{
    "uniprot_canonical_ac": "A2ATD1-1", 
    "publication_count": 4, 
    "reported_interactions": 0, 
    "record_type": "protein", 
    "predicted_glycosites": 0, 
    "protein_names_refseq": "isthmin 1 homolog; isthmin-1 precursor", 
    "refseq_ac": "NP_001263418.1", 
    "reported_n_glycosites": 0, 
    "refseq_name": "isthmin-1 precursor", 
    "record_id": "A2ATD1-1", 
    "protein_names_uniprotkb": "Isthmin-1; Isthmin-1", 
    "pathway": " (mmu:319909)", 
    "function": "Acts as an angiogenesis inhibitor., [UniProtKB]; Given that ISM1 has been reported to have anti-angiogenic properties, these observations suggest that ISM1 is a mediator of lymphocyte effector functions and may participate in both innate and acquired immune responses., [RefSeq]; ISM is a novel vascular permeability inducer that functions through cell-surface GRP78-mediated Src activation as well as induction of apoptosis, [RefSeq]; ISM1 transcripts are found in tissues as the anterior mesendoderm, paraxial and lateral plate mesoderm, MHB and trunk neural tube, as well as in the somites and dermomyotome. In the newborn and adult, ISM1 is prominently expressed in the lung and brain., [RefSeq]; Results demonstrate that Isthmin is a novel endogenous angiogenesis inhibitor with functions likely in physiological as well as pathological angiogenesis., [RefSeq]", 
    "protein_name": "Isthmin-1", 
    "reported_mutagensis": 0, 
    "reported_phosphosites": 0, 
    "reported_o_glycosites_with_glycan": 0, 
    "tax_id": 10090, 
    "organism": "Mus musculus", 
    "disease": "", 
    "reported_glycation": 0, 
    "reported_snv": 0, 
    "mass": 51145.0, 
    "gene_names_uniprotkb": "Ism1; Ism", 
    "reported_n_glycosites_with_glycan": 0, 
    "reported_o_glycosites": 0, 
    "gene_names_refseq": "5430433G21Rik; Ism; Ism1", 
    "gene_name": "Ism1"
}