{
    "uniprot_canonical_ac": "A1L112-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A1L112-1|WDR55_RAT Isoform 1 of WD repeat-containing protein 55  OS=Rattus norvegicus OX=10116 GN=Wdr55 PE=2 SV=1 CANONICAL=A1L112-1", 
        "length": 384, 
        "sequence": "MDPTCQESPAEDSNNEEDLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGETKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHVLDVEQGQLERRISKAHSAPINSLLLVDENVLVTGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVALMKYGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEELALSHCGHFLASSGHDQRLKFWDMTQLRTVVVDDYRRRKKKGGPLRALSSKAWSTDDFFAGLREDEEEAKAPEEVSGESDDDSD"
    }, 
    "uniprot_id": "", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L112", 
                    "id": "A1L112", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L112", 
                                "id": "A1L112", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L112", 
                                "id": "A1L112", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L112", 
                                "id": "A1L112", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleolus", 
                        "id": "GO:0005730"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L112", 
                                "id": "A1L112", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 4, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L112", 
                                "id": "A1L112", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "rRNA processing", 
                        "id": "GO:0006364"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "publication": [], 
    "uniprot_ac": "A1L112", 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L112", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Ik"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L112", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "LRRG00133; RGD1305640"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L112", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Wdr55"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L112", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Wdr55"
        }
    ], 
    "reactions": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L112#A0A0G2K5G9-1", 
            "isoform_ac": "A0A0G2K5G9-1", 
            "locus": {
                "end_pos": 29588023, 
                "strand": "-", 
                "start_pos": 29602503, 
                "chromosome": "18", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000085470", 
                        "id": "ENSRNOT00000085470", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000073422", 
                        "id": "ENSRNOP00000073422", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2K5G9-1|WDR55_RAT Computationally mapped isoform of WD repeat-containing protein 55  OS=Rattus norvegicus OX=10116 GN=Wdr55 PE=2 SV=1 CANONICAL=A1L112-1", 
                "length": 559, 
                "sequence": "MPERDSEPFSNPLAPDGHDVDDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKSYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRERDRERDRERERERDREREREEEKKRHSYFEKPKVDDEPMDVDKGPGSAKELIKSINEKFAGSAGWEGTESHMLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIEKRKKMEADGVEVKRPKY"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L112#A1L112-1", 
            "isoform_ac": "A1L112-1", 
            "locus": {}, 
            "sequence": {
                "header": "sp|A1L112-1|WDR55_RAT Isoform 1 of WD repeat-containing protein 55  OS=Rattus norvegicus OX=10116 GN=Wdr55 PE=2 SV=1 CANONICAL=A1L112-1", 
                "length": 384, 
                "sequence": "MDPTCQESPAEDSNNEEDLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGETKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHVLDVEQGQLERRISKAHSAPINSLLLVDENVLVTGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVALMKYGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEELALSHCGHFLASSGHDQRLKFWDMTQLRTVVVDDYRRRKKKGGPLRALSSKAWSTDDFFAGLREDEEEAKAPEEVSGESDDDSD"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L112#Q6QI75-1", 
            "isoform_ac": "Q6QI75-1", 
            "locus": {
                "end_pos": 29591611, 
                "strand": "-", 
                "start_pos": 29608335, 
                "chromosome": "18", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000043271", 
                        "id": "ENSRNOT00000043271", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000044213", 
                        "id": "ENSRNOP00000044213", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|Q6QI75-1|WDR55_RAT Computationally mapped isoform of WD repeat-containing protein 55  OS=Rattus norvegicus OX=10116 GN=Wdr55 PE=2 SV=1 CANONICAL=A1L112-1", 
                "length": 872, 
                "sequence": "MPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKSYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRERDRERDRERERERDREREREEEKKRHSYFEKPKVDDEHMLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIEKRKKMEADGALPIRPTRGSNYLGHAPILVVCSPARVDPMDPTCQESPAEDSNNEEDLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGETKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHVLDVEQGQLERRISKAHSAPINSLLLVDENVLVTGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVALMKYGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEELALSHCGHFLASSGHDQRLKFWDMTQLRTVVVDDYRRRKKKGGPLRALSSKAWSTDDFFAGLREDEEEAKAPEEVSGESDDDSD"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:307494", 
            "resource": "KEGG Pathway", 
            "id": "rno:307494", 
            "name": ""
        }
    ], 
    "reaction_participants": [], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L112#function", 
            "annotation": "Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis (By similarity).", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L112#function", 
                    "id": "A1L112", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9CX97-1", 
            "protein_name": "WD repeat-containing protein 55", 
            "sequence": {
                "length": 388, 
