7_MOUSE Computationally mapped isoform of Obscurin OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=2 CANONICAL=A2AAJ9-1", "length": 923, "sequence": "KQEGSSQDSCRGKPASSCHSELGSGSQEGCGPPSSQSLGSLPPQSLKKELSTSCGPLFSEQPQAAPFPTQVSPLLGSEKEPQDGSLSEGPVPVPSSSPGSASQVDASLDTEGLSEAGDTCDFTPPPQRPQEQATTRKFSLESRGGYAGVAGYGTFAFGGDAGGMLGQGPLWARMAWAVSQSSEEQDEAATESPQPLESLGPIAEASGVPLRTSPSLTPWEEVEQVSLVQIRDLSGDAEAADTISLDISEVDPAYLNLSDLYDIKYLPFEFMIFRRVPKPIEQPESPGSETEAGQGLADFLEEAAWPWPGELGLRAGLEITEEPEEPGDLEALLGEAAVGRKRKWSPSRGLFQFPGRCLSGEEPVELGLRQRVKASMAHISRILKGRPEGPEREGPPRKKAGLASFRLSGLKGRDQAPSFLRELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKPVESCGPVTYIVQCCIEGGSWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPYSSPSEQVLLGGPNHLASEEESSRGRPAQLLPSTKTFAFQMQIRRGRFSVVRQCREKASGRALAAKIVPYQPEDKTAVLREYEALKRLHHPHLAQLHAAYLSPRHLVLILELCSGPELLPSLAERESYSESDVKDYLWQMLSATQYLHAQHILHLDLRSENMMVTEYNLLKVIDLGNAQSLDQEKVPAPENFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSGEYPESSEGTRDLQKGLRKGLIRLSRCYAGLSGGAVAFLQSSLCAQPWGRPCASTCLQCGWLTEEGPTGSRPTPVTFPTVRLRAFVREREKRRALLYKKHNLAQVR" } }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9#F7DCJ0-1", "isoform_ac": "F7DCJ0-1", "locus": { "end_pos": 59031953, "strand": "+", "start_pos": 59035037, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000132238", "id": "ENSMUST00000132238", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000116487", "id": "ENSMUSP00000116487", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F7DCJ0-1|OBSCN_MOUSE Computationally mapped isoform of Obscurin OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=1 CANONICAL=A2AAJ9-1", "length": 221, "sequence": "XEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMSESAGFADLVGQSKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQVPGGDSDEETKTPSASPRHGRSRPSSSVQESSSESEDGDSRGELTICHWELSRMPSF" } }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9#H7BX05-1", "isoform_ac": "H7BX05-1", "locus": { "end_pos": 58994335, "strand": "+", "start_pos": 59136375, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000047441", "id": "ENSMUST00000047441", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000038264", "id": "ENSMUSP00000038264", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|H7BX05-1|H7BX05_MOUSE Computationally mapped isoform of Non-specific serine/threonine protein kinase OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=2 CANONICAL=A2AAJ9-1", "length": 8032, "sequence": "MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFKKRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCVSAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKFVANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQDITDGYRDWGPAGPQKHMCKCAGAKIARYLGSSCYRFLQYDKGVWHWLEAALDTRQGKGTSSCSLHEKPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEGVHTSARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPVDVRWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRFRESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRALPAKFKDSLKNEEATEGTTATLSCELSKAAPVTWKKGPKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQEKTSATLTVRGLPAKFIEDLRSQEATEGATAILRCELSKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSSLPTKFTEGLRNEEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKKEEATEGTMVTLRCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKAPQVVFQQPLQNLQAEEGSMASLRCELSVPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADGCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTVRVPEVTVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAPAPETRQAVVGEDICLELEVAADGGEVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEYRCGPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDSRVQHLRQEAEETAPDLSEGYSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGGPGISPLASKHEAQVTTSVKPQKQQEPVVPTCPPPGDLSAADLMDPSLDKAAVKIQAAFKGYKVRKEMKQQEGPVFSRTFGDTEAQVGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYTCQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEELFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGIGVEISLGEQGPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMSESAGFADLVGQSKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQVPGGDSDEETKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKLSPEWGPTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLERSPRVPAAVASQKTVIFRNVQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGRVQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEGAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELLVHGGDKLDAENQVYRRKLHSFYDVQEEIGRGVFGFVKRVQHKGNKMFCAAKFIPLRSKTRAQAYQERDILATLGHPLVTGLLDQFETRKTLILILELCSSEELLDRLFKKGVVTEAEVKVYIQQLVEGLHYLHSHGILHLDIKPPNILMVHPAREDIKICDFGFAQKITPSEPQYSKYGSPEFVSPEIIEQNPVSEGSDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPTAAHLSEDAKDFIKATLQRTPRARPSTSQCLAHPWFLKSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSILVMRSIPELLQGPPDSPSLGVARHLRGEASGASSSSSSSDNELAPFARAKSLPPSPVTHSPLLHPRGFLRPSASLPEETEASMPTADAAVPASPQSAGPPASPGCVPRHSVISSLFYQQAGEGAERGNKTSGAKRHPARRRHLLKGGYIARALPGLREPLMEYSLLEEEAAREEQASLMTKTPSFETALRLPSSSVREVPGRSHSLDNPPVTTGPSPEACKEQLLFPPSTGLTHETTAKDRGHKEGFLQESVPFPPMSGDSRPGKQEGSSQDSCRGKPASSCHSELGSGSQEGCGPPSSQSLGSLPPQSLKKELSTSCGPLFSEQPQAAPFPTQVSPLLGSEKEPQDGSLSEGPVPVPSSSPGSASQVDASLDTEGLSEAGDTCDFTPPPQRPQEQATTRKFSLESRGGYAGVAGYGTFAFGGDAGGMLGQGPLWARMAWAVSQSSEEQDEAATESPQPLESLGPIAEASGVPLRTSPSLTPWEEVEQVSLVQIRDLSGDAEAADTISLDISEVDPAYLNLSDLYDIKYLPFEFMIFRRVPKPIEQPESPGSETEAGQGLADFLEEAAWPWPGELGLRAGLEITEEPEEPGDLEALLGEAAVGRKRKWSPSRGLFQFPGRCLSGEEPVELGLRQRVKASMAHISRILKGRPEGPEREGPPRKKAGLASFRLSGLKGRDQELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKPVESCGPVTYIVQCCIEGGSWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPYSSPSEQVLLGGPNHLASEEESSRGRPAQLLPSTKTFAFQMQIRRGRFSVVRQCREKASGRALAAKIVPYQPEDKTAVLREYEALKRLHHPHLAQLHAAYLSPRHLVLILELCSGPELLPSLAERESYSESDVKDYLWQMLSATQYLHAQHILHLDLRSENMMVTEYNLLKVIDLGNAQSLDQEKVPAPENFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSGEYPESSEGTRDLQKGLRKGLIRLSRCYAGLSGGAVAFLQSSLCAQPWGRPCASTCLQCGWLTEEGPTGSRPTPVTFPTVRLRAFVREREKRRALLYKKHNLAQVR" } }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9#J9JIB2-1", "isoform_ac": "J9JIB2-1", "locus": { "end_pos": 59073108, "strand": "+", "start_pos": 59079692, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000133040", "id": "ENSMUST00000133040", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000122181", "id": "ENSMUSP00000122181", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|J9JIB2-1|J9JIB2_MOUSE Computationally mapped isoform of Obscurin OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=2 CANONICAL=A2AAJ9-1", "length": 849, "sequence": "AGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRSVQITKPLEDVEVMEKEGATFSCEVSHDEVPGLWFRESSKLRPSDNVRIRQEGRTYTLIFRRVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVH" } }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9#Z4YJE4-1", "isoform_ac": "Z4YJE4-1", "locus": { "end_pos": 59013777, "strand": "+", "start_pos": 59136375, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000020732", "id": "ENSMUST00000020732", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000020732", "id": "ENSMUSP00000020732", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|Z4YJE4-1|Z4YJE4_MOUSE Computationally mapped isoform of Non-specific serine/threonine protein kinase OS=Mus musculus OX=10090 GN=Obscn PE=1 SV=3 CANONICAL=A2AAJ9-1", "length": 7176, "sequence": "MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFKKRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCVSAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKFVANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQDITDGYRDWGPAGPQKHMCKCAGAKIARYLGSSCYRFLQYDKGVWHWLEAALDTRQGKGTSSCSLHEKPKLVFAKGQQAHSEVKAEAGNSATLSCEVTQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQANSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLMFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVADTRLMFAKEQQARTEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGLVAFRAEGVHTSARLIVTELPVSFTRVLQDVVATQKEKVTLECELSRPVDVRWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSITIVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEEGRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGTLTLQCEVSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPLEDQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPASVVTWRKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRFRESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRALPAKFKDSLKNEEATEGTTATLSCELSKAAPVTWKKGPKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQEKTSATLTVRGLPAKFIEDLRSQEATEGATAILRCELSKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQIRGLAVVDTGTYSSLPTKFTEGLRNEEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIEDSGEYTCVCGQEKTSATLSVKALPSRFIEDLRSQEATEGTMATLRCQMSKTAPVEWKKGSETLRDGGRYSLRQDGPVCELQICDLAVEDAGEYSCVCGQEKTSATLSIKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLGDGGRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQIHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKKEEATEGTMVTLRCQMSKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCELQIRDLAVEDAGEYLCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKALPPRFIEDLRSQEAREGTVATLRCRMSKAAPVEWRKGSETLKDGDRYSLRQEGNLCELQIRDLAVEDTEEYSCVCGQEKTSATLSVKALPAKFIEDLRSQEAPESSTVTLRCKLSKKASVVWKKGSETLRNGARYSLRQDGAVCELEIRDLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQNLQAEEGSMASLRCELSVPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADGCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTVRVPEVTVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVPLQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRGWRLEVLEPPHDASVKAGMQVRFTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGEVTFAARDAVASARLSVLALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAPAPETRQAVVGEDICLELEVAADGGEVVWHKGTERIQPGGHFEVLSRGQRQMLVIKGFRTEDQGEYRCGPIQGLPSSGAATFNVVMTSGSGDEVPAQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDSRVQHLRQEAEETAPDLSEGYSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGGPGISPLASKHEAQVTTSVKPQKQQEPVVPTCPPPGDLSAADLMDPSLDKAAVKIQAAFKGYKVRKEMKQQEGPVFSRTFGDTEAQVGDVLRLECVLATKTDMRACWLKDGIELTDGRHYHIDQLKDGTCSLLVTGLAPTDSGRYTCQVSTKSGRVSHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKSPAELSEEELFLSADEGPGEPEEPADWQTYREDENFVCIRFESLAEARQAVTCFRNMFATMGIGVEISLGEQGPRGVEMRIGKVAPTVTPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQGTSQAVSAQMSESAGFADLVGQSKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVSAKISQAKLQVPGGDSDEETKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKLSPEWGPTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLERSPRVPAAVASQKTVIFRNVQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGRVQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNYLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARDQHHREQIVAAVEERRPSPP" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:380698", "resource": "KEGG Pathway", "id": "mmu:380698", "name": "" } ], "reaction_participants": [], "function": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9#function", "annotation": "Isoform 2 and isoform 3: bind phosphatidylinositol bisphosphates (PIP2s) via their PH domains and negatively regulate the PI3K/AKT/mTOR signaling pathway, thus contributing to the regulation of cardiomyocyte size and adhesion.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9#function", "id": "A2AAJ9", "database": "UniProtKB" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164983.2", "annotation": "Results support a role of obscurin in mediating the subcellular localization of small ankyrin1 isoforms in striated muscle cells.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164983.2", "id": "NP_001164983.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954603.3", "annotation": "Results support a role of obscurin in mediating the subcellular localization of small ankyrin1 isoforms in striated muscle cells.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954603.3", "id": "NP_954603.3", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164983.2", "annotation": "Skeletal muscle-specific Obsl1 knockouts show a benign phenotype similar to obscurin knockouts. Only deletion of both proteins and removal of their functional redundancy revealed their roles for sarcolemmal stability and sarcoplasmic reticulum organization. Publication Status: Online-Only", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164983.2", "id": "NP_001164983.