{ "uniprot_canonical_ac": "A0PJY2-1", "ptm_annotation": [], "sequence": { "header": "sp|A0PJY2-1|FEZF1_HUMAN Isoform 1 of Fez family zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FEZF1 PE=1 SV=1 CANONICAL=A0PJY2-1", "length": 475, "sequence": "MDSSCHNATTKMLATAPARGNMMSTSKPLAFSIERIMARTPEPKALPVPHFLQGALPKGEPKHSLHLNSSIPCMIPFVPVAYDTSPKAGVTGSEPRKASLEAPAAPAAVPSAPAFSCSDLLNCALSLKGDLARDALPLQQYKLVRPRVVNHSSFHAMGALCYLNRGDGPCHPAAGVNIHPVASYFLSSPLHPQPKTYLAERNKLVVPAVEKYPSGVAFKDLSQAQLQHYMKESAQLLSEKIAFKTSDFSRGSPNAKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQVYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDSSLGLARTPAGEPGTEPPPPLPQQPPMTLPPLQPPLPTPGPLQPGLHQGHQ" }, "uniprot_id": "", "glycation": [], "keywords": [], "species": [ { "common_name": "Human", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0PJY2", "id": "A0PJY2", "database": "UniProtKB" } ], "name": "Homo sapiens", "taxid": 9606 } ], "reaction_enzymes": [], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/19318583", "type": "PubMed", "id": "19318583" } ], "title": "Human ZNF312b promotes the progression of gastric cancer by transcriptional activation of the K-ras gene.", "journal": "Cancer Res.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0PJY2", "id": "A0PJY2", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ], "authors": "Kim H.T., Kim J.M., Song I.S., Kim N.S., Yoo H.S., Jeong S.Y., Ha G.H., Kim C.H., Kim D.I., Oh N.S.", "date": "2009" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/19401682", "type": "PubMed", "id": "19401682" } ], "title": "High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.", "journal": "Molecular psychiatry", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ], "authors": "Maestrini E, Pagnamenta AT, Lamb JA, Bacchelli E, Sykes NH, Sousa I, Toma C, Barnby G, Butler H, Winchester L, Scerri TS, Minopoli F, Reichert J, Cai G, Buxbaum JD, Korvatska O, Schellenberg GD, Dawson G, de Bildt A, Minderaa RB, Mulder EJ, Morris AP, Bailey AJ, Monaco AP", "date": "2010" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/21170990", "type": "PubMed", "id": "21170990" } ], "title": "Human ZNF312b oncogene is regulated by Sp1 binding to its promoter region through DNA demethylation and histone acetylation in gastric cancer.", "journal": "International journal of cancer", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ], "authors": "Song IS, Ha GH, Kim JM, Jeong SY, Lee HC, Kim YS, Kim YJ, Kwon TK, Kim NS", "date": "2011" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/24913420", "type": "PubMed", "id": "24913420" } ], "title": "Fez family transcription factors: controlling neurogenesis and cell fate in the developing mammalian nervous system.", "journal": "BioEssays : news and reviews in molecular, cellular and developmental biology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ], "authors": "Eckler MJ, Chen B", "date": "2014" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/25192046", "type": "PubMed", "id": "25192046" } ], "title": "Mutations in FEZF1 cause Kallmann syndrome.", "journal": "Am. J. Hum. Genet.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0PJY2", "id": "A0PJY2", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ], "authors": "Topaloglu A.K., Kotan L.D., Yuksel B., Wray S., Bicakci Y.K., Cheng P.J., Demirel F., Esen I., Gurbuz F., Hutchins B.I., Mengen E., Ozkan Y., Stoner H.", "date": "2014" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/30416194", "type": "PubMed", "id": "30416194" } ], "title": "Long Noncoding RNA FEZF1-AS1 Promotes Proliferation and Inhibits Apoptosis in Ovarian Cancer by Activation of JAK-STAT3 Pathway.", "journal": "Medical science monitor : international medical journal of experimental and clinical research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ], "authors": "Zhao X, Cheng Z, Wang