                "sequence": "MDPTCEESPAEDSNNEEEDLDSTKAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQEGETKELWSSGHHLKSCRAVVFSEDGQKLVTVSKDKAIHILDVEQGQLERRISKAHSAPINSVLLVDENALVTGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRRRFELLSEPQSGDLTSVALMKYGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCIVPVTENLLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEALALSHCGHFLASSGHDQRLKFWDMTQLRTVVVDDYRRRKKKGGPLRALSSKAWSTDDFFAGLREDEEDAKAPEEVVRESDDDDDDSD"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/9789", 
                    "id": "9789", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Wdr55", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q9H6Y2-1", 
            "protein_name": "WD repeat-containing protein 55", 
            "sequence": {
                "length": 383, 
                "sequence": "MDRTCEERPAEDGSDEEDPDSMEAPTRIRDTPEDIVLEAPASGLAFHPARDLLAAGDVDGDVFVFSYSCQEGETKELWSSGHHLKACRAVAFSEDGQKLITVSKDKAIHVLDVEQGQLERRVSKAHGAPINSLLLVDENVLATGDDTGGICLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGIFNIKRRRFELLSEPQSGDLTSVTLMKWGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTESLLCTGSTDGVIRAVNILPNRVVGSVGQHTGEPVEELALSHCGRFLASSGHDQRLKFWDMAQLRAVVVDDYRRRKKKGGPLRALSSKTWSTDDFFAGLREEGEDSMAQEEKEETGDDSD"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/9789", 
                    "id": "9789", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "WDR55", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017932.1", 
        "ac": "NP_001017932.1", 
        "name": "WD repeat-containing protein 55", 
        "summary": ""
    }, 
    "reaction_enzymes": [], 
    "site_annotation": [], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000017251", 
            "id": "ENSRNOG00000017251", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/307494", 
            "id": "307494", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", 
            "id": "IPR001680", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012492", 
            "id": "IPR012492", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012916", 
            "id": "IPR012916", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", 
            "id": "IPR015943", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017422", 
            "id": "IPR017422", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017986", 
            "id": "IPR017986", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", 
            "id": "IPR019775", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR024977", 
            "id": "IPR024977", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", 
            "id": "IPR036322", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039896", 
            "id": "IPR039896", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:307494", 
            "id": "rno:307494", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/PDMKSGI/", 
            "id": "PDMKSGI", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1173229at2759", 
            "id": "1173229at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12765", 
            "id": "PTHR12765", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00400", 
            "id": "PF00400", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF07807", 
            "id": "PF07807", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF07808", 
            "id": "PF07808", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF12894", 
            "id": "PF12894", 
            "database": "Pfam"
        }, 
        {
            "url": "http://purl.obolibrary.org/obo/PR_PR_A1L112", 
            "id": "PR_A1L112", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017932", 
            "id": "NP_001017932", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001017932.1", 
            "id": "NP_001017932.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1305640", 
            "id": "1305640", 
            "database": "RGD"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1359352", 
            "id": "1359352", 
            "database": "RGD"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K5G9", 
            "id": "A0A0G2K5G9", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K5G9-1", 
            "id": "A0A0G2K5G9-1", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L112", 
            "id": "A1L112", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L112-1", 
            "id": "A1L112-1", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/Q6QI75", 
            "id": "Q6QI75", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/Q6QI75-1", 
            "id": "Q6QI75-1", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [
        {
            "residue": "Ser", 
            "kinase_gene_name": "", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L112", 
                    "id": "A1L112", 
                    "database": "UniProtKB"
                }
            ], 
            "start_pos": 354, 
            "end_pos": 354, 
            "kinase_uniprot_canonical_ac": ""
        }, 
        {
            "residue": "Ser", 
            "kinase_gene_name": "", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L112", 
                    "id": "A1L112", 
                    "database": "UniProtKB"
                }
            ], 
            "start_pos": 383, 
            "end_pos": 383, 
            "kinase_uniprot_canonical_ac": ""
        }
    ], 
    "mass": {
        "monoisotopic_mass": 42142.0, 
        "chemical_mass": 42142.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L112", 
            "name": "Wdr55", 
            "locus": {
                "end_pos": 29608338, 
                "strand": "+", 
                "start_pos": 29587901, 
                "chromosome": "18", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000017251", 
                        "id": "ENSRNOG00000017251", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L112#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "LRRG00133"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L112#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Protein Red"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L112", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "WD repeat-containing protein 55"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L112#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "WD repeat-containing protein 55"
        }
    ]
}