{ "uniprot_canonical_ac": "A2ACQ1-1", "ptm_annotation": [], "sequence": { "header": "tr|A2ACQ1-1|A2ACQ1_MOUSE Isoform 1 of RNA helicase OS=Mus musculus OX=10090 GN=Dhx35 PE=1 SV=1 CANONICAL=A2ACQ1-1", "length": 703, "sequence": "MAAPLGPVKFWKPGTEGPGVSISEERQSVTENSGTTIIYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTSVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTEEAFDQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVRDQLKKLLVKFQVPKVSSEGDPDPVLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDQ" }, "uniprot_id": "A2ACQ1_MOUSE", "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2ACQ1", "id": "A2ACQ1", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "reaction_enzymes": [ { "gene_name": "Dhx35", "uniprot_ac": "A0A0G2JTM6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JTM6", "id": "A0A0G2JTM6", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JTM6", "id": "A0A0G2JTM6", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Chd9", "uniprot_ac": "A0A0G2JXQ2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JXQ2", "id": "A0A0G2JXQ2", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JXQ2", "id": "A0A0G2JXQ2", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Mcm5", "uniprot_ac": "A0A0G2JY07", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JY07", "id": "A0A0G2JY07", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JY07", "id": "A0A0G2JY07", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "RGD1564855", "uniprot_ac": "A0A0G2K0H9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0H9", "id": "A0A0G2K0H9", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0H9", "id": "A0A0G2K0H9", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Dhx8", "uniprot_ac": "A0A0G2K283", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K283", "id": "A0A0G2K283", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K283", "id": "A0A0G2K283", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Chd2", "uniprot_ac": "A0A0G2KA92", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "id": "A0A0G2KA92", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA92", "id": "A0A0G2KA92", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Dhx8", "uniprot_ac": "A2A4P0", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A4P0", "id": "A2A4P0", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A4P0", "id": "A2A4P0", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Chd5", "uniprot_ac": "A2A8L1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A8L1", "id": "A2A8L1", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A8L1", "id": "A2A8L1", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Dhx35", "uniprot_ac": "A2ACQ1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2ACQ1", "id": "A2ACQ1", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2ACQ1", "id": "A2ACQ1", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Chd7", "uniprot_ac": "A2AJK6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AJK6", "id": "A2AJK6", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AJK6", "id": "A2AJK6", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "HFM1", "uniprot_ac": "A2PYH4", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2PYH4", "id": "A2PYH4", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2PYH4", "id": "A2PYH4", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Chd6", "uniprot_ac": "A3KFM7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KFM7", "id": "A3KFM7", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A3KFM7", "id": "A3KFM7", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "SMCHD1", "uniprot_ac": "A6NHR9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6NHR9", "id": "A6NHR9", "database": "UniProtKB" } ], "ec_number": "3.6.1.