{
    "uniprot_canonical_ac": "A2VD13-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2VD13-1|PTCD1_RAT Isoform 1 of Pentatricopeptide repeat-containing protein 1, mitochondrial  OS=Rattus norvegicus OX=10116 GN=Ptcd1 PE=2 SV=1 CANONICAL=A2VD13-1", 
        "length": 686, 
        "sequence": "MDLLRLSRLFSGPHPIGLSVLQRLDLLRSTQWTGGREGPAWLRAASCSSSSHQKRMSSLCSDSSTPVAPQEEEEEESFGTLSEKFSSRRIFHKSTAQLYNLKLKEQGVEEEELEPRLRQGGRNTPYWYFLQCKRLLKEGKLAEALDLFERQMLKEERLQPLECNYTVLIGGCGRVGYLKKAFRLFNDMKKRDLEPSDATYTALFNVCAESPWKDSALQSALKLRQQLQAQNFQLNLKTYHALLKVAAKCADLRVCLEVFKEIIQKGHAVTEETFCFLLMGCIQDKKTGFRQAMQVWRQMLSLGIKPSRHGYNLLLGAARDCGLGDPEVASRLLLTSQEETILLQPPTGRRLAGGKVQAKTRHGVSVKHVEALERQLFLEPSHKLEGPPAFPEARETSRTQPEVETKAEPGHMGALAPLALKPPDLELQVNLLSLGALSPAVVSFGTVATPADRLALMGGLEGFLGKMAEHRLQPDIKTLTLLAEVVEPGSPAESSLLSILDRHRVEADITFFNTLIRKKSKLGDLEGAKALLPILAKKGIVPNLRTFCNLAIGCHRPRDGMQLLADMKKSQVTPNTHIYSTLINAALKKLDYTYLISILKDMRRNSVPVNEVVIRQLEFAAQYPPTFDRYKEKNTYLEKIDGFRAYYKQWLKVMPAEEPPHPWQEFRDKPVRNQVITENAGGLRDG"
    }, 
    "uniprot_id": "PTCD1_RAT", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2VD13", 
                    "id": "A2VD13", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/19651879", 
                    "type": "PubMed", 
                    "id": "19651879"
                }
            ], 
            "title": "Pentatricopeptide repeat domain protein 1 lowers the levels of mitochondrial leucine tRNAs in cells.", 
            "journal": "Nucleic Acids Res.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2VD13", 
                    "id": "A2VD13", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Whelan J., Rackham O., Filipovska A., Davies S.M., Hamilton K.L., Shearwood A.M.", 
            "date": "2009"
        }
    ], 
    "uniprot_ac": "A2VD13", 
    "site_annotation": [
        {
            "end_pos": 166, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 164
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2VD13#A2VD13-1", 
            "isoform_ac": "A2VD13-1", 
            "locus": {
                "end_pos": 11217951, 
                "strand": "-", 
                "start_pos": 11232712, 
                "chromosome": "12", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000076896", 
                        "id": "ENSRNOT00000076896", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068093", 
                        "id": "ENSRNOP00000068093", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2VD13-1|PTCD1_RAT Isoform 1 of Pentatricopeptide repeat-containing protein 1, mitochondrial  OS=Rattus norvegicus OX=10116 GN=Ptcd1 PE=2 SV=1 CANONICAL=A2VD13-1", 
                "length": 686, 
                "sequence": "MDLLRLSRLFSGPHPIGLSVLQRLDLLRSTQWTGGREGPAWLRAASCSSSSHQKRMSSLCSDSSTPVAPQEEEEEESFGTLSEKFSSRRIFHKSTAQLYNLKLKEQGVEEEELEPRLRQGGRNTPYWYFLQCKRLLKEGKLAEALDLFERQMLKEERLQPLECNYTVLIGGCGRVGYLKKAFRLFNDMKKRDLEPSDATYTALFNVCAESPWKDSALQSALKLRQQLQAQNFQLNLKTYHALLKVAAKCADLRVCLEVFKEIIQKGHAVTEETFCFLLMGCIQDKKTGFRQAMQVWRQMLSLGIKPSRHGYNLLLGAARDCGLGDPEVASRLLLTSQEETILLQPPTGRRLAGGKVQAKTRHGVSVKHVEALERQLFLEPSHKLEGPPAFPEARETSRTQPEVETKAEPGHMGALAPLALKPPDLELQVNLLSLGALSPAVVSFGTVATPADRLALMGGLEGFLGKMAEHRLQPDIKTLTLLAEVVEPGSPAESSLLSILDRHRVEADITFFNTLIRKKSKLGDLEGAKALLPILAKKGIVPNLRTFCNLAIGCHRPRDGMQLLADMKKSQVTPNTHIYSTLINAALKKLDYTYLISILKDMRRNSVPVNEVVIRQLEFAAQYPPTFDRYKEKNTYLEKIDGFRAYYKQWLKVMPAEEPPHPWQEFRDKPVRNQVITENAGGLRDG"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2VD13#D4AA10-1", 
            "isoform_ac": "D4AA10-1", 
            "locus": {
                "end_pos": 11217951, 
                "strand": "-", 
                "start_pos": 11232712, 
                "chromosome": "12", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000060924", 
                        "id": "ENSRNOT00000060924", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000057644", 
                        "id": "ENSRNOP00000057644", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|D4AA10-1|PTCD1_RAT Computationally mapped isoform of Pentatricopeptide repeat-containing protein 1, mitochondrial  OS=Rattus norvegicus OX=10116 GN=Ptcd1 PE=2 SV=1 CANONICAL=A2VD13-1", 
                "length": 652, 
                "sequence": "MDLLRLSRLFSGPHPIGLSVLQRLDLLRSTQWTGGREGPAWLRAASCSSSSHQKRMSSLCSDSSTPVAPQEEEEEESFGTLSEKFSSRRIFHKSTAQLYNLKLKEQGVEEEELEPRLRQGGRNTPYWYFLQCKRLLKEGKLAEALDLFERQMLKEERLQPLECNYTVLIGGCGRVGYLKKAFRLFNDMKKRDLEPSDATYTALFNVCAESPWKDSALQSALKLRQQLQAQNFQLNLKTYHALLKVAAKCADLRVCLEVFKVWRQMLSLGIKPSRHGYNLLLGAARDCGLGDPEVASRLLLTSQEETILLQPPTGRRLAGGKVQAKTRHGVSVKHVEALERQLFLEPSHKLEGPPAFPEARETSRTQPEVETKAEPGHMGALAPLALKPPDLELQVNLLSLGALSPAVVSFGTVATPADRLALMGGLEGFLGKMAEHRLQPDIKTLTLLAEVVEPGSPAESSLLSILDRHRVEADITFFNTLIRKKSKLGDLEGAKALLPILAKKGIVPNLRTFCNLAIGCHRPRDGMQLLADMKKSQVTPNTHIYSTLINAALKKLDYTYLISILKDMRRNSVPVNEVVIRQLEFAAQYPPTFDRYKEKNTYLEKIDGFRAYYKQWLKVMPAEEPPHPWQEFRDKPVRNQVITENAGGLRDG"
            }
        }
    ], 
    "pathway": [], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A2VD13#function", 
            "annotation": "Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria-encoded proteins and COX activity. Affects also the 3'-processing of mitochondrial tRNAs.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2VD13#function", 
