{ "uniprot_canonical_ac": "A4KWA8-1", "ptm_annotation": [], "sequence": { "header": "sp|A4KWA8-1|CL2D6_RAT Isoform 1 of C-type lectin domain family 2 member D6 OS=Rattus norvegicus OX=10116 GN=Clec2d6 PE=2 SV=1 CANONICAL=A4KWA8-1", "length": 233, "sequence": "MPSSAHLQDSPPLLSRTLTQNEGQTSLRQSSSCGPSATSASESLSGYTESRIPHSEMLQEKFHGIILPESPAKLLCCCAVIVVLSVAVVALSVALSVKKTPQISTVKTYAACPRNWIGVGNKCYYFNETARNWTFSQTLCKEQEAELARFDTEEELNFLRRYKGSPGCWIGLHRESSAHNWTWTDNTAYNKLLPIRGVEKHGFLSDNGISSSRDYIKRNSICSKLNSYTSQCQ" }, "uniprot_id": "CL2D6_RAT", "glycation": [], "keywords": [ "glycoprotein", "predicted.uniprotkb_gly" ], "species": [ { "common_name": "Rat", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8", "id": "A4KWA8", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "reaction_enzymes": [], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/17462921", "type": "PubMed", "id": "17462921" } ], "title": "Cytomegalovirus evasion of innate immunity by subversion of the NKR-P1B:Ocil/Clr-b missing-self axis.", "journal": "Immunity", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8", "id": "A4KWA8", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078873.1", "id": "NP_001078873.1", "database": "RefSeq" } ], "authors": "Chen P., Voigt S., Carlyle J.R., Chou W., Mesci A., Ettinger J., Fine J.H.", "date": "2007" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/19130483", "type": "PubMed", "id": "19130483" } ], "title": "Two major groups of rat NKR-P1 receptors can be distinguished based on chromosomal localization, phylogenetic analysis and Clr ligand binding.", "journal": "European journal of immunology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078873.1", "id": "NP_001078873.1", "database": "RefSeq" } ], "authors": "Kveberg L, Dai KZ, Westgaard IH, Daws MR, Fossum S, Naper C, Vaage JT", "date": "2009" } ], "uniprot_ac": "A4KWA8", "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A4KWA8", "type": "synonym", "resource": "RefSeq", "name": "Clec2d6" }, { "url": "https://www.uniprot.org/uniprot/A4KWA8", "type": "recommended", "resource": "UniProtKB", "name": "Clec2d6" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A4KWA8", "type": "synonym", "resource": "RefSeq", "name": "Clec2dl1" }, { "url": "https://www.uniprot.org/uniprot/A4KWA8", "type": "recommended", "resource": "UniProtKB", "name": "Clec2dl1" }, { "url": "https://www.uniprot.org/uniprot/A4KWA8", "type": "synonym", "resource": "UniProtKB", "name": "Clec2d" } ], "reactions": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8#A0A0G2JWN5-1", "isoform_ac": "A0A0G2JWN5-1", "locus": { "end_pos": 162281580, "strand": "-", "start_pos": 162400244, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000087850", "id": "ENSRNOT00000087850", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000069949", "id": "ENSRNOP00000069949", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2JWN5-1|A0A0G2JWN5_RAT Computationally mapped isoform of C-type lectin domain family 2 member D-like 1 OS=Rattus norvegicus OX=10116 GN=Clec2dl1 PE=4 SV=1 CANONICAL=A4KWA8-1", "length": 233, "sequence": "MPSSAHLQDPPPLLSRTLTQNEGQTSLRQSSSCGLSAASASESLSGSTESRIPHSEMLQEKFHGIILPESPAKLLCCCAVIVVLSVAVVALSVALSVKKTPQISTVKTYAACPRNWIGVGNKCYYFNETARNWTFSQTLCKEQEAELARFDTEEELNFLRRYKGSPGCWIGLHRESSAHNWTWTDNTAYNKLLPIRGVEKHGFLSDNGISSSRDYIKRNSICSKLNSYTSQCQ" } }, { "url": "https://www.uniprot.org/uniprot/A4KWA8#A4KWA8-1", "isoform_ac": "A4KWA8-1", "locus": { "end_pos": 162392869, "strand": "-", "start_pos": 