{ "uniprot_canonical_ac": "A2A9R3-1", "ptm_annotation": [], "sequence": { "header": "sp|A2A9R3-1|MAGB4_MOUSE Isoform 1 of Melanoma-associated antigen B4 OS=Mus musculus OX=10090 GN=Mageb4 PE=1 SV=1 CANONICAL=A2A9R3-1", "length": 556, "sequence": "MPRGQKSKARAREKRRLVQDEAQELQDAQAKAGEKGKSPSCSNQDSGDAVASTSTAGFPQKSKSQGEAPTTTARKGGACRRSRKSTRGPREESTSCTRVPRFSENPQNDLLTRKTGMLMQYLLCKYKMKQPASKGEMLKVINRRFKEQLPEILKKASERIQLVFGLEVKEIKPNGGYYTLVSKLDPSVGNALTTSLPFPQNGLLMPLLGVIFLNGNRASEAEIWEFLNVLGIYDGKVHIIFGEPRKLITRDLVKEKYLVYQKEANSDPPSFEFLWGPRAYAETTKMKILEFLAEVNETVPQAFPTHYEEALRDQEERAQAEAVGSPGTSAKDKAEAKVTLVDSSCKYQAESKVTLVDSSCKDQAESKVTLVDPSCKDNAKSKVTLGSSRKYKAKSKVPLVDSSCKDQAESKVTLVDSCKDQAESKVTLVDSSCKDQAESKVTLVDSSCKDQAESKVTLVDPSCKDKAKSKVTLGSSHKYKAKSKVTLVDSSCKDQAESKVTLVDSSCKDQAESKVTLVDPSCKDNAKSKVTLGSSRKYKAKSKVPLVDSSGKDKAV" }, "uniprot_id": "MAGB4_MOUSE", "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A9R3", "id": "A2A9R3", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "reaction_enzymes": [], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/10706124", "type": "PubMed", "id": "10706124" } ], "title": "Mage-b4, a novel melanoma antigen (MAGE) gene specifically expressed during germ cell differentiation.", "journal": "Cancer Res.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A9R3", "id": "A2A9R3", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028664.2", "id": "NP_001028664.2", "database": "RefSeq" } ], "authors": "Nordqvist K., Toehoenen V., Forslund K.O., Osterlund C.", "date": "2000" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/11454705", "type": "PubMed", "id": "11454705" } ], "title": "An overview of the MAGE gene family with the identification of all human members of the family.", "journal": "Cancer research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028664.2", "id": "NP_001028664.2", "database": "RefSeq" } ], "authors": "Chomez P, De Backer O, Bertrand M, De Plaen E, Boon T, Lucas S", "date": "2001" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/15923608", "type": "PubMed", "id": "15923608" } ], "title": "Normal sexual development and fertility in testatin knockout mice.", "journal": "Molecular and cellular biology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028664.2", "id": "NP_001028664.2", "database": "RefSeq" } ], "authors": "Tohonen V, Frygelius J, Mohammadieh M, Kvist U, Pelliniemi LJ, O'Brien K, Nordqvist K, Wedell A", "date": "2005" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/21183079", "type": "PubMed", "id": "21183079" } ], "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "evidence": [ { "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2A9R3", "id": "A2A9R3", "database": "iPTMnet" } ], "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "date": "2010" } ], "uniprot_ac": "A2A9R3", "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2A9R3", "type": "synonym", "resource": "RefSeq", "name": "CN71689; CN716893; Mage-b; Mage-b4; mMage-b; mMage-b4" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2A9R3", "type": "synonym", "resource": "RefSeq", "name": "Mageb4" }, { "url": "https://www.uniprot.org/uniprot/A2A9R3", "type": "recommended", "resource": "UniProtKB", "name": "Mageb4" } ], "reactions": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2A9R3#A2A9R3-1", "isoform_ac": "A2A9R3-1", "locus": { "end_pos": 86250754, "strand": "+", "start_pos": 86252421, "chromosome": "X", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000113969", "id": "ENSMUST00000113969", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000109602", "id": "ENSMUSP00000109602", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2A9R3-1|MAGB4_MOUSE Isoform 1 of Melanoma-associated antigen B4 OS=Mus musculus OX=10090 GN=Mageb4 PE=1 SV=1 CANONICAL=A2A9R3-1", "length": 556, "sequence": "MPRGQKSKARAREKRRLVQDEAQELQDAQAKAGEKGKSPSCSNQDSGDAVASTSTAGFPQKSKSQGEAPTTTARKGGACRRSRKSTRGPREESTSCTRVPRFSENPQNDLLTRKTGMLMQYLLCKYKMKQPASKGEMLKVINRRFKEQLPEILKKASERIQLVFGLEVKEIKPNGGYYTLVSKLDPSVGNALTTSLPFPQNGLLMPLLGVIFLNGNRASEAEIWEFLNVLGIYDGKVHIIFGEPRKLITRDLVKEKYLVYQKEANSDPPSFEFLWGPRAYAETTKMKILEFLAEVNETVPQAFPTHYEEALRDQEERAQAEAVGSPGTSAKDKAEAKVTLVDSSCKYQAESKVTLVDSSCKDQAESKVTLVDPSCKDNAKSKVTLGSSRKYKAKSKVPLVDSSCKDQAESKVTLVDSCKDQAESKVTLVDSSCKDQAESKVTLVDSSCKDQAESKVTLVDPSCKDKAKSKVTLGSSHKYKAKSKVTLVDSSCKDQAESKVTLVDSSCKDQAESKVTLVDPSCKDNAKSKVTLGSSRKYKAKSKVPLVDSSGKDKAV" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:434903", "resource": "KEGG