{
    "uniprot_canonical_ac": "A4GG66-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A4GG66-1|CXG1_RAT Isoform 1 of Gap junction gamma-1 protein  OS=Rattus norvegicus OX=10116 GN=Gjc1 PE=2 SV=1 CANONICAL=A4GG66-1", 
        "length": 396, 
        "sequence": "MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDHEEDPMMYPEMELESEKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELDDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANIAQEQQYGSHEEHLPADLETLQREIRMAQERLDLAIQAYHHQNNPHGPREKKAKVGSKSGSNKSSISSKSGDGKTSVWI"
    }, 
    "uniprot_id": "CXG1_RAT", 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A4GG66", 
                    "id": "A4GG66", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "reaction_enzymes": [], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/10976050", 
                    "type": "PubMed", 
                    "id": "10976050"
                }
            ], 
            "title": "Defective vascular development in connexin 45-deficient mice.", 
            "journal": "Development (Cambridge, England)", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Kruger O, Plum A, Kim JS, Winterhager E, Maxeiner S, Hallas G, Kirchhoff S, Traub O, Lamers WH, Willecke K", 
            "date": "2000"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/11668048", 
                    "type": "PubMed", 
                    "id": "11668048"
                }
            ], 
            "title": "Connexin45 gap junction channels in rat cerebral vascular smooth muscle cells.", 
            "journal": "American journal of physiology. Heart and circulatory physiology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Li X, Simard JM", 
            "date": "2001"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/11922902", 
                    "type": "PubMed", 
                    "id": "11922902"
                }
            ], 
            "title": "Redistribution of connexin45 in gap junctions of connexin43-deficient hearts.", 
            "journal": "Cardiovascular research", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Johnson CM, Kanter EM, Green KG, Laing JG, Betsuyaku T, Beyer EC, Steinberg TH, Saffitz JE, Yamada KA", 
            "date": "2002"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/12064590", 
                    "type": "PubMed", 
                    "id": "12064590"
                }
            ], 
            "title": "Connexin45 interacts with zonula occludens-1 in osteoblastic cells.", 
            "journal": "Cell communication & adhesion", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Laing JG, Manley-Markowski RN, Koval M, Civitelli R, Steinberg TH", 
            "date": "2001"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/17328669", 
                    "type": "PubMed", 
                    "id": "17328669"
                }
            ], 
            "title": "Primary structure, organization, and expression of the rat connexin45 gene.", 
            "journal": "DNA Cell Biol.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A4GG66", 
                    "id": "A4GG66", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Vos M.A., Bierhuizen M.F., Jansen A.T., Mutsaers N.A., Teunissen B.E., Vuerhard M.J.", 
            "date": "2007"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/22982984", 
                    "type": "PubMed", 
                    "id": "22982984"
                }
            ], 
            "title": "Connexin45 provides optimal atrioventricular nodal conduction in the adult mouse heart.", 
            "journal": "Circulation research", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Frank M, Wirth A, Andrie RP, Kreuzberg MM, Dobrowolski R, Seifert G, Offermanns S, Nickenig G, Willecke K, Schrickel JW", 
            "date": "2012"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/24043768", 
                    "type": "PubMed", 
                    "id": "24043768"
                }
            ], 
            "title": "De novo expression of connexin hemichannels in denervated fast skeletal muscles leads to atrophy.", 
            "journal": "Proceedings of the National Academy of Sciences of the United States of America", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Cea LA, Cisterna BA, Puebla C, Frank M, Figueroa XF, Cardozo C, Willecke K, Latorre R, Saez JC", 
            "date": "2013"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/24883012", 
                    "type": "PubMed", 
                    "id": "24883012"
                }
            ], 
            "title": "Gap junction proteins in the light-damaged albino rat.", 
            "journal": "Molecular vision", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Guo CX, Tran H, Green CR, Danesh-Meyer HV, Acosta ML", 
            "date": "2014"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/27913256", 
                    "type": "PubMed", 
                    "id": "27913256"
                }
            ], 
            "title": "Rapid upregulation of the hippocampal connexins 36 and 45 mRNA levels during memory consolidation.", 
            "journal": "Behavioural brain research", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Beheshti S, Zeinali R, Esmaeili A", 
            "date": "2017"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/28561933", 
                    "type": "PubMed", 
                    "id": "28561933"
                }
            ], 
            "title": "Cx36, Cx43 and Cx45 in mouse and rat cerebellar cortex: species-specific expression, compensation in Cx36 null mice and co-localization in neurons vs. glia.", 