                    "id": "A2VD13", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q8C2E4-1", 
            "protein_name": "Pentatricopeptide repeat-containing protein 1, mitochondrial", 
            "sequence": {
                "length": 695, 
                "sequence": "MDLLRLSRLFSGPRPIGLSVLQHLDLVGSTRWTGGREGPARLRAAFCGSSSPLPLGSGNQKEMSSLCSDSSKLSTVAPQEEAEEESFGSLSGKFSSRRIFHKSTAQLYNLQLKEQGGEEEELEPRPWRGRRNTQYWYFFQCKRLIKEGKLAEALDLFERQMLKEERLQPLECNYTVLIGGCGRVGYLKKAFRLFNDMKKRDLEPSDATYTALFNVCAESPWKDSALQSALKLRQQLQARNFQLNLKTYHALLKVAAKCADLRLCLDVFKEIIQRGHAVTEETFCFLLVGCIQDKKTGFRQAMQVWRQMLSLGIKPSRHGYNLLLEAARDCGLGDPEVASRLLLTSQEETILLPPPKGRHMAGRKVQAKTVHGVSLRHVEALERQLFLEPSQKLEGPPALPEARVTSRTQPEVETTAEPGHTVALTPLASKPTHLELEVSLLSLGTLSPAVVSFGTVATPADRLALMGGLEGFLGKMTEHGLQPDIKTLTLLAEVVEPGSTAESSLLSVLDRHRVEADVTFFNTLIRKKSKLGDLEGAKALLPILAKKGIVPNLRTFCNLAIGCHRPRDGMQLLADMKKSQVSPNIHIYSTLINAALKKLDYTYLISILKDMRQNSVPVNEVVVRQLEFAAEYPPTFDRYKGKNTYLEKIDGFRAYYKQWLKAMPAEEAPHPWQEFQNKPVGDQDTTDKAGGLRDG"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/33161", 
                    "id": "33161", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A2VD13/", 
                    "id": "A2VD13", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Ptcd1", 
            "tax_id": 10090
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006248933.1", 
        "ac": "XP_006248933.1", 
        "name": "pentatricopeptide repeat-containing protein 1, mitochondrial isoform X1", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2VD13", 
                                "id": "A2VD13", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "tRNA binding", 
                        "id": "GO:0000049"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", 
                        "pmid": "19651879", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2VD13", 
                                "id": "A2VD13", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mitochondrial matrix", 
                        "id": "GO:0005759"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042780", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2VD13", 
                                "id": "A2VD13", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "tRNA 3'-end processing", 
                        "id": "GO:0042780"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2VD13", 
                                "id": "A2VD13", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mitochondrial translation", 
                        "id": "GO:0032543"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2VD13", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Ptcd1"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2VD13", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Ptcd1"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000000987", 
            "id": "ENSRNOG00000000987", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/304278", 
            "id": "304278", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002885", 
            "id": "IPR002885", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", 
            "id": "IPR011990", 
            "database": "InterPro"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/KCADLRM/", 
            "id": "KCADLRM", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1344243at2759", 
            "id": "1344243at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF13041", 
            "id": "PF13041", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF13812", 
            "id": "PF13812", 
            "database": "Pfam"
        }, 
        {
            "url": "http://purl.obolibrary.org/obo/PR_PR_A2VD13", 
            "id": "PR_A2VD13", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006248933", 
            "id": "XP_006248933", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006248933.1", 
            "id": "XP_006248933.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1311473", 
            "id": "1311473", 
            "database": "RGD"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2VD13", 
            "id": "A2VD13", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 77121.0, 
        "chemical_mass": 77121.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2VD13", 
            "name": "Ptcd1", 
            "locus": {
                "end_pos": 11233633, 
                "strand": "+", 
                "start_pos": 11215886, 
                "chromosome": "12", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000000987", 
                        "id": "ENSRNOG00000000987", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2VD13#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Pentatricopeptide repeat-containing protein 1, mitochondrial"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2VD13", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "pentatricopeptide repeat-containing protein 1, mitochondrial isoform X1"
        }
    ]
}