{ "uniprot_canonical_ac": "A0A5F8MPH8-1", "ptm_annotation": [], "sequence": { "header": "tr|A0A5F8MPH8-1|A0A5F8MPH8_MOUSE Isoform 1 of Tenascin XB OS=Mus musculus OX=10090 GN=Tnxb PE=1 SV=1 CANONICAL=A0A5F8MPH8-1", "length": 4356, "sequence": "MAAQCTPSILTILVLLGLARAGPFSPRSNVTLPAPRPPPKPGGPSSQLYEHTVEGGEKQVVFTHRINLPPSAGCGCPPGSEPPVPASEVQALRVRLEILEELVKGLKEHCTGGCCPTAAQAGTGQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSSPPSKSCPEDCNDQGRCVRGRCVCFPGYSGPSCSWPSCPGDCQGRGRCVKGVCVCRAGFSGPDCSQRSCPRNCNQRGRCEEGRCVCDPGYSGEDCGVRSCPRGCSQRGRCENGLCVCNPGYSGEDCGVRNCPRGCSQRGRCEDGRCVCDPGYSGEDCSMRTCPWDCGDGGRCVDGRCVCWPGYSGEDCSTRTCPRDCRGRGRCEDGECICDAGYSGDDCGVRSCPGDCNQRGHCEDGRCVCWPGYTGADCSTRACPRDCRGRGRCEDGVCVCHAGYSGEDCGVRSCPGDCRGRGNCESGRCVCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGHCENGVCVCAVGYSGDDCSTRSCPSDCRGRGQCLNGLCECDEGYSGEDCGIRRCPRDCSQHGVCQDGLCMCHAGYAGEDCSIRTCPADCRRRGRCEDGRCVCNPGYTGPACATRTCPADCRGRGRCVQGVCMCYVGYSGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRSRGECIQGRCVCQEGYAGDDCGEEIPAIQNMRMHLLEETTVRTEWTRAPGPVDAYEIQFIPMTEGVSPPFTARVPSSASAYDQRGLAPGQDYQVTVRALRGTSWGPPASKTITTMIDGPQDLRVVAVTPTTLDLSWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADRTQLTDLMPGVEYVVTVTAERGHAVSYPASIRANTAPGHYSYPEVRPPAPPPNPRPRPRWPSRPLPSPETDEKEWHLRPRLPQPPRRPWGNLTTELSRFRGTVQDLEHHLRTHGYPLRANQTYASVARYIHEFLKRHQTAGAPASQPRHPHPTTSPTQNTRKRDSEQGAVGPASDGAHPVTTARHPKPEVLGSAADGSLIVSLDGLRGQFERVVLRWRPLLPAKGPSGELTVDGSERTVRLPNLRPGTTYHVEVHGVRAGQTSKSYAFITTTTTTTTGSLPSGLLEATDEPPPSGPSTTQGAQAPILILEHHPLGELKVLGRDKAGRLSVAWTAQPDSFAHFQLRMQVAEGPWAHEELLPGDVQQALVPPPPPGAPYKLFLHGITPGGKISVPITYQGIMDRAQEQPGKPSVQPRLGELTVTGLTSDSLLLHWTVPEGEFDSFLIQYKDKDGPQAISVEGPQRSTPISGLEPGRKYKFILYGLIGKKRHGPLMAEAKILIQSDPDPGSPPRLGELWVTDPTPHSLHLSWTVLGGQFDSFVVQYRDKEGQPRVVPVEGPDRSVVISPLDPNRKYRFTLFGIANKKRYGPLTADGTTAAETKEESSEPPRLGELTVTGVTPDSLRLSWTVARGPFDSFVILYKDAQGQPQSVPIEGDENEVTVPGLESNRKYKMNLYGLRGRQRVGPVSVVAKTAPPDVVDQPLSPPEPSTEAPEPPEKPLLRELIVTDTTPNSLSLSWTVSEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKSSDGRPQVMRVGGQEREVIVRDLDPGHKYKMNLYGLHEGHRVGPVSTVGTTDKQPEEKPPLEPRLEELTVTGVTPNSVSLSWIVPEGQFDSFVVQYQDRDGQPREVPLTAEQREVTVLDLDPARIYKMNFYGLHGRRRVGPLSVSAMTAPAPATEASKLLPEPRLGELTVTDVTPDSVGLLWTVPEGEFDSFTVQYKDRDGQPHVVSVAADLREVTIPGLEPSRKYKFLLFGVQDGKRRSQVSVEAKTATHDDTSPGAPPRLGELWVTDPTTDSLRLSWTVPEGHFDSFVVQFKDKSGPRVVPVKGQERTATITALDAGRKYRFLLYGLLGRKRFGPLTAEGITEPTNAADHTKSRLGEELRVTGVTQNSVDLSWTVSEGQFDSFVVQYKDRDGQSQVVPVDGSHREVRVSGLDPGRRYKLLLYGLRDSKRVGPLSVIAVTDPRETTEAWTEVPTTSTPAAVPRLGELRVEEATPHSLHLSWVVTEGEFNSFEVQYTDRDGQLRVASTEGDQTDITLTGLESNHRYLITLYGFHDGQPVGSAQIEALTVPWEEEEEEEESTEPPTMTPEPRPQLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKLNLYGIHSGQRFGPVSTVGVTAAVEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTDPKEEPTDASSLKPRLEELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPRTEAPEPTEAPEPTEEPRLGELTVTGSSPDSLSLSWTIPKGDFDSFTVQYKDSDGRPQVIRVRGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTIGVTAPEEEALTTQAVPTTTPEPPPKKPHLGELTVTDATPDSLSLSWTVPEEQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSVVGVTAAEEEPPSPEPSTEAPEPTEAPEPTEEPLLGELTVTGSSPDSLILSWTIPKGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTEEEATTTQAEPIVTTEPPPKKPHLGVLTVTDATPDSLSLSWTVPEAHFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPSTEAPESTEEPLLGELTVTGSSPDSLSLSWTVPQGEFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGMTEKEALTTQVVPTTTPEPPPKKPHLGELTVTDATSDSLSLSWTVPEGQFEQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRFGPVSTVGVTTAVEEPPSPTEPSIEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTASLTTEPPIEPRLGELAAVEVTSSTVHLSWTVAQGPFDSFLVQYKDTQGQPQMVPVSGDLGEVTVSGLEPARKYKFLLFGLKDGKRHGPVSTEAKTVSDAKLLPRLGELTVTDTTQNSVGLSWTVPEGEFDSFLVQYKNRGGQVQVVPAAADQREVTISSLEPNRKYRFLLFGLIGLKRLGPVSVEGTTAPVEKTPQPRLGELSVTEETSDSMHLSWSVAQGPFDSFLVQYKDRDGQLQTVSLAADQREVTIEGLQPGRKYKFLLYGLTGGKRLGPISALGVTASEVDISAPDHTEPPHAPGLGTLAVTEATPDSLRLSWAVARGPFDSFVVQYQDTENETQALLVDGDQDKVLISGLEPKTSYKFFLYGLREGTRHGPVSVEGTTDPVPAGQGPGDPGPRLSQLSVSDVTTSSLRLNWEAPLGAFDSFLLRFGVPLLSTLEQNPRTLQQRELMVPGVRRSAMLRDLRPGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSDIGETSAKVKWVPPTSRVDSFKISYQLADGGEPQSVQVDGRTQTQILQGLIPDTRYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTDGSALLHWKPPHKPVDKYDVEVESPGAPPLQASAPGSAVDYPLTDLALDTNYTATVRGLRGPNFTSPASITFTTGLKPPQDLEAKEVTPRTALLTWTEPEVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSAQLRAIWGESLTPPVLTSFTTGGLRIPFPRDCGEELKNGPSASKTTTIFLNGNRERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISGEFWLGNEALHSLTQAGDYSLRVDLRAGKEAVFAQYDFFRVDSAKENYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNNLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFQVPTRGT" }, "uniprot_id": "", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "pmid": "7512972", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "heparin binding", "id": "GO:0008201" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "pmid": "15242785", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "collagen binding", "id": "GO:0005518" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098633", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "collagen fibril binding", "id": "GO:0098633" } ], "total": 3, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "pmid": "8856503", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "extracellular region", "id": "GO:0005576" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "pmid": "7512972", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "extracellular space", "id": "GO:0005615" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "pmid": "24563484", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "extracellular matrix", "id": "GO:0031012" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "pmid": "7512972", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "extracellular matrix", "id": "GO:0031012" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062023", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "collagen-containing extracellular matrix", "id": "GO:0062023" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062023", "pmid": "28071719", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "collagen-containing extracellular matrix", "id": "GO:0062023" } ], "total": 6, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "pmid": "15298681", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "lipid