{
    "uniprot_canonical_ac": "A0A0G2JZP7-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A0A0G2JZP7-1|A0A0G2JZP7_RAT Isoform 1 of SPG11 vesicle-trafficking-associated, spatacsin  OS=Rattus norvegicus OX=10116 GN=Spg11 PE=4 SV=1 CANONICAL=A0A0G2JZP7-1", 
        "length": 2465, 
        "sequence": "MTGAGPLSVHVRVTRSKTPRRSVTHSGASTGRNVRAKMAAKPGPGSAASPGCAGAMERVLPMLLVRIPAEETAQLGPRAQLHRELEALGSLTAAGSLQVLSLAPGSRGGSSCRLQGPFRQFLWEESQNSTSADKPRVLVAREDCGLLIYEFDLRDGRCDAALLHSCCGRTLQKLTEDQGVSISFKSLRILSFDNSTSLLLINECLVVRVVFPGRESGIGVLGCLSLPLPAQAVDTIIDVQLCKRFLFLLSTLGWIHIFDTVKGMHVARVDLALPREDSEQQEPASISSFMSLKVSRDLDVLLLVSSSSTAVALNLHLYFRLHPGHLLCEGTLQDLPIEGPTGIDEDDLVNSAHNMKLTKVSFQVDRSWRAQLASLNESVRSSEPELSCYPPWFQGALCLESLESGNHSPIVPNHVFIPGDVPSGQYAFPQKEHSKTSEPRPWRTMHLSEQEQPTELTCLSVTGFTALFIQAVGTTSCTVVLWDLETQSMQCFSLSQKCTPVDISGDQQLCLALTENGLSLILFGLTQEEFLNRLMIHGSASTVDSLCHLNGWGRCSIPIHALEAGIENRQLDTVDFFLKSKENLLTPSSKSPAPDQQQHFSSQLYLRQVEEMTPALDLLCSAIRESDSETQSKHFAEQLLHLTLSFLNKQMRELFDHTEELDEHLQKGAAILTSYINELRTFMIKFPWKPGDAIDESDENEEVLTVKEGQVWEELRSEEVIADAILNNRIPEAQTFFRITGHSAQRLEELVRIGLDLAFDSLKKNSVEEASRLLRNMGFSVEDELLKISFYTTDKNIRDFLVEILKEKECFSEKERRTVDFVHQAERLYSGHFQENAPMQAFPRYWIKEQDCFKHKSVLDTFLKCDTKDEFTKQDHRIALNWAHWWDRQTQECILLPRISSEEYKAHSPEALWRHLTARHDWSSISLWMEEFQAQETVSPQQSKWPPLSAAVIEQNTCCSRHMRNAILDQLARCGIFLASELEDFELLLLRLSRIGGVMQDALPVQSYRSSAGCNFDSQVILYCLEHGLQHLLYVYLDYYKLSPGNCPFLEKKELHEAHPWLEFLVQCRQVSSNLTDPKLIFQASLANAQISIPTNQASVSSMLLEGHTLLALATTMYAPGGVSQVIQHEDSENCLKKVDPQLLKMALTPYPKLKAALFPQCTAPSILPSDITLYHLIQSLPPFDPSRLFGWQSANTLAIGDAAGQLPHFSSPDLVSKYAVVEQLSYTYYLHHGRPSFAFGTFLVQELIKSKTPKQLIQQVGKEAYTLGLSSFHNPSVGAACVCFLELLGLSSLKLRVDLKMANVVLGSRRRNEDAHPSFIRESLAEKLSKLADGDRATTEELLVLLEEGVWDSIEQQGFNRLSSESSSQWSLVLQFCMLHDMKLSVSYLRECAKANDWLQFLVHSQLHNYHPEEVETLLQYFSPVLQSHLKLASEKLSSGSISKDDSCLQELQKNKETSDFFEILHRCSDESASWCWLLAEAVRHRVPILSVLASCIQGASAVPCLCVWIVTSVEDKVAAEAIEHIQISVEDHHWSLEDLSIIWRTVLTRRKIHTLIRGFRLFIKDSPLLLIMEMYELCVFFKNYGKAKVKLVEFQKSLEMLDTVATRVLPVIPATWMREQVCFLLKLMPQQCETQYELQKVLQLFVGMEQLFSDGPDVQKLYRLSQVLKDTPITISPAVISSYSTESLQRECRSILEKLKADGQFAVARRVAELASLPVDGLVIEQLTQEMQMLTHTQQWSLKQARLDFWRKCHENFKKNSVSNRAASSFFSSQAPEASEHPAEQGSLEERHLLLTLAGHWLAQEEPVPVEELEELEKQIWLCRIAQHTCGGAEEETKPSLSQHKLAPAELSSDSSASEFSFSKLAALNTSKYLDLNGLPSKEMCENTLEHREQESLNTLIGQLLDGGCVHEASRVCRYFRVYSQDLVLLLHCRALASAEASMEDLHSEIRALLSNATLPEDLESPGVPLRKVHSTSSLDSLSFAMVPPTDEVARSLQTLISRCLHGKDYCRQVLCLYELAKELGCSYGDVATRDSEAMLRAILASQRPDRCRQAQVFINTQGLEPDTVAELVAEEVTRELLTPSEGAGEKQPFNLAEESQTFLQLTALCQDRTLVGMKLLDKIPSVPHGELSCTTELLILAHHCFTCACYMEGIIRVLQAARMLTDNHLAPNEEYGLVVRLLTGIGRYNEMTYIFDLLHQKHYFEVLMRKKLDPTGTLKTALLDYIKRCHPGDSEKHNMIALCFSMCREIGENHEAAACIQLKLIESQPWEESLKDGAQLKQLLLKALTLMLDAAESYAKDSCVRQALHCNRLTKLITLQIHFLNSGQNTMLINLGHQKLMDCIMTLPRFYQASIVAEAYDFVPDWAEVLYQQVILKGDFSYLEEFKQQKLLKPNIFEDISKKYKQHQPTDRVTENLKKLLSYCEDIYLYYKLAYEHKFFEIVNMLLKDPQTGCCLKDMLAG"
    }, 
    "uniprot_id": "A0A0G2JZP7_RAT", 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                    "id": "A0A0G2JZP7", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "reaction_enzymes": [], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/17322883", 
                    "type": "PubMed", 
                    "id": "17322883"
                }
            ], 
            "title": "Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum.", 
            "journal": "Nature genetics", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178500.1", 
                    "id": "NP_001178500.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Stevanin G, Santorelli FM, Azzedine H, Coutinho P, Chomilier J, Denora PS, Martin E, Ouvrard-Hernandez AM, Tessa A, Bouslam N, Lossos A, Charles P, Loureiro JL, Elleuch N, Confavreux C, Cruz VT, Ruberg M, Leguern E, Grid D, Tazir M, Fontaine B, Filla A, Bertini E, Durr A, Brice A", 
            "date": "2007"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/17897319", 
