{ "uniprot_canonical_ac": "A2RSQ0-1", "ptm_annotation": [], "sequence": { "header": "sp|A2RSQ0-1|DEN5B_MOUSE Isoform 1 of DENN domain-containing protein 5B OS=Mus musculus OX=10090 GN=Dennd5b PE=1 SV=2 CANONICAL=A2RSQ0-1", "length": 1274, "sequence": "MSGSSAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKEPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVYASSSCSMDSLASSIDEGDATSLLKLQRYNSYDINRDTLYVSKSICLITPLPFMQACKKFLFQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPNELPLSDYPLREACELLGLENLVQVFTCVLLEMQTLLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEGSLHSSESATKLKNMVLKDLANDKKNGNVPNNSVSVYELLKGSETIARLQALAKRTGVTMEKIDLPASLSEKEKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDSRIEKIRLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSATAQRRKERLRQSSEHIGLDSDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLLQFQDREEKQEHLTDSPVALGPERRKSDSGVMLPTLRVSLIQDMRHIQNMTEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTSASDEDLGKQCRTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFETTDQILDNEGDVLIQKPSSKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPAITRMYEENALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV" }, "uniprot_id": "", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017112", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "name": "Rab guanyl-nucleotide exchange factor activity", "id": "GO:0017112" } ], "total": 1, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "name": "integral component of membrane", "id": "GO:0016021" } ], "total": 1, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905885", "pmid": "30837651", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "name": "positive regulation of triglyceride transport", "id": "GO:1905885" } ], "total": 1, "name": "Biological Process" } ] }, "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/17242355", "type": "PubMed", "id": "17242355" } ], "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "authors": "Beausoleil S.A., Gerber S.A., Gygi S.P., Villen J.", "date": "2007" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/30837651", "type": "PubMed", "id": "30837651" } ], "title": "DENND5B Regulates Intestinal Triglyceride Absorption and Body Mass.", "journal": "Scientific reports", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_796166.2", "id": "NP_796166.2", "database": "RefSeq" } ], "authors": "Gordon SM, Neufeld EB, Yang Z, Pryor M, Freeman LA, Fan X, Kullo IJ, Biesecker LG, Remaley AT", "date": "2019" } ], "uniprot_ac": "A2RSQ0", "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2RSQ0", "type": "synonym", "resource": "RefSeq", "name": "9330160C06Rik; AI852444; D030011O10Rik; Gm17524" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2RSQ0", "type": "synonym", "resource": "RefSeq", "name": "Dennd5b" }, { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "type": "recommended", "resource": "UniProtKB", "name": "Dennd5b" } ], "reactions": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0#A2RSQ0-1", "isoform_ac": "A2RSQ0-1", "locus": { "end_pos": 148993709, "strand": "+", "start_pos": 149101309, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000111557", "id": "ENSMUST00000111557", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000107182", "id": "ENSMUSP00000107182", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2RSQ0-1|DEN5B_MOUSE Isoform 1 of DENN domain-containing protein 5B OS=Mus musculus OX=10090 GN=Dennd5b PE=1 SV=2 CANONICAL=A2RSQ0-1", "length": 1274, "sequence": "MSGSSAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKEPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVYASSSCSMDSLASSIDEGDATSLLKLQRYNSYDINRDTLYVSKSICLITPLPFMQACKKFLFQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPNELPLSDYPLREACELLGLENLVQVFTCVLLEMQTLLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEGSLHSSESATKLKNMVLKDLANDKKNGNVPNNSVSVYELLKGSETIARLQALAKRTGVTMEKIDLPASLSEKEKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDSRIEKIRLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSATAQRRKERLRQSSEHIGLDSDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLLQFQDREEKQEHLTDSPVALGPERRKSDSGVMLPTLRVSLIQDMRHIQNMTEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTSASDEDLGKQCRTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFETTDQILDNEGDVLIQKPSSKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPAITRMYEENALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV" } }, { "url": "https://www.uniprot.org/uniprot/A2RSQ0#B8JKU3-1", "isoform_ac": "B8JKU3-1", "locus": { "end_pos": 149068582, "strand": "+", "start_pos": 149101309, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000127727", "id": "ENSMUST00000127727", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000123568", "id": "ENSMUSP00000123568", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|B8JKU3-1|DEN5B_MOUSE Computationally mapped isoform of DENN domain-containing protein 5B OS=Mus musculus