-", "activity": "" } ] }, { "gene_name": "DDX11L8", "uniprot_ac": "A8MPP1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A8MPP1", "id": "A8MPP1", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A8MPP1", "id": "A8MPP1", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Chd3", "uniprot_ac": "B1AR17", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/B1AR17", "id": "B1AR17", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/B1AR17", "id": "B1AR17", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Ythdc2", "uniprot_ac": "B2RR83", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/B2RR83", "id": "B2RR83", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/B2RR83", "id": "B2RR83", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Ddx41", "uniprot_ac": "B2RYL8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/B2RYL8", "id": "B2RYL8", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/B2RYL8", "id": "B2RYL8", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Hfm1", "uniprot_ac": "D3Z4R1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3Z4R1", "id": "D3Z4R1", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3Z4R1", "id": "D3Z4R1", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Smarcad1", "uniprot_ac": "D3Z9Z9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3Z9Z9", "id": "D3Z9Z9", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3Z9Z9", "id": "D3Z9Z9", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Chd6", "uniprot_ac": "D3ZA12", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZA12", "id": "D3ZA12", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZA12", "id": "D3ZA12", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Chd7", "uniprot_ac": "D3ZAP7", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZAP7", "id": "D3ZAP7", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZAP7", "id": "D3ZAP7", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Chd5", "uniprot_ac": "D3ZD32", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZD32", "id": "D3ZD32", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZD32", "id": "D3ZD32", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Dhx58", "uniprot_ac": "D3ZD46", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZD46", "id": "D3ZD46", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZD46", "id": "D3ZD46", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Dhx15", "uniprot_ac": "D3ZD97", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZD97", "id": "D3ZD97", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZD97", "id": "D3ZD97", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Ercc2", "uniprot_ac": "D3ZEG9", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZEG9", "id": "D3ZEG9", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZEG9", "id": "D3ZEG9", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Mcm3", "uniprot_ac": "D3ZFP4", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZFP4", "id": "D3ZFP4", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZFP4", "id": "D3ZFP4", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Dna2", "uniprot_ac": "D3ZG52", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZG52", "id": "D3ZG52", "database": "UniProtKB" } ], "ec_number": "3.1.-.-", "activity": "" }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZG52", "id": "D3ZG52", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." } ] }, { "gene_name": "Dhx29", "uniprot_ac": "D3ZHW0", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZHW0", "id": "D3ZHW0", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZHW0", "id": "D3ZHW0", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Ddx54", "uniprot_ac": "D3ZHY6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZHY6", "id": "D3ZHY6", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZHY6", "id": "D3ZHY6", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Ythdc2", "uniprot_ac": "D3ZIV8", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZIV8", "id": "D3ZIV8", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZIV8", "id": "D3ZIV8", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Mcm2", "uniprot_ac": "D3ZP96", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZP96", "id": "D3ZP96", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZP96", "id": "D3ZP96", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Blm", "uniprot_ac": "D3ZQW1", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZQW1", "id": "D3ZQW1", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZQW1", "id": "D3ZQW1", "database": "UniProtKB" } ], "ec_number": "3.6.4.12", "activity": "" } ] }, { "gene_name": "Dhx33", "uniprot_ac": "D3ZSV6", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZSV6", "id": "D3ZSV6", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZSV6", "id": "D3ZSV6", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] }, { "gene_name": "Mov10", "uniprot_ac": "D3ZUC2", "activity": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZUC2", "id": "D3ZUC2", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/D3ZUC2", "id": "D3ZUC2", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", 