                    "type": "PubMed", 
                    "id": "17897319"
                }
            ], 
            "title": "Integral and associated lysosomal membrane proteins.", 
            "journal": "Traffic (Copenhagen, Denmark)", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178500.1", 
                    "id": "NP_001178500.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Schroder B, Wrocklage C, Pan C, Jager R, Kosters B, Schafer H, Elsasser HP, Mann M, Hasilik A", 
            "date": "2007"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/24794856", 
                    "type": "PubMed", 
                    "id": "24794856"
                }
            ], 
            "title": "Dysfunction of spatacsin leads to axonal pathology in SPG11-linked hereditary spastic paraplegia.", 
            "journal": "Human molecular genetics", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178500.1", 
                    "id": "NP_001178500.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Perez-Branguli F, Mishra HK, Prots I, Havlicek S, Kohl Z, Saul D, Rummel C, Dorca-Arevalo J, Regensburger M, Graef D, Sock E, Blasi J, Groemer TW, Schlotzer-Schrehardt U, Winkler J, Winner B", 
            "date": "2014"
        }
    ], 
    "uniprot_ac": "A0A0G2JZP7", 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A0G2JZP7", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "RGD1562529"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A0G2JZP7", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Spg11"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Spg11"
        }
    ], 
    "reactions": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7#A0A0G2JZP7-1", 
            "isoform_ac": "A0A0G2JZP7-1", 
            "locus": {
                "end_pos": 113999803, 
                "strand": "+", 
                "start_pos": 114064500, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000080253", 
                        "id": "ENSRNOT00000080253", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000071131", 
                        "id": "ENSRNOP00000071131", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2JZP7-1|A0A0G2JZP7_RAT Isoform 1 of SPG11 vesicle-trafficking-associated, spatacsin  OS=Rattus norvegicus OX=10116 GN=Spg11 PE=4 SV=1 CANONICAL=A0A0G2JZP7-1", 
                "length": 2465, 
                "sequence": "MTGAGPLSVHVRVTRSKTPRRSVTHSGASTGRNVRAKMAAKPGPGSAASPGCAGAMERVLPMLLVRIPAEETAQLGPRAQLHRELEALGSLTAAGSLQVLSLAPGSRGGSSCRLQGPFRQFLWEESQNSTSADKPRVLVAREDCGLLIYEFDLRDGRCDAALLHSCCGRTLQKLTEDQGVSISFKSLRILSFDNSTSLLLINECLVVRVVFPGRESGIGVLGCLSLPLPAQAVDTIIDVQLCKRFLFLLSTLGWIHIFDTVKGMHVARVDLALPREDSEQQEPASISSFMSLKVSRDLDVLLLVSSSSTAVALNLHLYFRLHPGHLLCEGTLQDLPIEGPTGIDEDDLVNSAHNMKLTKVSFQVDRSWRAQLASLNESVRSSEPELSCYPPWFQGALCLESLESGNHSPIVPNHVFIPGDVPSGQYAFPQKEHSKTSEPRPWRTMHLSEQEQPTELTCLSVTGFTALFIQAVGTTSCTVVLWDLETQSMQCFSLSQKCTPVDISGDQQLCLALTENGLSLILFGLTQEEFLNRLMIHGSASTVDSLCHLNGWGRCSIPIHALEAGIENRQLDTVDFFLKSKENLLTPSSKSPAPDQQQHFSSQLYLRQVEEMTPALDLLCSAIRESDSETQSKHFAEQLLHLTLSFLNKQMRELFDHTEELDEHLQKGAAILTSYINELRTFMIKFPWKPGDAIDESDENEEVLTVKEGQVWEELRSEEVIADAILNNRIPEAQTFFRITGHSAQRLEELVRIGLDLAFDSLKKNSVEEASRLLRNMGFSVEDELLKISFYTTDKNIRDFLVEILKEKECFSEKERRTVDFVHQAERLYSGHFQENAPMQAFPRYWIKEQDCFKHKSVLDTFLKCDTKDEFTKQDHRIALNWAHWWDRQTQECILLPRISSEEYKAHSPEALWRHLTARHDWSSISLWMEEFQAQETVSPQQSKWPPLSAAVIEQNTCCSRHMRNAILDQLARCGIFLASELEDFELLLLRLSRIGGVMQDALPVQSYRSSAGCNFDSQVILYCLEHGLQHLLYVYLDYYKLSPGNCPFLEKKELHEAHPWLEFLVQCRQVSSNLTDPKLIFQASLANAQISIPTNQASVSSMLLEGHTLLALATTMYAPGGVSQVIQHEDSENCLKKVDPQLLKMALTPYPKLKAALFPQCTAPSILPSDITLYHLIQSLPPFDPSRLFGWQSANTLAIGDAAGQLPHFSSPDLVSKYAVVEQLSYTYYLHHGRPSFAFGTFLVQELIKSKTPKQLIQQVGKEAYTLGLSSFHNPSVGAACVCFLELLGLSSLKLRVDLKMANVVLGSRRRNEDAHPSFIRESLAEKLSKLADGDRATTEELLVLLEEGVWDSIEQQGFNRLSSESSSQWSLVLQFCMLHDMKLSVSYLRECAKANDWLQFLVHSQLHNYHPEEVETLLQYFSPVLQSHLKLASEKLSSGSISKDDSCLQELQKNKETSDFFEILHRCSDESASWCWLLAEAVRHRVPILSVLASCIQGASAVPCLCVWIVTSVEDKVAAEAIEHIQISVEDHHWSLEDLSIIWRTVLTRRKIHTLIRGFRLFIKDSPLLLIMEMYELCVFFKNYGKAKVKLVEFQKSLEMLDTVATRVLPVIPATWMREQVCFLLKLMPQQCETQYELQKVLQLFVGMEQLFSDGPDVQKLYRLSQVLKDTPITISPAVISSYSTESLQRECRSILEKLKADGQFAVARRVAELASLPVDGLVIEQLTQEMQMLTHTQQWSLKQARLDFWRKCHENFKKNSVSNRAASSFFSSQAPEASEHPAEQGSLEERHLLLTLAGHWLAQEEPVPVEELEELEKQIWLCRIAQHTCGGAEEETKPSLSQHKLAPAELSSDSSASEFSFSKLAALNTSKYLDLNGLPSKEMCENTLEHREQESLNTLIGQLLDGGCVHEASRVCRYFRVYSQDLVLLLHCRALASAEASMEDLHSEIRALLSNATLPEDLESPGVPLRKVHSTSSLDSLSFAMVPPTDEVARSLQTLISRCLHGKDYCRQVLCLYELAKELGCSYGDVATRDSEAMLRAILASQRPDRCRQAQVFINTQGLEPDTVAELVAEEVTRELLTPSEGAGEKQPFNLAEESQTFLQLTALCQDRTLVGMKLLDKIPSVPHGELSCTTELLILAHHCFTCACYMEGIIRVLQAARMLTDNHLAPNEEYGLVVRLLTGIGRYNEMTYIFDLLHQKHYFEVLMRKKLDPTGTLKTALLDYIKRCHPGDSEKHNMIALCFSMCREIGENHEAAACIQLKLIESQPWEESLKDGAQLKQLLLKALTLMLDAAESYAKDSCVRQALHCNRLTKLITLQIHFLNSGQNTMLINLGHQKLMDCIMTLPRFYQASIVAEAYDFVPDWAEVLYQQVILKGDFSYLEEFKQQKLLKPNIFEDISKKYKQHQPTDRVTENLKKLLSYCEDIYLYYKLAYEHKFFEIVNMLLKDPQTGCCLKDMLAG"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7#D3Z9Z3-1", 
            "isoform_ac": "D3Z9Z3-1", 
            "locus": {
                "end_pos": 113999803, 
                "strand": "+", 
                "start_pos": 114064389, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000022875", 
                        "id": "ENSRNOT00000022875", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000022875", 
                        "id": "ENSRNOP00000022875", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|D3Z9Z3-1|A0A0G2JZP7_RAT Computationally mapped isoform of SPG11 vesicle-trafficking-associated, spatacsin  OS=Rattus norvegicus OX=10116 GN=Spg11 PE=4 SV=2 CANONICAL=A0A0G2JZP7-1", 
                "length": 2315, 
                "sequence": "MAAKPGPGSAASPGCAGAMERVLPMLLVRIPAEETAQLGPRAQLHRELEALGSLTAAGSLQVLSLAPGSRGGSSCRLQGPFRQFLWEESQNSTSADKPRVLVAREDCGLLIYEFDLRDGRCDAALLHSCCGRTLQKLTEDQGVSISFKSLRILSFDNSTSLLLINECLVVRVVFPGRESGIGVLGCLSLPLPAQAVDTIIDVQLCKRFLFLLSTLGWIHIFDTVKGMHVARVDLALPREDSEQQEPASISSFMSLKVSRDLDVLLLVSSSSTAVALNLHLYFRLHPGHLLCEGTLQDLPIEGPTGIDEDDLVNSAHNMKLTKVSFQVDRSWRAQLASLNESVRSSEPELSCYPPWFQGALCLESLESGNHSPIVPNHVFIPGDVPSGQYAFPQKEHSKTSEPRPWRTMHLSEQEQPTELTCLSVTGFTALFIQAVGTTSCTVVLWDLETQSMQCFSLSQKCTPVDISGDQQLCLALTENGLSLILFGLTQEEFLNRLMIHGSASTVDSLCHLNGWGRCSIPIHALEAGIENRQLDTVDFFLKSKENLLTPSSKSPAPDQQQHFSSQLYLRQVEEMTPALDLLCSAIRESDSETQSKHFAEQLLHLTLSFLNKQMRELFDHTEELDEHLQKGAAILTSYINELRTFMIKFPWKPGDAIDESDENEEVLTVKEGQVWEELRSEEVIADAILNNRIPEAQTFFRITGHSAQRLEELVRIGLDLAFDSLKKNSVEEASRLLRNMGFSVEDELLKISFYTTDKNIRDFLVEILKEKECFSEKERRTVDFVHQAERLYSGHFQENAPMQAFPRYWIKEQDCFKHKSVLDTFLKCDTKDEFTKQDHRIALNWAHWWDRQTQECILLPRISSEEYKAHSPEALWRHLTARHDWSSISLWMEEFQAQETVSPQQSKWPPLSAAVIEQNTCCSRHMRNAILDQLARCGIFLASELEDFELLLLRLSRIGGVMQDALPVQSYRSSAGCNFDSQVILYCLEHGLQHLLYVYLDYYKLSPGNCPFLEKKELHEAHPWLEFLVQCRQVSSNLTDPKLIFQASLANAQISIPTNQASVSSMLLEGHTLLALATTMYAPGGVSQVIQHEDSENCLKKVDPQLLKMALTPYPKLKAALFPQCTAPSILPSDITLYHLIQSLPPFDPSRLFGWQSANTLAIGDAAGQLPHFSSPDLVSKYAVVEQLSYTYYLHHGRPSFAFGTFLVQELIKSKTPKQLIQQVGKEAYTLGLSSFHNPSVGAACVCFLELLGLSSLKLRVDLKMANVVLGSRRRNEDAHPSFIRESLAEKLSKLADGDRATTEELLVLLEEGVWDSIEQQGFNRLSSESSSQWSLVLQFCMLHDMKLSVSYLRECAKANDWLQFLVHSQLHNYHPEEVETLLQYFSPVLQSHLKLASEKLSSGSISKDDSCLQELQKNKETSDFFEILHRCSDESASWCWLLAEAVRHRVPILSVLASCIQGASAVPCLCVWIVTSVEDKVAAEAIEHIQISVEDHHWSLEDLSIIWRTVLTRRKIHTLIRGFRLFIKDSPLLLIMEMYELCVFFKNYGKAKVKLVEFQKSLEMLDTVATRVLPVIPATWMREQVCFLLKLMPQQCETQYELQKVLQLFVGMEQLFSDGPDVQKLYRLSQVLKDTPITISPAVISSYSTESLQRECRSILEKLKADGQFAVARRVAELASLPVDGLVIEQLTQEMQMLTHTQQWSLKQARLDFWRKCHENFKKNSVSNRAASSFFSSQAPEASEHPAEQGSLEERHLLLTLAGHWLAQEEPVPVEELEELEKQIWLCRIAQHTCGGAEEETKPSLSQHKLAPAELSSDSSASEFSFSKLAALNTSKYLDLNGLPSKEMCENTLEHREQESLNTLIGQLLDGGCVHEASRVCRYFRVYSQDLVLLLHCRALASAEASMEDLHSEIRALLSNATLPEDLESPGVPLRKVHSREKQPFNLAEESQTFLQLTALCQDRTLVGMKLLDKIPSVPHGELSCTTELLILAHHCFTCACYMEGIIRVLQAARMLTDNHLAPNEEYGLVVRLLTGIGRYNEMTYIFDLLHQKHYFEVLMRKKLDPTGTLKTALLDYIKRCHPGDSEKHNMIALCFSMCREIGENHEAAACIQLKLIESQPWEESLKDGAQLKQLLLKALTLMLDAAESYAKDSCVRQALHCNRLTKLITLQIHFLNSGQNTMLINLGHQKLMDCIMTLPRFYQASIVAEAYDFVPDWAEVLYQQVILKGDFSYLEEFKQQKLLKPNIFEDISKKYKQHQPTDRVTENLKKLLSYCEDIYLYYKLAYEHKFFEIVNMLLKDPQTGCCLKDMLAG"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:311372", 