metabolic process", "id": "GO:0006629" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "pmid": "15298681", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "fatty acid metabolic process", "id": "GO:0006631" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006641", "pmid": "15298681", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "triglyceride metabolic process", "id": "GO:0006641" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "pmid": "15242785", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "extracellular matrix organization", "id": "GO:0030198" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "pmid": "12419962", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "cell-matrix adhesion", "id": "GO:0007160" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "pmid": "12419962", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "cell-cell adhesion", "id": "GO:0098609" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "pmid": "11925569", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "collagen fibril organization", "id": "GO:0030199" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "pmid": "15194424", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "collagen fibril organization", "id": "GO:0030199" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043506", "pmid": "15212943", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "regulation of JUN kinase activity", "id": "GO:0043506" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048251", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "elastic fiber assembly", "id": "GO:0048251" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032963", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" } ], "name": "collagen metabolic process", "id": "GO:0032963" } ], "total": 11, "name": "Biological Process" } ] }, "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/14656967", "type": "PubMed", "id": "14656967" } ], "title": "Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.", "journal": "Genome Res.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/O35452", "id": "O35452", "database": "UniProtKB" } ], "authors": "Aguado B., Hood L., Madan A., Qin S., Rowen L., Xie T., Ahearn M.E., Campbell R.D.", "date": "2003" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/30605228", "type": "PubMed", "id": "30605228" } ], "title": "A novel role for the extracellular matrix glycoprotein-Tenascin-X in gastric function.", "journal": "The Journal of physiology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_112453.2", "id": "NP_112453.2", "database": "RefSeq" } ], "authors": "Aktar R, Peiris M, Fikree A, Eaton S, Kritas S, Kentish SJ, Araujo EJA, Bacarin C, Page AJ, Voermans NC, Aziz Q, Blackshaw LA", "date": "2019" } ], "uniprot_ac": "A0A5F8MPH8", "gene_names": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "type": "synonym", "resource": "UniProtKB", "name": "TNX" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A5F8MPH8", "type": "synonym", "resource": "RefSeq", "name": "Tn; TN-MH; Tn-mhc; Tnx" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A5F8MPH8", "type": "synonym", "resource": "RefSeq", "name": "Tnxb" }, { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "type": "recommended", "resource": "UniProtKB", "name": "Tnxb" } ], "reactions": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8#A0A571BG59-1", "isoform_ac": "A0A571BG59-1", "locus": { "end_pos": 34670535, "strand": "-", "start_pos": 34719624, "chromosome": "17", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000238305", "id": "ENSMUST00000238305", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000158703", "id": "ENSMUSP00000158703", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A571BG59-1|A0A5F8MPH8_MOUSE Computationally mapped isoform of Tenascin XB OS=Mus musculus OX=10090 GN=Tnxb PE=1 SV=1 CANONICAL=A0A5F8MPH8-1", "length": 4114, "sequence": "MAAQCTPSILTILVLLGLARAGPFSPRSNVTLPAPRPPPKPGGPSSQLYEHTVEGGEKQVVFTHRINLPPSAGCGCPPGSEPPVPASEVQALRVRLEILEELVKGLKEHCTGGCCPTAAQAGTGQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSSPPSKSCPEDCNDQGRCVRGRCVCFPGYSGPSCSWPSCPGDCQGRGRCVKGVCVCRAGFSGPDCSQRSCPRNCNQRGRCEEGRCVCDPGYSGEDCGVRSCPRGCSQRGRCENGLCVCNPGYSGEDCGVRNCPRGCSQRGRCEDGRCVCDPGYSGEDCSMRTCPWDCGDGGRCVDGRCVCWPGYSGEDCSTRTCPRDCRGRGRCEDGECICDAGYSGDDCGVRSCPGDCNQRGHCEDGRCVCWPGYTGADCSTRACPRDCRGRGRCEDGVCVCHAGYSGEDCGVRSCPGDCRGRGNCESGRCVCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGHCENGVCVCAVGYSGDDCSTRSCPSDCRGRGQCLNGLCECDEGYSGEDCGIRRCPRDCSQHGVCQDGLCMCHAGYAGEDCSIRTCPADCRRRGRCEDGRCVCNPGYTGPACATRTCPADCRGRGRCVQGVCMCYVGYSGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRSRGECIQGRCVCQEGYAGDDCGEEIPAIQNMRMHLLEETTVRTEWTRAPGPVDAYEIQFIPMTEGVSPPFTARVPSSASAYDQRGLAPGQDYQVTVRALRGTSWGPPASKTITTMIDGPQDLRVVAVTPTTLDLSWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADRTQLTDLMPGVEYVVTVTAERGHAVSYPASIRANTGSLPSGLLEATDEPPPSGPSTTQGAQAPILILEHHPLGELKVLGRDKAGRLSVAWTAQPDSFAHFQLRMQVAEGPWAHEELLPGDVQQALVPPPPPGAPYKLFLHGITPGGKISVPITYQGIMDRAQEQPGKPSVQPRLGELTVTGLTSDSLLLHWTVPEGEFDSFLIQYKDKDGPQAISVEGPQRSTPISGLEPGRKYKFILYGLIGKKRHGPLMAEAKILIQSDPDPGSPPRLGELWVTDPTPHSLHLSWTVLGGQFDSFVVQYRDKEGQPRVVPVEGPDRSVVISPLDPNRKYRFTLFGIANKKRYGPLTADGTTAAETKEESSEPPRLGELTVTGVTPDSLRLSWTVARGPFDSFVILYKDAQGQPQSVPIEGDENEVTVPGLESNRKYKMNLYGLRGRQRVGPVSVVAKTAPPDVVDQPLSPPEPSTEAPEPPEKPLLRELIVTDTTPNSLSLSWTVSEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKSSDGRPQVMRVGGQEREVIVRDLDPGHKYKMNLYGLHEGHRVGPVSTVGTTDKQPEEKPPLEPRLEELTVTGVTPNSVSLSWIVPEGQFDSFVVQYQDRDGQPREVPLTAEQREVTVLDLDPARIYKMNFYGLHGRRRVGPLSVSAMTAPAPATEASKLLPEPRLGELTVTDVTPDSVGLLWTVPEGEFDSFTVQYKDRDGQPHVVSVAADLREVTIPGLEPSRKYKFLLFGVQDGKRRSQVSVEAKTATHDDTSPGAPPRLGELWVTDPTTDSLRLSWTVPEGHFDSFVVQFKDKSGPRVVPVKGQERTATITALDAGRKYRFLLYGLLGRKRFGPLTAEGITEPTNAADHTKSRLGEELRVTGVTQNSVDLSWTVSEGQFDSFVVQYKDRDGQSQVVPVDGSHREVRVSGLDPGRRYKLLLYGLRDSKRVGPLSVIAVTDPRETTEAWTEVPTTSTPAAVPRLGELRVEEATPHSLHLSWVVTEGEFNSFEVQYTDRDGQLRVASTEGDQTDITLTGLESNHRYLITLYGFHDGQPVGSAQIEALTVPWEEEEEEEESTEPPTMTPEPRPQLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKLNLYGIHSGQRFGPVSTVGVTAAVEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTDPKEEPTDASSLKPRLEELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPRTEAPEPTEAPEPTEEPRLGELTVTGSSPDSLSLSWTIPKGDFDSFTVQYKDSDGRPQVIRVRGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTIGVTAPEEEALTTQAVPTTTPEPPPKKPHLGELTVTDATPDSLSLSWTVPEEQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSVVGVTAAEEEPPSPEPSTEAPEPTEAPEPTEEPLLGELTVTGSSPDSLILSWTIPKGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTEEEATTTQAEPIVTTEPPPKKPHLGVLTVTDATPDSLSLSWTVPEAHFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPSTEAPESTEEPLLGELTVTGSSPDSLSLSWTVPQGEFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGMTEKEALTTQVVPTTTPEPPPKKPHLGELTVTDATSDSLSLSWTVPEGQFEQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRFGPVSTVGVTTAVEEPPSPTEPSIEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTASLTTEPPIEPRLGELAAVEVTSSTVHLSWTVAQGPFDSFLVQYKDTQGQPQMVPVSGDLGEVTVSGLEPARKYKFLLFGLKDGKRHGPVSTEAKTVSDAKLLPRLGELTVTDTTQNSVGLSWTVPEGEFDSFLVQYKNRGGQVQVVPAAADQREVTISSLEPNRKYRFLLFGLIGLKRLGPVSVEGTTAPVEKTPQPRLGELSVTEETSDSMHLSWSVAQGPFDSFLVQYKDRDGQLQTVSLAADQREVTIEGLQPGRKYKFLLYGLTGGKRLGPISALGVTASEVDISAPDHTEPPHAPGLGTLAVTEATPDSLRLSWAVARGPFDSFVVQYQDTENETQALLVDGDQDKVLISGLEPKTSYKFFLYGLREGTRHGPVSVEGTTDPVPAGQGPGDPGPRLSQLSVSDVTTSSLRLNWEAPLGAFDSFLLRFGVPLLSTLEQNPRTLQQRELMVPGVRRSAMLRDLRPGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSDIGETSAKVKWVPPTSRVDSFKISYQLADGGEPQSVQVDGRTQTQILQGLIPDTRYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTDGSALLHWKPPHKPVDKYDVEVESPGAPPLQASAPGSAVDYPLTDLALDTNYTATVRGLRGPNFTSPASITFTTGLKPPQDLEAKEVTPRTALLTWTEPEVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSAQLRAIWGESLTPPVLTSFTTGGLRIPFPRDCGEELKNGPSASKTTTIFLNGNRERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISGEFWLGNEALHSLTQAGDYSLRVDLRAGKEAVFAQYDFFRVDSAKENYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNNLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFQVPTRGT" } }, { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8#A0A5F8MPH8-1", "isoform_ac": "A0A5F8MPH8-1", "locus": { "end_pos": 34670535, "strand": "-", "start_pos": 34719624, "chromosome": "17", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000238967", "id": "ENSMUST00000238967", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000158977", "id": "ENSMUSP00000158977", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A5F8MPH8-1|A0A5F8MPH8_MOUSE Isoform 1 of Tenascin XB OS=Mus musculus OX=10090 GN=Tnxb PE=1 SV=1 CANONICAL=A0A5F8MPH8-1", "length": 4356, "sequence": "MAAQCTPSILTILVLLGLARAGPFSPRSNVTLPAPRPPPKPGGPSSQLYEHTVEGGEKQVVFTHRINLPPSAGCGCPPGSEPPVPASEVQALRVRLEILEELVKGLKEHCTGGCCPTAAQAGTGQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSSPPSKSCPEDCNDQGRCVRGRCVCFPGYSGPSCSWPSCPGDCQGRGRCVKGVCVCRAGFSGPDCSQRSCPRNCNQRGRCEEGRCVCDPGYSGEDCGVRSCPRGCSQRGRCENGLCVCNPGYSGEDCGVRNCPRGCSQRGRCEDGRCVCDPGYSGEDCSMRTCPWDCGDGGRCVDGRCVCWPGYSGEDCSTRTCPRDCRGRGRCEDGECICDAGYSGDDCGVRSCPGDCNQRGHCEDGRCVCWPGYTGADCSTRACPRDCRGRGRCEDGVCVCHAGYSGEDCGVRSCPGDCRGRGNCESGRCVCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGHCENGVCVCAVGYSGDDCSTRSCPSDCRGRGQCLNGLCECDEGYSGEDCGIRRCPRDCSQHGVCQDGLCMCHAGYAGEDCSIRTCPADCRRRGRCEDGRCVCNPGYTGPACATRTCPADCRGRGRCVQGVCMCYVGYSGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRSRGECIQGRCVCQEGYAGDDCGEEIPAIQNMRMHLLEETTVRTEWTRAPGPVDAYEIQFIPMTEGVSPPFTARVPSSASAYDQRGLAPGQDYQVTVRALRGTSWGPPASKTITTMIDGPQDLRVVAVTPTTLDLSWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADRTQLTDLMPGVEYVVTVTAERGHAVSYPASIRANTAPGHYSYPEVRPPAPPPNPRPRPRWPSRPLPSPETDEKEWHLRPRLPQPPRRPWGNLTTELSRFRGTVQDLEHHLRTHGYPLRANQTYASVARYIHEFLKRHQTAGAPASQPRHPHPTTSPTQNTRKRDSEQGAVGPASDGAHPVTTARHPKPEVLGSAADGSLIVSLDGLRGQFERVVLRWRPLLPAKGPSGELTVDGSERTVRLPNLRPGTTYHVEVHGVRAGQTSKSYAFITTTTTTTTGSLPSGLLEATDEPPPSGPSTTQGAQAPILILEHHPLGELKVLGRDKAGRLSVAWTAQPDSFAHFQLRMQVAEGPWAHEELLPGDVQQALVPPPPPGAPYKLFLHGITPGGKISVPITYQGIMDRAQEQPGKPSVQPRLGELTVTGLTSDSLLLHWTVPEGEFDSFLIQYKDKDGPQAISVEGPQRSTPISGLEPGRKYKFILYGLIGKKRHGPLMAEAKILIQSDPDPGSPPRLGELWVTDPTPHSLHLSWTVLGGQFDSFVVQYRDKEGQPRVVPVEGPDRSVVISPLDPNRKYRFTLFGIANKKRYGPLTADGTTAAETKEESSEPPRLGELTVTGVTPDSLRLSWTVARGPFDSFVILYKDAQGQPQSVPIEGDENEVTVPGLESNRKYKMNLYGLRGRQRVGPVSVVAKTAPPDVVDQPLSPPEPSTEAPEPPEKPLLRELIVTDTTPNSLSLSWTVSEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKSSDGRPQVMRVGGQEREVIVRDLDPGHKYKMNLYGLHEGHRVGPVSTVGTTDKQPEEKPPLEPRLEELTVTGVTPNSVSLSWIVPEGQFDSFVVQYQDRDGQPREVPLTAEQREVTVLDLDPARIYKMNFYGLHGRRRVGPLSVSAMTAPAPATEASKLLPEPRLGELTVTDVTPDSVGLLWTVPEGEFDSFTVQYKDRDGQPHVVSVAADLREVTIPGLEPSRKYKFLLFGVQDGKRRSQVSVEAKTATHDDTSPGAPPRLGELWVTDPTTDSLRLSWTVPEGHFDSFVVQFKDKSGPRVVPVKGQERTATITALDAGRKYRFLLYGLLGRKRFGPLTAEGITEPTNAADHTKSRLGEELRVTGVTQNSVDLSWTVSEGQFDSFVVQYKDRDGQSQVVPVDGSHREVRVSGLDPGRRYKLLLYGLRDSKRVGPLSVIAVTDPRETTEAWTEVPTTSTPAAVPRLGELRVEEATPHSLHLSWVVTEGEFNSFEVQYTDRDGQLRVASTEGDQTDITLTGLESNHRYLITLYGFHDGQPVGSAQIEALTVPWEEEEEEEESTEPPTMTPEPRPQLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKLNLYGIHSGQRFGPVSTVGVTAAVEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTDPKEEPTDASSLKPRLEELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPRTEAPEPTEAPEPTEEPRLGELTVTGSSPDSLSLSWTIPKGDFDSFTVQYKDSDGRPQVIRVRGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTIGVTAPEEEALTTQAVPTTTPEPPPKKPHLGELTVTDATPDSLSLSWTVPEEQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSVVGVTAAEEEPPSPEPSTEAPEPTEAPEPTEEPLLGELTVTGSSPDSLILSWTIPKGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTEEEATTTQAEPIVTTEPPPKKPHLGVLTVTDATPDSLSLSWTVPEAHFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPSTEAPESTEEPLLGELTVTGSSPDSLSLSWTVPQGEFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGMTEKEALTTQVVPTTTPEPPPKKPHLGELTVTDATSDSLSLSWTVPEGQFEQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRFGPVSTVGVTTAVEEPPSPTEPSIEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTASLTTEPPIEPRLGELAAVEVTSSTVHLSWTVAQGPFDSFLVQYKDTQGQPQMVPVSGDLGEVTVSGLEPARKYKFLLFGLKDGKRHGPVSTEAKTVSDAKLLPRLGELTVTDTTQNSVGLSWTVPEGEFDSFLVQYKNRGGQVQVVPAAADQREVTISSLEPNRKYRFLLFGLIGLKRLGPVSVEGTTAPVEKTPQPRLGELSVTEETSDSMHLSWSVAQGPFDSFLVQYKDRDGQLQTVSLAADQREVTIEGLQPGRKYKFLLYGLTGGKRLGPISALGVTASEVDISAPDHTEPPHAPGLGTLAVTEATPDSLRLSWAVARGPFDSFVVQYQDTENETQALLVDGDQDKVLISGLEPKTSYKFFLYGLREGTRHGPVSVEGTTDPVPAGQGPGDPGPRLSQLSVSDVTTSSLRLNWEAPLGAFDSFLLRFGVPLLSTLEQNPRTLQQRELMVPGVRRSAMLRDLRPGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSDIGETSAKVKWVPPTSRVDSFKISYQLADGGEPQSVQVDGRTQTQILQGLIPDTRYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTDGSALLHWKPPHKPVDKYDVEVESPGAPPLQASAPGSAVDYPLTDLALDTNYTATVRGLRGPNFTSPASITFTTGLKPPQDLEAKEVTPRTALLTWTEPEVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSAQLRAIWGESLTPPVLTSFTTGGLRIPFPRDCGEELKNGPSASKTTTIFLNGNRERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISGEFWLGNEALHSLTQAGDYSLRVDLRAGKEAVFAQYDFFRVDSAKENYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNNLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFQVPTRGT" } }, { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8#E9Q2T3-1", "isoform_ac": "E9Q2T3-1", "locus": { "end_pos": 