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"ec_number": "3.6.4.13", "activity": "ATP + H(2)O = ADP + phosphate." }, { "evidence": [ { "url": "https://www.uniprot.org/uniprot/Q9Z1N5", "id": "Q9Z1N5", "database": "UniProtKB" } ], "ec_number": "3.6.4.13", "activity": "" } ] } ], "publication": [], "uniprot_ac": "A2ACQ1", "gene_names": [ { "url": "https://www.uniprot.org/uniprot/A2ACQ1", "type": "recommended", "resource": "UniProtKB", "name": "Dhx35" } ], "reactions": [ { "output_participant_list": [], "evidence": [ { "url": "https://www.rhea-db.org/rhea/13065", "id": "13065", "database": "Rhea" } ], "name": "", "cellular_location": "plasma membrane", "equation": "ATP + H2O = ADP + H(+) + phosphate", "input_participant_list": [], "enzyme_list": [ "F1M9L4-1", "F1MA70-1", "D3ZHW0-1", "D3ZHY6-1", "A0A0G2JXQ2-1", "Q6AYI1-1", "A0A0G2KA92-1", "D4A9D6-1", "Q9QUL6-1", "D4A321-1", "Q5BJS0-1", "D3ZIV8-1", "D3ZAP7-1", "Q6MG13-1", "F1LTH9-1", "D4A5W5-1", "G3V6W5-1", "G3V681-1", "F1LNJ2-1", "P46462-1", "A0A0G2JY07-1", "Q4KLL7-1", "D3ZA12-1", 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"P19447-1", "Q14566-1", "P33993-1", "Q8NDG6-1", "Q587J7-1", "O14656-1", "Q92698-1", "Q14839-1", "Q4VNC0-1", "Q9H7F0-1", "Q9UMR2-1", "O75351-1", "O94762-1", "Q9H5Z1-1", "P18074-1", "P51530-1", "Q9Y265-1", "P33992-1", "Q8TDD1-1", "Q7Z478-1", "P49736-1", "Q8NG08-1", "Q4VNC1-1", "O95786-1", "Q9HCE1-1", "Q8TD26-1", "Q12873-1", "Q8IY21-1", "Q9Y4B4-1", "Q9HD20-1", "O14646-1", "O14647-1", "O43143-1", "Q14147-1", "Q6P158-1", "Q8IX18-1", "Q92771-1", "Q9Y2R4-1", "Q9NVP1-1", "Q9UHL0-1", "O15523-1", "O60231-1", "Q14562-1", "Q7L7V1-1", "Q86TM3-1", "Q96C10-1", "Q9GZR7-1", "Q9H6R0-1", "Q9NUL7-1", "Q9UHI6-1", "Q9Y6V7-1", "Q5T1V6-1", "Q7L2E3-1", "Q8NHQ9-1", "P17844-1", "Q7L014-1", "Q8N8A6-1", "Q9H0S4-1", "Q6PIW4-1", "Q9BX63-1", "Q13283-1", "Q9BYX4-1", "Q9NXL9-1", "Q9UJA3-1", "Q8IVL1-1", "P46459-1", "Q9H611-1", "Q92620-1", "Q9NZ71-1", "Q8IYB8-1", "P13984-1", "O60306-1", "Q8N3C0-1", "A8MPP1-1", "Q92841-4", "Q2NKX8-1", "Q8IYD8-1", "P11021-1", "A2PYH4-1", "P60842-1", "Q14240-1", "Q9BXT6-1", "P25205-1", "O94761-1", "Q9H4L7-1", "Q8NB90-1", "P38935-1", "P55072-1", "Q14191-1", "Q8TE96-1", "Q9NR30-1", "Q13838-1", "Q8TDG4-1", "P38919-1", "Q96RR1-1", "P46063-1", "A6NHR9-1", "O75643-1", "Q9UN37-1", "Q9H6S0-1", "P42285-1", "P54132-1", "Q9H2U1-1", "Q08211-1", "Q96FC9-1", "Q8NFZ0-1", "Q9ULG1-1", "O14657-1", "P26196-1", "O00571-1", "Q9H8K7-1", "Q8IY37-1", "Q92499-1", "Q8NBU5-1", "Q6PL18-1", "Q96S55-1", "Q9H078-1", "Q9Y6X9-1", "Q8BGE5-1", "Q99NG0-1", "O88700-1", "A2A4P0-1", "Q62095-1", "Q99PU8-1", "O35286-1", "Q6PGC1-1", "Q9Z1N5-1", "Q8BHK9-1", "Q8VDW0-1", "P10630-1", "Q8R5F7-1", "Q2KHI9-1", "P97310-1", "P23249-1", "P46460-1", "Q04692-1", "Q9CWU0-1", "Q9ER39-1", "Q9ER41-1", "Q9WTM5-1", "P70270-1", "Q62167-1", "Q61655-1", "P54823-1", "Q5XF90-1", "Q3TYU2-1", "A2ACQ1-1", "A3KFM7-1", "Q6PDQ2-1", "O08811-1", "Q75NR7-1", "Q9Z129-1", "Q61881-1", "B1AR17-1", "O09053-1", "Q8BYH8-1", "G3X8X0-1", "P49717-1", "Q9D5T0-1", "Q60649-1", "A2AJK6-1", "Q9CWX9-1", "Q6PE54-1", "A2A8L1-1", "E9PZM4-1", "Q9CXF7-1", "Q61656-1", "Q6ZPL9-1", "Q8K363-1", "P16381-1", "Q4FZF3-1", "Q501J6-1", "Q8K301-1", "Q8VHK9-1", "Q921N6-1", "Q9CWT6-1", "Q9D0R4-1", "Q9DBV3-1", "Q61496-1", "Q6AXC6-1", "Q6P9R1-1", "Q80VY9-1", "Q80Y44-1", "Q99MJ9-1", "Q9JJY4-1", "Q9QY15-1", "P49135-1", "Q8BPY9-1", "Q8K2I9-1", "Q2VPA6-1", "Q6ZPV2-1", "P49718-1", "P97311-1", "Q99MV5-1", "Q8VID5-1", "P60122-1", "Q80YD1-1", "Q8CFQ3-1", "Q61687-1", "Q09XV5-1", "Q569Z5-1", "Q810A7-1", "Q9DBN9-1", "Q6P5D3-1", "Q6Q899-1", "Q8K4L0-1", "Q6ZQJ5-1", "Q99J87-1", "Q6NZQ2-1", "Q8BZS9-1", "Q91VN6-1", "Q91VR5-1", "Q9ESV0-1", "P20029-1", "Q91VC3-1", "Q8CIW5-1", "Q80SX8-1", "Q0VGM9-1", "Q3UMC0-1", "P40694-1", "E9PZJ8-1", "Q5XF89-1", "Q9EPE9-1", "P40201-1", "Q924H9-1", "Q5SXJ3-1", "Q6NVF4-1", "D3Z4R1-1", "P60843-1", "P25206-1", "Q01853-1", "Q8R0A0-1", "Q14BI7-1", "O70133-1", "P97855-1", "Q6P5D8-1", "Q6P4T2-1", "P46467-1", "Q8VEJ9-1", "B2RR83-1", "Q9JIK5-1", "Q9CWV1-1", "Q9CZU3-1", "Q9D2Q3-1", "Q69ZX6-1", "Q9WV86-1", "Q8CDM1-1", "Q80X98-1", "Q8C5W4-1", "Q91XU0-1" ], "id": "13065", "summary": "" } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2ACQ1#A2ACP9-1", "isoform_ac": "A2ACP9-1", "locus": { "end_pos": 