            "resource": "KEGG Pathway", 
            "id": "rno:311372", 
            "name": ""
        }
    ], 
    "reaction_participants": [], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q3UHA3-1", 
            "protein_name": "Spatacsin", 
            "sequence": {
                "length": 2430, 
                "sequence": "MAAQPGPGSAASPGCAGAMERVLPMLLVRIPAEETAQLGPRAQLHRELEALGSLTAAGSLQVLSLAPGSRGGSSCCLPGPFRQFLWEESQNSTSRDRPKLLVAREDYELLVYEFDLRDGRCDAALLHGCCGRTLQKLTEDQGVSISFKSLRILSFHNNTSLLLINRCLILRVVFPGKEPGVPVLDCLSLPLPAQAADMIIDAQLCERFLFVLSTVGLIYIFNTMDGTQVAQVDLALLREDSEQLEPASVSSFTSLRVSQDLDVLVLVSSASTAVALNLHLYFRQHPGHLLCEGTLEDLPIEGPPGIDEDDLVNSAHNMKLSKVSFQVDRSWRAQLLSLNESVRGSEPEVSCCAPWFQSALRLESLESADHTPTVPTHVFIPGDVPRGRCAFPQKEHVKSSDPGRPWKTMHLSEHEQPTELTCLSVTGFTALFTWAVGATSCTIGLWDLETQSMQCFSLSQKCTPVDIGGDQQLCLALTDDGLSLILFGLTQEEFLNRLMIHGSASTVDSLCHLNGWGRCSIPIHALEAGIENRQLDTVDFFLKSKENLLTPSSQSPAPDQQHPFSSHLYLRQVEEMSPALDLLCSAIRESDSETQSKHFAEQLLHLTLSFLNKQIRELCVHTEELDEHFQKGVAILTSYINELRTFMIKFPWKPGDAIDESDVNEGVVTVKEDRVWEELSFEEVIADAILNNRIPEAQTFFRISGHSAQRLEELVRIGLDLAFDSLKKNNVEEASRLLRNMGFSVEDELLKICFYTTDKNIRDFLVEILKEKECFSEKERRTVDFVHQLEALYSGHFQENAQTQAFPRYWIKEQDCFKHKSVLDTFLKYDKKDEFHKQDHRIALNWAHRWDLQTQECILLRRLSPEEYKARSPEALWRHLTARHDCSSISLWMEEFQTQETESPQQSKWPPLSADIIEQGTCCHSHMRNEILDKLARSGIFLASELEDFERLLLRLSRIGGVMQDSLPVQSYKSRAGCDFHSRFILYCLEHGLQHLLYTYLDYYKLSPGNCPFLEKKELHEAHPWLEFLVQCRQVSSNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYAPGGVSQVIQNEDSENCLKKVDPQLLKVALTPYPKLKAALFPQYTAPSILPSDITLYHLIQSLPPFDPSRLFVWQSANTLAIGDTGSQLPHFSSPDLVSKYAVLERLNYAYYLHHGRPSFAFGTFLVQELIKSKTPKQLIQQVGKEAYTLGLSSFTNPSVGAACVCFLELLGLSSLKLRVDLKMANVILGSKRRDEDARSSFIRESLAEKLSKLADGDRAATEELLVLLEEGVWDSIEQQGFSRLSSESSSQWALVLQFCMLHDRKLSVSYLRECAKANDWLQFLVHSQLHNYHPAEVESLLQYFSPVLQSHLKLASEKLSSGSISRDDSCLQELQKNKGETSNFFEILHRCSDESTSWSWLLAEAVRHRAPILSVLASCVQGASVVSCLCVWIVTSVEDKVAAEAMGHIQISVEDHHWSLKDLSIIWRTVLTRRKSHTLIRGFQLFIKDSPLLLIMEMYELCMFFKNYEKAKVKLLEFQKSLETLDTVAARVLPIIPASWMKDQVCFLLKLMPQQCETQYELGKLLQLFVGTEQLFSDGPDVQKLCLLSQVLKDTPIAISPAVISSYSTENFQRECRSILEKLKADGQFAVARRVAELAALPVDSLLIEQLTQEMQTLTHTPQWSLKQERLGFWKKCHEIFKKNSISKRAASSFFSSQAPEVSEHPAEQGSLEERHLLLTLAGHWLAQEEPVPVEELEGLEKQIWICRVAQHTCGGAEEEAKPSLSQHKLAAAELSFDSLASELSFSKLAALNTSKYLGLNDLPSKTTCENRLKHKEQESLNTLIGQLLDGGCVHEASRVCQYFRFYSQDLVLVLHCRALASAEATMEDLHSEIRALLSSAAQPEDLESPSVPLRKAHSSSSLDSQSFVMVPPTDEVAQNLHTLISKCLHGKNYCRQVLCLYELAKDLGCSYGDVAARDSEAMLRAILASQRPDRCRQAQVFINTQGLEADTVAELVAEEVTRELLTPSEGTGEKQPFNPAEESQTFLQLTALCQDRTLVGMKLLDKIPSVPHGELSCTTELLILAHHCFTFTCHMEGITRVLQAARMLTDNHLAPNEEYGLVVRLLTGIGRYNEMTYIFDLLHQKHYFEVLMRKKLDPTGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAACIQLKLIESQPWEESLKDGAQLKQLLLKALTLMLDAAESYAKDSCVRQALHCNRLTKLITLQIHFLNSGQNTMLINLGHQKLMDCIMTLPRFYQASIVAEAYDFVPDWAEVLYQQVILKGDFSYLEEFKQQKLLRPNIFEDISKKYKQHQPTDRVTENLKKLLSYCEDIYLYYKLAYEHKFFEIVNMLLKDPQTGCCLKDMLAG"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2JZP7/", 
                    "id": "A0A0G2JZP7", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/41614", 
                    "id": "41614", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Spg11", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q96JI7-1", 
            "protein_name": "Spatacsin", 
            "sequence": {
                "length": 2443, 