34670535, "strand": "-", "start_pos": 34719624, "chromosome": "17", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000168533", "id": "ENSMUST00000168533", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000127487", "id": "ENSMUSP00000127487", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E9Q2T3-1|E9Q2T3_MOUSE Computationally mapped isoform of Tenascin XB OS=Mus musculus OX=10090 GN=Tnxb PE=1 SV=1 CANONICAL=A0A5F8MPH8-1", "length": 3126, "sequence": "MAAQCTPSILTILVLLGLARAGPFSPRSNVTLPAPRPPPKPGGPSSQLYEHTVEGGEKQVVFTHRINLPPSAGCGCPPGSEPPVPASEVQALRVRLEILEELVKGLKEHCTGGCCPTAAQAGTGQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSSPPSKSCPEDCNDQGRCVRGRCVCFPGYSGPSCSWPSCPGDCQGRGRCVKGVCVCRAGFSGPDCSQRSCPRNCNQRGRCEEGRCVCDPGYSGEDCGVRSCPRGCSQRGRCENGLCVCNPGYSGEDCGVRNCPRGCSQRGRCEDGRCVCDPGYSGEDCSMRTCPWDCGDGGRCVDGRCVCWPGYSGEDCSTRTCPRDCRGRGRCEDGECICDAGYSGDDCGVRSCPGDCNQRGHCEDGRCVCWPGYTGADCSTRACPRDCRGRGRCEDGVCVCHAGYSGEDCGVRSCPGDCRGRGNCESGRCVCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGHCENGVCVCAVGYSGDDCSTRSCPSDCRGRGQCLNGLCECDEGYSGEDCGIRRCPRDCSQHGVCQDGLCMCHAGYAGEDCSIRTCPADCRRRGRCEDGRCVCNPGYTGPACATRTCPADCRGRGRCVQGVCMCYVGYSGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRSRGECIQGRCVCQEGYAGDDCGEEIPAIQNMRMHLLEETTVRTEWTRAPGPVDAYEIQFIPMTEGVSPPFTARVPSSASAYDQRGLAPGQDYQVTVRALRGTSWGPPASKTITTMIDGPQDLRVVAVTPTTLDLSWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADRTQLTDLMPGVEYVVTVTAERGHAVSYPASIRANTDRAQEQPGKPSVQPRLGELTVTGLTSDSLLLHWTVPEGEFDSFLIQYKDKDGPQAISVEGPQRSTPISGLEPGRKYKFILYGLIGKKRHGPLMAEAKILIQSDPDPGSPPRLGELWVTDPTPHSLHLSWTVLGGQFDSFVVQYRDKEGQPRVVPVEGPDRSVVISPLDPNRKYRFTLFGIANKKRYGPLTADGTTAAETKEESSEPPRLGELTVTGVTPDSLRLSWTVARGPFDSFVILYKDAQGQPQSVPIEGDENEVTVPGLESNRKYKMNLYGLRGRQRVGPVSVVAKTAPPDVVDQPLSPPEPSTEAPEPPEKPLLRELIVTDTTPNSLSLSWTVSEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKSSDGRPQVMRVGGQEREVIVRDLDPGHKYKMNLYGLHEGHRVGPVSTVGTTDKQPEEKPPLEPRLEELTVTGVTPNSVSLSWIVPEGQFDSFVVQYQDRDGQPREVPLTAEQREVTVLDLDPARIYKMNFYGLHGRRRVGPLSVSAMTAPAPATEASKLLPEPRLGELTVTDVTPDSVGLLWTVPEGEFDSFTVQYKDRDGQPHVVSVAADLREVTIPGLEPSRKYKFLLFGVQDGKRRSQVSVEAKTATHDDTSPGAPPRLGELWVTDPTTDSLRLSWTVPEGHFDSFVVQFKDKSGPRVVPVKGQERTATITALDAGRKYRFLLYGLLGRKRFGPLTAEGITEPTNAADHTKSRLGEELRVTGVTQNSVDLSWTVSEGQFDSFVVQYKDRDGQSQVVPVDGSHREVRVSGLDPGRRYKLLLYGLRDSKRVGPLSVIAVTDPRETTEAWTEVPTTSTPAAVPRLGELRVEEATPHSLHLSWVVTEGEFNSFEVQYTDRDGQLRVASTEGDQTDITLTGLESNHRYLITLYGFHDGQPVGSAQIEALTVPWEEEEEEEESTEPPTMTPEPRPQLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKLNLYGIHSGQRFGPVSTVGVTAAVEEPPSPTEPSIEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTASLTTEPPIEPRLGELAAVEVTSSTVHLSWTVAQGPFDSFLVQYKDTQGQPQMVPVSGDLGEVTVSGLEPARKYKFLLFGLKDGKRHGPVSTEAKTVSDAKLLPRLGELTVTDTTQNSVGLSWTVPEGEFDSFLVQYKNRGGQVQVVPAAADQREVTISSLEPNRKYRFLLFGLIGLKRLGPVSVEGTTAPVEKTPQPRLGELSVTEETSDSMHLSWSVAQGPFDSFLVQYKDRDGQLQTVSLAADQREVTIEGLQPGRKYKFLLYGLTGGKRLGPISALGVTASEVDISAPDHTEPPHAPGLGTLAVTEATPDSLRLSWAVARGPFDSFVVQYQDTENETQALLVDGDQDKVLISGLEPKTSYKFFLYGLREGTRHGPVSVEGTTDPVPAGQGPGDPGPRLSQLSVSDVTTSSLRLNWEAPLGAFDSFLLRFGVPLLSTLEQNPRTLQQRELMVPGVRRSAMLRDLRPGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSDIGETSAKVKWVPPTSRVDSFKISYQLADGGEPQSVQVDGRTQTQILQGLIPDTRYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTDGSALLHWKPPHKPVDKYDVEVESPGAPPLQASAPGSAVDYPLTDLALDTNYTATVRGLRGPNFTSPASITFTTGLKPPQDLEAKEVTPRTALLTWTEPEVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSAQLRAIWGESLTPPVLTSFTTGGLRIPFPRDCGEELKNGPSASKTTTIFLNGNRERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISGEFWLGNEALHSLTQAGDYSLRVDLRAGKEAVFAQYDFFRVDSAKENYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNNLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFQVPTRGT" } }, { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8#O35452-1", "isoform_ac": "O35452-1", "locus": { "end_pos": 34670535, "strand": "-", "start_pos": 34719624, "chromosome": "17", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000087399", "id": "ENSMUST00000087399", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000084661", "id": "ENSMUSP00000084661", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|O35452-1|O35452_MOUSE Computationally mapped isoform of Tenascin XB OS=Mus musculus OX=10090 GN=Tnxb PE=1 SV=1 CANONICAL=A0A5F8MPH8-1", "length": 4006, "sequence": "MAAQCTPSILTILVLLGLARAGPFSPRSNVTLPAPRPPPKPGGPSSQLYEHTVEGGEKQVVFTHRINLPPSAGCGCPPGSEPPVPASEVQALRVRLEILEELVKGLKEHCTGGCCPTAAQAGTGQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDTKTPTSSPPSKSCPEDCNDQGRCVRGRCVCFPGYSGPSCSWPSCPGDCQGRGRCVKGVCVCRAGFSGPDCSQRSCPRNCNQRGRCEEGRCVCDPGYSGEDCGVRSCPRGCSQRGRCENGLCVCNPGYSGEDCGVRNCPRGCSQRGRCEDGRCVCDPGYSGEDCSMRTCPWDCGDGGRCVDGRCVCWPGYSGEDCSTRTCPRDCRGRGRCEDGECICDAGYSGDDCGVRSCPGDCNQRGHCEDGRCVCWPGYTGADCSTRACPRDCRGRGRCEDGVCVCHAGYSGEDCGVRSCPGDCRGRGNCESGRCVCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGHCENGVCVCAVGYSGDDCSTRSCPSDCRGRGQCLNGLCECDEGYSGEDCGIRRCPRDCSQHGVCQDGLCMCHAGYAGEDCSIRTCPADCRRRGRCEDGRCVCNPGYTGPACATRTCPADCRGRGRCVQGVCMCYVGYSGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRSRGECIQGRCVCQEGYAGDDCGEEIPAIQNMRMHLLEETTVRTEWTRAPGPVDAYEIQFIPMTEGVSPPFTARVPSSASAYDQRGLAPGQDYQVTVRALRGTSWGPPASKTITTMIDGPQDLRVVAVTPTTLDLSWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADRTQLTDLMPGVEYVVTVTAERGHAVSYPASIRANTGSLPSGLLEATDEPPPSGPSTTQGAQAPILILEHHPLGELKVLGRDKAGRLSVAWTAQPDSFAHFQLRMQVAEGPWAHEELLPGDVQQALVPPPPPGAPYKLFLHGITPGGKISVPITYQGIMDRAQEQPGKPSVQPRLGELTVTGLTSDSLLLHWTVPEGEFDSFLIQYKDKDGPQAISVEGPQRSTPISGLEPGRKYKFILYGLIGKKRHGPLMAEAKILIQSDPDPGSPPRLGELWVTDPTPHSLHLSWTVLGGQFDSFVVQYRDKEGQPRVVPVEGPDRSVVISPLDPNRKYRFTLFGIANKKRYGPLTADGTTAAETKEESSEPPRLGELTVTGVTPDSLRLSWTVARGPFDSFVILYKDAQGQPQSVPIEGDENEVTVPGLESNRKYKMNLYGLRGRQRVGPVSVVAKTAPPDVVDQPLSPPEPSTEAPEPPEKPLLRELIVTDTTPNSLSLSWTVSEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRVGPVSVVGVTAAEEEPPSPTEPSTEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKSSDGRPQVMRVGGQEREVIVRDLDPGHKYKMNLYGLHEGHRVGPVSTVGTTDKQPEEKPPLEPRLEELTVTGVTPNSVSLSWIVPEGQFDSFVVQYQDRDGQPREVPLTAEQREVTVLDLDPARIYKMNFYGLHGRRRVGPLSVSAMTAPAPATEASKLLPEPRLGELTVTDVTPDSVGLLWTVPEGEFDSFTVQYKDRDGQPHVVSVAADLREVTIPGLEPSRKYKFLLFGVQDGKRRSQVSVEAKTATHDDTSPGAPPRLGELWVTDPTTDSLRLSWTVPEGHFDSFVVQFKDKSGPRVVPVKGQERTATITALDAGRKYRFLLYGLLGRKRFGPLTAEGITEPTNAADHTKSRLGEELRVTGVTQNSVDLSWTVSEGQFDSFVVQYKDRDGQSQVVPVDGSHREVRVSGLDPGRRYKLLLYGLRDSKRVGPLSVIAVTDPRETTEAWTEVPTTSTPAAVPRLGELRVEEATPHSLHLSWVVTEGEFNSFEVQYTDRDGQLRVASTEGDQTDITLTGLESNHRYLITLYGFHDGQPVGSAQIEALTVPWEEEEEEEESTEPPTMTPEPRPQLGELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKLNLYGIHSGQRFGPVSTVGVTDPKEEPTDASSLKPRLEELTVTDATPDSLSLSWTVPEGQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPRTEAPEPTEAPEPTEEPRLGELTVTGSSPDSLSLSWTIPKGDFDSFTVQYKDSDGRPQVIRVRGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTIGVTAPEEEALTTQAVPTTTPEPPPKKPHLGELTVTDATPDSLSLSWTVPEEQFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSVVGVTAAEEEPPSPEPSTEAPEPTEAPEPTEEPLLGELTVTGSSPDSLILSWTIPKGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTEEEATTTQAEPIVTTEPPPKKPHLGVLTVTDATPDSLSLSWTVPEAHFDQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIYSGQRVGPVSAVGVTAAEEEPPSPTEPSTEAPESTEEPLLGELTVTGSSPDSLSLSWTVPQGEFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGMTEKEALTTQVVPTTTPEPPPKKPHLGELTVTDATSDSLSLSWTVPEGQFEQFVIQYKNGDGQPKVVRVPGHEDQVTISGLEPDHKYKMNLYGIHSGQRFGPVSTVGVTTAVEEPPSPTEPSIEAPEPTEEPLLGELTVTGSSPDSLSLSWTVPQGDFDSFTVQYKDSDGRPQVMRVGGQEREVIVRDLDPGRKYKMNLYGLHEGRRVGPVSTVGVTASLTTEPPIEPRLGELAAVEVTSSTVHLSWTVAQGPFDSFLVQYKDTQGQPQMVPVSGDLGEVTVSGLEPARKYKFLLFGLKDGKRHGPVSTEAKTVSDAKLLPRLGELTVTDTTQNSVGLSWTVPEGEFDSFLVQYKNRGGQVQVVPAAADQREVTISSLEPNRKYRFLLFGLIGLKRLGPVSVEGTTAPVEKTPQPRLGELSVTEETSDSMHLSWSVAQGPFDSFLVQYKDRDGQLQTVSLAADQREVTIEGLQPGRKYKFLLYGLTGGKRLGPISALGVTASEVDISAPDHTEPPHAPGLGTLAVTEATPDSLRLSWAVARGPFDSFVVQYQDTENETQALLVDGDQDKVLISGLEPKTSYKFFLYGLREGTRHGPVSVEGTTDPVPAGQGPGDPGPRLSQLSVSDVTTSSLRLNWEAPLGAFDSFLLRFGVPLLSTLEQNPRTLQQRELMVPGVRRSAMLRDLRPGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSDIGETSAKVKWVPPTSRVDSFKISYQLADGGEPQSVQVDGRTQTQILQGLIPDTRYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTDGSALLHWKPPHKPVDKYDVEVESPGAPPLQASAPGSAVDYPLTDLALDTNYTATVRGLRGPNFTSPASITFTTGLKPPQDLEAKEVTPRTALLTWTEPEVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSAQLRAIWGESLTPPVLTSFTTGGLRIPFPRDCGEELKNGPSASKTTTIFLNGNRERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISGEFWLGNEALHSLTQAGDYSLRVDLRAGKEAVFAQYDFFRVDSAKENYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNNLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFQVPTRGT" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:81877", "resource": "KEGG Pathway", "id": "mmu:81877", "name": "" }, { "reaction_list": [ "R-MMU-2318623", "R-MMU-2327909", "R-MMU-2396079", "R-MMU-2396370", "R-MMU-2396395", "R-MMU-2424243", "R-MMU-2424246", "R-MMU-2424252", "R-MMU-2426471", "R-MMU-2466106", "R-MMU-2467665", "R-MMU-2681667", "R-MMU-2681681", "R-MMU-4086132", "R-MMU-4086200" ], "resource": "Reactome", "description": "ECM proteoglycans", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3000178", "id": "R-MMU-3000178", "name": "ECM proteoglycans" } ], "reaction_participants": [], "function": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_112453.2", "annotation": "Mechanical allodynia in mice with tenascin-X deficiency associated with Ehlers-Danlos syndrome. Publication Status: Online-Only", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_112453.2", "id": "NP_112453.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_112453.2", "annotation": "TNX-deficient mice have accelerated gastric emptying and hypersensitivity of gastric vagal mechanoreceptors.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_112453.2", "id": "NP_112453.2", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_112453.2", "annotation": "This study found significant bone loss and upregulation of osteoclast marker gene expression in TNX-deficient mice.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_112453.2", "id": "NP_112453.2", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "P22105-3", "protein_name": "Tenascin-X", "sequence": { "length": 4244, "sequence": "MMPAQYALTSSLVLLVLLSTARAGPFSSRSNVTLPAPRPPPQPGGHTVGAGVGSPSSQLYEHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/49589", "id": "49589", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "TNXB", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006525249.1", "ac": "XP_006525249.1", "name": "tenascin-X isoform X2", "summary": "" }, "reaction_enzymes": [], "site_annotation": [ { "end_pos": 31, "annotation": "n_glycosylation_sequon", "start_pos": 29 }, { "end_pos": 3709, "annotation": "n_glycosylation_sequon", "start_pos": 3707 }, { "end_pos": 3969, "annotation": "n_glycosylation_sequon", "start_pos": 3967 }, { "end_pos": 4022, "annotation": "n_glycosylation_sequon", "start_pos": 4020 }, { "end_pos": 4034, "annotation": "n_glycosylation_sequon", "start_pos": 4032 }, { "end_pos": 4209, "annotation": "n_glycosylation_sequon", "start_pos": 4207 }, { "end_pos": 971, "annotation": "n_glycosylation_sequon", "start_pos": 969 }, { "end_pos": 1000, "annotation": "n_glycosylation_sequon", "start_pos": 998 } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000033327", "id": "ENSMUSG00000033327", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "id": "cd00063", "database": "CDD" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "id": "cd00087", "database": "CDD" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/81877", "id": "81877", "database": "GeneID" }, { "url": "https://acgg.asia/gpdb2/GPDB0002478", "id": "GPDB0002478", "database": "GlycoProtDB" }, { "url": "https://acgg.asia/gpdb2/GPDB0003111", "id": "GPDB0003111", "database": "GlycoProtDB" }, { "url": "https://www.ebi.ac.uk/intact/interactors/id:O35452*", "id": "O35452", "database": "IntAct" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "id": "IPR000742", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "id": "IPR002181", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "id": "IPR003961", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR013111", "id": "IPR013111", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "id": "IPR013783", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR020837", "id": "IPR020837", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR033081", "id": "IPR033081", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "id": "IPR036056", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "id": "IPR036116", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR041161", "id": "IPR041161", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:81877", "id": "mmu:81877", "database": "KEGG