            "journal": "The European journal of neuroscience", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Nagy JI, Rash JE", 
            "date": "2017"
        }
    ], 
    "uniprot_ac": "A4GG66", 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A4GG66", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Cx45; Cxnq; Gja7"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A4GG66", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Gja7"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A4GG66", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Gjc1"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A4GG66", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Gjc1"
        }
    ], 
    "reactions": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A4GG66#A4GG66-1", 
            "isoform_ac": "A4GG66-1", 
            "locus": {
                "end_pos": 90781677, 
                "strand": "+", 
                "start_pos": 90782864, 
                "chromosome": "10", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000093570", 
                        "id": "ENSRNOT00000093570", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000076255", 
                        "id": "ENSRNOP00000076255", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A4GG66-1|CXG1_RAT Isoform 1 of Gap junction gamma-1 protein  OS=Rattus norvegicus OX=10116 GN=Gjc1 PE=2 SV=1 CANONICAL=A4GG66-1", 
                "length": 396, 
                "sequence": "MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDHEEDPMMYPEMELESEKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELDDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANIAQEQQYGSHEEHLPADLETLQREIRMAQERLDLAIQAYHHQNNPHGPREKKAKVGSKSGSNKSSISSKSGDGKTSVWI"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:266706", 
            "resource": "KEGG Pathway", 
            "id": "rno:266706", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-112303", 
            "description": "Electric Transmission Across Gap Junctions", 
            "resource": "Reactome", 
            "id": "R-RNO-112303", 
            "name": "Electric Transmission Across Gap Junctions"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-190861", 
            "description": "Gap junction assembly", 
            "resource": "Reactome", 
            "id": "R-RNO-190861", 
            "name": "Gap junction assembly"
        }
    ], 
    "reaction_participants": [], 
    "function": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
            "annotation": "Changes in connexins, including Cx36, Cx43, and Cx45, may contribute to the damage process. Publication Status: Online-Only", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
            "annotation": "Cx45-puncta in the cerebellar molecular layer were co-localized with Cx36-puncta and additionally occurred along Bergmann glial processes adjacent to Cx43-puncta. Expression of both Cx43 and Cx45 in Bergmann glia of rat may contribute to the complex properties of junctional coupling between these cells and perhaps to their reported coupling with Purkinje cells.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
            "annotation": "Data suggests that connexin 45 and ZO-1 directly interact in osteoblastic cells (ROS/Cx45) [ZO-1]", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A4GG66#function", 
            "annotation": "One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A4GG66#function", 
                    "id": "A4GG66", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
            "annotation": "The absence of Cx43/Cx45 hemichannels in skeltal muscles cells greatly attenuates the inflammasome activation and muscle atrophy.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
            "annotation": "The results of the present study revealed that during memory consolidation in a passive avoidance paradigm, a rapid upregulation of Cx45 mRNAs level occurs in the hippocampus, which declines to the control level by 24 h after training.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
                    "id": "NP_001078850.1", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "P28229-1", 
            "protein_name": "Gap junction gamma-1 protein", 
            "sequence": {
                "length": 396, 
                "sequence": "MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDHEEDPMMYPEMELESEKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELDDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANIAQEQQYGSHEEHLPADLETLQREIRMAQERLDLAIQAYHHQNNPHGPREKKAKVGSKSGSNKSSISSKSGDGKTSVWI"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/4016", 
                    "id": "4016", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Gjc1", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "P36383-1", 
            "protein_name": "Connexin-45", 
            "sequence": {
                "length": 396, 
                "sequence": "MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSHQNNPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVWI"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/4016", 
                    "id": "4016", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "GJC1", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
        "ac": "NP_001078850.1", 
        "name": "gap junction gamma-1 protein", 
        "summary": "component of gap junctions; involved in intercellular communication in arterial smooth muscle [RGD, Feb 2006]."