                "sequence": "MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNNQIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTDAIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRIDSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVKGQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLYLGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFNKQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNNYMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNYKTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLEKKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDPQLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSRLFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYLHNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSIGAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFIRESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESSSQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNYHPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQELQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVLASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDLSVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFRNYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLMLQQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTSIAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPVDNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSISSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVPLDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELSFDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNFLIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEASMEDLHPEIHALLQSAELLEEEAPDIPLRRVHSTSSLDSQKFVTVPSSNEVVTNLEVLTSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAAQDGEAMLRKILASQQPDRCKRAQAFISTQGLKPDTVAELVAEEVTRELLTSSQGTGHKQMFNPTEESQTFLQLTTLCQDRTLVGMKLLDKISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLQAAHMLTDNHLAPSEEYGLVVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAARIQLKLIESQPWEDSLKDGHQLKQLLLKALTLMLDAAESYAKDSCVRQAQHCQRLTKLITLQIHFLNTGQNTMLINLGRHKLMDCILALPRFYQASIVAEAYDFVPDWAEILYQQVILKGDFNYLEEFKQQRLLKSSIFEEISKKYKQHQPTDMVMENLKKLLTYCEDVYLYYKLAYEHKFYEIVNVLLKDPQTGCCLKDMLAG"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2JZP7/", 
                    "id": "A0A0G2JZP7", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/41614", 
                    "id": "41614", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "SPG11", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178500.1", 
        "ac": "NP_001178500.1", 
        "name": "spatacsin", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleolus", 
                        "id": "GO:0005730"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytosol", 
                        "id": "GO:0005829"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "plasma membrane", 
                        "id": "GO:0005886"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "axon", 
                        "id": "GO:0030424"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "dendrite", 
                        "id": "GO:0030425"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "synapse", 
                        "id": "GO:0045202"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasmic vesicle", 
                        "id": "GO:0031410"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "21545838", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 9, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008088", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "axo-dendritic transport", 
                        "id": "GO:0008088"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "chemical synaptic transmission", 
                        "id": "GO:0007268"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "lysosome organization", 