OX=10090 GN=Dennd5b PE=1 SV=1 CANONICAL=A2RSQ0-1", "length": 146, "sequence": "MSGSSAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAVLYQWLEADRHGKSQDTANTTSGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKEPQFHSFIITREDGSRTYGFVLTFYEEVT" } }, { "url": "https://www.uniprot.org/uniprot/A2RSQ0#E9Q0R9-1", "isoform_ac": "E9Q0R9-1", "locus": { "end_pos": 149068558, "strand": "+", "start_pos": 149080808, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000145555", "id": "ENSMUST00000145555", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000127731", "id": "ENSMUSP00000127731", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E9Q0R9-1|E9Q0R9_MOUSE Computationally mapped isoform of DENN domain-containing protein 5B OS=Mus musculus OX=10090 GN=Dennd5b PE=4 SV=1 CANONICAL=A2RSQ0-1", "length": 54, "sequence": "MLCMPKGLSFRTQADNKEPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAM" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:320560", "resource": "KEGG Pathway", "id": "mmu:320560", "name": "" }, { "reaction_list": [ "R-MMU-8875318", "R-MMU-8875320", "R-MMU-8876188", "R-MMU-8876190", "R-MMU-8876191", "R-MMU-8876193", "R-MMU-8876446", "R-MMU-8876454", "R-MMU-8876615", "R-MMU-8876616", "R-MMU-8876837", "R-MMU-8877308", "R-MMU-8877311", "R-MMU-8877451", "R-MMU-8877475", "R-MMU-8877612", "R-MMU-8877760", "R-MMU-8877813", "R-MMU-8877998", "R-MMU-8933446", "R-MMU-8933452" ], "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8876198", "id": "R-MMU-8876198", "name": "RAB GEFs exchange GTP for GDP on RABs" } ], "reaction_participants": [], "function": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_796166.2", "annotation": "DENND5B Regulates Intestinal Triglyceride Absorption and Body Mass. Publication Status: Online-Only", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_796166.2", "id": "NP_796166.2", "database": "RefSeq" } ] }, { "url": "https://www.uniprot.org/uniprot/A2RSQ0#function", "annotation": "Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0#function", "id": "A2RSQ0", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "M0R5A9-1", "protein_name": "Uncharacterized protein", "sequence": { "length": 977, "sequence": "LLFCTDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEGSLHCSESATKLKNMVLKDLANDKKNGNVPTNNVSVYELLKGSETIARLQALAKRTGVTVGKIDFPASLSEKEKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTSREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDSRIEKMRLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSTTAQRRKERLRQNAEHIGLDSDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLIQFQDREEKQEHLTDSPVALGPERRKSDSGVMLPTLRVSLIQDMRYFKQMSQILADFSSVRAYAVMHLVKGLPSTHEQVLLPAEPAHWKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTSASDEDLGKQCRTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFESTDQILDNEDDMLIQKPSCKTFCHYVNAVNTAPRNIGKDGKFQILVCLGTRESPAPQWIPLLAECPADHPMYEENALRDHMTVQFLIRILQTIQDFTIVLEGSKSKEVDV" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A2RSQ0/", "id": "A2RSQ0", "database": "OMA" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "gene_name": "Dennd5b", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q6ZUT9-1", "protein_name": "DENN domain-containing protein 5B", "sequence": { "length": 1274, "sequence": "MSGSCAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQTDNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEHYSSVYASSSCSMDSLASSLDEGDTTSLLKLQRYNSYDISRDTLYVSKSICLITPLPFMQACKKFLIQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPSELPLSDYPLREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLVQFGIPPEGSLHCSESTSKLKNMVLKDLVNDKKNGNVCTNNISMYELLKGNETIARLQALAKRTGVAVEKMDLSASLGEKDKDLKLHCEEAELRDYQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDTRIDKIRLYNVRAPTLRTSIYQKCSTLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTSNNRWVSRSATAQRRKERLRQHSEHVGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNCKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLIQFQDREEKQEHLAESPVALGPERRKSDSGVMLPTLRVSLIQDMRHIQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERILIGELMTSASDEDLVKQCRTPPQQKSPTTARRLSITSLTGKNNKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKVVAYFETTDQILDNEDDVLIQKSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDRLLPQWIPLLAECPAITRMYEESALLRDRMTVNSLIRILQTIQDFTIVLEGSLIKGVDV" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/44911", "id": "44911", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "DENND5B", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_796166.2", "ac": "NP_796166.2", "name": "DENN domain-containing protein 5B", "summary": "" }, "reaction_enzymes": [], "site_annotation": [ { "end_pos": 441, "annotation": "n_glycosylation_sequon", "start_pos": 439 }, { "end_pos": 770, "annotation": "n_glycosylation_sequon", "start_pos": 768 }, { "end_pos": 857, "annotation": "n_glycosylation_sequon", "start_pos": 855 } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000030313", "id": "ENSMUSG00000030313", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/320560", "id": "320560", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001024", "id": "IPR001024", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "id": "IPR001194", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "id": "IPR004012", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "id": "IPR005112", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "id": "IPR005113", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036392", "id": "IPR036392", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "id": "IPR037213", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "id": "IPR037516", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "id": "IPR043153", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:320560", "id": "mmu:320560", "database": "KEGG Pathway" }, { "url": "http://www.informatics.jax.org/marker/MGI:2444273", "id": "2444273", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/HKAVTSQ/", "id": "HKAVTSQ", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=53600at2759", "id": "53600at2759", "database": "OrthoDB" }, { "url": "http://pfam.xfam.org/family/PF01477", "id": "PF01477", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF02141", "id": "PF02141", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF02759", "id": "PF02759", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF03455", "id": "PF03455", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF03456", "id": "PF03456", "database": "Pfam" }, { "url": "http://purl.obolibrary.org/obo/PR_PR_A2RSQ0", "id": "PR_A2RSQ0", "database": "PRO" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8876198", "id": "R-MMU-8876198", "database": "Reactome" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_796166", "id": "NP_796166", "database": "RefSeq" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_796166.2", "id": "NP_796166.2", "database": "RefSeq" }, { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/A2RSQ0-1", "id": "A2RSQ0-1", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/B8JKU3", "id": "B8JKU3", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/B8JKU3-1", "id": "B8JKU3-1", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/E9Q0R9", "id": "E9Q0R9", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/E9Q0R9-1", "id": "E9Q0R9-1", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [ { "residue": "Thr", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "start_pos": 1062, "end_pos": 1062, "kinase_uniprot_canonical_ac": "" }, { "residue": "Ser", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "start_pos": 1068, "end_pos": 1068, "kinase_uniprot_canonical_ac": "" }, { "residue": "Ser", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "start_pos": 1076, "end_pos": 1076, "kinase_uniprot_canonical_ac": "" }, { "residue": "Ser", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "start_pos": 1079, "end_pos": 1079, "kinase_uniprot_canonical_ac": "" }, { "residue": "Ser", "kinase_gene_name": "Atxn7l3b", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/17242355", "id": "17242355", "database": "PubMed" }, { "url": "https://www.ncbi.nlm.nih.gov/pubmed/21183079", "id": "21183079", "database": "PubMed" } ], "start_pos": 178, "end_pos": 178, "kinase_uniprot_canonical_ac": "Q3UD01-1" }, { "residue": "Ser", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "start_pos": 178, "end_pos": 178, "kinase_uniprot_canonical_ac": "" }, { "residue": "Ser", "kinase_gene_name": "Atxn7l3b", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/21183079", "id": "21183079", "database": "PubMed" } ], "start_pos": 49, "end_pos": 49, "kinase_uniprot_canonical_ac": "Q3UD01-1" }, { "residue": "Ser", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "start_pos": 49, "end_pos": 49, "kinase_uniprot_canonical_ac": "" }, { "residue": "Ser", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "id": "A2RSQ0", "database": "UniProtKB" } ], "start_pos": 822, "end_pos": 822, "kinase_uniprot_canonical_ac": "" } ], "mass": { "monoisotopic_mass": 144629.0, "chemical_mass": 144629.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A2RSQ0", "name": "Dennd5b", "locus": { "end_pos": 148988071, "strand": "-", "start_pos": 149101680, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000030313", "id": "ENSMUSG00000030313", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2RSQ0", "type": "synonym", "resource": "RefSeq", "name": "DENN domain-containing protein 5B" }, { "url": "https://www.uniprot.org/uniprot/A2RSQ0#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "DENN domain-containing protein 5B" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2RSQ0", "type": "synonym", "resource": "RefSeq", "name": "RAB6IP1-like protein" }, { "url": "https://www.uniprot.org/uniprot/A2RSQ0#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "Rab6IP1-like protein" } ] }