Pathway" }, { "url": "http://www.informatics.jax.org/marker/MGI:1932137", "id": "1932137", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/FNLYGMW/", "id": "FNLYGMW", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=18592at2759", "id": "18592at2759", "database": "OrthoDB" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46708:SF3", "id": "PTHR46708:SF3", "database": "PANTHER" }, { "url": "http://pfam.xfam.org/family/PF00041", "id": "PF00041", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00147", "id": "PF00147", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF07974", "id": "PF07974", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF18720", "id": "PF18720", "database": "Pfam" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-3000178", "id": "R-MMU-3000178", "database": "Reactome" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_112453", "id": "NP_112453", "database": "RefSeq" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_112453.2", "id": "NP_112453.2", "database": "RefSeq" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006525249", "id": "XP_006525249", "database": "RefSeq" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006525249.1", "id": "XP_006525249.1", "database": "RefSeq" }, { "url": "https://www.uniprot.org/uniprot/A0A571BG59", "id": "A0A571BG59", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/A0A571BG59-1", "id": "A0A571BG59-1", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "id": "A0A5F8MPH8", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8-1", "id": "A0A5F8MPH8-1", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/E9Q2T3", "id": "E9Q2T3", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/E9Q2T3-1", "id": "E9Q2T3-1", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/O35452", "id": "O35452", "database": "UniProtKB" }, { "url": "https://www.uniprot.org/uniprot/O35452-1", "id": "O35452-1", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [ { "disease_id": "DOID:0080731", "synonyms": [ { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome due to tenascin-X deficiency", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "classical-like EDS", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, classic-like type", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome due to tenascin-X deficiency", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, classic-like", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "EDS, classic-like type", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "classical-like Ehlers-Danlos syndrome", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "clEDS", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "EDSCLL", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "EDS due to Tnx deficiency", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, classic-like; EDSCLL", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos-like syndrome due to tenascin-X deficiency", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "Tnx deficiency", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "TNX deficiency", "id": "MONDO:0011670" }, { "url": "https://monarchinitiative.org/disease/MONDO:0011670", "resource": "MONDO", "description": "", "name": "EDS due to TNX deficiency", "id": "MONDO:0011670" }, { "url": "https://www.omim.org/entry/606408", "resource": "MIM", "description": "Ehlers-Danlos syndrome, classic-like", "name": "Ehlers-Danlos syndrome, classic-like", "id": "MIM:606408" } ], "recommended_name": { "url": "http://disease-ontology.org/term/DOID:0080731", "resource": "Disease Ontology", "description": "An Ehlers-Danlos syndrome that is characterized by hyperextensible skin, hypermobile joints, and tissue fragility and that has_material_basis_in omozygous or heterozygous mutation in the tenascin-XB gene (TNXB) on chromosome 6p21.", "name": "Ehlers-Danlos syndrome classic-like 1", "id": "DOID:0080731" }, "evidence": [ { "url": "https://www.alliancegenome.org/gene/0080731#disease-associations", "id": "0080731", "database": "Alliance of Genome Resources" } ] }, { "disease_id": "DOID:13359", "synonyms": [ { "url": "http://disease-ontology.org/term/DOID:13359", "resource": "Disease Ontology", "description": "", "name": "elastic skin", "id": "DOID:13359" }, { "url": "http://disease-ontology.org/term/DOID:13359", "resource": "Disease Ontology", "description": "", "name": "Cutis hyperelastica", "id": "DOID:13359" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "Ehlers-Danlos syndrome, classic type (cEDS) is a form of Ehlers-Danlos syndrome that affects the connective tissue and is characterized by skin hyperextensibility, widened atrophic scars and joint hypermobility.", "name": "Ehlers-Danlos syndrome, classic type", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome type 2", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, classic type", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "EDS II", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, severe classic type", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "EDS II, formerly", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "EDS I, formerly", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, gravis type", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers Danlos syndrome, mild classic type, formerly", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome type 1 (formerly)", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "EDS I", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, severe classic type, formerly", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers Danlos syndrome, mild classic type", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, type II, formerly", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, type II", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome type 2 (formerly)", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "EDS, classic type", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, gravis type, formerly", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome classical type", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, type I", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "classic Ehlers-Danlos syndrome", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers Danlos syndrome, mitis type, formerly", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, classic type, 1", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "classical Ehlers-Danlos syndrome", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome classic type", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "EDSCL1", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers Danlos syndrome, mitis type", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, classic type, 1; EDSCL1", "id": "MONDO:0007522" }, { "url": "https://monarchinitiative.org/disease/MONDO:0007522", "resource": "MONDO", "description": "", "name": "Ehlers-Danlos syndrome, type I, formerly", "id": "MONDO:0007522" }, { "url": "https://www.omim.org/entry/130000", "resource": "MIM", "description": "Ehlers-Danlos syndrome, classic type, 1", "name": "Ehlers-Danlos syndrome, classic type, 1", "id": "MIM:130000" } ], "recommended_name": { "url": "http://disease-ontology.org/term/DOID:13359", "resource": "Disease Ontology", "description": "A collagen disease that is characterized by extremely flexible joints, elastic skin, and excessive bruising caused by a heritable defect in collagen synthesis, which leads to marked healing difficulties. EDS has five cardinal signs, which may be present to some degree in all of the subtypes. These five cardinal signs are skin fragility, blood vessel fragility, skin hyperelasticity, joint hypermobility, and characteristic subcutaneous nodules.", "name": "Ehlers-Danlos syndrome", "id": "DOID:13359" }, "evidence": [ { "url": "https://www.alliancegenome.org/gene/13359#disease-associations", "id": "13359", "database": "Alliance of Genome Resources" } ] }, { "disease_id": "DOID:9620", "synonyms": [ { "url": "http://disease-ontology.org/term/DOID:9620", "resource": "Disease Ontology", "description": "", "name": "vesico-ureteral reflux", "id": "DOID:9620" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013682", "resource": "MONDO", "description": "", "name": "VUR4", "id": "MONDO:0013682" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013682", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 4; VUR4", "id": "MONDO:0013682" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013682", "resource": "MONDO", "description": "", "name": "VUR4", "id": "MONDO:0013682" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013682", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 4", "id": "MONDO:0013682" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013684", "resource": "MONDO", "description": "", "name": "VUR6", "id": "MONDO:0013684" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013684", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 6; VUR6", "id": "MONDO:0013684" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013684", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 6", "id": "MONDO:0013684" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013684", "resource": "MONDO", "description": "", "name": "VUR6", "id": "MONDO:0013684" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013683", "resource": "MONDO", "description": "", "name": "VUR5", "id": "MONDO:0013683" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013683", "resource": "MONDO", "description": "", "name": "VUR5", "id": "MONDO:0013683" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013683", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 5; VUR5", "id": "MONDO:0013683" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013683", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 5", "id": "MONDO:0013683" }, { "url": "https://monarchinitiative.org/disease/MONDO:0014422", "resource": "MONDO", "description": "Any vesicoureteral reflux in which the cause of the disease is a mutation in the TNXB gene.", "name": "vesicoureteral reflux 8", "id": "MONDO:0014422" }, { "url": "https://monarchinitiative.org/disease/MONDO:0014422", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux (disease) caused by mutation in TNXB", "id": "MONDO:0014422" }, { "url": "https://monarchinitiative.org/disease/MONDO:0014422", "resource": "MONDO", "description": "", "name": "TNXB vesicoureteral reflux (disease)", "id": "MONDO:0014422" }, { "url": "https://monarchinitiative.org/disease/MONDO:0014422", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux type 8", "id": "MONDO:0014422" }, { "url": "https://monarchinitiative.org/disease/MONDO:0014422", "resource": "MONDO", "description": "", "name": "VUR8", "id": "MONDO:0014422" }, { "url": "https://monarchinitiative.org/disease/MONDO:0014422", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 8", "id": "MONDO:0014422" }, { "url": "https://monarchinitiative.org/disease/MONDO:0014422", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 8; VUR8", "id": "MONDO:0014422" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013850", "resource": "MONDO", "description": "", "name": "periodic fever, menstrual cycle-dependent", "id": "MONDO:0013850" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013850", "resource": "MONDO", "description": "", "name": "periodic fever, menstrual