                        "id": "GO:0007040"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048675", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "axon extension", 
                        "id": "GO:0048675"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090389", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "phagosome-lysosome fusion involved in apoptotic cell clearance", 
                        "id": "GO:0090389"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090659", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "walking behavior", 
                        "id": "GO:0090659"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048489", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
                                "id": "A0A0G2JZP7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "synaptic vesicle transport", 
                        "id": "GO:0048489"
                    }
                ], 
                "total": 7, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 1076, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1074
        }, 
        {
            "end_pos": 130, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 128
        }, 
        {
            "end_pos": 1873, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1871
        }, 
        {
            "end_pos": 196, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 194
        }, 
        {
            "end_pos": 1960, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1958
        }, 
        {
            "end_pos": 378, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 376
        }, 
        {
            "end_pos": 408, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 406
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000021954", 
            "id": "ENSRNOG00000021954", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/311372", 
            "id": "311372", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028103", 
            "id": "IPR028103", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028107", 
            "id": "IPR028107", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:311372", 
            "id": "rno:311372", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/SYCEDIY/", 
            "id": "SYCEDIY", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=6211at2759", 
            "id": "6211at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13650", 
            "id": "PTHR13650", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF14649", 
            "id": "PF14649", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178500", 
            "id": "NP_001178500", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178500.1", 
            "id": "NP_001178500.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1562529", 
            "id": "1562529", 
            "database": "RGD"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
            "id": "A0A0G2JZP7", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7-1", 
            "id": "A0A0G2JZP7-1", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/D3Z9Z3", 
            "id": "D3Z9Z3", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/D3Z9Z3-1", 
            "id": "D3Z9Z3-1", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [
        {
            "disease_id": "DOID:0060197", 
            "synonyms": [
                {
                    "url": "http://disease-ontology.org/term/DOID:0060197", 
                    "resource": "Disease Ontology", 
                    "description": "", 
                    "name": "ALS5", 
                    "id": "DOID:0060197"
                }, 
                {
                    "url": "http://disease-ontology.org/term/DOID:0060197", 
                    "resource": "Disease Ontology", 
                    "description": "", 
