{
    "uniprot_canonical_ac": "A2RRT9-1", 
    "publication_count": 3, 
    "reported_interactions": 0, 
    "record_type": "protein", 
    "predicted_glycosites": 0, 
    "protein_names_refseq": "cytochrome P450 4V2; cytochrome P450-like protein; cytochrome P450 4V3; docosahexaenoic acid omega-hydroxylase CYP4V2; long-chain fatty acid omega-monooxygenase", 
    "refseq_ac": "NP_001129072.1", 
    "reported_n_glycosites": 0, 
    "refseq_name": "cytochrome P450 4V2", 
    "record_id": "A2RRT9-1", 
    "protein_names_uniprotkb": "Cytochrome P450 4V2; 1.14.14.79; 1.14.14.80; Docosahexaenoic acid omega-hydroxylase CYP4V2; Long-chain fatty acid omega-monooxygenase", 
    "pathway": " (rno:266761); Endogenous sterols (R-RNO-211976); The canonical retinoid cycle in rods (twilight vision) (R-RNO-2453902)", 
    "function": "A cytochrome P450 monooxygenase involved in fatty acid metabolism in the eye. Catalyzes the omega-hydroxylation of polyunsaturated fatty acids (PUFAs) docosahexaenoate (DHA) and its precursor eicosapentaenoate (EPA), and may contribute to the homeostasis of these retinal PUFAs. Omega hydroxylates saturated fatty acids such as laurate, myristate and palmitate, the catalytic efficiency decreasing in the following order: myristate > laurate > palmitate (C14>C12>C16). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase)., [UniProtKB]; Tissue kallikrein mRNA expression is increased during prenatal and early postnatal development stages in rat brain., [RefSeq]", 
    "protein_name": "Cytochrome P450 4V2", 
    "reported_mutagensis": 0, 
    "reported_phosphosites": 0, 
    "reported_o_glycosites_with_glycan": 0, 
    "tax_id": 10116, 
    "organism": "Rattus norvegicus", 
    "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664)", 
    "reported_glycation": 0, 
    "reported_snv": 0, 
    "mass": 60580.0, 
    "gene_names_uniprotkb": "Cyp4v2; Cyp4v3", 
    "reported_n_glycosites_with_glycan": 0, 
    "reported_o_glycosites": 0, 
    "gene_names_refseq": "Cyp4v2; Cyp4v3", 
    "gene_name": "Cyp4v2"
}