cycle-dependent", "id": "MONDO:0013850" }, { "url": "https://monarchinitiative.org/disease/MONDO:0010755", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux, X-linked", "id": "MONDO:0010755" }, { "url": "https://monarchinitiative.org/disease/MONDO:0010755", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux, X-linked", "id": "MONDO:0010755" }, { "url": "https://monarchinitiative.org/disease/MONDO:0010755", "resource": "MONDO", "description": "", "name": "VURX", "id": "MONDO:0010755" }, { "url": "https://monarchinitiative.org/disease/MONDO:0010755", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux, X-linked; VURX", "id": "MONDO:0010755" }, { "url": "https://monarchinitiative.org/disease/MONDO:0012573", "resource": "MONDO", "description": "Any vesicoureteral reflux in which the cause of the disease is a mutation in the ROBO2 gene.", "name": "vesicoureteral reflux 2", "id": "MONDO:0012573" }, { "url": "https://monarchinitiative.org/disease/MONDO:0012573", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 2", "id": "MONDO:0012573" }, { "url": "https://monarchinitiative.org/disease/MONDO:0012573", "resource": "MONDO", "description": "", "name": "ROBO2 vesicoureteral reflux (disease)", "id": "MONDO:0012573" }, { "url": "https://monarchinitiative.org/disease/MONDO:0012573", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 2; VUR2", "id": "MONDO:0012573" }, { "url": "https://monarchinitiative.org/disease/MONDO:0012573", "resource": "MONDO", "description": "", "name": "VUR2", "id": "MONDO:0012573" }, { "url": "https://monarchinitiative.org/disease/MONDO:0012573", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux type 2", "id": "MONDO:0012573" }, { "url": "https://monarchinitiative.org/disease/MONDO:0012573", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux (disease) caused by mutation in ROBO2", "id": "MONDO:0012573" }, { "url": "https://monarchinitiative.org/disease/MONDO:0008653", "resource": "MONDO", "description": "", "name": "VUR1", "id": "MONDO:0008653" }, { "url": "https://monarchinitiative.org/disease/MONDO:0008653", "resource": "MONDO", "description": "", "name": "VUR1", "id": "MONDO:0008653" }, { "url": "https://monarchinitiative.org/disease/MONDO:0008653", "resource": "MONDO", "description": "", "name": "VUR", "id": "MONDO:0008653" }, { "url": "https://monarchinitiative.org/disease/MONDO:0008653", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 1", "id": "MONDO:0008653" }, { "url": "https://monarchinitiative.org/disease/MONDO:0008653", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 1; VUR1", "id": "MONDO:0008653" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013356", "resource": "MONDO", "description": "Any vesicoureteral reflux in which the cause of the disease is a mutation in the SOX17 gene.", "name": "vesicoureteral reflux 3", "id": "MONDO:0013356" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013356", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 3", "id": "MONDO:0013356" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013356", "resource": "MONDO", "description": "", "name": "SOX17 vesicoureteral reflux (disease)", "id": "MONDO:0013356" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013356", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux type 3", "id": "MONDO:0013356" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013356", "resource": "MONDO", "description": "", "name": "VUR3", "id": "MONDO:0013356" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013356", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 3; VUR3", "id": "MONDO:0013356" }, { "url": "https://monarchinitiative.org/disease/MONDO:0013356", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux (disease) caused by mutation in SOX17", "id": "MONDO:0013356" }, { "url": "https://monarchinitiative.org/disease/MONDO:0014161", "resource": "MONDO", "description": "", "name": "VUR7", "id": "MONDO:0014161" }, { "url": "https://monarchinitiative.org/disease/MONDO:0014161", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 7; VUR7", "id": "MONDO:0014161" }, { "url": "https://monarchinitiative.org/disease/MONDO:0014161", "resource": "MONDO", "description": "", "name": "vesicoureteral reflux 7", "id": "MONDO:0014161" }, { "url": "https://monarchinitiative.org/disease/MONDO:0014161", "resource": "MONDO", "description": "", "name": "VUR7", "id": "MONDO:0014161" }, { "url": "https://www.omim.org/entry/615963", "resource": "MIM", "description": "Vesicoureteral reflux 8", "name": "Vesicoureteral reflux 8", "id": "MIM:615963" }, { "url": "https://www.omim.org/entry/614674", "resource": "MIM", "description": "Periodic fever, menstrual cycle-dependent", "name": "Periodic fever, menstrual cycle-dependent", "id": "MIM:614674" }, { "url": "https://www.omim.org/entry/610878", "resource": "MIM", "description": "Vesicoureteral reflux 2", "name": "Vesicoureteral reflux 2", "id": "MIM:610878" }, { "url": "https://www.omim.org/entry/613674", "resource": "MIM", "description": "Vesicoureteral reflux 3", "name": "Vesicoureteral reflux 3", "id": "MIM:613674" } ], "recommended_name": { "url": "http://disease-ontology.org/term/DOID:9620", "resource": "Disease Ontology", "description": "A ureteral disease characterized by backward flow of urine from the urinary bladder into the ureter.", "name": "vesicoureteral reflux", "id": "DOID:9620" }, "evidence": [ { "url": "https://www.alliancegenome.org/gene/9620#disease-associations", "id": "9620", "database": "Alliance of Genome Resources" } ] } ], "phosphorylation": [], "mass": { "monoisotopic_mass": 474063.0, "chemical_mass": 474063.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8", "name": "Tnxb", "locus": { "end_pos": 34719815, "strand": "+", "start_pos": 34670535, "chromosome": "17", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000033327", "id": "ENSMUSG00000033327", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "Tenascin XB" }, { "url": "https://www.uniprot.org/uniprot/A0A5F8MPH8#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "Tenascin X" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A5F8MPH8", "type": "synonym", "resource": "RefSeq", "name": "tenascin-X isoform X2" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A5F8MPH8", "type": "synonym", "resource": "RefSeq", "name": "tenascin-X precursor" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A5F8MPH8", "type": "synonym", "resource": "RefSeq", "name": "tenascin-X" } ] }