158794889, "strand": "-", "start_pos": 158829586, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000156893", "id": "ENSMUST00000156893", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000119497", "id": "ENSMUSP00000119497", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A2ACP9-1|A2ACQ1_MOUSE Computationally mapped isoform of RNA helicase OS=Mus musculus OX=10090 GN=Dhx35 PE=1 SV=1 CANONICAL=A2ACQ1-1", "length": 213, "sequence": "MAAPLGPVKFWKPGTEGPGVSISEERQSVTENSGTTIIYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTKFRDFFNQNETSDPARDTSVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRV" } }, { "url": "https://www.uniprot.org/uniprot/A2ACQ1#A2ACQ1-1", "isoform_ac": "A2ACQ1-1", "locus": { "end_pos": 158794889, "strand": "-", "start_pos": 158857121, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000109478", "id": "ENSMUST00000109478", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000105104", "id": "ENSMUSP00000105104", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A2ACQ1-1|A2ACQ1_MOUSE Isoform 1 of RNA helicase OS=Mus musculus OX=10090 GN=Dhx35 PE=1 SV=1 CANONICAL=A2ACQ1-1", "length": 703, "sequence": "MAAPLGPVKFWKPGTEGPGVSISEERQSVTENSGTTIIYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTSVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTEEAFDQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVRDQLKKLLVKFQVPKVSSEGDPDPVLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDQ" } }, { "url": "https://www.uniprot.org/uniprot/A2ACQ1#Q8K1G9-1", "isoform_ac": "Q8K1G9-1", "locus": { "end_pos": 158794889, "strand": "-", "start_pos": 158857121, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000029186", "id": "ENSMUST00000029186", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000029186", "id": "ENSMUSP00000029186", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|Q8K1G9-1|A2ACQ1_MOUSE Computationally mapped isoform of RNA helicase OS=Mus musculus OX=10090 GN=Dhx35 PE=1 SV=1 CANONICAL=A2ACQ1-1", "length": 679, "sequence": "MAAPLGPVKFWKPGTEGPGVSISEERQSVTENSGTTIIYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTSVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTEEAFDQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVRDQLKKLLVKFQVPKVSSEGDPDPVLRCIVSGFFANAARFHSSGAYRVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDQ" } } ], "pathway": [], "reaction_participants": [], "function": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTM6-1", "protein_name": "RNA helicase", "sequence": { "length": 703, "sequence": "MAAPLGPVKFWKPGTEGPGVSISEERQSVTENSGTTVIYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTVVIVGETGCGKSTQVPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVVMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTEEAFEQLPQSTVPEMQRSNLAPVVLQLKALGIDSVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVRDQLKKLLVKFQVPKMSSEGDPDPVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDQ" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A2ACQ1/", "id": "A2ACQ1", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/6406", "id": "6406", "database": "MGI" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "gene_name": "Dhx35", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q9H5Z1-1", "protein_name": "Probable ATP-dependent RNA helicase DHX35", "sequence": { "length": 703, "sequence": "MAAPVGPVKFWRPGTEGPGVSISEERQSLAENSGTTVVYNPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSEGDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDP" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A2ACQ1/", "id": "A2ACQ1", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/6406", "id": "6406", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "DHX35", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_665685.1", "ac": "NP_665685.1", "name": "probable