J", "date": "2018" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/31378890", "type": "PubMed", "id": "31378890" } ], "title": "Mechanism of lncRNA FEZF1-AS1 in promoting the occurrence and development of oral squamous cell carcinoma through targeting miR-196a.", "journal": "European review for medical and pharmacological sciences", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ], "authors": "Xu L, Hou TJ, Yang P", "date": "2019" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/31785996", "type": "PubMed", "id": "31785996" } ], "title": "Circulatinglong non-coding RNA FEZF1-AS1 and AFAP1-AS1 serve as potential diagnostic biomarkers for gastric cancer.", "journal": "Pathology, research and practice", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ], "authors": "Liu W, Li Y, Zhang Y, Shen X, Su Z, Chen L, Cai W, Wang F, Ju S", "date": "2020" } ], "uniprot_ac": "A0PJY2", "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A0PJY2", "type": "synonym", "resource": "RefSeq", "name": "FEZ; HH22; ZNF312B" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0PJY2", "type": "synonym", "resource": "RefSeq", "name": "FEZF1" }, { "url": "https://www.uniprot.org/uniprot/A0PJY2", "type": "recommended", "resource": "UniProtKB", "name": "FEZF1" }, { "url": "https://www.uniprot.org/uniprot/A0PJY2", "type": "synonym", "resource": "UniProtKB", "name": "FEZ" }, { "url": "https://www.uniprot.org/uniprot/A0PJY2", "type": "synonym", "resource": "UniProtKB", "name": "ZNF312B" } ], "reactions": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0PJY2#A0PJY2-1", "isoform_ac": "A0PJY2-1", "locus": { "end_pos": 122302000, "strand": "+", "start_pos": 122304437, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000442488", "id": "ENST00000442488", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000411145", "id": "ENSP00000411145", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A0PJY2-1|FEZF1_HUMAN Isoform 1 of Fez family zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FEZF1 PE=1 SV=1 CANONICAL=A0PJY2-1", "length": 475, "sequence": "MDSSCHNATTKMLATAPARGNMMSTSKPLAFSIERIMARTPEPKALPVPHFLQGALPKGEPKHSLHLNSSIPCMIPFVPVAYDTSPKAGVTGSEPRKASLEAPAAPAAVPSAPAFSCSDLLNCALSLKGDLARDALPLQQYKLVRPRVVNHSSFHAMGALCYLNRGDGPCHPAAGVNIHPVASYFLSSPLHPQPKTYLAERNKLVVPAVEKYPSGVAFKDLSQAQLQHYMKESAQLLSEKIAFKTSDFSRGSPNAKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQVYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDSSLGLARTPAGEPGTEPPPPLPQQPPMTLPPLQPPLPTPGPLQPGLHQGHQ" } }, { "url": "https://www.uniprot.org/uniprot/A0PJY2#A0PJY2-2", "isoform_ac": "A0PJY2-2", "locus": { "end_pos": 122302000, "strand": "+", "start_pos": 122304437, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000427185", "id": "ENST00000427185", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000392727", "id": "ENSP00000392727", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A0PJY2-2|FEZF1_HUMAN Isoform 2 of Fez family zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FEZF1 PE=1 SV=1 CANONICAL=A0PJY2-1", "length": 425, "sequence": "MDSSCHNATTKMLATAPARGNMMSTSKPLAFSIERIMARTPEPKALPVPHFLQGALPKGEPKHSLHLNSSIPCMIPFVPVAYDTSPKAGVTGSEPRKASLEAPAAPAAVPSAPAFSCSDLLNCALSLKGDLARDALPLQQYKLPKTYLAERNKLVVPAVEKYPSGVAFKDLSQAQLQHYMKESAQLLSEKIAFKTSDFSRGSPNAKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQVYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDSSLGLARTPAGEPGTEPPPPLPQQPPMTLPPLQPPLPTPGPLQPGLHQGHQ" } }, { "url": "https://www.uniprot.org/uniprot/A0PJY2#A0PJY2-3", "isoform_ac": "A0PJY2-3", "locus": {}, "sequence": { "header": "sp|A0PJY2-3|FEZF1_HUMAN Isoform 3 of Fez family zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FEZF1 PE=1 SV=1 CANONICAL=A0PJY2-1", "length": 