{
    "uniprot_canonical_ac": "A2A559-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2A559-1|PGAP3_MOUSE Isoform 1 of Post-GPI attachment to proteins factor 3  OS=Mus musculus OX=10090 GN=Pgap3 PE=2 SV=1 CANONICAL=A2A559-1", 
        "length": 320, 
        "sequence": "MAKRTAPLLLLTLAVGLAGGSQGDREPVYRDCVLRCEERNCSGDALKHFRSRQPIYMSLAGWTCRDDCKYECMWFTVGLYLQEGHRVPQFHGKWPFSRFLFIQEPASAVASLLNGLASLVMLCRYRASVPASSPMYHTCMAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASAVILHSVYLCCVRTVGLQHPSVASAFGALLLLLLTGHISYLSLVHFDYGYNMMANVAIGLVNLAWWLVWCLRNRQRLPHTRRCMVVVVLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHTLFFRFLEDDSLYLLKESGAMFKLD"
    }, 
    "uniprot_id": "PGAP3_MOUSE", 
    "glycation": [], 
    "keywords": [
        "glycoprotein", 
        "predicted.uniprotkb_gly"
    ], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2A559", 
                    "id": "A2A559", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "reaction_enzymes": [], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/22227195", 
                    "type": "PubMed", 
                    "id": "22227195"
                }
            ], 
            "title": "Enhanced response of T lymphocytes from Pgap3 knockout mouse: Insight into roles of fatty acid remodeling of GPI anchored proteins.", 
            "journal": "Biochemical and biophysical research communications", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028709.2", 
                    "id": "NP_001028709.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Murakami H, Wang Y, Hasuwa H, Maeda Y, Kinoshita T, Murakami Y", 
            "date": "2012"
        }
    ], 
    "uniprot_ac": "A2A559", 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A559", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "CAB; CAB2; D430035D22Rik; Per; Perld1"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A559", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Perld1"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A559", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Pgap3"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A559", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Pgap3"
        }
    ], 
    "reactions": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A559#A2A559-1", 
            "isoform_ac": "A2A559-1", 
            "locus": {
                "end_pos": 98390041, 
                "strand": "+", 
                "start_pos": 98400395, 
                "chromosome": "11", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000090827", 
                        "id": "ENSMUST00000090827", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000088337", 
                        "id": "ENSMUSP00000088337", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2A559-1|PGAP3_MOUSE Isoform 1 of Post-GPI attachment to proteins factor 3  OS=Mus musculus OX=10090 GN=Pgap3 PE=2 SV=1 CANONICAL=A2A559-1", 
                "length": 320, 
                "sequence": "MAKRTAPLLLLTLAVGLAGGSQGDREPVYRDCVLRCEERNCSGDALKHFRSRQPIYMSLAGWTCRDDCKYECMWFTVGLYLQEGHRVPQFHGKWPFSRFLFIQEPASAVASLLNGLASLVMLCRYRASVPASSPMYHTCMAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASAVILHSVYLCCVRTVGLQHPSVASAFGALLLLLLTGHISYLSLVHFDYGYNMMANVAIGLVNLAWWLVWCLRNRQRLPHTRRCMVVVVLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHTLFFRFLEDDSLYLLKESGAMFKLD"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A559#A2A559-2", 
            "isoform_ac": "A2A559-2", 
            "locus": {
                "end_pos": 98390041, 
                "strand": "+", 
                "start_pos": 98400395, 
                "chromosome": "11", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000128897", 
                        "id": "ENSMUST00000128897", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000119668", 
                        "id": "ENSMUSP00000119668", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2A559-2|PGAP3_MOUSE Isoform 2 of Post-GPI attachment to proteins factor 3  OS=Mus musculus OX=10090 GN=Pgap3 PE=2 SV=1 CANONICAL=A2A559-1", 
                "length": 269, 
                "sequence": "MAKRTAPLLLLTLAVGLAGGSQGDREPVYRDCVLRCEERNCSGDALKHFRSRQPIYMSLAGWTCRDDCKYECMWFTVGLYLQEGHRVPQFHGKVSLNAWFWSTVFHTRDTDLTEKMDYFCASAVILHSVYLCCVRTVGLQHPSVASAFGALLLLLLTGHISYLSLVHFDYGYNMMANVAIGLVNLAWWLVWCLRNRQRLPHTRRCMVVVVLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHTLFFRFLEDDSLYLLKESGAMFKLD"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:320655", 
            "resource": "KEGG Pathway", 
            "id": "mmu:320655", 
            "name": ""
        }
    ], 
    "reaction_participants": [], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A559#function", 
            "annotation": "Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (By similarity).", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2A559#function", 
                    "id": "A2A559", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028709.2", 
            "annotation": "The response of T cells was enhanced in Pgap3 knockout mice in both in vitro and in vivo studies, including alloreactive response, antigen-specific immune response, and experimental autoimmune encephalomyelitis.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028709.2", 
                    "id": "NP_001028709.2", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "B1WBW5-1", 
            "protein_name": "Post-GPI attachment to proteins factor 3", 
            "sequence": {
                "length": 320, 
                "sequence": "MARRTAPLLLLTLAVGLAGSSQGDREPVYRDCVLRCEERNCSGDALKHFRSRQPIYMSLAGWTCRDDCKYECMWLTVGLYLQEGYRVPQFHGKWPFSRFLFIQEPASALASLLNGLASLVMLCRYRASVPASSPMYHTCMAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASAVILHSVYLCCVRTVGLQHPTVASAFGALLLLLLTGHISYLSLVHFDYGYNMMANVAIGLVNLAWWLVWCLRNHRRLPHTRRCMVVVVLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHTLFFRFLEDDSLYLLKESEAMFKLD"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A2A559/", 
                    "id": "A2A559", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/5484", 
                    "id": "5484", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Rat", 