162400244, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000047790", "id": "ENSRNOT00000047790", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000048461", "id": "ENSRNOP00000048461", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A4KWA8-1|CL2D6_RAT Isoform 1 of C-type lectin domain family 2 member D6 OS=Rattus norvegicus OX=10116 GN=Clec2d6 PE=2 SV=1 CANONICAL=A4KWA8-1", "length": 233, "sequence": "MPSSAHLQDSPPLLSRTLTQNEGQTSLRQSSSCGPSATSASESLSGYTESRIPHSEMLQEKFHGIILPESPAKLLCCCAVIVVLSVAVVALSVALSVKKTPQISTVKTYAACPRNWIGVGNKCYYFNETARNWTFSQTLCKEQEAELARFDTEEELNFLRRYKGSPGCWIGLHRESSAHNWTWTDNTAYNKLLPIRGVEKHGFLSDNGISSSRDYIKRNSICSKLNSYTSQCQ" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:689790", "resource": "KEGG Pathway", "id": "rno:689790", "name": "" } ], "reaction_participants": [], "function": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8#function", "annotation": "Lectin-type cell surface receptor.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8#function", "id": "A4KWA8", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "A4KWA5-1", "protein_name": "C-type lectin domain family 2 member D2", "sequence": { "length": 233, "sequence": "MPSSAHLQDAPPLLSRTLTQDEEQTSLRQSSSCGLSAASASESLSGSTKSRIPHSKMLQGNLPRIISPESPAKLPCCYGVIMVLSVAVVALSVALSVKKTPQILTVKTYAACPRNWIGVGNKCYYFNETPSNWTFSQTLCKAQEAELARFDTEEELNFLKRHKGSSGYWIGLHRESSSQPWKWTDNTAYNNLVPIGGDEKHGFLSDNGFSSGRGYIVRKSICSKPNSYTSQCQ" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/134308", "id": "134308", "database": "MGI" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "gene_name": "Clec2d2", "tax_id": 10116 }, { "uniprot_canonical_ac": "A4KWA6-1", "protein_name": "C-type lectin domain family 2 member D3", "sequence": { "length": 252, "sequence": "MSSSAHLQDAPPLLSGTLTQNEGQTSLRQSSSCGPSAASASESLSGYTESRIPHSKVRQGKGLRSIFPESRVKRYCCYGGVITVVAIAIVVPLSVTLSVKQMEQTSINNTSAASINNTSAASINNTSAACPSNWTEYGNKCFYFSEYTSNWTFSKDFCAAQGAELARFDTEEELNFLKRYKGSSGYWIGLHRESSEHPWKWTDNTQYNNLIPIRGDGQCGFLSDQLNISSSRVYVERPWICSKPKKYISQSQ" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/134308", "id": "134308", "database": "MGI" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "gene_name": "Clec2d3", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q5M9I1-1", "protein_name": "C-type lectin domain family 2 member D-related protein", "sequence": { "length": 235, "sequence": "MPSSAHLQDPPPHLSRTLTQDEEQTSLRQSSSCGPSTTSASASESLSGSTKSRISQKKLLEGMLPKIIPTESAAKLLCCYAVFMALTVVVIALSIALSVKKTPQISAVNTYAACQRNWIGFGNKCYYFNETARNWTFSQTLCKEQEAELARFDNEEELNFLKRYKGSSGYWIGLHRESSADPWKWTDNTAYNNLVPIKGEEKHGFLSDNGLSSGKDYIKRKSICSKLNSYTSQCP" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/134308", "id": "134308", "database": "MGI" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "gene_name": "", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q925N7-1", "protein_name": "C-type lectin domain family 2 member D5", "sequence": { "length": 233, "sequence": "MPSSAHLQDPPPLLSRTLTQNEGQTSLRQSSSCGPSAASASESLSGSTESRIPHSKMLQGKLPRNIPLEYPAGLYCCYVVIIVLSVAVVALSVALSVKKTAQISTINTYAACPRNWIGVGNKCFYFNEIPSNWTLSQTLCKEQGAELARFDTEEELNFLRRYKGSSGYWFGLHRESSAHPWKWTDNTEYNNSVSIGGDEKHGFLSDNGFSSGRGYIVRKSICRKPNSYTSQCL" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/134308", "id": "134308", "database": "MGI" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "gene_name": "Ocil", "tax_id": 10116 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078873.1", "ac": "NP_001078873.1", "name": "C-type lectin domain family 2 member D6", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046703", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8", "id": "A4KWA8", "database": "UniProtKB" } ], "name": "natural