471, "sequence": "MDSSCHNATTKMLATAPARGNMMSTSKPLAFSIERIMARTPEPKALPVPHFLQGALPKGEPKHSLHLNSSIPCMIPFVPVAYDTSPKAGVTGSEPRKASLEAPAAPAAVPSAPAFSCSDLLNCALSLKGDLARDALPLQQYKLVRPRVVNHSSFHAMGALCYLNRGDGPCHPAAGVNIHPVASYFLSSPLHPQPKTYLAERNKLVVPAVEKYPSGVAFKDLSQAQLQHYMKESAQLLSEKIAFKTSDFSRGSPNAKPKVFTCEVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQVYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDSSLGLARTPAGEPGTEPPPPLPQQPPMTLPPLQPPLPTPGPLQPGLHQGHQ" } }, { "url": "https://www.uniprot.org/uniprot/A0PJY2#C9J0C5-1", "isoform_ac": "C9J0C5-1", "locus": { "end_pos": 122304333, "strand": "+", "start_pos": 122304437, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000418046", "id": "ENST00000418046", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000406919", "id": "ENSP00000406919", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|C9J0C5-1|FEZF1_HUMAN Computationally mapped isoform of Fez family zinc finger protein 1 OS=Homo sapiens OX=9606 GN=FEZF1 PE=1 SV=1 CANONICAL=A0PJY2-1", "length": 35, "sequence": "MDSSCHNATTKMLATAPARGNMMSTSKPLAFSIER" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:389549", "resource": "KEGG Pathway", "id": "hsa:389549", "name": "" } ], "reaction_participants": [], "function": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "annotation": "Circulatinglong non-coding RNA FEZF1-AS1 and AFAP1-AS1 serve as potential diagnostic biomarkers for gastric cancer.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "annotation": "FEZF1-AS1 regulated activation of JAK-STAT3 signaling pathway by modulating STAT3 phosphorylation. Knockdown of FEZF1-AS1 significantly impaired the phosphorylation of STAT3. Study demonstrated that FEZF1-AS1 exerted an oncogenic role in ovarian cancer via modulating JAK-STAT3 pathway. Publication Status: Online-Only", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "annotation": "Fezf1 and Fezf2 accomplish both independent and redundant functions across diverse tissue and cell types. [Review] Review article", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "annotation": "Mechanism of lncRNA FEZF1-AS1 in promoting the occurrence and development of oral squamous cell carcinoma through targeting miR-196a.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "annotation": "Mutations in FEZF1 cause Kallmann syndrome.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "annotation": "Observational study of gene-disease association. (HuGE Navigator)", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "annotation": "Study is the first to report that ZNF312b, a novel transcription factor, was associated with tumorigenicity of gastric cancer. Erratum:[Cancer Res. 2009 May 1;69(9):4092]", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "annotation": "The aberrant expression of ZNF312b promotes gastric tumorigenesis through epigenetic modification of its promoter region and provides a molecular mechanism for ZNF312b expression to contribute to the progression of gastric cancer.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019784.2", "id": "NP_001019784.2", "database": "RefSeq" } ] }, { "url": "https://www.uniprot.org/uniprot/A0PJY2#function", "annotation": "Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors (By similarity).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0PJY2#function", "id": "A0PJY2", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZPD6-1", "protein_name": "Similar to zinc finger protein 312 (Predicted)", "sequence": { "length": 475, "sequence": "MDSSCLNATTKMLATAPARGNVMSTSKPLAFSIERIMARTPEPKALPVPHFLQGAVPKGDPKHSLHLNSSIPCMIPFVPVAYDTNSKAGVNGSEPRKASLEVPAPPAVAPSAPAFSCSDLLNCALSLKGDLARDALPLQQYKLVRPRVVNHSSFHAMGALCYLNRGDGPCHPAAGVNIHPVASYFLSSPLHPQPKTYLAERNKLVVPAVEKLPSGVAFKDLSQAQLHNYMKESAQLLSEKIAFKTSDFSRGSPNAKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQVYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDSSLGLTRTPTGEPGSDPPPQLQQPPPAPLPPLQPTLPPPGPLQSGLHQGHQ" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/19252", "id": "19252", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A0PJY2/", "id": "A0PJY2", "database": "OMA" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "gene_name": "Fezf1", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q0VDQ9-1", "protein_name": "Fez