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954603.3", "annotation": "Skeletal muscle-specific Obsl1 knockouts show a benign phenotype similar to obscurin knockouts. Only deletion of both proteins and removal of their functional redundancy revealed their roles for sarcolemmal stability and sarcoplasmic reticulum organization. Publication Status: Online-Only", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954603.3", "id": "NP_954603.3", "database": "RefSeq" } ] }, { "url": "https://www.uniprot.org/uniprot/A2AAJ9#function", "annotation": "Structural component of striated muscles which plays a role in myofibrillogenesis. Probably involved in the assembly of myosin into sarcomeric A bands in striated muscle (By similarity). Has serine/threonine protein kinase activity and phosphorylates N-cadherin CDH2 and sodium/potassium-transporting ATPase subunit ATP1B1 (PubMed:23392350). Binds (via the PH domain) strongly to phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), and to a lesser extent to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), phosphatidylinositol 5-phosphate (PtdIns(5)P) and phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) (By similarity).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9#function", "id": "A2AAJ9", "database": "UniProtKB" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164983.2", "annotation": "The Rho-GEF domain of obscurin interacts with RanBP9 and that both can interact with the N-terminal region of titin to influence the formation of the Z-disk and A/I junction", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164983.2", "id": "NP_001164983.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954603.3", "annotation": "The Rho-GEF domain of obscurin interacts with RanBP9 and that both can interact with the N-terminal region of titin to influence the formation of the Z-disk and A/I junction", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954603.3", "id": "NP_954603.3", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164983.2", "annotation": "These findings implicate small obscurins in the maintenance of cardiomyocyte size and coupling.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164983.2", "id": "NP_001164983.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954603.3", "annotation": "These findings implicate small obscurins in the maintenance of cardiomyocyte size and coupling.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954603.3", "id": "NP_954603.3", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q5VST9-1", "protein_name": "Obscurin", "sequence": { "length": 7968, "sequence": "MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQAVEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVAELEPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELSKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELSKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPARFIEDVKNQEAREGATAVLQCELNSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAPVEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLWCELSKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELSKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLAQGSICPAAATFQVALSPASVDEAPQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDGRSQRLPQEAEEVAPDLSEGYSTADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAGRPGTSPLASKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADWQTYREDEHFICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQGLETASFADLGGQRKEEPLAAKEALGHLSLAEVGTEEFLQKLTSQITEMVSAKITQAKLQVPGGDSDEDSKTPSASPRHGRSRPSSSIQESSSESEDGDARGEIFDIYVVTADYLPLGAEQDAITLREGQYVEVLDAAHPLRWLVRTKPTKSSPSRQGWVSPAYLDRRLKLSPEWGAAEAPEFPGEAVSEDEYKARLSSVIQELLSSEQAFVEELQFLQSHHLQHLERCPHVPIAVAGQKAVIFRNVRDIGRFHSSFLQELQQCDTDDDVAMCFIKNQAAFEQYLEFLVGRVQAESVVVSTAIQEFYKKYAEEALLAGDPSQPPPPPLQHYLEQPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLQALGEPIRQGHFIVWEGAPGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTVSYVFRNMMKLSSIDLNDQVEGDDRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEICGIQQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTSVLKRLLGPKAPGPSTGDLTGPGPCPRGAPALQETGSQPPVTGTSEAPAVPPRVPQPLLHEGPEQEPEAIARAQEWTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQSHRRKLHSFYEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYRERDILAALSHPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGVVTEAEVKVYIQQLVEGLHYLHSHGVLHLDIKPSNILMVHPAREDIKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWFLKSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSILVMRSIPELLRGPPDSPSLGVARHLCRDTGGSSSSSSSSDNELAPFARAKSLPPSPVTHSPLLHPRGFLRPSASLPEEAEASERSTEAPAPPASPEGAGPPAAQGCVPRHSVIRSLFYHQAGESPEHGALAPGSRRHPARRRHLLKGGYIAGALPGLREPLMEHRVLEEEAAREEQATLLAKAPSFETALRLPASGTHLAPGHSHSLEHDSPSTPRPSSEACGEAQRLPSAPSGGAPIRDMGHPQGSKQLPSTGGHPGTAQPERPSPDSPWGQPAPFCHPKQGSAPQEGCSPHPAVAPCPPGSFPPGSCKEAPLVPSSPFLGQPQAPPAPAKASPPLDSKMGPGDISLPGRPKPGPCSSPGSASQASSSQVSSLRVGSSQVGTEPGPSLDAEGWTQEAEDLSDSTPTLQRPQEQATMRKFSLGGRGGYAGVAGYGTFAFGGDAGGMLGQGPMWARIAWAVSQSEEEEQEEARAESQSEEQQEARAESPLPQVSARPVPEVGRAPTRSSPEPTPWEDIGQVSLVQIRDLSGDAEAADTISLDISEVDPAYLNLSDLYDIKYLPFEFMIFRKVPKSAQPEPPSPMAEEELAEFPEPTWPWPGELGPHAGLEITEESEDVDALLAEAAVGRKRKWSSPSRSLFHFPGRHLPLDEPAELGLRERVKASVEHISRILKGRPEGLEKEGPPRKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVTYIVQCSLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMGPYSSPSEQVLLGGPSHLASEEESQGRSAQPLPSTKTFAFQTQIQRGRFSVVRQCWEKASGRALAAKIIPYHPKDKTAVLREYEALKGLRHPHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERASYSESEVKDYLWQMLSATQYLHNQHILHLDLRSENMIITEYNLLKVVDLGNAQSLSQEKVLPSDKFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSAEYPVSSEGARDLQRGLRKGLVRLSRCYAGLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWLTEEGPACSRPAPVTFPTARLRVFVRNREKRRALLYKRHNLAQVR" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/70869", "id": "70869", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "OBSCN", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_954603.3", "ac": "NP_954603.3", "name": "obscurin isoform 2", "summary": "The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 800 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein is one of three giant sacromeric signaling proteins that includes titin and nebulin. It may have a role in the organization of myofibrils during assembly and also may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been described although the full-length nature is not known for all splicing variants. [provided by RefSeq, Jan 2010]." }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "pmid": "28826662", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "pmid": "23392350", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "protein kinase activity", "id": "GO:0004672" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "pmid": "23392350", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "cadherin binding", "id": "GO:0045296" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010314", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "phosphatidylinositol-5-phosphate binding", "id": "GO:0010314" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "protein serine/threonine kinase activity", "id": "GO:0004674" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "calmodulin binding", "id": "GO:0005516" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "ATP binding", "id": "GO:0005524" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043325", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "phosphatidylinositol-3,4-bisphosphate binding", "id": "GO:0043325" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "metal ion binding", "id": "GO:0046872" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031432", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "titin binding", "id": "GO:0031432" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030506", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "ankyrin binding", "id": "GO:0030506" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "protein kinase activity", "id": "GO:0004672" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "nucleotide binding", "id": "GO:0000166" } ], "total": 18, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "pmid": "23392350", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": "UniProtKB" } ], "name": "extracellular space", "id": "GO:0005615" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "pmid": "28826662", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AAJ9", "id": "A2AAJ9", "database": 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