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                    "description": "Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the SPG11 gene.", 
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                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0011196", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "SPG11 amyotrophic lateral sclerosis", 
                    "id": "MONDO:0011196"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0011196", 
                    "resource": "MONDO", 
                    "description": "", 
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                    "id": "MONDO:0011196"
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                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0011196", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "amyotrophic lateral sclerosis caused by mutation in SPG11", 
                    "id": "MONDO:0011196"
                }, 
                {
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                    "description": "", 
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                    "id": "MONDO:0011196"
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                    "resource": "MONDO", 
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                    "name": "ALS5", 
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                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0011196", 
                    "resource": "MONDO", 
                    "description": "", 
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                    "id": "MONDO:0011196"
                }, 
                {
                    "url": "https://www.omim.org/entry/602099", 
                    "resource": "MIM", 
                    "description": "Amyotrophic lateral sclerosis 5, juvenile", 
                    "name": "Amyotrophic lateral sclerosis 5, juvenile", 
                    "id": "MIM:602099"
                }
            ], 
            "recommended_name": {
                "url": "http://disease-ontology.org/term/DOID:0060197", 
                "resource": "Disease Ontology", 
                "description": "An amyotrophic lateral sclerosis that has_material_basis_in mutation in the SPG11 gene on chromosome 15q21.", 
                "name": "amyotrophic lateral sclerosis type 5", 
                "id": "DOID:0060197"
            }, 
            "evidence": [
                {
                    "url": "https://www.alliancegenome.org/gene/0060197#disease-associations", 
                    "id": "0060197", 
                    "database": "Alliance of Genome Resources"
                }
            ]
        }, 
        {
            "disease_id": "DOID:0110176", 
            "synonyms": [
                {
                    "url": "http://disease-ontology.org/term/DOID:0110176", 
                    "resource": "Disease Ontology", 
                    "description": "", 
                    "name": "Charcot-Marie-Tooth neuropathy type 2X", 
                    "id": "DOID:0110176"
                }, 
                {
                    "url": "http://disease-ontology.org/term/DOID:0110176", 
                    "resource": "Disease Ontology", 
                    "description": "", 
                    "name": "autosomal recessive axonal Charcot-Marie-Tooth disease type 2X", 
                    "id": "DOID:0110176"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "Any Charcot-Marie-Tooth disease in which the cause of the disease is a mutation in the SPG11 gene.", 