Pathway", "id": "mmu:434903", "name": "" } ], "reaction_participants": [], "function": [], "orthologs": [ { "uniprot_canonical_ac": "O15479-1", "protein_name": "Melanoma-associated antigen B2", "sequence": { "length": 319, "sequence": "MPRGQKSKLRAREKRRKARDETRGLNVPQVTEAEEEEAPCCSSSVSGGAASSSPAAGIPQEPQRAPTTAAAAAAGVSSTKSKKGAKSHQGEKNASSSQASTSTKSPSEDPLTRKSGSLVQFLLYKYKIKKSVTKGEMLKIVGKRFREHFPEILKKASEGLSVVFGLELNKVNPNGHTYTFIDKVDLTDEESLLSSWDFPRRKLLMPLLGVIFLNGNSATEEEIWEFLNMLGVYDGEEHSVFGEPWKLITKDLVQEKYLEYKQVPSSDPPRFQFLWGPRAYAETSKMKVLEFLAKVNGTTPCAFPTHYEEALKDEEKAGV" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/134515", "id": "134515", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "MAGEB2", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028664.2", "ac": "NP_001028664.2", "name": "melanoma-associated antigen B4", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "pmid": "10706124", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A9R3", "id": "A2A9R3", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" } ], "total": 1, "name": "Cellular Component" } ] }, "site_annotation": [ { "end_pos": 298, "annotation": "n_glycosylation_sequon", "start_pos": 296 } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000035427", "id": "ENSMUSG00000035427", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/434903", "id": "434903", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR002190", "id": "IPR002190", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR021072", "id": "IPR021072", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR037445", "id": "IPR037445", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR041898", "id": "IPR041898", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR041899", "id": "IPR041899", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:434903", "id": "mmu:434903", "database": "KEGG Pathway" }, { "url": "http://www.informatics.jax.org/marker/MGI:2148568", "id": "2148568", "database": "MGI" }, { "url": "http://www.orthodb.org/?query=1195799at2759", "id": "1195799at2759", "database": "OrthoDB" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736", "id": "PTHR11736", "database": "PANTHER" }, { "url": "http://pfam.xfam.org/family/PF01454", "id": "PF01454", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF12440", "id": "PF12440", "database": "Pfam" }, { "url": "http://purl.obolibrary.org/obo/PR_PR_A2A9R3", "id": "PR_A2A9R3", "database": "PRO" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028664", "id": "NP_001028664", "database": "RefSeq" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001028664.2", "id": "NP_001028664.2", "database": "RefSeq" }, { "url": "https://www.uniprot.org/uniprot/A2A9R3", "id": "A2A9R3", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/A2A9R3-1", "id": "A2A9R3-1", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [ { "residue": "Ser", "comment": "", "kinase_gene_name": "Atxn7l3b", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/21183079", "id": "21183079", "database": "PubMed" } ], "start_pos": 325, "end_pos": 325, "kinase_uniprot_canonical_ac": "Q3UD01-1" }, { "residue": "Ser", "comment": "Phosphoserine", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A9R3", "id": "A2A9R3", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/pubmed/21183079", "id": "21183079", "database": "PubMed" } ], "start_pos": 325, "end_pos": 325, "kinase_uniprot_canonical_ac": "" } ], "mass": { "monoisotopic_mass": 60922.0, "chemical_mass": 60922.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A2A9R3", "name": "Mageb4", "locus": { "end_pos": 86250254, "strand": "-", "start_pos": 86305093, "chromosome": "X", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000035427", "id": "ENSMUSG00000035427", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A2A9R3#names_and_taxonomy", "type": "recommended", "resource": "UniProtKB", "name": "Melanoma-associated antigen B4" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2A9R3", "type": "synonym", "resource": "RefSeq", "name": "melanoma antigen, family B, 4" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2A9R3", "type": "synonym", "resource": "RefSeq", "name": "melanoma-associated antigen B4" } ] }