killer cell lectin-like receptor binding", "id": "GO:0046703" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8", "id": "A4KWA8", "database": "UniProtKB" } ], "name": "carbohydrate binding", "id": "GO:0030246" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8", "id": "A4KWA8", "database": "UniProtKB" } ], "name": "external side of plasma membrane", "id": "GO:0009897" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8", "id": "A4KWA8", "database": "UniProtKB" } ], "name": "integral component of membrane", "id": "GO:0016021" } ], "total": 2, "name": "Cellular Component" } ] }, "site_annotation": [ { "end_pos": 129, "annotation": "n_glycosylation_sequon", "start_pos": 127 }, { "end_pos": 134, "annotation": "n_glycosylation_sequon", "start_pos": 132 }, { "end_pos": 182, "annotation": "n_glycosylation_sequon", "start_pos": 180 } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000007866", "id": "ENSRNOG00000007866", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03593", "id": "cd03593", "database": "CDD" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/689790", "id": "689790", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "id": "IPR001304", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "id": "IPR016186", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "id": "IPR016187", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR033992", "id": "IPR033992", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:689790", "id": "rno:689790", "database": "KEGG Pathway" }, { "url": "https://omabrowser.org/oma/group/NEQEMAF/", "id": "NEQEMAF", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=945977at2759", "id": "945977at2759", "database": "OrthoDB" }, { "url": "http://pfam.xfam.org/family/PF00059", "id": "PF00059", "database": "Pfam" }, { "url": "http://purl.obolibrary.org/obo/PR_PR_A4KWA8", "id": "PR_A4KWA8", "database": "PRO" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078873", "id": "NP_001078873", "database": "RefSeq" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078873.1", "id": "NP_001078873.1", "database": "RefSeq" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1588698", "id": "1588698", "database": "RGD" }, { "url": "https://www.uniprot.org/uniprot/A0A0G2JWN5", "id": "A0A0G2JWN5", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/A0A0G2JWN5-1", "id": "A0A0G2JWN5-1", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/A4KWA8", "id": "A4KWA8", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/A4KWA8-1", "id": "A4KWA8-1", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [ { "comment": "N-linked (GlcNAc...) asparagine", "site_category": "predicted", "end_pos": 132, "residue": "Asn", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8#ptm_processing", "id": "A4KWA8", "database": "UniProtKB" } ], "subtype": "", "relation": "attached", "start_pos": 132, "glytoucan_ac": "", "type": "N-linked" } ], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 25877.0, "chemical_mass": 25877.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8", "name": "Clec2d6", "locus": {} } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A4KWA8#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "C-type lectin domain family 2 member D-like 1" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A4KWA8", "type": "synonym", "resource": "RefSeq", "name": "C-type lectin domain family 2 member D6" }, { "url": "https://www.uniprot.org/uniprot/A4KWA8#names_and_taxonomy", "type": "recommended", "resource": "UniProtKB", "name": "C-type lectin domain family 2 member D6" } ] }