                    "name": "Charcot-Marie-Tooth disease axonal type 2X", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Charcot-Marie-Tooth disease, axonal, type 2x", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Charcot-Marie-Tooth disease, axonal, type 2X; CMT2X", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "autosomal recessive Charcot-Marie-Tooth disease type 2 due to SPG11 mutation", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "autosomal recessive Charcot Marie Tooth disease type 2X", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Charcot-Marie-Tooth neuropathy, type 2X", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "autosomal recessive axonal Charcot-Marie-Tooth disease type 2X", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "ARCMT2X", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Charcot-Marie-Tooth neuropathy type 2X", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Charcot-Marie-Tooth disease caused by mutation in SPG11", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "CMT2X", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "Charcot-Marie-Tooth disease, axonal, autosomal recessive, type 2X", 
                    "id": "MONDO:0014726"
                }, 
                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0014726", 
                    "resource": "MONDO", 
                    "description": "", 
                    "name": "autosomal recessive Charcot-Marie-Tooth disease type 2X", 
                    "id": "MONDO:0014726"
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                {
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                    "resource": "MIM", 
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                    "name": "Charcot-Marie-Tooth disease 2X", 
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                    "description": "", 
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                {
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                    "resource": "Disease Ontology", 
                    "description": "", 
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                {
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                    "description": "", 
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                    "resource": "MONDO", 
                    "description": "", 
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                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0011445", 
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                {
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                    "resource": "MONDO", 
                    "description": "", 
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                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0011445", 
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                    "description": "", 
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                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0011445", 
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                    "name": "Nakamura Osame syndrome", 
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                    "description": "", 
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                {
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                {
                    "url": "https://monarchinitiative.org/disease/MONDO:0011445", 
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                {
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    ], 
    "phosphorylation": [], 
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        "chemical_mass": 277837.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZP7", 
            "name": "Spg11", 
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    ]
}