{
    "uniprot_canonical_ac": "A0A0G2JTY8-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A0A0G2JTY8-1|A0A0G2JTY8_RAT Isoform 1 of TNFAIP3-interacting protein 3  OS=Rattus norvegicus OX=10116 GN=Tnip3 PE=4 SV=1 CANONICAL=A0A0G2JTY8-1", 
        "length": 208, 
        "sequence": "MAGLSGAGAYMEYTECAAPRRKDLTNSLEQKIKCLEKQRQELLDVNQQWDQQFRNMKELYERKVLELKSKLAAAENTHTLEKKPKQSVTEGDRQLEKEKDILRKELQALKKENKLLKENNAVANRKKEHYACEIKRLNKVLQDALTIGSSLHSEDLGKCKCRGSHAEMRTEVECHKQQPDYQWNALNQLPPHVQHKAHGFSSESKFNL"
    }, 
    "uniprot_id": "", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8", 
                    "id": "A0A0G2JTY8", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8", 
                                "id": "A0A0G2JTY8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "polyubiquitin modification-dependent protein binding", 
                        "id": "GO:0031593"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8", 
                                "id": "A0A0G2JTY8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of transcription by RNA polymerase II", 
                        "id": "GO:0045944"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8", 
                                "id": "A0A0G2JTY8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cellular response to lipopolysaccharide", 
                        "id": "GO:0071222"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8", 
                                "id": "A0A0G2JTY8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of I-kappaB kinase/NF-kappaB signaling", 
                        "id": "GO:0043124"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034142", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8", 
                                "id": "A0A0G2JTY8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "toll-like receptor 4 signaling pathway", 
                        "id": "GO:0034142"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002756", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8", 
                                "id": "A0A0G2JTY8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "MyD88-independent toll-like receptor signaling pathway", 
                        "id": "GO:0002756"
                    }
                ], 
                "total": 5, 
                "name": "Biological Process"
            }
        ]
    }, 
    "publication": [], 
    "uniprot_ac": "A0A0G2JTY8", 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A0G2JTY8", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Tnip3"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Tnip3"
        }
    ], 
    "reactions": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8#A0A0G2JTY8-1", 
            "isoform_ac": "A0A0G2JTY8-1", 
            "locus": {
                "end_pos": 96450271, 
                "strand": "-", 
                "start_pos": 96489866, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000091272", 
                        "id": "ENSRNOT00000091272", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068894", 
                        "id": "ENSRNOP00000068894", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2JTY8-1|A0A0G2JTY8_RAT Isoform 1 of TNFAIP3-interacting protein 3  OS=Rattus norvegicus OX=10116 GN=Tnip3 PE=4 SV=1 CANONICAL=A0A0G2JTY8-1", 
                "length": 208, 
                "sequence": "MAGLSGAGAYMEYTECAAPRRKDLTNSLEQKIKCLEKQRQELLDVNQQWDQQFRNMKELYERKVLELKSKLAAAENTHTLEKKPKQSVTEGDRQLEKEKDILRKELQALKKENKLLKENNAVANRKKEHYACEIKRLNKVLQDALTIGSSLHSEDLGKCKCRGSHAEMRTEVECHKQQPDYQWNALNQLPPHVQHKAHGFSSESKFNL"
            }
        }
    ], 
    "pathway": [
        {
            "reaction_list": [
                "R-RNO-8865182", 
                "R-RNO-5690827", 
                "R-RNO-5690843", 
                "R-RNO-5690845", 
                "R-RNO-5690856", 
                "R-RNO-5690870", 
                "R-RNO-6781905", 
                "R-RNO-6781953", 
                "R-RNO-6783238", 
                "R-RNO-688136", 
                "R-RNO-8869506", 
                "R-RNO-8873946", 
                "R-RNO-8940100"
            ], 
            "resource": "Reactome", 
            "description": "Ovarian tumor domain proteases", 
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5689896", 
            "id": "R-RNO-5689896", 
            "name": "Ovarian tumor domain proteases"
        }
    ], 
    "reaction_participants": [], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A1D5RMN0-1", 
            "protein_name": "TNFAIP3-interacting protein 3", 
            "sequence": {
                "length": 279, 
                "sequence": "MIPRRHLTHEKHDETLVTITHQCEDYERCESMELDDKIRDLIAGGPETTASHRNVHSPKTLRKTASLSSQDMSGLSAAGACMEHTECAPPRRKDLTNSLERKIKHLEKQRQELLDVNQQWDQQFRNMKELYERKVLELKTKLAATENTHTLVKEQKQSVTEGDRQLEKEKDSLRKELQALKKENKLLKENNALANRKKEHYACEIKRLNKVLQDALTIGSSSLSEDSGKCKGRCSHAEMRREVEWHKQQPAYQWNALSQLPPRVQHKAHGFSSERKTDL"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/47979", 
                    "id": "47979", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2JTY8/", 
                    "id": "A0A0G2JTY8", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Tnip3", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q96KP6-1", 
            "protein_name": "TNFAIP3-interacting protein 3", 
            "sequence": {
                "length": 325, 
                "sequence": "MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMYCPPCNCGLVFHLQDPWVPTGPGAVQKQREHPPDYQWYALDQLPPDVQHKANGLSSVKKVHP"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/47979", 
                    "id": "47979", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "TNIP3", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006225015.1", 
        "ac": "XP_006225015.1", 
        "name": "TNFAIP3-interacting protein 3 isoform X5", 
        "summary": ""
    }, 
    "reaction_enzymes": [], 
    "site_annotation": [], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000054524", 
            "id": "ENSRNOG00000054524", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/689756", 
            "id": "689756", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033574", 
            "id": "IPR033574", 
            "database": "InterPro"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/RTEVECH/", 
            "id": "RTEVECH", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=701614at2759", 
            "id": "701614at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31882:SF2", 
            "id": "PTHR31882:SF2", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5689896", 
            "id": "R-RNO-5689896", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006225015", 
            "id": "XP_006225015", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006225015.1", 
            "id": "XP_006225015.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1588732", 
            "id": "1588732", 
            "database": "RGD"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8", 
            "id": "A0A0G2JTY8", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8-1", 
            "id": "A0A0G2JTY8-1", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 24097.0, 
        "chemical_mass": 24097.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8", 
            "name": "Tnip3", 
            "locus": {
                "end_pos": 96492871, 
                "strand": "+", 
                "start_pos": 96449351, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000054524", 
                        "id": "ENSRNOG00000054524", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A0G2JTY8", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "TNFAIP3-interacting protein 3 isoform X5"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY8#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "TNFAIP3-interacting protein 3"
        }
    ]
}