            "organism": "Rattus norvegicus", 
            "gene_name": "Pgap3", 
            "tax_id": 10116
        }, 
        {
            "uniprot_canonical_ac": "Q96FM1-1", 
            "protein_name": "Post-GPI attachment to proteins factor 3", 
            "sequence": {
                "length": 320, 
                "sequence": "MAGLAARLVLLAGAAALASGSQGDREPVYRDCVLQCEEQNCSGGALNHFRSRQPIYMSLAGWTCRDDCKYECMWVTVGLYLQEGHKVPQFHGKWPFSRFLFFQEPASAVASFLNGLASLVMLCRYRTFVPASSPMYHTCVAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASTVILHSIYLCCVRTVGLQHPAVVSAFRALLLLMLTVHVSYLSLIRFDYGYNLVANVAIGLVNVVWWLAWCLWNQRRLPHVRKCVVVVLLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHVLFFSFLEDDSLYLLKESEDKFKLD"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A2A559/", 
                    "id": "A2A559", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/5484", 
                    "id": "5484", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "PGAP3", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028709.2", 
        "ac": "NP_001028709.2", 
        "name": "post-GPI attachment to proteins factor 3 precursor", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016788", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A559", 
                                "id": "A2A559", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "hydrolase activity, acting on ester bonds", 
                        "id": "GO:0016788"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031227", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A559", 
                                "id": "A2A559", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "intrinsic component of endoplasmic reticulum membrane", 
                        "id": "GO:0031227"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A559", 
                                "id": "A2A559", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Golgi membrane", 
                        "id": "GO:0000139"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A559", 
                                "id": "A2A559", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }
                ], 
                "total": 3, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006505", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A559", 
                                "id": "A2A559", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "GPI anchor metabolic process", 
                        "id": "GO:0006505"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A559", 
                                "id": "A2A559", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "GPI anchor biosynthetic process", 
                        "id": "GO:0006506"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 42, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 40
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000038208", 
            "id": "ENSMUSG00000038208", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/320655", 
            "id": "320655", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007217", 
            "id": "IPR007217", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:320655", 
            "id": "mmu:320655", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:2444461", 
            "id": "2444461", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/LGMQEPF/", 
            "id": "LGMQEPF", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=828384at2759", 
            "id": "828384at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13148", 
            "id": "PTHR13148", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF04080", 
            "id": "PF04080", 
            "database": "Pfam"
        }, 
        {
            "url": "http://purl.obolibrary.org/obo/PR_PR_A2A559", 
            "id": "PR_A2A559", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028709", 
            "id": "NP_001028709", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028709.2", 
            "id": "NP_001028709.2", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A559", 
            "id": "A2A559", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A559-1", 
            "id": "A2A559-1", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A559-2", 
            "id": "A2A559-2", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [
        {
            "comment": "N-linked (GlcNAc...) asparagine", 
            "site_category": "predicted", 
            "end_pos": 40, 
            "residue": "Asn", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2A559#ptm_processing", 
                    "id": "A2A559", 
                    "database": "UniProtKB"
                }
            ], 
            "subtype": "", 
            "relation": "attached", 
            "start_pos": 40, 
            "glytoucan_ac": "", 
            "type": "N-linked"
        }
    ], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 36528.0, 
        "chemical_mass": 36528.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A559", 
            "name": "Pgap3", 
            "locus": {
                "end_pos": 98388677, 
                "strand": "-", 
                "start_pos": 98400490, 
                "chromosome": "11", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000038208", 
                        "id": "ENSMUSG00000038208", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A559#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "PER1-like domain-containing protein 1"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A559#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Post-GPI attachment to proteins factor 3"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A559", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "per1-like domain containing 1; post-GPI attachment to proteins factor 3; PER1-like domain-containing protein 1"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A559", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "post-GPI attachment to proteins factor 3 precursor"
        }
    ]
}