ATP-dependent RNA helicase DHX35 isoform a", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2ACQ1", "id": "A2ACQ1", "database": "UniProtKB" } ], "name": "RNA binding", "id": "GO:0003723" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2ACQ1", "id": "A2ACQ1", "database": "UniProtKB" } ], "name": "ATP binding", "id": "GO:0005524" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2ACQ1", "id": "A2ACQ1", "database": "UniProtKB" } ], "name": "RNA helicase activity", "id": "GO:0003724" } ], "total": 3, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2ACQ1", "id": "A2ACQ1", "database": "UniProtKB" } ], "name": "catalytic step 2 spliceosome", "id": "GO:0071013" } ], "total": 1, "name": "Cellular Component" } ] }, "site_annotation": [ { "end_pos": 225, "annotation": "n_glycosylation_sequon", "start_pos": 223 }, { "end_pos": 399, "annotation": "n_glycosylation_sequon", "start_pos": 397 }, { "end_pos": 561, "annotation": "n_glycosylation_sequon", "start_pos": 559 } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000027655", "id": "ENSMUSG00000027655", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/71715", "id": "71715", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "id": "IPR001650", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR002464", "id": "IPR002464", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR007502", "id": "IPR007502", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR011709", "id": "IPR011709", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "id": "IPR014001", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "id": "IPR027417", "database": "InterPro" }, { "url": "http://www.informatics.jax.org/marker/MGI:1918965", "id": "1918965", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/LCKCITA/", "id": "LCKCITA", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=354219at2759", "id": "354219at2759", "database": "OrthoDB" }, { "url": "http://pfam.xfam.org/family/PF00271", "id": "PF00271", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF04408", "id": "PF04408", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF07717", "id": "PF07717", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_665685", "id": "NP_665685", "database": "RefSeq" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_665685.1", "id": "NP_665685.1", "database": "RefSeq" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006500251", "id": "XP_006500251", "database": "RefSeq" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006500251.1", "id": "XP_006500251.1", "database": "RefSeq" }, { "url": "https://www.rhea-db.org/rhea/13065", "id": "13065", "database": "Rhea" }, { "url": "https://www.uniprot.org/uniprot/A2ACP9", "id": "A2ACP9", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/A2ACP9-1", "id": "A2ACP9-1", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/A2ACQ1", "id": "A2ACQ1", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/A2ACQ1-1", "id": "A2ACQ1-1", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/Q8K1G9", "id": "Q8K1G9", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/Q8K1G9-1", "id": "Q8K1G9-1", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 78740.0, "chemical_mass": 78740.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A2ACQ1", "name": "Dhx35", "locus": { "end_pos": 158858214, "strand": "+", "start_pos": 158794807, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000027655", "id": "ENSMUSG00000027655", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A2ACQ1#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "3.6.4.13" }, { "url": "https://www.uniprot.org/uniprot/A2ACQ1#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "DEAH (Asp-Glu-Ala-His) box polypeptide 35" }, { "url": "https://www.uniprot.org/uniprot/A2ACQ1#names_and_taxonomy", "type": "recommended", "resource": "UniProtKB", "name": "RNA helicase" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2ACQ1", "type": "synonym", "resource": "RefSeq", "name": "probable ATP-dependent RNA helicase DHX35 isoform a" } ] }