{ "uniprot_canonical_ac": "A4QPH2-1", "ptm_annotation": [], "sequence": { "header": "sp|A4QPH2-1|PI4P2_HUMAN Isoform 1 of Putative phosphatidylinositol 4-kinase alpha-like protein P2 OS=Homo sapiens OX=9606 GN=PI4KAP2 PE=5 SV=3 CANONICAL=A4QPH2-1", "length": 592, "sequence": "MTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGRAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPADIGDLLEQLVEENTGSLSGPAKDFYQRGFDFFNKITNVSAVIKPYPKGDERKKACLSALSEVTVQPGCSLPSNPEAIVLDVDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKLGDDCRQKSYWGARMPTDRILRLPASQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVQATWLCGEPGPYMDVVVSLVTIMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSRTYNMIQYYQNDIPY" }, "uniprot_id": "PI4P2_HUMAN", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Human", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2", "id": "A4QPH2", "database": "UniProtKB" } ], "name": "Homo sapiens", "taxid": 9606 } ], "publication": [], "uniprot_ac": "A4QPH2", "site_annotation": [ { "end_pos": 112, "annotation": "n_glycosylation_sequon", "start_pos": 110 }, { "end_pos": 212, "annotation": "n_glycosylation_sequon", "start_pos": 210 }, { "end_pos": 556, "annotation": "n_glycosylation_sequon", "start_pos": 554 }, { "end_pos": 577, "annotation": "n_glycosylation_sequon", "start_pos": 575 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2#A4QPH2-1", "isoform_ac": "A4QPH2-1", "locus": {}, "sequence": { "header": "sp|A4QPH2-1|PI4P2_HUMAN Isoform 1 of Putative phosphatidylinositol 4-kinase alpha-like protein P2 OS=Homo sapiens OX=9606 GN=PI4KAP2 PE=5 SV=3 CANONICAL=A4QPH2-1", "length": 592, "sequence": "MTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGRAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPADIGDLLEQLVEENTGSLSGPAKDFYQRGFDFFNKITNVSAVIKPYPKGDERKKACLSALSEVTVQPGCSLPSNPEAIVLDVDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKLGDDCRQKSYWGARMPTDRILRLPASQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVQATWLCGEPGPYMDVVVSLVTIMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSRTYNMIQYYQNDIPY" } }, { "url": "https://www.uniprot.org/uniprot/A4QPH2#A4QPH2-2", "isoform_ac": "A4QPH2-2", "locus": {}, "sequence": { "header": "sp|A4QPH2-2|PI4P2_HUMAN Isoform 2 of Putative phosphatidylinositol 4-kinase alpha-like protein P2 OS=Homo sapiens OX=9606 GN=PI4KAP2 PE=5 SV=3 CANONICAL=A4QPH2-1", "length": 439, "sequence": "MTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGRAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPADIGDLLEQLVEENTGSLSGPAKDFYQRGFDFFNKITNVSAVIKPYPKGDERKKACLSALSEVTVQPGCSLPSNPEAIVLDVDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKLGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQVARVATGRGKSCVLHPTPATHTQPLPTPCSPQSSFVKG" } }, { "url": "https://www.uniprot.org/uniprot/A4QPH2#A4QPH2-4", "isoform_ac": "A4QPH2-4", "locus": {}, "sequence": { "header": "sp|A4QPH2-4|PI4P2_HUMAN Isoform 4 of Putative phosphatidylinositol 4-kinase alpha-like protein P2 OS=Homo sapiens OX=9606 GN=PI4KAP2 PE=5 SV=3 CANONICAL=A4QPH2-1", "length": 501, "sequence": "MTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGRAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPADIGDLLEQLVEENTGSLSGPAKDFYQRGFDFFNKITNVSAVIKPYPKGDERKKACLSALSEVTVQPGCSLPSNPEAIVLDVDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKLGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVQATWLCGTGLAPT" } } ], "pathway": [], "function": [], "orthologs": [], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "refseq": {}, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004430", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2", "id": "A4QPH2", "database": "UniProtKB" } ], "name": "1-phosphatidylinositol 4-kinase activity", "id": "GO:0004430" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052742", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2", "id": "A4QPH2", "database": "UniProtKB" } ], "name": "phosphatidylinositol kinase activity", "id": "GO:0052742" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2", "id": "A4QPH2", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2", "id": "A4QPH2", "database": "UniProtKB" } ], "name": "plasma membrane", "id": "GO:0005886" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2", "id": "A4QPH2", "database": "UniProtKB" } ], "name": "membrane", "id": "GO:0016020" } ], "total": 3, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2", "id": "A4QPH2", "database": "UniProtKB" } ], "name": "phosphatidylinositol-mediated signaling", "id": "GO:0048015" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2", "id": "A4QPH2", "database": "UniProtKB" } ], "name": "phosphatidylinositol phosphorylation", "id": "GO:0046854" } ], "total": 2, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2", "type": "recommended", "resource": "UniProtKB", "name": "PI4KAP2" } ], "pro_annotation": [], "crossref": [ { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A4QPH2", "id": "A4QPH2", "database": "BioMuta" }, { "url": "https://www.ebi.ac.uk/chembldb/target/inspect/CHEMBL4105789", "id": "CHEMBL4105789", "database": "ChEMBL" }, { "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=PI4KAP2", "id": "PI4KAP2", "database": "GeneCards" }, { "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=33577", "id": "33577", "database": "HGNC" }, { "url": "https://www.ebi.ac.uk/intact/interactors/id:A4QPH2*", "id": "A4QPH2", "database": "IntAct" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000403", "id": "IPR000403", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "id": "IPR011009", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR015433", "id": "IPR015433", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR018936", "id": "IPR018936", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036940", "id": "IPR036940", "database": "InterPro" }, { "url": 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"https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A4QPH2", "id": "A4QPH2", "database": "BioXpress" } ], "url": "http://disease-ontology.org/term/DOID:5041", "significant": "No" } ], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 66944.0, "chemical_mass": 66944.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2", "name": "PI4KAP2", "locus": { "end_pos": 21473000, "strand": "-", "start_pos": 21517533, "chromosome": "22", "evidence": [ { "url": "https://www.ensembl.org/id/ENSG00000183506", "id": "ENSG00000183506", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A4QPH2#names_and_taxonomy", "type": "recommended", "resource": "UniProtKB", "name": "Putative phosphatidylinositol 4-kinase alpha-like protein P2" } ] }