family zinc finger protein 1", "sequence": { "length": 475, "sequence": "MDSSCLNATTKMLATAPARGNVMSTSKPLAFSIERIMARTPEPKALPVPHFLQGAVPKGDPKHSLHLNSSIPCMIPFVPVAYDTNSKAGVNGSEPRKASLEVPAPPAVAPSAPAFSCSDLLNCALSLKGDLARDALPLQQYKLVRPRVVNHSSFHAMGALCYLNRGDGPCHPAASVNIHPVASYFLSSPLHPQPKTYLAERNKLVVPAVEKLPSGVAFKDLSQAQLQHYMKESAQLLSEKIAFKTSDFSRGSPNAKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQVYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDSSLGLTRTPTGEPSSDPPPQLQQPPPAPLPPLQPTLPPPGPLPSGLHQGHQ" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/19252", "id": "19252", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A0PJY2/", "id": "A0PJY2", "database": "OMA" } ], "common_name": "Mouse", "organism": "Mus musculus", "gene_name": "Fezf1", "tax_id": 10090 } ], "interactions": [], "synthesized_glycans": [], "snv": [ { "comment": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.1%). 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"https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000992", "uberon": "0000992", "name": "Ovary" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000996", "uberon": "0000996", "name": "Vagina" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001043", "uberon": "0001043", "name": "Esophagus" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001150", "uberon": "0001150", "name": "Body of pancreas" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001155", "uberon": "0001155", "name": "Colon" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001160", "uberon": "0001160", "name": "Fundus of stomach" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001161", "uberon": "0001161", "name": "Body of stomach" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001255", "uberon": "0001255", "name": "Urinary bladder" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001987", "uberon": "0001987", "name": "Placenta" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002046", "uberon": "0002046", "name": "Thyroid gland" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002048", "uberon": "0002048", "name": "Lung" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002107", "uberon": "0002107", "name": "Liver" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002367", "uberon": "0002367", "name": "Prostate gland" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002367", "uberon": "0002367", "name": "Prostate gland" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002369", "uberon": "0002369", "name": "Adrenal gland" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0009853", "uberon": "0009853", "name": "Body of uterus" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0009853", "uberon": "0009853", "name": "Body of uterus" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000128610", "id": "ENSG00000128610", "database": "Bgee" } ] } ], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0PJY2", "name": "FEZF1", "locus": { "end_pos": 122301394, "strand": "-", "start_pos": 122310691, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENSG00000128610", "id": "ENSG00000128610", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A0PJY2#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "Fez family zinc finger protein 1" }, { "url": "https://www.uniprot.org/uniprot/A0PJY2#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "Zinc finger protein 312B" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0PJY2", "type": "synonym", "resource": "RefSeq", "name": "fez family zinc finger protein 1 isoform 1" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0PJY2", "type": "synonym", "resource": "RefSeq", "name": "zinc finger protein 312B; fez family zinc finger protein 1" } ] }