{
    "uniprot_canonical_ac": "A0A0G2JFS9-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A0A0G2JFS9-1|A0A0G2JFS9_MOUSE Isoform 1 of Cysteine protease  OS=Mus musculus OX=10090 GN=Atg4a-ps PE=3 SV=1 CANONICAL=A0A0G2JFS9-1", 
        "length": 396, 
        "sequence": "MESVMSKYENQILIFPDYLEEFPDTDELVWILGKQHPFKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWNWERQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVIKKLTLFDEWNSLAVYVSMDNTVVIEDIKKMCCVLPVGAADPAGDFLTVSNQSRDTSVPCSAWKPLLLIVPLRLGINQINPVYVEAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDIEESGLVDDQTFHCLQSPQRMSILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIESTEQLEDFELEEDFEILSVG"
    }, 
    "uniprot_id": "A0A0G2JFS9_MOUSE", 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9", 
                    "id": "A0A0G2JFS9", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "reaction_enzymes": [], 
    "publication": [], 
    "uniprot_ac": "A0A0G2JFS9", 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Atg4a-ps"
        }
    ], 
    "reactions": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9#A0A0G2JFS9-1", 
            "isoform_ac": "A0A0G2JFS9-1", 
            "locus": {
                "end_pos": 103644836, 
                "strand": "+", 
                "start_pos": 103646023, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000117271", 
                        "id": "ENSMUST00000117271", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000143291", 
                        "id": "ENSMUSP00000143291", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2JFS9-1|A0A0G2JFS9_MOUSE Isoform 1 of Cysteine protease  OS=Mus musculus OX=10090 GN=Atg4a-ps PE=3 SV=1 CANONICAL=A0A0G2JFS9-1", 
                "length": 396, 
                "sequence": "MESVMSKYENQILIFPDYLEEFPDTDELVWILGKQHPFKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWNWERQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVIKKLTLFDEWNSLAVYVSMDNTVVIEDIKKMCCVLPVGAADPAGDFLTVSNQSRDTSVPCSAWKPLLLIVPLRLGINQINPVYVEAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDIEESGLVDDQTFHCLQSPQRMSILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIESTEQLEDFELEEDFEILSVG"
            }
        }
    ], 
    "pathway": [], 
    "reaction_participants": [], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9#function", 
            "annotation": "Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9#function", 
                    "id": "A0A0G2JFS9", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q8WYN0-1", 
            "protein_name": "Cysteine protease ATG4A", 
            "sequence": {
                "length": 398, 
                "sequence": "MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLSADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSV"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2JFS9/", 
                    "id": "A0A0G2JFS9", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "ATG4A", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {}, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9", 
                                "id": "A0A0G2JFS9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cysteine-type endopeptidase activity", 
                        "id": "GO:0004197"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9", 
                                "id": "A0A0G2JFS9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9", 
                                "id": "A0A0G2JFS9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "protein transport", 
                        "id": "GO:0015031"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9", 
                                "id": "A0A0G2JFS9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "autophagy", 
                        "id": "GO:0006914"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 207, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 205
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000087119", 
            "id": "ENSMUSG00000087119", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005078", 
            "id": "IPR005078", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033474", 
            "id": "IPR033474", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", 
            "id": "IPR038765", 
            "database": "InterPro"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:3615624", 
            "id": "3615624", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/WSNIAVH/", 
            "id": "WSNIAVH", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22624", 
            "id": "PTHR22624", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22624:SF35", 
            "id": "PTHR22624:SF35", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF03416", 
            "id": "PF03416", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9", 
            "id": "A0A0G2JFS9", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9-1", 
            "id": "A0A0G2JFS9-1", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 45187.0, 
        "chemical_mass": 45187.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9", 
            "name": "Atg4a-ps", 
            "locus": {
                "end_pos": 103643954, 
                "strand": "-", 
                "start_pos": 103646068, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000087119", 
                        "id": "ENSMUSG00000087119", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "3.4.22.-"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JFS9#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Cysteine protease"
        }
    ]
}