{
    "uniprot_canonical_ac": "A2A716-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A2A716-1|A2A716_MOUSE Isoform 1 of Oxysterol-binding protein  OS=Mus musculus OX=10090 GN=Osbpl7 PE=1 SV=2 CANONICAL=A2A716-1", 
        "length": 837, 
        "sequence": "MDFQERDTPSLAESTQSSKPSSTQQASELWEVMEEPRGRLGADDIMPERQEGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKVHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFHSWVAQLRAHRLAQRLDMPSATHRKAPGTQMLTAGSASALPGVGPREKVSSWLRDSDGLDRCSHALSECQGKLQELHRLLQSLESLHRIPSAPVIPTHQTSVTTERPKKGKRTSRMWCTQGFAKDDTIGRVGRLHGSVPNLSRYLESRDTSGPRGLPPPDYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRDLHQGSELSRMVVSEAPDGQRRLHSLSISSDTTADSFSSLNPEEQEALYMKGRELTPQLSQSSVLSLADSHTEFFDACEVLLSASSSENEGSEEEESCASEITTSLSEEVLDIRGADRYQKGPCVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIHEVQGAVLSRSGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTSELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW"
    }, 
    "uniprot_id": "A2A716_MOUSE", 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2A716", 
                    "id": "A2A716", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "reaction_enzymes": [], 
    "publication": [], 
    "uniprot_ac": "A2A716", 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A716", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Osbpl7"
        }
    ], 
    "reactions": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A716#A2A716-1", 
            "isoform_ac": "A2A716-1", 
            "locus": {
                "end_pos": 97052302, 
                "strand": "-", 
                "start_pos": 97068047, 
                "chromosome": "11", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000090020", 
                        "id": "ENSMUST00000090020", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000087474", 
                        "id": "ENSMUSP00000087474", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A2A716-1|A2A716_MOUSE Isoform 1 of Oxysterol-binding protein  OS=Mus musculus OX=10090 GN=Osbpl7 PE=1 SV=2 CANONICAL=A2A716-1", 
                "length": 837, 
                "sequence": "MDFQERDTPSLAESTQSSKPSSTQQASELWEVMEEPRGRLGADDIMPERQEGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKVHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFHSWVAQLRAHRLAQRLDMPSATHRKAPGTQMLTAGSASALPGVGPREKVSSWLRDSDGLDRCSHALSECQGKLQELHRLLQSLESLHRIPSAPVIPTHQTSVTTERPKKGKRTSRMWCTQGFAKDDTIGRVGRLHGSVPNLSRYLESRDTSGPRGLPPPDYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRDLHQGSELSRMVVSEAPDGQRRLHSLSISSDTTADSFSSLNPEEQEALYMKGRELTPQLSQSSVLSLADSHTEFFDACEVLLSASSSENEGSEEEESCASEITTSLSEEVLDIRGADRYQKGPCVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIHEVQGAVLSRSGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTSELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A716#F8VQM4-1", 
            "isoform_ac": "F8VQM4-1", 
            "locus": {
                "end_pos": 97052546, 
                "strand": "-", 
                "start_pos": 97068047, 
                "chromosome": "11", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000168565", 
                        "id": "ENSMUST00000168565", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000126902", 
                        "id": "ENSMUSP00000126902", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|F8VQM4-1|A2A716_MOUSE Computationally mapped isoform of Oxysterol-binding protein  OS=Mus musculus OX=10090 GN=Osbpl7 PE=1 SV=1 CANONICAL=A2A716-1", 
                "length": 791, 
                "sequence": "MPERQEGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKVHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFHSWVAQLRAHRLAQRLDMPSATHRKAPGTQMLTAGSASALPGVGPREKVSSWLRDSDGLDRCSHALSECQGKLQELHRLLQSLESLHRIPSAPVIPTHQTSVTTERPKKGKRTSRMWCTQGFAKDDTIGRVGRLHGSVPNLSRYLESRDTSGPRGLPPPDYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRDLHQGSELSRMVVSEAPDGQRRLHSLSISSDTTADSFSSLNPEEQEALYMKGRELTPQLSQSSVLSLADSHTEFFDACEVLLSASSSENEVREEGSCASEITTSLSEEVLDIRGADRYQKGPCVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIHEVQGAVLSRSGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTSELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW"
            }
        }
    ], 
    "pathway": [], 
    "reaction_participants": [], 
    "function": [], 
    "orthologs": [], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }
    ], 
    "refseq": {}, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A716", 
                                "id": "A2A716", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cholesterol binding", 
                        "id": "GO:0015485"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A716", 
                                "id": "A2A716", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytosol", 
                        "id": "GO:0005829"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A716", 
                                "id": "A2A716", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "plasma membrane", 
                        "id": "GO:0005886"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A716", 
                                "id": "A2A716", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "perinuclear endoplasmic reticulum", 
                        "id": "GO:0097038"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A716", 
                                "id": "A2A716", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "autophagosome", 
                        "id": "GO:0005776"
                    }
                ], 
                "total": 4, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A716", 
                                "id": "A2A716", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "lipid transport", 
                        "id": "GO:0006869"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071397", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A716", 
                                "id": "A2A716", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cellular response to cholesterol", 
                        "id": "GO:0071397"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901800", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A716", 
                                "id": "A2A716", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of proteasomal protein catabolic process", 
                        "id": "GO:1901800"
                    }
                ], 
                "total": 3, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 272, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 270
        }, 
        {
            "end_pos": 619, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 617
        }, 
        {
            "end_pos": 818, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 816
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000038534", 
            "id": "ENSMUSG00000038534", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000648", 
            "id": "IPR000648", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", 
            "id": "IPR001849", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", 
            "id": "IPR011993", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018494", 
            "id": "IPR018494", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR037239", 
            "id": "IPR037239", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR041680", 
            "id": "IPR041680", 
            "database": "InterPro"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:1918490", 
            "id": "1918490", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/SWVTQLR/", 
            "id": "SWVTQLR", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=542090at2759", 
            "id": "542090at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972", 
            "id": "PTHR10972", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF01237", 
            "id": "PF01237", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF15409", 
            "id": "PF15409", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074903", 
            "id": "NP_001074903", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074903.1", 
            "id": "NP_001074903.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A716", 
            "id": "A2A716", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A716-1", 
            "id": "A2A716-1", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/F8VQM4", 
            "id": "F8VQM4", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/F8VQM4-1", 
            "id": "F8VQM4-1", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 95030.0, 
        "chemical_mass": 95030.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A716", 
            "name": "Osbpl7", 
            "locus": {
                "end_pos": 97068904, 
                "strand": "+", 
                "start_pos": 97050628, 
                "chromosome": "11", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000038534", 
                        "id": "ENSMUSG00000038534", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A716#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Oxysterol-binding protein"
        }
    ]
}