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005243", 
                        "pmid": "11668048", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "gap junction channel activity", 
                        "id": "GO:0005243"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005216", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ion channel activity", 
                        "id": "GO:0005216"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086077", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling", 
                        "id": "GO:0086077"
                    }
                ], 
                "total": 3, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005921", 
                        "pmid": "11668048", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "gap junction", 
                        "id": "GO:0005921"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "synapse", 
                        "id": "GO:0045202"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005922", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "connexin complex", 
                        "id": "GO:0005922"
                    }
                ], 
                "total": 4, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", 
                        "pmid": "11668048", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cell-cell signaling", 
                        "id": "GO:0007267"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001570", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "vasculogenesis", 
                        "id": "GO:0001570"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "heart development", 
                        "id": "GO:0007507"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "chemical synaptic transmission", 
                        "id": "GO:0007268"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "visual perception", 
                        "id": "GO:0007601"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048738", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cardiac muscle tissue development", 
                        "id": "GO:0048738"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048468", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cell development", 
                        "id": "GO:0048468"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086053", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "AV node cell to bundle of His cell communication by electrical coupling", 
                        "id": "GO:0086053"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016264", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A4GG66", 
                                "id": "A4GG66", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "gap junction assembly", 
                        "id": "GO:0016264"
                    }
                ], 
                "total": 9, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 17, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 15
        }, 
        {
            "end_pos": 381, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 379
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000048838", 
            "id": "ENSRNOG00000048838", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/266706", 
            "id": "266706", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000500", 
            "id": "IPR000500", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002265", 
            "id": "IPR002265", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013092", 
            "id": "IPR013092", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017990", 
            "id": "IPR017990", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019570", 
            "id": "IPR019570", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038359", 
            "id": "IPR038359", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:266706", 
            "id": "rno:266706", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/IMYGVSC/", 
            "id": "IMYGVSC", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=692491at2759", 
            "id": "692491at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11984", 
            "id": "PTHR11984", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00029", 
            "id": "PF00029", 
            "database": "Pfam"
        }, 
        {
            "url": "http://purl.obolibrary.org/obo/PR_PR_A4GG66", 
            "id": "PR_A4GG66", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-112303", 
            "id": "R-RNO-112303", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-190861", 
            "id": "R-RNO-190861", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850", 
            "id": "NP_001078850", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001078850.1", 
            "id": "NP_001078850.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=628889", 
            "id": "628889", 
            "database": "RGD"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A4GG66", 
            "id": "A4GG66", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A4GG66-1", 
            "id": "A4GG66-1", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 45666.0, 
        "chemical_mass": 45666.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A4GG66", 
            "name": "Gjc1", 
            "locus": {
                "end_pos": 90781402, 
                "strand": "-", 
                "start_pos": 90912287, 
                "chromosome": "10", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000048838", 
                        "id": "ENSRNOG00000048838", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A4GG66#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Connexin-45"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A4GG66#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Cx45"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A4GG66#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Gap junction alpha-7 protein"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A4GG66#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Gap junction gamma-1 protein"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A4GG66", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "gap junction gamma-1 protein"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A4GG66", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "gap junction membrane channel protein alpha 7; gap junction channel protein connexin 45; connexin-45; gap junction alpha-7 protein; connexin q"
        }
    ]
}